Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 221633209

GI number: 221633209

Start: 1212182

End: 1213456

Strand: Reverse

Name: murA [H]

Synonym: trd_1226

Alternate gene names: 221633209

Gene position: 1213456-1212182 (Counterclockwise)

Preceding gene: 221633210

Following gene: 221633208

Centisome position: 60.58

GC content: 62.59

Gene sequence:

>1275_bases
GTGGCCATCACGACAGCCACCGAGCGAATCCGGACGATCGGCGGTCGCGTCCTGCGAGGACGTGTCGCGATCGGCGGCGC
AAAAAATGCGGCTCTGCCGGCGATGGCTGCGGCACTCCTCACCGAAGAAGAATGCGTCCTCGAGAACGTGCCGCTCCTCG
AAGATGTCGTCGTCATGACCGAGTTGCTACGGGCGCTCGGTGCCGAGGTCGATCTCGACACCGAGCGTCACCGCGTCCGC
ATTCGTGCTGCCGATATCGAGTCGTTCGAGCCGCCCCCTGAACTCGTCGCGCGCATGAGAGCGTCCTTTCTCGTGACCGG
TCCATTGCTGGCTCGATTCGGAAGGGCGCGCTCGATTCCTCCCGGTGGCTGCCAGCTCGGTAGTCGTCCAGTCGATGTCG
ATCTCCGCGGATTCCGCAAGTTCGGGGCACAGGTCGAAGTAACGGAAAGCGGCTTCGAGCTGCGGAGTGGACGGCTTCGC
GGCTGCGAGATCTACATGGATTATCCGAGCCATACCGGCACGGAAAATCTTTTGATGGCAGCCTGTTTGGCCCAGGGGAC
GACGACGATCCTCAATGCCGCGGCCGAGCCGGAAATCGTCAATCTCGGCCAAATCCTCCAGGATATGGGAGCCCGCATCA
ACGGACTGGGAACCTCGCGGATCGTCGTCCAGGGAGTCGATCGCTTGCGCGGATATCGTGCCTCTGTATTGCCTGATCGC
CTCGAGGCGGGGACGCTGGCGATCGCTGCCGCGATCACCCACGGCGAGGTGATCCTGGATCATGTACGGGAAGCTGACAT
GGCACCGCTGACGCACAAGTTGCGGGAAGCGGGAGCAGAAGTCTGGTGGAGCGAATCCTCGATGCTGGTGCGCGCTCCTG
GACCGCTCTACGCGACGGAAATTCAGGCGTTGCCCTTCCCAGGGTTCCCGACCGATCTCCAGGCGGCGTTTGCCGTCCTC
ATGACGCAAGCTCAGGGGCGGAGTCGTATTTTCGAGCGCGTGTTCAACGATCGTCTCCGCTACACGAGTGAGTTGCAGCG
GATGGGAGCACGGATCGAACTGATCGATCGCCAGCAGGCGATCATCGAAGGACCTGTCAAGCTGCAGGGTACAGCAGTGC
GTGCGCTCGATATTCGGAGCGGAGCCTGTCTGGTCTTGGCGGGTCTCGTCGCCGAAGGAGAAACGATCGTCCTCGAAGCC
CACCACTTGCGACGTGGCTACGAGGACTTGGTGGGCAAGCTGGCCGCGCTGGGCGCAGACATCCACTACGCGTGA

Upstream 100 bases:

>100_bases
GGCGCTCGACCATTCGATTGGCGGTCGGTCGCAAGCGACGAGCGCGAGCTGGAGTGGGTGGGCCACCGCTCCCCGAGGCG
CAACCCTGAAGGAGGTGGCC

Downstream 100 bases:

>100_bases
GTCTGTTCGCGCCGAGGGAGCTCGGTACCCCATGACGACGACACAGGGGCTGTGGCGTGCACGATTGCCGGTTCTCATTG
CGGGGGTGTTCGTGCTCGCC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAITTATERIRTIGGRVLRGRVAIGGAKNAALPAMAAALLTEEECVLENVPLLEDVVVMTELLRALGAEVDLDTERHRVR
IRAADIESFEPPPELVARMRASFLVTGPLLARFGRARSIPPGGCQLGSRPVDVDLRGFRKFGAQVEVTESGFELRSGRLR
GCEIYMDYPSHTGTENLLMAACLAQGTTTILNAAAEPEIVNLGQILQDMGARINGLGTSRIVVQGVDRLRGYRASVLPDR
LEAGTLAIAAAITHGEVILDHVREADMAPLTHKLREAGAEVWWSESSMLVRAPGPLYATEIQALPFPGFPTDLQAAFAVL
MTQAQGRSRIFERVFNDRLRYTSELQRMGARIELIDRQQAIIEGPVKLQGTAVRALDIRSGACLVLAGLVAEGETIVLEA
HHLRRGYEDLVGKLAALGADIHYA

Sequences:

>Translated_424_residues
MAITTATERIRTIGGRVLRGRVAIGGAKNAALPAMAAALLTEEECVLENVPLLEDVVVMTELLRALGAEVDLDTERHRVR
IRAADIESFEPPPELVARMRASFLVTGPLLARFGRARSIPPGGCQLGSRPVDVDLRGFRKFGAQVEVTESGFELRSGRLR
GCEIYMDYPSHTGTENLLMAACLAQGTTTILNAAAEPEIVNLGQILQDMGARINGLGTSRIVVQGVDRLRGYRASVLPDR
LEAGTLAIAAAITHGEVILDHVREADMAPLTHKLREAGAEVWWSESSMLVRAPGPLYATEIQALPFPGFPTDLQAAFAVL
MTQAQGRSRIFERVFNDRLRYTSELQRMGARIELIDRQQAIIEGPVKLQGTAVRALDIRSGACLVLAGLVAEGETIVLEA
HHLRRGYEDLVGKLAALGADIHYA
>Mature_423_residues
AITTATERIRTIGGRVLRGRVAIGGAKNAALPAMAAALLTEEECVLENVPLLEDVVVMTELLRALGAEVDLDTERHRVRI
RAADIESFEPPPELVARMRASFLVTGPLLARFGRARSIPPGGCQLGSRPVDVDLRGFRKFGAQVEVTESGFELRSGRLRG
CEIYMDYPSHTGTENLLMAACLAQGTTTILNAAAEPEIVNLGQILQDMGARINGLGTSRIVVQGVDRLRGYRASVLPDRL
EAGTLAIAAAITHGEVILDHVREADMAPLTHKLREAGAEVWWSESSMLVRAPGPLYATEIQALPFPGFPTDLQAAFAVLM
TQAQGRSRIFERVFNDRLRYTSELQRMGARIELIDRQQAIIEGPVKLQGTAVRALDIRSGACLVLAGLVAEGETIVLEAH
HLRRGYEDLVGKLAALGADIHYA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=44.5238095238095, Blast_Score=313, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45948; Mature: 45817

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITTATERIRTIGGRVLRGRVAIGGAKNAALPAMAAALLTEEECVLENVPLLEDVVVMT
CCCCHHHHHHHHHCCHHEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHH
ELLRALGAEVDLDTERHRVRIRAADIESFEPPPELVARMRASFLVTGPLLARFGRARSIP
HHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHEEECHHHHHHCCCCCCC
PGGCQLGSRPVDVDLRGFRKFGAQVEVTESGFELRSGRLRGCEIYMDYPSHTGTENLLMA
CCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCHHCCCCCCEEEEEEECCCCCCHHHHHHH
ACLAQGTTTILNAAAEPEIVNLGQILQDMGARINGLGTSRIVVQGVDRLRGYRASVLPDR
HHHHCCHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCH
LEAGTLAIAAAITHGEVILDHVREADMAPLTHKLREAGAEVWWSESSMLVRAPGPLYATE
HCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCCEEEECCCCEEEHE
IQALPFPGFPTDLQAAFAVLMTQAQGRSRIFERVFNDRLRYTSELQRMGARIELIDRQQA
EEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
IIEGPVKLQGTAVRALDIRSGACLVLAGLVAEGETIVLEAHHLRRGYEDLVGKLAALGAD
HHCCCCEECCEEEEEEECCCCCHHHHHHHHCCCCEEEEECHHHHCCHHHHHHHHHHHCCC
IHYA
CCCC
>Mature Secondary Structure 
AITTATERIRTIGGRVLRGRVAIGGAKNAALPAMAAALLTEEECVLENVPLLEDVVVMT
CCCHHHHHHHHHCCHHEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHH
ELLRALGAEVDLDTERHRVRIRAADIESFEPPPELVARMRASFLVTGPLLARFGRARSIP
HHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHEEECHHHHHHCCCCCCC
PGGCQLGSRPVDVDLRGFRKFGAQVEVTESGFELRSGRLRGCEIYMDYPSHTGTENLLMA
CCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCHHCCCCCCEEEEEEECCCCCCHHHHHHH
ACLAQGTTTILNAAAEPEIVNLGQILQDMGARINGLGTSRIVVQGVDRLRGYRASVLPDR
HHHHCCHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCH
LEAGTLAIAAAITHGEVILDHVREADMAPLTHKLREAGAEVWWSESSMLVRAPGPLYATE
HCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCCCEEEECCCCEEEHE
IQALPFPGFPTDLQAAFAVLMTQAQGRSRIFERVFNDRLRYTSELQRMGARIELIDRQQA
EEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
IIEGPVKLQGTAVRALDIRSGACLVLAGLVAEGETIVLEAHHLRRGYEDLVGKLAALGAD
HHCCCCEECCEEEEEEECCCCCHHHHHHHHCCCCEEEEECHHHHCCHHHHHHHHHHHCCC
IHYA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA