| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is gmhA [H]
Identifier: 221633838
GI number: 221633838
Start: 1877010
End: 1878197
Strand: Reverse
Name: gmhA [H]
Synonym: trd_1865
Alternate gene names: 221633838
Gene position: 1878197-1877010 (Counterclockwise)
Preceding gene: 221633839
Following gene: 221633837
Centisome position: 93.77
GC content: 64.48
Gene sequence:
>1188_bases ATGGGCCAGCCGCTCTCGAGGTTCGTCCATGACCGGCTGCTCGAGCGGAATACGCTCTCGCGTGCGTTCTTTCCGTGCGA GGCTGAGCGCCTCGCAGCGATTTGCCGCGAGATGGCAGAGCGGTTTCTCGCCGGCGGACGCCTGCTCGCGTTCGGTCGAG GTCCGTATGCAACCGACGCGCAACACGTGTCGGTCGAGTTCATCCACCCAGTCATCGTCGGCAAGCGCGCCTTGCCAGCG CTGGACCTGAGCCTCTCCTTCGCCGAATGGAGTACAGCGATCCTACAACCGCAGGACATCGTCATGGGGTTCGGCTCCCC GGAAGGAGATCCGCTTGTTCAGCGCATTTTGGCCGTTTTGCGTTCCCGCGGCGCACTGACCCTCGCCCTTCCCGGAAAAG GAGAGAGCGCGGACTATGCGGTCGAGACCCCGACCGCTGACCCGTTCATTCACCAGGAACTCCTCGAGGTGCTCTACCAC ACCCTGTGGGAGACGGTGCACGTCTTCTTCGAGCACCGGCAGCTTGCGGGGTACGAGGTCGGTGAACTGGCGGCGTTTTA CCCGTTCCTCGGTGGAACGCCAGTCGACCTGCGAGCGGTCGAGCCGGAGGTCGCAGGCTCGATCATAGCCAAGGCGGAGG AGGTTGAGCGATTGCGCGCGGAACTCGCCAGGGAACAGGCCGGAGTGATCGCCGATACGGCGGTCGCGATCGCCCAACGC CTGGAGCGGGGCGGCAAGCTGATCTGCCTCGGGAATGGTGGCTCGGCGACCGACGCCAATGACCTGGCCGTGGACTGCGT CATGCCGCCGGCAGGATACCACTCTCTCCCGGCCATCTCGCTGGCTCTCGAGCCAGCCAACTTGACAGCGATTGCCAACG ATGTGGGCCAGGAGGTGATGTTCCTGCGCCAGCTGATTCCGCATGCGCAGGCTCACGACGTGGTGATCGGCTTCTCGACC AGTGGAGGATCGACGAACGTGATCATGGCGCTGGAGGAGGCCCGGAAGCGAGGTCTCTTGACGGTCGGCTTGCTCGGCTA CGACGGCGGCGAGATTCTGCGGCGGCAGCTCGTCGACCACGCGATCGTCGTTCATTGCGACTACATTCCGCGCATCCAGG AAGCCCAGGCCTCGGCGTACCATGTTCTGCGCGAGGCGTTGGAGGTCACGCTCTATGGGACGGCTTGA
Upstream 100 bases:
>100_bases CGTAACCACTGCTTACGGAGGCCGGCGCGTCGTTGACATGCTGGTCGGTGACCCACTGCCACGCATCTGCTAGTTCGCAG CGCTCCTGAGGAGGGACGCG
Downstream 100 bases:
>100_bases GCTATACGGAACGCGCTGGTGTCCGTACACTGCCGAATTACGGTCGTCACTGGAGTGGCGAGGAGTCGCGTTCATCGAAT ACGACGTCGATGCCGACGTC
Product: phosphoheptose isomerase
Products: NA
Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]
Number of amino acids: Translated: 395; Mature: 394
Protein sequence:
>395_residues MGQPLSRFVHDRLLERNTLSRAFFPCEAERLAAICREMAERFLAGGRLLAFGRGPYATDAQHVSVEFIHPVIVGKRALPA LDLSLSFAEWSTAILQPQDIVMGFGSPEGDPLVQRILAVLRSRGALTLALPGKGESADYAVETPTADPFIHQELLEVLYH TLWETVHVFFEHRQLAGYEVGELAAFYPFLGGTPVDLRAVEPEVAGSIIAKAEEVERLRAELAREQAGVIADTAVAIAQR LERGGKLICLGNGGSATDANDLAVDCVMPPAGYHSLPAISLALEPANLTAIANDVGQEVMFLRQLIPHAQAHDVVIGFST SGGSTNVIMALEEARKRGLLTVGLLGYDGGEILRRQLVDHAIVVHCDYIPRIQEAQASAYHVLREALEVTLYGTA
Sequences:
>Translated_395_residues MGQPLSRFVHDRLLERNTLSRAFFPCEAERLAAICREMAERFLAGGRLLAFGRGPYATDAQHVSVEFIHPVIVGKRALPA LDLSLSFAEWSTAILQPQDIVMGFGSPEGDPLVQRILAVLRSRGALTLALPGKGESADYAVETPTADPFIHQELLEVLYH TLWETVHVFFEHRQLAGYEVGELAAFYPFLGGTPVDLRAVEPEVAGSIIAKAEEVERLRAELAREQAGVIADTAVAIAQR LERGGKLICLGNGGSATDANDLAVDCVMPPAGYHSLPAISLALEPANLTAIANDVGQEVMFLRQLIPHAQAHDVVIGFST SGGSTNVIMALEEARKRGLLTVGLLGYDGGEILRRQLVDHAIVVHCDYIPRIQEAQASAYHVLREALEVTLYGTA >Mature_394_residues GQPLSRFVHDRLLERNTLSRAFFPCEAERLAAICREMAERFLAGGRLLAFGRGPYATDAQHVSVEFIHPVIVGKRALPAL DLSLSFAEWSTAILQPQDIVMGFGSPEGDPLVQRILAVLRSRGALTLALPGKGESADYAVETPTADPFIHQELLEVLYHT LWETVHVFFEHRQLAGYEVGELAAFYPFLGGTPVDLRAVEPEVAGSIIAKAEEVERLRAELAREQAGVIADTAVAIAQRL ERGGKLICLGNGGSATDANDLAVDCVMPPAGYHSLPAISLALEPANLTAIANDVGQEVMFLRQLIPHAQAHDVVIGFSTS GGSTNVIMALEEARKRGLLTVGLLGYDGGEILRRQLVDHAIVVHCDYIPRIQEAQASAYHVLREALEVTLYGTA
Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]
COG id: COG0279
COG function: function code G; Phosphoheptose isomerase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 SIS domain [H]
Homologues:
Organism=Escherichia coli, GI1789539, Length=188, Percent_Identity=34.0425531914894, Blast_Score=84, Evalue=2e-17, Organism=Escherichia coli, GI1786416, Length=175, Percent_Identity=32.5714285714286, Blast_Score=79, Evalue=6e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004515 - InterPro: IPR020620 - InterPro: IPR001347 [H]
Pfam domain/function: PF01380 SIS [H]
EC number: =5.3.1.28 [H]
Molecular weight: Translated: 42740; Mature: 42608
Theoretical pI: Translated: 5.04; Mature: 5.04
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGQPLSRFVHDRLLERNTLSRAFFPCEAERLAAICREMAERFLAGGRLLAFGRGPYATDA CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC QHVSVEFIHPVIVGKRALPALDLSLSFAEWSTAILQPQDIVMGFGSPEGDPLVQRILAVL CCEEHEEHHHHHHCCCCCCEECCEEEHHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHHH RSRGALTLALPGKGESADYAVETPTADPFIHQELLEVLYHTLWETVHVFFEHRQLAGYEV HCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH GELAAFYPFLGGTPVDLRAVEPEVAGSIIAKAEEVERLRAELAREQAGVIADTAVAIAQR HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH LERGGKLICLGNGGSATDANDLAVDCVMPPAGYHSLPAISLALEPANLTAIANDVGQEVM HHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH FLRQLIPHAQAHDVVIGFSTSGGSTNVIMALEEARKRGLLTVGLLGYDGGEILRRQLVDH HHHHHCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHCCCEEEEEEECCHHHHHHHHHHHH AIVVHCDYIPRIQEAQASAYHVLREALEVTLYGTA EEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEECC >Mature Secondary Structure GQPLSRFVHDRLLERNTLSRAFFPCEAERLAAICREMAERFLAGGRLLAFGRGPYATDA CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC QHVSVEFIHPVIVGKRALPALDLSLSFAEWSTAILQPQDIVMGFGSPEGDPLVQRILAVL CCEEHEEHHHHHHCCCCCCEECCEEEHHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHHH RSRGALTLALPGKGESADYAVETPTADPFIHQELLEVLYHTLWETVHVFFEHRQLAGYEV HCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH GELAAFYPFLGGTPVDLRAVEPEVAGSIIAKAEEVERLRAELAREQAGVIADTAVAIAQR HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH LERGGKLICLGNGGSATDANDLAVDCVMPPAGYHSLPAISLALEPANLTAIANDVGQEVM HHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH FLRQLIPHAQAHDVVIGFSTSGGSTNVIMALEEARKRGLLTVGLLGYDGGEILRRQLVDH HHHHHCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHCCCEEEEEEECCHHHHHHHHHHHH AIVVHCDYIPRIQEAQASAYHVLREALEVTLYGTA EEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA