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The map label for this gene is dppA [H]

Identifier: 221633812

GI number: 221633812

Start: 1847821

End: 1849521

Strand: Reverse

Name: dppA [H]

Synonym: trd_1839

Alternate gene names: 221633812

Gene position: 1849521-1847821 (Counterclockwise)

Preceding gene: 221633813

Following gene: 221633811

Centisome position: 92.34

GC content: 61.9

Gene sequence:

>1701_bases
ATGGTCAACCGACCCACCCACAACGCCCGCTGCTGCTTCACGAGGCGACAGATCGTGGCAGGTTTGACCGTTTTACCGGG
TGCTTTGCTCCTCGCCTGCAACACGAGCGAGAGCACGCCGACCGCGACTCCTGCAACGACGCCTGCCAGCGCAGGCCAAG
CAGCGGCGCAGCCGACCAGCATGCCCTCTCCGACCGCAGCACCGGCTTCGGTCGCCACCGCGACAGCGGTGCCGCGCCGC
GAGTTGCGGATCGGCGTGCAAGGACTGCCACCGAACCTCGATCCACACCAACAGCTCTCGAACGTCGGCACGCGCGTGAC
GTATTCGATCTTCGACTACCTGATCCGGCGCGACTTCCTGAGCGGTCCGCAGCCAGGGGCTGGCTTCGCGCTCGTACCCT
GGGTCGCCAAGGAGTGGAAGCGGATCGATGATCTGACCGTCGAGTTCACCTTGCGCGACGACGTGACGTTCCACGACGGA
AGCATGCTGACTGCCGAGGATGTGGTCTTCACCTTCGAGCGGTTGTTGAAGAATACGCCGGATCAGTTGCGGGAGGCTGC
CAGCTACTTCAAAACAGTCGCAGAGATCAGTGCGCTGGACAGGAATCGAGTCCGCTTCGTGACCCAAAGCCCCGACCCTG
TTTTCGAAAAGCGGATCTCCTCGTGGGGCGGCTGGCTGATTCCCAAGGCGTACTATGAGCGAGTCGGCATGGATGGCTTC
GCTCGCGCGCCGATCGGCACCGGGCCATATCGTGTGGCGGAGTTCGTGACCGACGAGCGGCTCGTGCTCGAGCCCCACGA
GACGTACTTCGGTGGACGCCCGACGGCCTCCCGGATCGTCTTCCAAGTCATTCCCGAGATCCAGGCCCGAGTCGCCGCGC
TCTTGTCCGGGGAGGTCGACCTCATCACCAACGTGCCGCCGGACCAGGTACCGGTGCTCCAGCGGAGCCAAGGAATCGTC
ATCCGCAGCATTCCGCTCGCCAACTGTCATGTGCTGCGCTACAACTGCAATCACCCACTCTTGAAGGACAAGCGACTGCG
TCAGGCACTCAATCTCGGCATCGACCGCGAACTCTTGATCAAGACACTGTGGAATGACCAGGCAGTCCGCATGCGCAGCC
ATCAGTTCGAGGATTACGGACCACTTTACAACCCCCAACGCCCCTACACGCCCTATGATCCAGACCGCGCTCGCCAACTC
GTCCGTCAGTCCGGCTACGACGGCAGCACGATTCGCTACAACAACAAACCGGGCTACTATACGCTCGGCAATGAAGCAGC
CCAGGCAATCGTCGAGATGTGGCGCCAGATCGGCGTGAACGCTGAAGTCCAGCTGATCGACTGGGCCGATCTCCCCAAGG
AAGAGCGGATGGTTGGGTCTTGGTCGAACTCCAACTACTTGGCCGATCCGGAGGGAGCCTTCTGGTTGCGCTGGGGTCCG
GGGACGGCGACCCAGCGTGACTGGTGGAAGCCGGAGAATCCGCGCTTCAACGAGCTCGGCGAGCAACAACGGCAGACGCT
CGATCAGCAGTTCAGGGCACGGGCTTTTCAGGATGCGCTCGACATTTGGGAGGAGGAGGCACCCGGAACCGTCCTCTGGA
TCCCGATCGAGCACTATGCCATGCGCGATTTCGTCAAGTGGACCCCTTACAGCTTTTACTATATGGATCTGCGGCCCGAT
AACCTTTTGTTGGCCGGTTGA

Upstream 100 bases:

>100_bases
GGAGGCCAAGCAGCGAACAAAGAGCAGTTCTTCAACCAGTCGTCCTGAACCGGTCATGCGCTGCCAGCAGAGAAGAGTCA
GCGAAGGAAGGAGTAGTCCG

Downstream 100 bases:

>100_bases
GGGAGAGGACTACAGCAGTGGCGACTAGCCGTGTCCTGATCGTGGTACTCGACGGGCTCCGCCCTGACCTGGTTACCGAG
GAACGCATGCCCTTTGTCCA

Product: oligopeptide ABC transporter oligopeptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MVNRPTHNARCCFTRRQIVAGLTVLPGALLLACNTSESTPTATPATTPASAGQAAAQPTSMPSPTAAPASVATATAVPRR
ELRIGVQGLPPNLDPHQQLSNVGTRVTYSIFDYLIRRDFLSGPQPGAGFALVPWVAKEWKRIDDLTVEFTLRDDVTFHDG
SMLTAEDVVFTFERLLKNTPDQLREAASYFKTVAEISALDRNRVRFVTQSPDPVFEKRISSWGGWLIPKAYYERVGMDGF
ARAPIGTGPYRVAEFVTDERLVLEPHETYFGGRPTASRIVFQVIPEIQARVAALLSGEVDLITNVPPDQVPVLQRSQGIV
IRSIPLANCHVLRYNCNHPLLKDKRLRQALNLGIDRELLIKTLWNDQAVRMRSHQFEDYGPLYNPQRPYTPYDPDRARQL
VRQSGYDGSTIRYNNKPGYYTLGNEAAQAIVEMWRQIGVNAEVQLIDWADLPKEERMVGSWSNSNYLADPEGAFWLRWGP
GTATQRDWWKPENPRFNELGEQQRQTLDQQFRARAFQDALDIWEEEAPGTVLWIPIEHYAMRDFVKWTPYSFYYMDLRPD
NLLLAG

Sequences:

>Translated_566_residues
MVNRPTHNARCCFTRRQIVAGLTVLPGALLLACNTSESTPTATPATTPASAGQAAAQPTSMPSPTAAPASVATATAVPRR
ELRIGVQGLPPNLDPHQQLSNVGTRVTYSIFDYLIRRDFLSGPQPGAGFALVPWVAKEWKRIDDLTVEFTLRDDVTFHDG
SMLTAEDVVFTFERLLKNTPDQLREAASYFKTVAEISALDRNRVRFVTQSPDPVFEKRISSWGGWLIPKAYYERVGMDGF
ARAPIGTGPYRVAEFVTDERLVLEPHETYFGGRPTASRIVFQVIPEIQARVAALLSGEVDLITNVPPDQVPVLQRSQGIV
IRSIPLANCHVLRYNCNHPLLKDKRLRQALNLGIDRELLIKTLWNDQAVRMRSHQFEDYGPLYNPQRPYTPYDPDRARQL
VRQSGYDGSTIRYNNKPGYYTLGNEAAQAIVEMWRQIGVNAEVQLIDWADLPKEERMVGSWSNSNYLADPEGAFWLRWGP
GTATQRDWWKPENPRFNELGEQQRQTLDQQFRARAFQDALDIWEEEAPGTVLWIPIEHYAMRDFVKWTPYSFYYMDLRPD
NLLLAG
>Mature_566_residues
MVNRPTHNARCCFTRRQIVAGLTVLPGALLLACNTSESTPTATPATTPASAGQAAAQPTSMPSPTAAPASVATATAVPRR
ELRIGVQGLPPNLDPHQQLSNVGTRVTYSIFDYLIRRDFLSGPQPGAGFALVPWVAKEWKRIDDLTVEFTLRDDVTFHDG
SMLTAEDVVFTFERLLKNTPDQLREAASYFKTVAEISALDRNRVRFVTQSPDPVFEKRISSWGGWLIPKAYYERVGMDGF
ARAPIGTGPYRVAEFVTDERLVLEPHETYFGGRPTASRIVFQVIPEIQARVAALLSGEVDLITNVPPDQVPVLQRSQGIV
IRSIPLANCHVLRYNCNHPLLKDKRLRQALNLGIDRELLIKTLWNDQAVRMRSHQFEDYGPLYNPQRPYTPYDPDRARQL
VRQSGYDGSTIRYNNKPGYYTLGNEAAQAIVEMWRQIGVNAEVQLIDWADLPKEERMVGSWSNSNYLADPEGAFWLRWGP
GTATQRDWWKPENPRFNELGEQQRQTLDQQFRARAFQDALDIWEEEAPGTVLWIPIEHYAMRDFVKWTPYSFYYMDLRPD
NLLLAG

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=503, Percent_Identity=24.2544731610338, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787762, Length=529, Percent_Identity=26.0869565217391, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1787551, Length=304, Percent_Identity=25, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789887, Length=393, Percent_Identity=26.2086513994911, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787052, Length=492, Percent_Identity=21.9512195121951, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081878, Length=408, Percent_Identity=23.0392156862745, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787495, Length=400, Percent_Identity=24, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789397, Length=524, Percent_Identity=22.3282442748092, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64108; Mature: 64108

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00109 PROTEIN_KINASE_TYR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNRPTHNARCCFTRRQIVAGLTVLPGALLLACNTSESTPTATPATTPASAGQAAAQPTS
CCCCCCCCCEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
MPSPTAAPASVATATAVPRRELRIGVQGLPPNLDPHQQLSNVGTRVTYSIFDYLIRRDFL
CCCCCCCCCHHHHHHHCCHHHHEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
SGPQPGAGFALVPWVAKEWKRIDDLTVEFTLRDDVTFHDGSMLTAEDVVFTFERLLKNTP
CCCCCCCCEEEHHHHHHHHHHCCCEEEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCCC
DQLREAASYFKTVAEISALDRNRVRFVTQSPDPVFEKRISSWGGWLIPKAYYERVGMDGF
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCC
ARAPIGTGPYRVAEFVTDERLVLEPHETYFGGRPTASRIVFQVIPEIQARVAALLSGEVD
CCCCCCCCHHHHHHHHCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
LITNVPPDQVPVLQRSQGIVIRSIPLANCHVLRYNCNHPLLKDKRLRQALNLGIDRELLI
EEECCCCCCCCHHHCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHH
KTLWNDQAVRMRSHQFEDYGPLYNPQRPYTPYDPDRARQLVRQSGYDGSTIRYNNKPGYY
HHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCEE
TLGNEAAQAIVEMWRQIGVNAEVQLIDWADLPKEERMVGSWSNSNYLADPEGAFWLRWGP
ECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHEECCCCCCEEECCCCCEEEEECC
GTATQRDWWKPENPRFNELGEQQRQTLDQQFRARAFQDALDIWEEEAPGTVLWIPIEHYA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
MRDFVKWTPYSFYYMDLRPDNLLLAG
HHHHHHCCCCEEEEEEECCCCEEECC
>Mature Secondary Structure
MVNRPTHNARCCFTRRQIVAGLTVLPGALLLACNTSESTPTATPATTPASAGQAAAQPTS
CCCCCCCCCEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
MPSPTAAPASVATATAVPRRELRIGVQGLPPNLDPHQQLSNVGTRVTYSIFDYLIRRDFL
CCCCCCCCCHHHHHHHCCHHHHEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
SGPQPGAGFALVPWVAKEWKRIDDLTVEFTLRDDVTFHDGSMLTAEDVVFTFERLLKNTP
CCCCCCCCEEEHHHHHHHHHHCCCEEEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCCC
DQLREAASYFKTVAEISALDRNRVRFVTQSPDPVFEKRISSWGGWLIPKAYYERVGMDGF
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCC
ARAPIGTGPYRVAEFVTDERLVLEPHETYFGGRPTASRIVFQVIPEIQARVAALLSGEVD
CCCCCCCCHHHHHHHHCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
LITNVPPDQVPVLQRSQGIVIRSIPLANCHVLRYNCNHPLLKDKRLRQALNLGIDRELLI
EEECCCCCCCCHHHCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHH
KTLWNDQAVRMRSHQFEDYGPLYNPQRPYTPYDPDRARQLVRQSGYDGSTIRYNNKPGYY
HHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCEE
TLGNEAAQAIVEMWRQIGVNAEVQLIDWADLPKEERMVGSWSNSNYLADPEGAFWLRWGP
ECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHEECCCCCCEEECCCCCEEEEECC
GTATQRDWWKPENPRFNELGEQQRQTLDQQFRARAFQDALDIWEEEAPGTVLWIPIEHYA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
MRDFVKWTPYSFYYMDLRPDNLLLAG
HHHHHHCCCCEEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]