Click here to switch to the map view.

The map label for this gene is yuxL [H]

Identifier: 221635973

GI number: 221635973

Start: 560816

End: 562819

Strand: Reverse

Name: yuxL [H]

Synonym: trd_A0567

Alternate gene names: 221635973

Gene position: 562819-560816 (Counterclockwise)

Preceding gene: 221635974

Following gene: 221635972

Centisome position: 61.33

GC content: 64.17

Gene sequence:

>2004_bases
GTGGTTCTCGACAGCGAGGAGGTGAAGGTGAGCGAGAACGCAACGACCATCCTCACGGTCGATGAATTGGTCACGATGCA
ACGCCCCTTCGATGTCGAGGTGGCTCCGGACGGAGAGACGATCGTCTATGTGGTTCGCCCGGTCAGTCGGGAAGAGGAGC
ACTGGCGGAGTAGCCTGTGGATCGTGCCGTTCATGGAGGGAGAGGCTCGCCAGTTCACGAGTGGACTCTGGCACGATCGG
GAACCGCGCTGGTCGCCTGACGGCGGGTGGATCGCGTTCTTGTCCGACCGGGCCGAACGTGGGAAAACCAGTGTCTATCT
GATACCGCGGAACGGAGGCGAGGCGCTTCGTGTTTTCGATCAGGCGGGTGAGATCGATAACCTCAGTTGGTCTCCTGACG
GGCGGTTTCTCGCGTTCCTCATGGTCGAACCGGAGACCGAGGAAGAGAAGCAGCGCCGCGAGCGGCGCGACGATGCGCGC
GTGTGGGATGCTGACTGGAAGTATCGGCGGTTGTGGCTGCTCGATGTGCGGACGCGCGCGGCGCGTGTCGTCTCGCCAGA
GCGCGTGCAGGTCTGGGCATACGCCTGGGCACCGGACAGTGCACGACTGGCTTTGGCGGTCAGCGGAACCCCGCGAGTGG
ACGATGTGTTCCGGGTGACCAGCGTGGCGCTGCTGGATATCGAGAGTGGCGAGTACCGTGAACTCTTCACGATGCGTGGG
GTTGCGGAGGACCTGGTGTGGTCGGCTGATGGCGAGTGGCTGGCCTATCGCGGCCCGCTGGGTCGGGTGGTGCACGGGGA
AGCGGTCTTCCGACGGCGAGTACGGGGAGGCGAGGCGGAGTGCCTGACTGCGGGATATCGGGGAACAGTCGAGCATCTGG
GCCCCTATCGCCAAGGTGAAGCGCTGGTCGTGGTGGGGTACGAGGGACTGGACGCGCGGGTTTATCGGCTGGAGTGGGAC
GGAGAACAGCGCCTGCTGTGCCCCCGGACGACGGGGAGCTGGCACGGGAGGGTGAGCGGGAGTGGAGACGGCACGAGGTG
GGCGGGGGTGTGGTCGGATGCAGAGCATGTGCCGGACGTGTGGTGCTGGCGCGTCTCCAACGACATATCCCTCGGTGACA
CTACTCTGCAGCGGCGCACCCACCTCCACCCAGAGATCGAAGCCAAACTATGCCCAGCTCGCAGCATCGAATGGACCAGT
GACCCGGGAGTGACCGTGCAAGGGCTTCTCGTTCTCCCGCGAGACGGGACAGCCAAGCCCCCGTATCCGCTCGTCGTGCA
GATTCACGGCGGTCCGACGAGTCAGTGGGCCAACGAGTTCGTGGCGTCCTGGCACGACTGGGCGCAACCTCTCGCATCCC
GCGGCTGTGCAGTCCTCCTCCCAAACCCACGCGGCAGCACTGGCCGTGGCACACAGTGGATCAACGCACTGTTCGGCGAT
GTGGGAGGCGGCGAGTACCGGGATGTGGTCAGCGGCGTCGAGGCGCTCGTCGCAGCTGGACTCGCCGATCCTTTCCGACT
CGGTGTGAGCGGATGGAGTTGGGGTGGATACCTGACAGCCTGGACGATCACTCAGACCGACCGCTTCCGTGCCGCCTTCA
TGGGAGCTGGCCTCTGCAACTTGATCAGCGACAACAACCTCGGCGATATCCCCTCGGCGAATCTCTCGTATTTCGAGCGG
TCACCCTCGGAGGATCCTGAGCCGTACTGGGACCGTTCGCCGATCCGTTACGTGCAGCGAGTCCGAACTCCTGTGCTCAT
CGCTCATGGGGAAGATGACGAGCGGGTCAGCGTCTGCGAAAGCATCCAATTCTACCGAGCCCTGCAGATCCTCGAAAAAC
CATGCCAACTCGTGACCTACCCGCGTGAGAAGCACGGCTTCGAGGAACGGAACCACCAGCGAGACCTCTTGACGCGCATC
CTGCAGTGGTTCGCTCAGCATCTCGACCTAGAGGCGCCCGAGCGGGTCACGATGGCAACGACGGCGCCCTCGGCAAGCGG
ATGA

Upstream 100 bases:

>100_bases
CGAGATCGAGGAGTCAATGCCGGGGGACATCGACACGTGGGAGGACTACGAGGCGAGCCGACGGAGAGGGGTCTGACGCG
CTCCTCACGACATATCCCTC

Downstream 100 bases:

>100_bases
GGAGACGAATCGGACGCCTGCCAGATCGGCGCGCTTGCTCGCTGACCACTCAGCATGCCAAGACACCCCTCCGATCGGAA
GGGCGAACACCCTCCGATCG

Product: peptidase S9, prolyl oligopeptidase active site domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MVLDSEEVKVSENATTILTVDELVTMQRPFDVEVAPDGETIVYVVRPVSREEEHWRSSLWIVPFMEGEARQFTSGLWHDR
EPRWSPDGGWIAFLSDRAERGKTSVYLIPRNGGEALRVFDQAGEIDNLSWSPDGRFLAFLMVEPETEEEKQRRERRDDAR
VWDADWKYRRLWLLDVRTRAARVVSPERVQVWAYAWAPDSARLALAVSGTPRVDDVFRVTSVALLDIESGEYRELFTMRG
VAEDLVWSADGEWLAYRGPLGRVVHGEAVFRRRVRGGEAECLTAGYRGTVEHLGPYRQGEALVVVGYEGLDARVYRLEWD
GEQRLLCPRTTGSWHGRVSGSGDGTRWAGVWSDAEHVPDVWCWRVSNDISLGDTTLQRRTHLHPEIEAKLCPARSIEWTS
DPGVTVQGLLVLPRDGTAKPPYPLVVQIHGGPTSQWANEFVASWHDWAQPLASRGCAVLLPNPRGSTGRGTQWINALFGD
VGGGEYRDVVSGVEALVAAGLADPFRLGVSGWSWGGYLTAWTITQTDRFRAAFMGAGLCNLISDNNLGDIPSANLSYFER
SPSEDPEPYWDRSPIRYVQRVRTPVLIAHGEDDERVSVCESIQFYRALQILEKPCQLVTYPREKHGFEERNHQRDLLTRI
LQWFAQHLDLEAPERVTMATTAPSASG

Sequences:

>Translated_667_residues
MVLDSEEVKVSENATTILTVDELVTMQRPFDVEVAPDGETIVYVVRPVSREEEHWRSSLWIVPFMEGEARQFTSGLWHDR
EPRWSPDGGWIAFLSDRAERGKTSVYLIPRNGGEALRVFDQAGEIDNLSWSPDGRFLAFLMVEPETEEEKQRRERRDDAR
VWDADWKYRRLWLLDVRTRAARVVSPERVQVWAYAWAPDSARLALAVSGTPRVDDVFRVTSVALLDIESGEYRELFTMRG
VAEDLVWSADGEWLAYRGPLGRVVHGEAVFRRRVRGGEAECLTAGYRGTVEHLGPYRQGEALVVVGYEGLDARVYRLEWD
GEQRLLCPRTTGSWHGRVSGSGDGTRWAGVWSDAEHVPDVWCWRVSNDISLGDTTLQRRTHLHPEIEAKLCPARSIEWTS
DPGVTVQGLLVLPRDGTAKPPYPLVVQIHGGPTSQWANEFVASWHDWAQPLASRGCAVLLPNPRGSTGRGTQWINALFGD
VGGGEYRDVVSGVEALVAAGLADPFRLGVSGWSWGGYLTAWTITQTDRFRAAFMGAGLCNLISDNNLGDIPSANLSYFER
SPSEDPEPYWDRSPIRYVQRVRTPVLIAHGEDDERVSVCESIQFYRALQILEKPCQLVTYPREKHGFEERNHQRDLLTRI
LQWFAQHLDLEAPERVTMATTAPSASG
>Mature_667_residues
MVLDSEEVKVSENATTILTVDELVTMQRPFDVEVAPDGETIVYVVRPVSREEEHWRSSLWIVPFMEGEARQFTSGLWHDR
EPRWSPDGGWIAFLSDRAERGKTSVYLIPRNGGEALRVFDQAGEIDNLSWSPDGRFLAFLMVEPETEEEKQRRERRDDAR
VWDADWKYRRLWLLDVRTRAARVVSPERVQVWAYAWAPDSARLALAVSGTPRVDDVFRVTSVALLDIESGEYRELFTMRG
VAEDLVWSADGEWLAYRGPLGRVVHGEAVFRRRVRGGEAECLTAGYRGTVEHLGPYRQGEALVVVGYEGLDARVYRLEWD
GEQRLLCPRTTGSWHGRVSGSGDGTRWAGVWSDAEHVPDVWCWRVSNDISLGDTTLQRRTHLHPEIEAKLCPARSIEWTS
DPGVTVQGLLVLPRDGTAKPPYPLVVQIHGGPTSQWANEFVASWHDWAQPLASRGCAVLLPNPRGSTGRGTQWINALFGD
VGGGEYRDVVSGVEALVAAGLADPFRLGVSGWSWGGYLTAWTITQTDRFRAAFMGAGLCNLISDNNLGDIPSANLSYFER
SPSEDPEPYWDRSPIRYVQRVRTPVLIAHGEDDERVSVCESIQFYRALQILEKPCQLVTYPREKHGFEERNHQRDLLTRI
LQWFAQHLDLEAPERVTMATTAPSASG

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=254, Percent_Identity=32.2834645669291, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI18450280, Length=266, Percent_Identity=28.1954887218045, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI37577089, Length=266, Percent_Identity=28.1954887218045, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI16933540, Length=274, Percent_Identity=24.4525547445255, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI194394146, Length=353, Percent_Identity=24.929178470255, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17552908, Length=215, Percent_Identity=32.093023255814, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25149159, Length=262, Percent_Identity=30.5343511450382, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI25144537, Length=356, Percent_Identity=28.0898876404494, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144540, Length=356, Percent_Identity=28.0898876404494, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17564632, Length=267, Percent_Identity=24.7191011235955, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564634, Length=267, Percent_Identity=24.7191011235955, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324793, Length=261, Percent_Identity=25.2873563218391, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551969, Length=321, Percent_Identity=24.9221183800623, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI45550825, Length=321, Percent_Identity=24.9221183800623, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI45553511, Length=321, Percent_Identity=24.9221183800623, Blast_Score=92, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 75238; Mature: 75238

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDSEEVKVSENATTILTVDELVTMQRPFDVEVAPDGETIVYVVRPVSREEEHWRSSLW
CCCCCCCEEECCCCEEEEEHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCHHHHHCCEE
IVPFMEGEARQFTSGLWHDREPRWSPDGGWIAFLSDRAERGKTSVYLIPRNGGEALRVFD
EEEECCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEEC
QAGEIDNLSWSPDGRFLAFLMVEPETEEEKQRRERRDDARVWDADWKYRRLWLLDVRTRA
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEECCCCCEEEEEEEEECHHH
ARVVSPERVQVWAYAWAPDSARLALAVSGTPRVDDVFRVTSVALLDIESGEYRELFTMRG
HHCCCCCEEEEEEEEECCCCCEEEEEECCCCCHHHHHHEEEEEEEEECCCCHHHHHHHHH
VAEDLVWSADGEWLAYRGPLGRVVHGEAVFRRRVRGGEAECLTAGYRGTVEHLGPYRQGE
HHHHHEECCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCEEEECCCCCCHHHCCCCCCCC
ALVVVGYEGLDARVYRLEWDGEQRLLCPRTTGSWHGRVSGSGDGTRWAGVWSDAEHVPDV
EEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCEEECCCCCCCEEEEECCCCCCCCCE
WCWRVSNDISLGDTTLQRRTHLHPEIEAKLCPARSIEWTSDPGVTVQGLLVLPRDGTAKP
EEEEECCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCC
PYPLVVQIHGGPTSQWANEFVASWHDWAQPLASRGCAVLLPNPRGSTGRGTQWINALFGD
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCC
VGGGEYRDVVSGVEALVAAGLADPFRLGVSGWSWGGYLTAWTITQTDRFRAAFMGAGLCN
CCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCHHH
LISDNNLGDIPSANLSYFERSPSEDPEPYWDRSPIRYVQRVRTPVLIAHGEDDERVSVCE
HHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHH
SIQFYRALQILEKPCQLVTYPREKHGFEERNHQRDLLTRILQWFAQHLDLEAPERVTMAT
HHHHHHHHHHHHCCHHEEECCHHHCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
TAPSASG
CCCCCCC
>Mature Secondary Structure
MVLDSEEVKVSENATTILTVDELVTMQRPFDVEVAPDGETIVYVVRPVSREEEHWRSSLW
CCCCCCCEEECCCCEEEEEHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCHHHHHCCEE
IVPFMEGEARQFTSGLWHDREPRWSPDGGWIAFLSDRAERGKTSVYLIPRNGGEALRVFD
EEEECCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEEC
QAGEIDNLSWSPDGRFLAFLMVEPETEEEKQRRERRDDARVWDADWKYRRLWLLDVRTRA
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEECCCCCEEEEEEEEECHHH
ARVVSPERVQVWAYAWAPDSARLALAVSGTPRVDDVFRVTSVALLDIESGEYRELFTMRG
HHCCCCCEEEEEEEEECCCCCEEEEEECCCCCHHHHHHEEEEEEEEECCCCHHHHHHHHH
VAEDLVWSADGEWLAYRGPLGRVVHGEAVFRRRVRGGEAECLTAGYRGTVEHLGPYRQGE
HHHHHEECCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCEEEECCCCCCHHHCCCCCCCC
ALVVVGYEGLDARVYRLEWDGEQRLLCPRTTGSWHGRVSGSGDGTRWAGVWSDAEHVPDV
EEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCEEECCCCCCCEEEEECCCCCCCCCE
WCWRVSNDISLGDTTLQRRTHLHPEIEAKLCPARSIEWTSDPGVTVQGLLVLPRDGTAKP
EEEEECCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCC
PYPLVVQIHGGPTSQWANEFVASWHDWAQPLASRGCAVLLPNPRGSTGRGTQWINALFGD
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCC
VGGGEYRDVVSGVEALVAAGLADPFRLGVSGWSWGGYLTAWTITQTDRFRAAFMGAGLCN
CCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCHHH
LISDNNLGDIPSANLSYFERSPSEDPEPYWDRSPIRYVQRVRTPVLIAHGEDDERVSVCE
HHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHH
SIQFYRALQILEKPCQLVTYPREKHGFEERNHQRDLLTRILQWFAQHLDLEAPERVTMAT
HHHHHHHHHHHHCCHHEEECCHHHCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
TAPSASG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]