Click here to switch to the map view.

The map label for this gene is dppE [H]

Identifier: 221635729

GI number: 221635729

Start: 308618

End: 310462

Strand: Reverse

Name: dppE [H]

Synonym: trd_A0323

Alternate gene names: 221635729

Gene position: 310462-308618 (Counterclockwise)

Preceding gene: 221635730

Following gene: 221635726

Centisome position: 33.83

GC content: 61.73

Gene sequence:

>1845_bases
ATGAGCGACAAACTCCGCTGGTGGGAAGATCCTGAGCAAGTCGCCCTCTTGTGGAAACGGTTCCAAGTCGTCGGTATGGA
CCGGCGCGAGTTCATCCGCATAGTGGGCGCAGTCGGCGGAACAACCGGCGCAGCCTTGGCCGCAGCAGCCTGCCAGCGCG
GTCCTGAAGCCACGCCGACCCCTGTCGCAGCCGTCACGCCACCGCCTGTCCCGACTCCCACACCACCGCGCGCAGTCGGC
CCGACCCCGACTGCCGCCCCTGCTCCCACGCCCGCCGAGGGGGAACTCGCCGCGGATCAGGTCTTCCGTACCAACCTCGA
GCGGGACCCGCAGAGCTTCGATTTCAACCGTGATCTCTATTGTGGGGGCGACGAGTCCACCTTCGCCATGCTCGGCATGT
TCACGCCGGACCTCGAGGTGGTTCCCGATATCGCCGAGCGCTGGGAGCCCAACCAGGACGCGTCGGTCTGGACCTTCTAC
ATCCGCAAGGACAGTTACTGGAGCAACGGTGATCCGGTCACTGCCCACGACTACGAGTGGTCCTGGAAGCGTCAGCTCGA
TCCAGCCACCGCCGCCCCCTATGCAGGTTTCCTGTACGACATCAAGAATGCAGAAGCGTTCAATACCCAGAAGCCCGGTG
TGACGCGCGACGACGTCGGCGTCAAAGCGCTCGACGACTACACGCTCCAGGTCACACTGGAGGGGCCACGCGGTTATTTC
CCCATTCTGGCCGCCTATATCGCCGCCGCGCCAGCCCATCGCCCCTCGGTCGAGAAGTACGGCGACAAGTGGACCGAGGC
CGAAAACATCGTCTGCAACGGCCCCTTCAAGCTCGTCCGCTGGGAGCACGACAAGATCGTCGTCTTGGAGAAGAACGAGA
AGTATTGGAACGCCAAGAACATCACGCTCCAGCGGGTCGAGCGCCCGATCATCCCGAGCGAAGCAGTGCTGCAAGCCTAC
GAGAACAACGAGATCGACTGGATGTGGCGCGGACCACTCGGCCAGCTCGAGCGGATCCGCTCCGATCCCAAGCTCAGCAA
GGAGTACCACCAGTTCAACCTCTTCGGGACCTGGTATCTCGTTCCCGATCCGAAGTTCGAGCCCTACAATCTCAAAGAAG
TGCGCCGGGCCATGGCCCATGCTATCGACCGCGAGACGATCGTCAAGCAGGTGCTCAAGGGGCTCGCCACGGTCGCCTAC
ACCTTCACACCGCCTGGTATGCCCTACTACATCGAACCGGACGACAAGATCCGCGAACTCACCGAGTACAACCCGGACAA
GGCGCGCCAGTGGCTCAAGGGTACTCCTTACGAGGGCGGCAAGAACTGGCCGAAGGGTCTCACCCTCACCCACCGCGAGG
AGGGTGACGCTCCAAAGGCCGCTGCTGCTGCCATCATCCAGATGCTCAAGGAAGTGCTCGGTATGGAGCTCGAGCACATC
ATCGGCGAGCCACGCGAGACCTACGAGCGGATGTGGAAGCACGAGATCCCGCTCATGTGGGTCCGTTGGTACGTCGACTA
CCCCGACCCCGCCAACACCCTCTTCCAAGTCTGGTATTCGAAGGCACCGACGGGCCGCCGCCATGAGTGGTCAAACGAGG
AATTCGACCGACTCACGCTCCAGGCGAACGGCGAGCAGGATCCGAAGAAGCGCTACGAGCTGTACTACAAGGCCCAACTG
ATCCAGCTGGAGGAGGCCGCGGCAATCTACGTCTACAACCCCTGGAGCTACGGACTCATGAAGCCATGGGTCACGAATCT
CCCCCGCAATCGCAACGGTGACTTCATGCCAGCTTGGAATATCTTTACTCGAGACTACGACTACTACAAGATTCTCAAGC
ACTGA

Upstream 100 bases:

>100_bases
GACTCGCAAACGCGACTGAAAGGAGGTGTGCACGATCGGAAACCATGGACACTCGTTTCGAGTCGAGGAGTCGTCTCGTG
ATCCAAGAGGAGGAGGTACG

Downstream 100 bases:

>100_bases
TCCGGAACTCGACGAGCGAGCCCGGGGCAGCATTCCCCCGGGCTCGTTCTCTCTCCTCCGCCATCGAATACCTTCACCGG
CTACACCGGATCCAGCGGGG

Product: oligopeptide ABC transporter periplasmic oligopeptide-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 613

Protein sequence:

>614_residues
MSDKLRWWEDPEQVALLWKRFQVVGMDRREFIRIVGAVGGTTGAALAAAACQRGPEATPTPVAAVTPPPVPTPTPPRAVG
PTPTAAPAPTPAEGELAADQVFRTNLERDPQSFDFNRDLYCGGDESTFAMLGMFTPDLEVVPDIAERWEPNQDASVWTFY
IRKDSYWSNGDPVTAHDYEWSWKRQLDPATAAPYAGFLYDIKNAEAFNTQKPGVTRDDVGVKALDDYTLQVTLEGPRGYF
PILAAYIAAAPAHRPSVEKYGDKWTEAENIVCNGPFKLVRWEHDKIVVLEKNEKYWNAKNITLQRVERPIIPSEAVLQAY
ENNEIDWMWRGPLGQLERIRSDPKLSKEYHQFNLFGTWYLVPDPKFEPYNLKEVRRAMAHAIDRETIVKQVLKGLATVAY
TFTPPGMPYYIEPDDKIRELTEYNPDKARQWLKGTPYEGGKNWPKGLTLTHREEGDAPKAAAAAIIQMLKEVLGMELEHI
IGEPRETYERMWKHEIPLMWVRWYVDYPDPANTLFQVWYSKAPTGRRHEWSNEEFDRLTLQANGEQDPKKRYELYYKAQL
IQLEEAAAIYVYNPWSYGLMKPWVTNLPRNRNGDFMPAWNIFTRDYDYYKILKH

Sequences:

>Translated_614_residues
MSDKLRWWEDPEQVALLWKRFQVVGMDRREFIRIVGAVGGTTGAALAAAACQRGPEATPTPVAAVTPPPVPTPTPPRAVG
PTPTAAPAPTPAEGELAADQVFRTNLERDPQSFDFNRDLYCGGDESTFAMLGMFTPDLEVVPDIAERWEPNQDASVWTFY
IRKDSYWSNGDPVTAHDYEWSWKRQLDPATAAPYAGFLYDIKNAEAFNTQKPGVTRDDVGVKALDDYTLQVTLEGPRGYF
PILAAYIAAAPAHRPSVEKYGDKWTEAENIVCNGPFKLVRWEHDKIVVLEKNEKYWNAKNITLQRVERPIIPSEAVLQAY
ENNEIDWMWRGPLGQLERIRSDPKLSKEYHQFNLFGTWYLVPDPKFEPYNLKEVRRAMAHAIDRETIVKQVLKGLATVAY
TFTPPGMPYYIEPDDKIRELTEYNPDKARQWLKGTPYEGGKNWPKGLTLTHREEGDAPKAAAAAIIQMLKEVLGMELEHI
IGEPRETYERMWKHEIPLMWVRWYVDYPDPANTLFQVWYSKAPTGRRHEWSNEEFDRLTLQANGEQDPKKRYELYYKAQL
IQLEEAAAIYVYNPWSYGLMKPWVTNLPRNRNGDFMPAWNIFTRDYDYYKILKH
>Mature_613_residues
SDKLRWWEDPEQVALLWKRFQVVGMDRREFIRIVGAVGGTTGAALAAAACQRGPEATPTPVAAVTPPPVPTPTPPRAVGP
TPTAAPAPTPAEGELAADQVFRTNLERDPQSFDFNRDLYCGGDESTFAMLGMFTPDLEVVPDIAERWEPNQDASVWTFYI
RKDSYWSNGDPVTAHDYEWSWKRQLDPATAAPYAGFLYDIKNAEAFNTQKPGVTRDDVGVKALDDYTLQVTLEGPRGYFP
ILAAYIAAAPAHRPSVEKYGDKWTEAENIVCNGPFKLVRWEHDKIVVLEKNEKYWNAKNITLQRVERPIIPSEAVLQAYE
NNEIDWMWRGPLGQLERIRSDPKLSKEYHQFNLFGTWYLVPDPKFEPYNLKEVRRAMAHAIDRETIVKQVLKGLATVAYT
FTPPGMPYYIEPDDKIRELTEYNPDKARQWLKGTPYEGGKNWPKGLTLTHREEGDAPKAAAAAIIQMLKEVLGMELEHII
GEPRETYERMWKHEIPLMWVRWYVDYPDPANTLFQVWYSKAPTGRRHEWSNEEFDRLTLQANGEQDPKKRYELYYKAQLI
QLEEAAAIYVYNPWSYGLMKPWVTNLPRNRNGDFMPAWNIFTRDYDYYKILKH

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=511, Percent_Identity=30.5283757338552, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI1789397, Length=546, Percent_Identity=30.952380952381, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI87081878, Length=523, Percent_Identity=27.9158699808795, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789966, Length=447, Percent_Identity=24.8322147651007, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787762, Length=446, Percent_Identity=24.2152466367713, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789887, Length=491, Percent_Identity=24.2362525458248, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787551, Length=447, Percent_Identity=23.2662192393736, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787052, Length=501, Percent_Identity=21.5568862275449, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 70750; Mature: 70618

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKLRWWEDPEQVALLWKRFQVVGMDRREFIRIVGAVGGTTGAALAAAACQRGPEATPT
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
PVAAVTPPPVPTPTPPRAVGPTPTAAPAPTPAEGELAADQVFRTNLERDPQSFDFNRDLY
CEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEE
CGGDESTFAMLGMFTPDLEVVPDIAERWEPNQDASVWTFYIRKDSYWSNGDPVTAHDYEW
ECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCEEECCCCC
SWKRQLDPATAAPYAGFLYDIKNAEAFNTQKPGVTRDDVGVKALDDYTLQVTLEGPRGYF
CHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEEECCCCHH
PILAAYIAAAPAHRPSVEKYGDKWTEAENIVCNGPFKLVRWEHDKIVVLEKNEKYWNAKN
HHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEECCCEEEEEECCCEEEEEECCCCEECCCC
ITLQRVERPIIPSEAVLQAYENNEIDWMWRGPLGQLERIRSDPKLSKEYHQFNLFGTWYL
CCHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCHHHHHHEEEEEEEEEE
VPDPKFEPYNLKEVRRAMAHAIDRETIVKQVLKGLATVAYTFTPPGMPYYIEPDDKIREL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEECCCHHHHHH
TEYNPDKARQWLKGTPYEGGKNWPKGLTLTHREEGDAPKAAAAAIIQMLKEVLGMELEHI
HHCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHH
IGEPRETYERMWKHEIPLMWVRWYVDYPDPANTLFQVWYSKAPTGRRHEWSNEEFDRLTL
HCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
QANGEQDPKKRYELYYKAQLIQLEEAAAIYVYNPWSYGLMKPWVTNLPRNRNGDFMPAWN
EECCCCCHHHHHHHHHHHEEEEEECCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCEECC
IFTRDYDYYKILKH
CEECCCCHHHHHCC
>Mature Secondary Structure 
SDKLRWWEDPEQVALLWKRFQVVGMDRREFIRIVGAVGGTTGAALAAAACQRGPEATPT
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
PVAAVTPPPVPTPTPPRAVGPTPTAAPAPTPAEGELAADQVFRTNLERDPQSFDFNRDLY
CEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEE
CGGDESTFAMLGMFTPDLEVVPDIAERWEPNQDASVWTFYIRKDSYWSNGDPVTAHDYEW
ECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCEEECCCCC
SWKRQLDPATAAPYAGFLYDIKNAEAFNTQKPGVTRDDVGVKALDDYTLQVTLEGPRGYF
CHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEEECCCCHH
PILAAYIAAAPAHRPSVEKYGDKWTEAENIVCNGPFKLVRWEHDKIVVLEKNEKYWNAKN
HHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEECCCEEEEEECCCEEEEEECCCCEECCCC
ITLQRVERPIIPSEAVLQAYENNEIDWMWRGPLGQLERIRSDPKLSKEYHQFNLFGTWYL
CCHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCHHHHHHEEEEEEEEEE
VPDPKFEPYNLKEVRRAMAHAIDRETIVKQVLKGLATVAYTFTPPGMPYYIEPDDKIREL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEECCCHHHHHH
TEYNPDKARQWLKGTPYEGGKNWPKGLTLTHREEGDAPKAAAAAIIQMLKEVLGMELEHI
HHCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHH
IGEPRETYERMWKHEIPLMWVRWYVDYPDPANTLFQVWYSKAPTGRRHEWSNEEFDRLTL
HCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
QANGEQDPKKRYELYYKAQLIQLEEAAAIYVYNPWSYGLMKPWVTNLPRNRNGDFMPAWN
EECCCCCHHHHHHHHHHHEEEEEECCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCEECC
IFTRDYDYYKILKH
CEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]