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The map label for this gene is appC [H]

Identifier: 221633813

GI number: 221633813

Start: 1849639

End: 1850544

Strand: Reverse

Name: appC [H]

Synonym: trd_1840

Alternate gene names: 221633813

Gene position: 1850544-1849639 (Counterclockwise)

Preceding gene: 221633814

Following gene: 221633812

Centisome position: 92.39

GC content: 63.36

Gene sequence:

>906_bases
ATGGTCGTTTCGACTCCTCTCCGACGGTCCGGTTCTCGAGCAGGACTTCCCGTCGTACCCCGCCGTACCCGTGCGCGGCC
CGACTGGCCGCTGACCTCGCTGCTGGCGGTCGTGTGGCTCGTCGGGATCAGCGTTGCCGCGTTGGCTGTCCCGCTCTTGC
CGCTTCCCGATCCCTCGACCCAGGACTTGCTGGCTCGTCTGCAGCCACCCGTCGGATTCGGTGGCACGTTGGCACATCCT
CTGGGAACTGACCAACTGGGCCGCGACCTGGCCAGCCGGATTCTCGCTGGAACGCGTGTCTCCTTGTCCTTGGCTTTGGT
GGGGGTCATCATCAGCGCCGTCGTGGGGACGAGCCTCGGGATCATCGCCGGGTATCGGCGTGGGTTACCCGACCACGTGA
TCAGCCTGTCGATCGACGTGCAGCTGGCTGTGCCGTTCATCGTCCTAGCGTTGATCGCTTTGACGCTCTTTGGCACCGGT
TTGACTGTCCTCATCATTTTGCTCGGACTGAGCGGGTGGGAGCAGTACGCGCGCATTGCACGCGCCAATACGCTCCGGCT
CAGGAACGAACTCTTCGTGGTCGCTGCGCAAGCTGCTGGAGCGAGCCCCGCCCGCATTCTCGCGCGCCACATTTTGCCGA
ACGAAGTCGCACCGCTCCTCGTCTTGATGACGCTGCACCTGACCAGTCTCGTCTTGTTGGAATCGTCCCTGAGTTTCCTC
GGGATCGGCGTGCAGCCACCGACACCCAGTCTCGGCAATATTCTGGGCGATGCCCGCAATTACCTGCAGATCGCGTGGTG
GCTCCCCGTCTTCCCCGGTGCTGTCCTTCTGGCGATCACCCTCTCGTTCAACGAACTCGGCGACTGGCTGCGCGACGTAA
CTGATCCTACGACGAGGGGACGTTGA

Upstream 100 bases:

>100_bases
CGGCGTTCTGCTTATCGTGGCCTCGGTGGTGTTGGTCAACCTCCTGACCGACATCCTGTACGGCTGGCTCGATCCTCGCG
TGCGGCTGGAGGCATGAGCG

Downstream 100 bases:

>100_bases
CCCCGGGTACGGCGAAAGGAGGCCAAGCAGCGAACAAAGAGCAGTTCTTCAACCAGTCGTCCTGAACCGGTCATGCGCTG
CCAGCAGAGAAGAGTCAGCG

Product: dipeptide transport system permease dppC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MVVSTPLRRSGSRAGLPVVPRRTRARPDWPLTSLLAVVWLVGISVAALAVPLLPLPDPSTQDLLARLQPPVGFGGTLAHP
LGTDQLGRDLASRILAGTRVSLSLALVGVIISAVVGTSLGIIAGYRRGLPDHVISLSIDVQLAVPFIVLALIALTLFGTG
LTVLIILLGLSGWEQYARIARANTLRLRNELFVVAAQAAGASPARILARHILPNEVAPLLVLMTLHLTSLVLLESSLSFL
GIGVQPPTPSLGNILGDARNYLQIAWWLPVFPGAVLLAITLSFNELGDWLRDVTDPTTRGR

Sequences:

>Translated_301_residues
MVVSTPLRRSGSRAGLPVVPRRTRARPDWPLTSLLAVVWLVGISVAALAVPLLPLPDPSTQDLLARLQPPVGFGGTLAHP
LGTDQLGRDLASRILAGTRVSLSLALVGVIISAVVGTSLGIIAGYRRGLPDHVISLSIDVQLAVPFIVLALIALTLFGTG
LTVLIILLGLSGWEQYARIARANTLRLRNELFVVAAQAAGASPARILARHILPNEVAPLLVLMTLHLTSLVLLESSLSFL
GIGVQPPTPSLGNILGDARNYLQIAWWLPVFPGAVLLAITLSFNELGDWLRDVTDPTTRGR
>Mature_301_residues
MVVSTPLRRSGSRAGLPVVPRRTRARPDWPLTSLLAVVWLVGISVAALAVPLLPLPDPSTQDLLARLQPPVGFGGTLAHP
LGTDQLGRDLASRILAGTRVSLSLALVGVIISAVVGTSLGIIAGYRRGLPDHVISLSIDVQLAVPFIVLALIALTLFGTG
LTVLIILLGLSGWEQYARIARANTLRLRNELFVVAAQAAGASPARILARHILPNEVAPLLVLMTLHLTSLVLLESSLSFL
GIGVQPPTPSLGNILGDARNYLQIAWWLPVFPGAVLLAITLSFNELGDWLRDVTDPTTRGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=280, Percent_Identity=37.1428571428571, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1787760, Length=251, Percent_Identity=36.2549800796813, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789964, Length=244, Percent_Identity=40.1639344262295, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787498, Length=222, Percent_Identity=37.3873873873874, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=37.1428571428571, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788505, Length=219, Percent_Identity=34.2465753424658, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787549, Length=220, Percent_Identity=34.0909090909091, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31938; Mature: 31938

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSTPLRRSGSRAGLPVVPRRTRARPDWPLTSLLAVVWLVGISVAALAVPLLPLPDPST
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
QDLLARLQPPVGFGGTLAHPLGTDQLGRDLASRILAGTRVSLSLALVGVIISAVVGTSLG
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IIAGYRRGLPDHVISLSIDVQLAVPFIVLALIALTLFGTGLTVLIILLGLSGWEQYARIA
HHHHHHCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RANTLRLRNELFVVAAQAAGASPARILARHILPNEVAPLLVLMTLHLTSLVLLESSLSFL
HHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
GIGVQPPTPSLGNILGDARNYLQIAWWLPVFPGAVLLAITLSFNELGDWLRDVTDPTTRG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
R
C
>Mature Secondary Structure
MVVSTPLRRSGSRAGLPVVPRRTRARPDWPLTSLLAVVWLVGISVAALAVPLLPLPDPST
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
QDLLARLQPPVGFGGTLAHPLGTDQLGRDLASRILAGTRVSLSLALVGVIISAVVGTSLG
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IIAGYRRGLPDHVISLSIDVQLAVPFIVLALIALTLFGTGLTVLIILLGLSGWEQYARIA
HHHHHHCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RANTLRLRNELFVVAAQAAGASPARILARHILPNEVAPLLVLMTLHLTSLVLLESSLSFL
HHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
GIGVQPPTPSLGNILGDARNYLQIAWWLPVFPGAVLLAITLSFNELGDWLRDVTDPTTRG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]