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The map label for this gene is yhcY [H]

Identifier: 221635976

GI number: 221635976

Start: 564093

End: 565340

Strand: Reverse

Name: yhcY [H]

Synonym: trd_A0570

Alternate gene names: 221635976

Gene position: 565340-564093 (Counterclockwise)

Preceding gene: 221635980

Following gene: 221635975

Centisome position: 61.6

GC content: 63.46

Gene sequence:

>1248_bases
ATGATCACGCGTCTCCCAGAGTTGGGTCCGACCGCTGAGCGAGATGACTGGCAGGCACAGCTCGAATCGCTCTACGCCAT
TTCCGTGGAGATCGCGAGTCTGCGCGAGCTCAGTGCAGTCATGGATCGGGCGCTCGAGTACTGCTTGGCGTTGACGACCT
CCGCCTTCGGCTTCGTCGGATTGGTCGACGGACCGGAAACGATGGACGTGGCGGCCATCCGCGGTTTCGTCCCTGATGGA
TCGGATTTCTATGAGCGGTTCCGCAAGATCCCGATTCGCCGCACGATCTTCGGGGTCGTGATCCTCGAGGGGCGACCGAA
TATCTCCAACGACGTGCGCAACGATCCCCTCCATCGTGGTGCACCGCGGGGACATCCACCGGTGGAGACCTTCCTGGGGG
TTCCGCTCAGGGTGCGGCAGCAAACGATCGGGATGATCGGTGTAGCCAATCGCCCCTCTGGGTACGACGCGCGTCACGAG
CGGTTGCTCAGTACGTTCGCGAATCAGGTTGCGGTCGCGATCGAAAATGCACGGCTCTATGAGCGGCAGCGACAAATGAT
CGCTGACCTCCAGCAACTGCATGCGCGCCTCGATGCCGCGCGGGTCGAGGCGCTCCTCCATCAGGAACGCAATCGGATCG
CGGCGGACTTGCACGATCGAGTCGCGCAGATCATGTTCGGGATCGGGATCGAAGCGACGTGGTGCCGGGACCAGCCGGAT
GTGCCGGAGCCGGTCCTGCGTGCGCTCGACCGCATCCGGGAACTTGCTGCGCGAGGGGCAGCCGAGGTACGCCGGGTCGT
TTACGATCTGGCTGAGATGCCAGTCGGTGGGGGTGAACTCGTCGAGCGCATCCGACAGCTGGTGGAGGGGTACCGAAGCG
AGGACTTGCGGGTCGAACTGGTGATCGAGGGCAAGCCGCGTCGCTTGCCTCCGGAGCGCGAAGACGCGATTTTCCTCATC
GCGTGCGAGGCGTTGACGAATGTTCGTCGGCATTCGGGGGCGGATCTCGCCATCGTGAGTTTGCACTTCACTGAACGATC
GGTCATCCTCGTCGTACAGGACAATGGCTGTGGGATGCCGCACACCTCGTTCGTCTCGGTGCGGACGGCCGGGCACTTCG
GGTTGCGATCGATGCGCCGTCGAGCCGAAGCGGTCGGCGGGGAACTCTCCTGGTACAACGGCGAAGATGGTGGGTTCGTC
GTGCGGGCGGTGATACCAGCTGAGCCACGATGGGCGGAGCAGGTGTGA

Upstream 100 bases:

>100_bases
CCCCGGCACCGTGCCGATCGTACCCGATCTCTCTGGATACGGGTAGCTGAGCGGAGACGGCACAGGTGCATGGTACACTG
CGTGCAGCCGGAGGTCTTCG

Downstream 100 bases:

>100_bases
GCTGGCAGCCACTGCGGGTGGCCATCATCGACGATCACGAGATCGTGCGGAACGGCCTCAAGCACATCCTCGCCGACGAT
CCGGACTTCCTGGTGGTGGG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MITRLPELGPTAERDDWQAQLESLYAISVEIASLRELSAVMDRALEYCLALTTSAFGFVGLVDGPETMDVAAIRGFVPDG
SDFYERFRKIPIRRTIFGVVILEGRPNISNDVRNDPLHRGAPRGHPPVETFLGVPLRVRQQTIGMIGVANRPSGYDARHE
RLLSTFANQVAVAIENARLYERQRQMIADLQQLHARLDAARVEALLHQERNRIAADLHDRVAQIMFGIGIEATWCRDQPD
VPEPVLRALDRIRELAARGAAEVRRVVYDLAEMPVGGGELVERIRQLVEGYRSEDLRVELVIEGKPRRLPPEREDAIFLI
ACEALTNVRRHSGADLAIVSLHFTERSVILVVQDNGCGMPHTSFVSVRTAGHFGLRSMRRRAEAVGGELSWYNGEDGGFV
VRAVIPAEPRWAEQV

Sequences:

>Translated_415_residues
MITRLPELGPTAERDDWQAQLESLYAISVEIASLRELSAVMDRALEYCLALTTSAFGFVGLVDGPETMDVAAIRGFVPDG
SDFYERFRKIPIRRTIFGVVILEGRPNISNDVRNDPLHRGAPRGHPPVETFLGVPLRVRQQTIGMIGVANRPSGYDARHE
RLLSTFANQVAVAIENARLYERQRQMIADLQQLHARLDAARVEALLHQERNRIAADLHDRVAQIMFGIGIEATWCRDQPD
VPEPVLRALDRIRELAARGAAEVRRVVYDLAEMPVGGGELVERIRQLVEGYRSEDLRVELVIEGKPRRLPPEREDAIFLI
ACEALTNVRRHSGADLAIVSLHFTERSVILVVQDNGCGMPHTSFVSVRTAGHFGLRSMRRRAEAVGGELSWYNGEDGGFV
VRAVIPAEPRWAEQV
>Mature_415_residues
MITRLPELGPTAERDDWQAQLESLYAISVEIASLRELSAVMDRALEYCLALTTSAFGFVGLVDGPETMDVAAIRGFVPDG
SDFYERFRKIPIRRTIFGVVILEGRPNISNDVRNDPLHRGAPRGHPPVETFLGVPLRVRQQTIGMIGVANRPSGYDARHE
RLLSTFANQVAVAIENARLYERQRQMIADLQQLHARLDAARVEALLHQERNRIAADLHDRVAQIMFGIGIEATWCRDQPD
VPEPVLRALDRIRELAARGAAEVRRVVYDLAEMPVGGGELVERIRQLVEGYRSEDLRVELVIEGKPRRLPPEREDAIFLI
ACEALTNVRRHSGADLAIVSLHFTERSVILVVQDNGCGMPHTSFVSVRTAGHFGLRSMRRRAEAVGGELSWYNGEDGGFV
VRAVIPAEPRWAEQV

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=310, Percent_Identity=28.3870967741935, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46412; Mature: 46412

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRLPELGPTAERDDWQAQLESLYAISVEIASLRELSAVMDRALEYCLALTTSAFGFVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LVDGPETMDVAAIRGFVPDGSDFYERFRKIPIRRTIFGVVILEGRPNISNDVRNDPLHRG
ECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHEEEEEEEECCCCCCCCCCCCCCCCCC
APRGHPPVETFLGVPLRVRQQTIGMIGVANRPSGYDARHERLLSTFANQVAVAIENARLY
CCCCCCCHHHHHCCCHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERQRQMIADLQQLHARLDAARVEALLHQERNRIAADLHDRVAQIMFGIGIEATWCRDQPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
VPEPVLRALDRIRELAARGAAEVRRVVYDLAEMPVGGGELVERIRQLVEGYRSEDLRVEL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEE
VIEGKPRRLPPEREDAIFLIACEALTNVRRHSGADLAIVSLHFTERSVILVVQDNGCGMP
EECCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCC
HTSFVSVRTAGHFGLRSMRRRAEAVGGELSWYNGEDGGFVVRAVIPAEPRWAEQV
CCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MITRLPELGPTAERDDWQAQLESLYAISVEIASLRELSAVMDRALEYCLALTTSAFGFVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LVDGPETMDVAAIRGFVPDGSDFYERFRKIPIRRTIFGVVILEGRPNISNDVRNDPLHRG
ECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHEEEEEEEECCCCCCCCCCCCCCCCCC
APRGHPPVETFLGVPLRVRQQTIGMIGVANRPSGYDARHERLLSTFANQVAVAIENARLY
CCCCCCCHHHHHCCCHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERQRQMIADLQQLHARLDAARVEALLHQERNRIAADLHDRVAQIMFGIGIEATWCRDQPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
VPEPVLRALDRIRELAARGAAEVRRVVYDLAEMPVGGGELVERIRQLVEGYRSEDLRVEL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEE
VIEGKPRRLPPEREDAIFLIACEALTNVRRHSGADLAIVSLHFTERSVILVVQDNGCGMP
EECCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCC
HTSFVSVRTAGHFGLRSMRRRAEAVGGELSWYNGEDGGFVVRAVIPAEPRWAEQV
CCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]