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The map label for this gene is hypA

Identifier: 221633844

GI number: 221633844

Start: 1881579

End: 1881974

Strand: Reverse

Name: hypA

Synonym: trd_1871

Alternate gene names: 221633844

Gene position: 1881974-1881579 (Counterclockwise)

Preceding gene: 221633845

Following gene: 221633843

Centisome position: 93.96

GC content: 63.13

Gene sequence:

>396_bases
ATGCACGAACTCTCTGTCGCACTCAGCCTGATCGATGCGCTGACCGAATCCTTGGGTACGCATCCTGACGTGCGGATAGA
GGTCATCCACCTGAAGATCGGTCCTCTTTCTGGCGTGATCGAGCCAGCGCTTCGGTCAGCCTTCGAGATCGCGGCGGTCG
GCACGATAGCGGAAGGTGCGATCCTCGCTATCCAGGTCCCGCCGATCGTCCTCCGCTGTGAGGAGTGCGGCCAGGAGACG
AACTTGAGCGGTGCAGATGTCATGGACAACCGAGATGGCCTCGGCTCCTGGATAAGCTGGCTACCACCTGCCTGCCCAGC
GTGCGGCGCAGCAGCCCTGACGGTCGTAGGAGGCCGGGAGCTCGAGCTGGTCGCTGCGGAGGTGCGTCGTGGATGA

Upstream 100 bases:

>100_bases
GCTGGGGAAGCAGAGCTGGCTGCTCGGGCTGGCGGGTGACCTGGCCAAGGATGCGCTGCTGCGCATACTCACGCCTCGGC
GGTGAGGACGGAAAGGAAGG

Downstream 100 bases:

>100_bases
ACGCCTGATTCGCTTCGAGCAACGGCTTCTCGCCCGCAACGACGCGCAGGCTTCGGAGTTGCGCTGGCGGTTCCTCCGAG
CTGGCACCTTCGTGGTCAAC

Product: putative hydrogenase nickel incorporation protein hypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MHELSVALSLIDALTESLGTHPDVRIEVIHLKIGPLSGVIEPALRSAFEIAAVGTIAEGAILAIQVPPIVLRCEECGQET
NLSGADVMDNRDGLGSWISWLPPACPACGAAALTVVGGRELELVAAEVRRG

Sequences:

>Translated_131_residues
MHELSVALSLIDALTESLGTHPDVRIEVIHLKIGPLSGVIEPALRSAFEIAAVGTIAEGAILAIQVPPIVLRCEECGQET
NLSGADVMDNRDGLGSWISWLPPACPACGAAALTVVGGRELELVAAEVRRG
>Mature_131_residues
MHELSVALSLIDALTESLGTHPDVRIEVIHLKIGPLSGVIEPALRSAFEIAAVGTIAEGAILAIQVPPIVLRCEECGQET
NLSGADVMDNRDGLGSWISWLPPACPACGAAALTVVGGRELELVAAEVRRG

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_THERP (B9L1X1)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002523070.1
- GeneID:   7356306
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_1871
- OMA:   PVELEVW
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 13629; Mature: 13629

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSVALSLIDALTESLGTHPDVRIEVIHLKIGPLSGVIEPALRSAFEIAAVGTIAEGA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCE
ILAIQVPPIVLRCEECGQETNLSGADVMDNRDGLGSWISWLPPACPACGAAALTVVGGRE
EEEEECCCEEEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCC
LELVAAEVRRG
CEEEHHHHCCC
>Mature Secondary Structure
MHELSVALSLIDALTESLGTHPDVRIEVIHLKIGPLSGVIEPALRSAFEIAAVGTIAEGA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCE
ILAIQVPPIVLRCEECGQETNLSGADVMDNRDGLGSWISWLPPACPACGAAALTVVGGRE
EEEEECCCEEEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCC
LELVAAEVRRG
CEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA