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The map label for this gene is resA [H]

Identifier: 221633208

GI number: 221633208

Start: 1211542

End: 1212150

Strand: Reverse

Name: resA [H]

Synonym: trd_1225

Alternate gene names: 221633208

Gene position: 1212150-1211542 (Counterclockwise)

Preceding gene: 221633209

Following gene: 221633207

Centisome position: 60.52

GC content: 63.71

Gene sequence:

>609_bases
ATGACGACGACACAGGGGCTGTGGCGTGCACGATTGCCGGTTCTCATTGCGGGGGTGTTCGTGCTCGCCTTCGTCGCGCT
GGTTGCCGTCGCATTCGAACGGCAACGTGGGACGAGCGAACTCGGAGCAGGTGGCCGCATCAACACGGTCGGGACCTTCA
TCCGCTTTGCGAATCGTGCAGCGCCCGACTTCACACTGCCCGATCTCCGGGGCGGGAAAGACATCGCGCTCGCTGACCTG
CGTGGTCAGGTGGTCATCGTCAATTTCTGGGGATCCTGGTGCCCGCCATGCCGCGAGGAGGCGCCGGTGCTGGCTGCCTT
CGCCCGCGAGTATGCGGACGACGGCGTCACCGTCGTCGGGATCGACGTCTGGGAAAAGGATTGGAACGACGGACGGGCCT
TTCTCGAGGAGTTCCGGGTCGACTATCCGAACGTGTACGATGCCCGCGGCCGTGTCACGATCGACTACGGGGTTTCCGGT
GTCCCGGAGACCTTCTTCATCGGCCCAGACGGGCAGTTGCTCGGGAAGTACACCGGCCCACTCAAGTCGGCCGATCAACT
TCTGAGCATCCTCGCGGAACTCGGTATTACCCTCAGCCCGATGCGCTGA

Upstream 100 bases:

>100_bases
TTGCGACGTGGCTACGAGGACTTGGTGGGCAAGCTGGCCGCGCTGGGCGCAGACATCCACTACGCGTGAGTCTGTTCGCG
CCGAGGGAGCTCGGTACCCC

Downstream 100 bases:

>100_bases
AGGATGCACCGAATGGAGCAGATCGATATCGCGGCGTTCGTGCGGATCGTGCTGCGGCTCGTCCATGCTCTCGCCGGCGC
CATCTGGCTCGGCAGCGGAG

Product: c-type cytochrome biogenesis protein/thioredoxin dsbE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTTTQGLWRARLPVLIAGVFVLAFVALVAVAFERQRGTSELGAGGRINTVGTFIRFANRAAPDFTLPDLRGGKDIALADL
RGQVVIVNFWGSWCPPCREEAPVLAAFAREYADDGVTVVGIDVWEKDWNDGRAFLEEFRVDYPNVYDARGRVTIDYGVSG
VPETFFIGPDGQLLGKYTGPLKSADQLLSILAELGITLSPMR

Sequences:

>Translated_202_residues
MTTTQGLWRARLPVLIAGVFVLAFVALVAVAFERQRGTSELGAGGRINTVGTFIRFANRAAPDFTLPDLRGGKDIALADL
RGQVVIVNFWGSWCPPCREEAPVLAAFAREYADDGVTVVGIDVWEKDWNDGRAFLEEFRVDYPNVYDARGRVTIDYGVSG
VPETFFIGPDGQLLGKYTGPLKSADQLLSILAELGITLSPMR
>Mature_201_residues
TTTQGLWRARLPVLIAGVFVLAFVALVAVAFERQRGTSELGAGGRINTVGTFIRFANRAAPDFTLPDLRGGKDIALADLR
GQVVIVNFWGSWCPPCREEAPVLAAFAREYADDGVTVVGIDVWEKDWNDGRAFLEEFRVDYPNVYDARGRVTIDYGVSGV
PETFFIGPDGQLLGKYTGPLKSADQLLSILAELGITLSPMR

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=127, Percent_Identity=30.7086614173228, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 22054; Mature: 21923

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTQGLWRARLPVLIAGVFVLAFVALVAVAFERQRGTSELGAGGRINTVGTFIRFANRA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCC
APDFTLPDLRGGKDIALADLRGQVVIVNFWGSWCPPCREEAPVLAAFAREYADDGVTVVG
CCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
IDVWEKDWNDGRAFLEEFRVDYPNVYDARGRVTIDYGVSGVPETFFIGPDGQLLGKYTGP
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCEECCCCCC
LKSADQLLSILAELGITLSPMR
CCCHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure 
TTTQGLWRARLPVLIAGVFVLAFVALVAVAFERQRGTSELGAGGRINTVGTFIRFANRA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCC
APDFTLPDLRGGKDIALADLRGQVVIVNFWGSWCPPCREEAPVLAAFAREYADDGVTVVG
CCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
IDVWEKDWNDGRAFLEEFRVDYPNVYDARGRVTIDYGVSGVPETFFIGPDGQLLGKYTGP
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCEECCCCCC
LKSADQLLSILAELGITLSPMR
CCCHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 12637552 [H]