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The map label for this gene is argC

Identifier: 221633496

GI number: 221633496

Start: 1498350

End: 1499408

Strand: Reverse

Name: argC

Synonym: trd_1518

Alternate gene names: 221633496

Gene position: 1499408-1498350 (Counterclockwise)

Preceding gene: 221633497

Following gene: 221633495

Centisome position: 74.86

GC content: 63.93

Gene sequence:

>1059_bases
ATGGTCGTATCGGTCGCGATCTTGGGGGGCTCTGGGTATACGGGTGGTGAATTGCTTCGCTTGCTGTTGAGCCACCCCGA
AGTCGAGGTGAAGCAGGTCACGTCACGCTCGCGCGCGGGAAAGTTCGTACACACCGTACATCCGAACCTGCGGAAGCGGA
CAGCGCTCAAATTCGTCCCGCCCGAAGCGCTCGAGCCGGTCGATCTGCTCTTTGCCTGCTTGCCACACGGGGAAACGGCA
CCGATCGTCGACCGGCTTCTCGAGCTGGCGCCGATCGTGATCGACCTTTCCGCGGACTTCCGGTTGCGGGATCCCGCGGC
CTACGAGCAGTGGTACCACTGGACGCACCCGAGGCCCGATCTCCTGGCACAGGCCGTCTACGGCCTGCCAGAGTTGCATC
GGGAGGAGATCCGCAACGCGCGCTATATCGCCTGCCCGGGCTGCAATTCGACCACGGTCATCCTCGGTTTGGCCCCGCTG
TTCCGGGCTGGCTTGATCGACCTCGACCTCCCTGTCACCGTCGAGTGCAAGGTCGGCTCATCGGGCGCTGGTGGTGAGGC
TGGGCCGGCCAGTCATCATCCGGAGCGGAGCGGCGTGATCCGCCCCTTCAAGCCAGGTGGACACCGCCATACCGCCGAAG
TGCTGCAGGAACTCACTGTGTGCGGGCGAACCCCATCGCTCGGTCTGTCGGTAACGAGCGTGGAGGCAGTGCGCGGGATC
TTGGCGACCGCTCACCTCTTCCCTAAGCAGCCGCTGACGGACCGCGACCTTTGGCAGGTCTACCGGGCAGCGTATGGGCA
AGAGCCGTTCATTCGTCTGGTCAAAGAGGCCAGCGGTATTCACCGCTATCCGGAACCGAAGATCTTGGCCGGCTCGAATT
ATTGCGACATCGGCTGGGAGTTGGACGAGCTGCCAGGTGGACGCCAGCGTCTGGTAGTGATGTCGGCGATCGACAACCTG
ATGAAGGGGGCGGCCGGCCAGGCGGTGCAAGCGATGAATATCCGGCTCGGTTTCCCCGAGACGTTGGGTCTGGAGTTCCC
CGGTCTCCACCCGCTGTGA

Upstream 100 bases:

>100_bases
ATCGCCGATTACGTGCTCGCGCGGGCGACGCGAGGTGCGTCGCCCGCGATCGCATTGAGCCGGTGAAACGTTCGCCGACG
GGAGGGAGAGGCGGTCACGG

Downstream 100 bases:

>100_bases
GGACAGAAGCGTGCGACGTCGGTGGTTGGTCGTCGGCATCTTTGCGCTCGGGATCGGTCTCGGTTGGGTCCTCGCCCGGC
GGCGACCCTTCTCGGCGCGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MVVSVAILGGSGYTGGELLRLLLSHPEVEVKQVTSRSRAGKFVHTVHPNLRKRTALKFVPPEALEPVDLLFACLPHGETA
PIVDRLLELAPIVIDLSADFRLRDPAAYEQWYHWTHPRPDLLAQAVYGLPELHREEIRNARYIACPGCNSTTVILGLAPL
FRAGLIDLDLPVTVECKVGSSGAGGEAGPASHHPERSGVIRPFKPGGHRHTAEVLQELTVCGRTPSLGLSVTSVEAVRGI
LATAHLFPKQPLTDRDLWQVYRAAYGQEPFIRLVKEASGIHRYPEPKILAGSNYCDIGWELDELPGGRQRLVVMSAIDNL
MKGAAGQAVQAMNIRLGFPETLGLEFPGLHPL

Sequences:

>Translated_352_residues
MVVSVAILGGSGYTGGELLRLLLSHPEVEVKQVTSRSRAGKFVHTVHPNLRKRTALKFVPPEALEPVDLLFACLPHGETA
PIVDRLLELAPIVIDLSADFRLRDPAAYEQWYHWTHPRPDLLAQAVYGLPELHREEIRNARYIACPGCNSTTVILGLAPL
FRAGLIDLDLPVTVECKVGSSGAGGEAGPASHHPERSGVIRPFKPGGHRHTAEVLQELTVCGRTPSLGLSVTSVEAVRGI
LATAHLFPKQPLTDRDLWQVYRAAYGQEPFIRLVKEASGIHRYPEPKILAGSNYCDIGWELDELPGGRQRLVVMSAIDNL
MKGAAGQAVQAMNIRLGFPETLGLEFPGLHPL
>Mature_352_residues
MVVSVAILGGSGYTGGELLRLLLSHPEVEVKQVTSRSRAGKFVHTVHPNLRKRTALKFVPPEALEPVDLLFACLPHGETA
PIVDRLLELAPIVIDLSADFRLRDPAAYEQWYHWTHPRPDLLAQAVYGLPELHREEIRNARYIACPGCNSTTVILGLAPL
FRAGLIDLDLPVTVECKVGSSGAGGEAGPASHHPERSGVIRPFKPGGHRHTAEVLQELTVCGRTPSLGLSVTSVEAVRGI
LATAHLFPKQPLTDRDLWQVYRAAYGQEPFIRLVKEASGIHRYPEPKILAGSNYCDIGWELDELPGGRQRLVVMSAIDNL
MKGAAGQAVQAMNIRLGFPETLGLEFPGLHPL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=351, Percent_Identity=33.9031339031339, Blast_Score=171, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6320913, Length=349, Percent_Identity=29.2263610315186, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_THERP (B9KZP8)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002522721.1
- ProteinModelPortal:   B9KZP8
- GeneID:   7356076
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_1518
- OMA:   GCMATAS
- ProtClustDB:   CLSK2808046
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38378; Mature: 38378

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSVAILGGSGYTGGELLRLLLSHPEVEVKQVTSRSRAGKFVHTVHPNLRKRTALKFVP
CEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHHCEEEECC
PEALEPVDLLFACLPHGETAPIVDRLLELAPIVIDLSADFRLRDPAAYEQWYHWTHPRPD
CHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCEECCCHHHHHHHCCCCCCHH
LLAQAVYGLPELHREEIRNARYIACPGCNSTTVILGLAPLFRAGLIDLDLPVTVECKVGS
HHHHHHHCCHHHHHHHHCCCCEEECCCCCCCEEEEECHHHHHCCCEECCCCEEEEEEECC
SGAGGEAGPASHHPERSGVIRPFKPGGHRHTAEVLQELTVCGRTPSLGLSVTSVEAVRGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
LATAHLFPKQPLTDRDLWQVYRAAYGQEPFIRLVKEASGIHRYPEPKILAGSNYCDIGWE
HHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEECCCEEECCCC
LDELPGGRQRLVVMSAIDNLMKGAAGQAVQAMNIRLGFPETLGLEFPGLHPL
HHCCCCCHHEEHHHHHHHHHHHCCCCCEEEEEEEEECCCHHCCCCCCCCCCC
>Mature Secondary Structure
MVVSVAILGGSGYTGGELLRLLLSHPEVEVKQVTSRSRAGKFVHTVHPNLRKRTALKFVP
CEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHHCEEEECC
PEALEPVDLLFACLPHGETAPIVDRLLELAPIVIDLSADFRLRDPAAYEQWYHWTHPRPD
CHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCEECCCHHHHHHHCCCCCCHH
LLAQAVYGLPELHREEIRNARYIACPGCNSTTVILGLAPLFRAGLIDLDLPVTVECKVGS
HHHHHHHCCHHHHHHHHCCCCEEECCCCCCCEEEEECHHHHHCCCEECCCCEEEEEEECC
SGAGGEAGPASHHPERSGVIRPFKPGGHRHTAEVLQELTVCGRTPSLGLSVTSVEAVRGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
LATAHLFPKQPLTDRDLWQVYRAAYGQEPFIRLVKEASGIHRYPEPKILAGSNYCDIGWE
HHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEECCCEEECCCC
LDELPGGRQRLVVMSAIDNLMKGAAGQAVQAMNIRLGFPETLGLEFPGLHPL
HHCCCCCHHEEHHHHHHHHHHHCCCCCEEEEEEEEECCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA