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The map label for this gene is cutS [H]

Identifier: 221635971

GI number: 221635971

Start: 559142

End: 559642

Strand: Reverse

Name: cutS [H]

Synonym: trd_A0565

Alternate gene names: 221635971

Gene position: 559642-559142 (Counterclockwise)

Preceding gene: 221635972

Following gene: 221635970

Centisome position: 60.98

GC content: 59.88

Gene sequence:

>501_bases
ATGGAACGTGTGCCGATCACAGTTACCGTCAATGGGCGGACGTACACCGCCGAAGTCGAACCGCGGCTTTTGCTCGTCCA
TTTCATTCGCGATGTCCTCAACCTCACGGGCACGCATATCGGCTGCGACACGACCAGCTGCGGTGCCTGCACGGTCATTT
GGAACGGGCGTCCCGTCAAGTCATGTACGGTCTTCGCCGTACAAGCTGACGGAACCGAGATCCTGACCGTCGAGGGTCTG
GAGCGTGATGGCCAGCTGCACCCGGTCCAAGAAGGCTTTTGGGAAGAGCATGGACTGCAGTGCGGCTACTGCACACCGGG
AATGATGATGACCGCCGTCGCGTTGCTCGCGGAAAATCCTGATCCAACCGAGGAAGAGATCCGGGCGGCGATTTCCGGCA
ATCTCTGCCGCTGTACCGGCTATGTCAACATCGTCAAGGCGATCCAGTACGCAGCACGCAAGATGCGCGAAAGCGCCACA
GCAGGTGTGGGAGGAGCGTGA

Upstream 100 bases:

>100_bases
CCCAGCGGATTACAAACGAGCGGTTGCCCGGACGATGGTGTTCCGTGCCTTGCGTCGAGCGCTCGAGCGAGCACAAGCCA
ACGGATGAGGGAGGCAGAGC

Downstream 100 bases:

>100_bases
ACGATGACAGCGACAGCTGTTCGCGGTATCGGCGTTCCAGTCAAGCGGAAGGAAGATCCGCGGTTCATTCGCGGGAAGGG
AACCTACGTCGACGACGTCA

Product: [2Fe-2S] binding domain protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MERVPITVTVNGRTYTAEVEPRLLLVHFIRDVLNLTGTHIGCDTTSCGACTVIWNGRPVKSCTVFAVQADGTEILTVEGL
ERDGQLHPVQEGFWEEHGLQCGYCTPGMMMTAVALLAENPDPTEEEIRAAISGNLCRCTGYVNIVKAIQYAARKMRESAT
AGVGGA

Sequences:

>Translated_166_residues
MERVPITVTVNGRTYTAEVEPRLLLVHFIRDVLNLTGTHIGCDTTSCGACTVIWNGRPVKSCTVFAVQADGTEILTVEGL
ERDGQLHPVQEGFWEEHGLQCGYCTPGMMMTAVALLAENPDPTEEEIRAAISGNLCRCTGYVNIVKAIQYAARKMRESAT
AGVGGA
>Mature_166_residues
MERVPITVTVNGRTYTAEVEPRLLLVHFIRDVLNLTGTHIGCDTTSCGACTVIWNGRPVKSCTVFAVQADGTEILTVEGL
ERDGQLHPVQEGFWEEHGLQCGYCTPGMMMTAVALLAENPDPTEEEIRAAISGNLCRCTGYVNIVKAIQYAARKMRESAT
AGVGGA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=38.125, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=40.1315789473684, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786480, Length=170, Percent_Identity=42.9411764705882, Blast_Score=141, Evalue=2e-35,
Organism=Escherichia coli, GI1789232, Length=149, Percent_Identity=38.9261744966443, Blast_Score=107, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=40.9090909090909, Blast_Score=129, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=40.9090909090909, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17540638, Length=165, Percent_Identity=43.030303030303, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17737937, Length=161, Percent_Identity=36.6459627329193, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=35.0649350649351, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=35.8024691358025, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=35.8024691358025, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=34.8387096774194, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=34.1614906832298, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17915; Mature: 17915

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVPITVTVNGRTYTAEVEPRLLLVHFIRDVLNLTGTHIGCDTTSCGACTVIWNGRPVK
CCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
SCTVFAVQADGTEILTVEGLERDGQLHPVQEGFWEEHGLQCGYCTPGMMMTAVALLAENP
CEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
DPTEEEIRAAISGNLCRCTGYVNIVKAIQYAARKMRESATAGVGGA
CCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERVPITVTVNGRTYTAEVEPRLLLVHFIRDVLNLTGTHIGCDTTSCGACTVIWNGRPVK
CCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
SCTVFAVQADGTEILTVEGLERDGQLHPVQEGFWEEHGLQCGYCTPGMMMTAVALLAENP
CEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
DPTEEEIRAAISGNLCRCTGYVNIVKAIQYAARKMRESATAGVGGA
CCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]