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The map label for this gene is hypE [H]

Identifier: 221633839

GI number: 221633839

Start: 1878225

End: 1879265

Strand: Reverse

Name: hypE [H]

Synonym: trd_1866

Alternate gene names: 221633839

Gene position: 1879265-1878225 (Counterclockwise)

Preceding gene: 221633840

Following gene: 221633838

Centisome position: 93.82

GC content: 65.8

Gene sequence:

>1041_bases
ATGCGTGCGACGATCGTCGGTCTTCCCTTTCACGACTCGACCATCGAGCTTGCCCATGGAGCAGGTGGCAAGGCAAGCCG
ACGGCTCATCGAGGGACTTTTCCTGCCGCTGCTCATGAATCCGATGCTCGCCGAGTTGCATGATGCCGCCCTGCTCGCGA
CCGGCCACGGTACACTGGCGCTGACGACGGATGCCTTCGTGGTGCGCCCCCTCCGCTTTCCCGGCGGCTCCATCGGTGAG
CTCGCGGTTAACGGAACGATCAATGACCTCGCGGTCAGCGGCGCCCGCCCGCTCGCCCTGGCAGCTGCGTTCATCGTGGA
GGCTGGACTCTCTAGCGACGTTCTCCGTGCTGAGGTCGAGGCACTGGCGGCAGCAGCAGCGCGTGCCGGAGTTCCGGTGG
TGACCGGCGATACCAAGGTCGTGGAGCACGGCAAGGCTGATGGGCTGTACATCGTCACCACTGGCCTCGGGTTCGTCGAT
CCCCGGCTCCGCCTCGGATCGGGCTTCGTCCAACCCGGCGACCGGGTGCTCGTCTCCGGCCCCATTGGGGATCACGGCAT
CACGGTGCTCCTGGCTCGCGGGGAGCTGGATCTGGAGGCTGATCTAGTCTCCGATACGCGCCCCCTCACACCATTCGTCG
ATGCGCTCACCGCCACAGCGGCTCCTGGTCTCCGCTGGATGCGCGATCCCACACGAGGCGGCGTGGCAACAGCCCTCAAT
GAGCTGGCGCGCGACACTGGTTTGGCGGTCGTTCTCGAGGAAGAAGCTATACCTGTCCGTGATGCAGTCCGTGGTGCCTG
CGAAGTCCTCGGACTCGACCCCCTCCATATCGCCAACGAGGGGCAGCTCCTGGTGGTCGTGGCACCAGAGTGGGCCGACG
CAGCGCTCGCCGCGCTGCGCAGCGTACCTGGAGGTCAGGATGCTGCCTGCATCGGAACCATCGAGACACACCCACCGGGT
GTCGTCACCGTAACCACTGCTTACGGAGGCCGGCGCGTCGTTGACATGCTGGTCGGTGACCCACTGCCACGCATCTGCTA
G

Upstream 100 bases:

>100_bases
CAGAGCATCCTATCGGTGCCCTGATGGTCTCCAACGAGGGCGCGTGTGCAGCCTACTATCACTACGTCCACCGGCTCTCG
GCGACGAGGAGTGCGTAGCG

Downstream 100 bases:

>100_bases
TTCGCAGCGCTCCTGAGGAGGGACGCGATGGGCCAGCCGCTCTCGAGGTTCGTCCATGACCGGCTGCTCGAGCGGAATAC
GCTCTCGCGTGCGTTCTTTC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRATIVGLPFHDSTIELAHGAGGKASRRLIEGLFLPLLMNPMLAELHDAALLATGHGTLALTTDAFVVRPLRFPGGSIGE
LAVNGTINDLAVSGARPLALAAAFIVEAGLSSDVLRAEVEALAAAAARAGVPVVTGDTKVVEHGKADGLYIVTTGLGFVD
PRLRLGSGFVQPGDRVLVSGPIGDHGITVLLARGELDLEADLVSDTRPLTPFVDALTATAAPGLRWMRDPTRGGVATALN
ELARDTGLAVVLEEEAIPVRDAVRGACEVLGLDPLHIANEGQLLVVVAPEWADAALAALRSVPGGQDAACIGTIETHPPG
VVTVTTAYGGRRVVDMLVGDPLPRIC

Sequences:

>Translated_346_residues
MRATIVGLPFHDSTIELAHGAGGKASRRLIEGLFLPLLMNPMLAELHDAALLATGHGTLALTTDAFVVRPLRFPGGSIGE
LAVNGTINDLAVSGARPLALAAAFIVEAGLSSDVLRAEVEALAAAAARAGVPVVTGDTKVVEHGKADGLYIVTTGLGFVD
PRLRLGSGFVQPGDRVLVSGPIGDHGITVLLARGELDLEADLVSDTRPLTPFVDALTATAAPGLRWMRDPTRGGVATALN
ELARDTGLAVVLEEEAIPVRDAVRGACEVLGLDPLHIANEGQLLVVVAPEWADAALAALRSVPGGQDAACIGTIETHPPG
VVTVTTAYGGRRVVDMLVGDPLPRIC
>Mature_346_residues
MRATIVGLPFHDSTIELAHGAGGKASRRLIEGLFLPLLMNPMLAELHDAALLATGHGTLALTTDAFVVRPLRFPGGSIGE
LAVNGTINDLAVSGARPLALAAAFIVEAGLSSDVLRAEVEALAAAAARAGVPVVTGDTKVVEHGKADGLYIVTTGLGFVD
PRLRLGSGFVQPGDRVLVSGPIGDHGITVLLARGELDLEADLVSDTRPLTPFVDALTATAAPGLRWMRDPTRGGVATALN
ELARDTGLAVVLEEEAIPVRDAVRGACEVLGLDPLHIANEGQLLVVVAPEWADAALAALRSVPGGQDAACIGTIETHPPG
VVTVTTAYGGRRVVDMLVGDPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=340, Percent_Identity=46.1764705882353, Blast_Score=274, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35585; Mature: 35585

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATIVGLPFHDSTIELAHGAGGKASRRLIEGLFLPLLMNPMLAELHDAALLATGHGTLA
CCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEE
LTTDAFVVRPLRFPGGSIGELAVNGTINDLAVSGARPLALAAAFIVEAGLSSDVLRAEVE
EEECEEEEEEEECCCCCCCCEEECCCHHHHEECCCCHHHHHHHHHHHCCCCHHHHHHHHH
ALAAAAARAGVPVVTGDTKVVEHGKADGLYIVTTGLGFVDPRLRLGSGFVQPGDRVLVSG
HHHHHHHHCCCEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEC
PIGDHGITVLLARGELDLEADLVSDTRPLTPFVDALTATAAPGLRWMRDPTRGGVATALN
CCCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
ELARDTGLAVVLEEEAIPVRDAVRGACEVLGLDPLHIANEGQLLVVVAPEWADAALAALR
HHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCHHHHHHHHH
SVPGGQDAACIGTIETHPPGVVTVTTAYGGRRVVDMLVGDPLPRIC
CCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEHHHHHCCCCCCCC
>Mature Secondary Structure
MRATIVGLPFHDSTIELAHGAGGKASRRLIEGLFLPLLMNPMLAELHDAALLATGHGTLA
CCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEE
LTTDAFVVRPLRFPGGSIGELAVNGTINDLAVSGARPLALAAAFIVEAGLSSDVLRAEVE
EEECEEEEEEEECCCCCCCCEEECCCHHHHEECCCCHHHHHHHHHHHCCCCHHHHHHHHH
ALAAAAARAGVPVVTGDTKVVEHGKADGLYIVTTGLGFVDPRLRLGSGFVQPGDRVLVSG
HHHHHHHHCCCEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEC
PIGDHGITVLLARGELDLEADLVSDTRPLTPFVDALTATAAPGLRWMRDPTRGGVATALN
CCCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
ELARDTGLAVVLEEEAIPVRDAVRGACEVLGLDPLHIANEGQLLVVVAPEWADAALAALR
HHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCHHHHHHHHH
SVPGGQDAACIGTIETHPPGVVTVTTAYGGRRVVDMLVGDPLPRIC
CCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]