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The map label for this gene is hypB [H]

Identifier: 221633843

GI number: 221633843

Start: 1880864

End: 1881586

Strand: Reverse

Name: hypB [H]

Synonym: trd_1870

Alternate gene names: 221633843

Gene position: 1881586-1880864 (Counterclockwise)

Preceding gene: 221633844

Following gene: 221633842

Centisome position: 93.94

GC content: 63.9

Gene sequence:

>723_bases
GTGGATGAACGCCTGATTCGCTTCGAGCAACGGCTTCTCGCCCGCAACGACGCGCAGGCTTCGGAGTTGCGCTGGCGGTT
CCTCCGAGCTGGCACCTTCGTGGTCAACCTCGCGTCGAGTCCGGGTGCTGGAAAGACGACGCTTCTCGAAGCGACCGTGC
AGGCACTCGGCGGAGGAAGCCACGTCGGAGTCATCGTCGGTGACCTCGCGACGGACAACGATGCGCGGCGTCTCGCCCAG
GCAGGTGGGCGTGTCCGCCAGATCACGACCGGCACAACGTGCCATCTTGAGGCAGCGATGATCCAGGCAGCGCTCGACGG
TTGGAACCTCGATGAGCTCGAGTACCTGTTCATCGAGAATGTGGGCAATCTCGTTTGCCCCGCAGCGTTCGATCTCGGGG
AAGCGGCTCGAGTCGTCCTTTTCGCCGTGACTGAGGGAGAAGACAAACCGGAAAAGTATCCGCCCCTCGTCCACCAGGCT
GACCTCATCCTGCTGACGAAGTGGGACTTGGCACCGCTCCTCGCCTTCGACGAGGAGCGCTTCACGGAGGCAGTGCGACG
GGTGAATGCGCGAGTAGCGATCCTCACGGTGTCGGCACGCACCGGGGTCGGCCTCGGGGCCTGGTTGGACTGGCTCCAGC
AGCAGCGAGCGCTTCAGTTGACGCAGTGGGGAGCGAAGAAGGGAGCTGACCGTGTGTCTCGCGATTCCGGGGCAGGTGAT
TGA

Upstream 100 bases:

>100_bases
TGGATAAGCTGGCTACCACCTGCCTGCCCAGCGTGCGGCGCAGCAGCCCTGACGGTCGTAGGAGGCCGGGAGCTCGAGCT
GGTCGCTGCGGAGGTGCGTC

Downstream 100 bases:

>100_bases
CCTCGATACGGACTCGCGTGTCGCGCTCGTGAACGTGCTCGGGGTCCGGCGGCGGATCAACGTCGAACTCGTGTGGGACG
ACGGCCTGCAAGCTGGGGAT

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDERLIRFEQRLLARNDAQASELRWRFLRAGTFVVNLASSPGAGKTTLLEATVQALGGGSHVGVIVGDLATDNDARRLAQ
AGGRVRQITTGTTCHLEAAMIQAALDGWNLDELEYLFIENVGNLVCPAAFDLGEAARVVLFAVTEGEDKPEKYPPLVHQA
DLILLTKWDLAPLLAFDEERFTEAVRRVNARVAILTVSARTGVGLGAWLDWLQQQRALQLTQWGAKKGADRVSRDSGAGD

Sequences:

>Translated_240_residues
MDERLIRFEQRLLARNDAQASELRWRFLRAGTFVVNLASSPGAGKTTLLEATVQALGGGSHVGVIVGDLATDNDARRLAQ
AGGRVRQITTGTTCHLEAAMIQAALDGWNLDELEYLFIENVGNLVCPAAFDLGEAARVVLFAVTEGEDKPEKYPPLVHQA
DLILLTKWDLAPLLAFDEERFTEAVRRVNARVAILTVSARTGVGLGAWLDWLQQQRALQLTQWGAKKGADRVSRDSGAGD
>Mature_240_residues
MDERLIRFEQRLLARNDAQASELRWRFLRAGTFVVNLASSPGAGKTTLLEATVQALGGGSHVGVIVGDLATDNDARRLAQ
AGGRVRQITTGTTCHLEAAMIQAALDGWNLDELEYLFIENVGNLVCPAAFDLGEAARVVLFAVTEGEDKPEKYPPLVHQA
DLILLTKWDLAPLLAFDEERFTEAVRRVNARVAILTVSARTGVGLGAWLDWLQQQRALQLTQWGAKKGADRVSRDSGAGD

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=214, Percent_Identity=47.196261682243, Blast_Score=191, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 26133; Mature: 26133

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00036 BZIP_BASIC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERLIRFEQRLLARNDAQASELRWRFLRAGTFVVNLASSPGAGKTTLLEATVQALGGGS
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC
HVGVIVGDLATDNDARRLAQAGGRVRQITTGTTCHLEAAMIQAALDGWNLDELEYLFIEN
EEEEEEECCCCCHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHHCCCCCCHHHHHEECC
VGNLVCPAAFDLGEAARVVLFAVTEGEDKPEKYPPLVHQADLILLTKWDLAPLLAFDEER
CCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHH
FTEAVRRVNARVAILTVSARTGVGLGAWLDWLQQQRALQLTQWGAKKGADRVSRDSGAGD
HHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MDERLIRFEQRLLARNDAQASELRWRFLRAGTFVVNLASSPGAGKTTLLEATVQALGGGS
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC
HVGVIVGDLATDNDARRLAQAGGRVRQITTGTTCHLEAAMIQAALDGWNLDELEYLFIEN
EEEEEEECCCCCHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHHCCCCCCHHHHHEECC
VGNLVCPAAFDLGEAARVVLFAVTEGEDKPEKYPPLVHQADLILLTKWDLAPLLAFDEER
CCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHH
FTEAVRRVNARVAILTVSARTGVGLGAWLDWLQQQRALQLTQWGAKKGADRVSRDSGAGD
HHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]