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The map label for this gene is hypD [H]

Identifier: 221633840

GI number: 221633840

Start: 1879268

End: 1880383

Strand: Reverse

Name: hypD [H]

Synonym: trd_1867

Alternate gene names: 221633840

Gene position: 1880383-1879268 (Counterclockwise)

Preceding gene: 221633841

Following gene: 221633839

Centisome position: 93.88

GC content: 62.9

Gene sequence:

>1116_bases
ATGCGATACGTTGACGAACTCCGCGACCCAAAGCTCATCCGAGCAGTGGCAGCAGAGATTTGGCGGGCGGTCGACCCAGA
GCGGCACTATCGGATCATGGAAGTCTGCGGCGGGCATACCCACGCGATTTATCGCCACGGCCTGCCTGAGCTTCTTCCGC
CTATGATCGAGCTGGTGCACGGGCCCGGTTGCCCAGTCTGCGTGTTGCCGATGGGCCGGATCGACGATGGCCTGGCGCTG
GCTGAGCAGCCGAACGTGATCTTCGCCGCCTTCGGCGACATGATGCGCGTGCCCGGACGCAAGGGAACACCGCTCGAGTA
CCAGGCCCGTGGCGCGGATGTCCGCATGGTCTACTCCCCGCTGGATGCCTTGAAGCTCGCCCAGGCCAATCCGCAAAAGC
ACGTGGTCTTCTTTGCGATCGGCTTCGAGACCACAGCACCATCGACGGCACTCACGCTCATGCGCGCCAAGCAGCTGGGG
ATCCGGAACTTCTCGGTGTTCTGTAACCACGTTCTCATCGTCCCTGCCATCCGCGCGATTCTCGATTCCCCCGATATGCG
CTTGGACGGGTTCATCGGTCCAGGACACGTCTCCACCGTGATCGGCTGTCGCCCGTACCTGTTCGTGGCGCGCGACTACG
GGAAACCCTTAGTCGTCTCCGGCTTCGAGCCGCTCGACCTCCTCCAGGCGATCCTCATGATCTTGCGCCAGCTGCGAGAA
GGGCGAGCCGAAGTCGAAAACCAGTACCGGCGCGTCGTCCCCTGGAACGGGAACCCAGCAGCACTCAAGGCGATGGCTGA
AGTCTTCGAGCTCCGACCGTACTTCGAGTGGCGCGGGCTGGGCTTCATCTCGCAATCAGCCTTCAAGATCGCACCAGCCT
ACGCCGACTGGGACGCAGAGGTGCGGTTCGACATCCCCGGGATCCGGGTTACCGATCCCAAGGCAGCCCAGTGCGGTGAG
GTGCTCAAAGGGGTGCTGAAGCCGCCACAATGCAAGCTGTTCGGTCGAGAGTGCACTCCAGAGCATCCTATCGGTGCCCT
GATGGTCTCCAACGAGGGCGCGTGTGCAGCCTACTATCACTACGTCCACCGGCTCTCGGCGACGAGGAGTGCGTAG

Upstream 100 bases:

>100_bases
CAGAGAGCGATCGTTGCTCTCGACTTCGTCCCCGATGTGATGCCAGGGGACGTGCTGCTCGTGCACCTCGGAGTCGCACT
CGTGCGCGTTGGAGGCGATG

Downstream 100 bases:

>100_bases
CGATGCGTGCGACGATCGTCGGTCTTCCCTTTCACGACTCGACCATCGAGCTTGCCCATGGAGCAGGTGGCAAGGCAAGC
CGACGGCTCATCGAGGGACT

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRYVDELRDPKLIRAVAAEIWRAVDPERHYRIMEVCGGHTHAIYRHGLPELLPPMIELVHGPGCPVCVLPMGRIDDGLAL
AEQPNVIFAAFGDMMRVPGRKGTPLEYQARGADVRMVYSPLDALKLAQANPQKHVVFFAIGFETTAPSTALTLMRAKQLG
IRNFSVFCNHVLIVPAIRAILDSPDMRLDGFIGPGHVSTVIGCRPYLFVARDYGKPLVVSGFEPLDLLQAILMILRQLRE
GRAEVENQYRRVVPWNGNPAALKAMAEVFELRPYFEWRGLGFISQSAFKIAPAYADWDAEVRFDIPGIRVTDPKAAQCGE
VLKGVLKPPQCKLFGRECTPEHPIGALMVSNEGACAAYYHYVHRLSATRSA

Sequences:

>Translated_371_residues
MRYVDELRDPKLIRAVAAEIWRAVDPERHYRIMEVCGGHTHAIYRHGLPELLPPMIELVHGPGCPVCVLPMGRIDDGLAL
AEQPNVIFAAFGDMMRVPGRKGTPLEYQARGADVRMVYSPLDALKLAQANPQKHVVFFAIGFETTAPSTALTLMRAKQLG
IRNFSVFCNHVLIVPAIRAILDSPDMRLDGFIGPGHVSTVIGCRPYLFVARDYGKPLVVSGFEPLDLLQAILMILRQLRE
GRAEVENQYRRVVPWNGNPAALKAMAEVFELRPYFEWRGLGFISQSAFKIAPAYADWDAEVRFDIPGIRVTDPKAAQCGE
VLKGVLKPPQCKLFGRECTPEHPIGALMVSNEGACAAYYHYVHRLSATRSA
>Mature_371_residues
MRYVDELRDPKLIRAVAAEIWRAVDPERHYRIMEVCGGHTHAIYRHGLPELLPPMIELVHGPGCPVCVLPMGRIDDGLAL
AEQPNVIFAAFGDMMRVPGRKGTPLEYQARGADVRMVYSPLDALKLAQANPQKHVVFFAIGFETTAPSTALTLMRAKQLG
IRNFSVFCNHVLIVPAIRAILDSPDMRLDGFIGPGHVSTVIGCRPYLFVARDYGKPLVVSGFEPLDLLQAILMILRQLRE
GRAEVENQYRRVVPWNGNPAALKAMAEVFELRPYFEWRGLGFISQSAFKIAPAYADWDAEVRFDIPGIRVTDPKAAQCGE
VLKGVLKPPQCKLFGRECTPEHPIGALMVSNEGACAAYYHYVHRLSATRSA

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=371, Percent_Identity=53.3692722371968, Blast_Score=410, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41255; Mature: 41255

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVDELRDPKLIRAVAAEIWRAVDPERHYRIMEVCGGHTHAIYRHGLPELLPPMIELVH
CCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHC
GPGCPVCVLPMGRIDDGLALAEQPNVIFAAFGDMMRVPGRKGTPLEYQARGADVRMVYSP
CCCCCEEEEECCCCCCCCEECCCCCEEEEEHHHHHHCCCCCCCCCEEEECCCCEEEEECC
LDALKLAQANPQKHVVFFAIGFETTAPSTALTLMRAKQLGIRNFSVFCNHVLIVPAIRAI
HHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LDSPDMRLDGFIGPGHVSTVIGCRPYLFVARDYGKPLVVSGFEPLDLLQAILMILRQLRE
HCCCCCEECCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHH
GRAEVENQYRRVVPWNGNPAALKAMAEVFELRPYFEWRGLGFISQSAFKIAPAYADWDAE
HHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCHHCCCCCHHCCCCCEEECCCCCCCCE
VRFDIPGIRVTDPKAAQCGEVLKGVLKPPQCKLFGRECTPEHPIGALMVSNEGACAAYYH
EEEECCCEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHH
YVHRLSATRSA
HHHHHHHHCCC
>Mature Secondary Structure
MRYVDELRDPKLIRAVAAEIWRAVDPERHYRIMEVCGGHTHAIYRHGLPELLPPMIELVH
CCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHC
GPGCPVCVLPMGRIDDGLALAEQPNVIFAAFGDMMRVPGRKGTPLEYQARGADVRMVYSP
CCCCCEEEEECCCCCCCCEECCCCCEEEEEHHHHHHCCCCCCCCCEEEECCCCEEEEECC
LDALKLAQANPQKHVVFFAIGFETTAPSTALTLMRAKQLGIRNFSVFCNHVLIVPAIRAI
HHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LDSPDMRLDGFIGPGHVSTVIGCRPYLFVARDYGKPLVVSGFEPLDLLQAILMILRQLRE
HCCCCCEECCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHH
GRAEVENQYRRVVPWNGNPAALKAMAEVFELRPYFEWRGLGFISQSAFKIAPAYADWDAE
HHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCHHCCCCCHHCCCCCEEECCCCCCCCE
VRFDIPGIRVTDPKAAQCGEVLKGVLKPPQCKLFGRECTPEHPIGALMVSNEGACAAYYH
EEEECCCEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHH
YVHRLSATRSA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]