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The map label for this gene is argK [C]

Identifier: 221632809

GI number: 221632809

Start: 785244

End: 786200

Strand: Reverse

Name: argK [C]

Synonym: trd_0803

Alternate gene names: 221632809

Gene position: 786200-785244 (Counterclockwise)

Preceding gene: 221632810

Following gene: 221632805

Centisome position: 39.25

GC content: 62.07

Gene sequence:

>957_bases
ATGTCGCAGGACTTGGGAAACTTGCTCGAAGGTGTTCGGAATCGGGATCGTTCCTCCCTTGCGCGCGCACTCTCCCTCTT
GGAGCGTTATCCTGACGTGGCTCATCTGCTTCCGCGCGAGCGCGGAGGACACGCAACGGTCGTCGCGGTGGCTGGGCCGC
CGGGAGCTGGCAAGAGTACTTTGCTGGGTCGGGTAGCTGCTGAAATCACAATGAGGGATATGTCGGTTGCTGTCCTCGCC
TTCGATCCGGTCAGCCCGCGTTCCGGAGGCGCCCTCCTCGGTGATCGGATCCGCATGCTCGACGCCGCGGAGCACCCCAA
CGTCTATGTGCGTTCCATCGCTGCGCGCGACCCGGCCGGTTCTCCCGTTCTCCCTGCGCTCCTCGCTGTCCTCGATCTTT
ATGGATTCGACTTCGTCTTTCTCGAAGCGGTCGGTGCCGGGCAGGAGGCTTCGCCGCTCCTCCTCGCCGCAGATCTCGCT
CTCCTCGTACTCGTCCCCGGGCTCGGCGATAGTGTGCAAACGTTGAAGGCGGGCGTTCTCGAGATTGCAGATCTTATCGT
GATCAACAAATCGGATCGTCCTGGTGCAGCTGAACTCGTTCGCGACCTTTCAGCTTACTACCGGCTCCTCGCCGATACGA
GTCACCCTGTTCCACCCATCCTGCAGACGGTCGGGAGCGAAGGACAGGGAATCACAGCGGTGCTCGAGGCGATCACTGAA
CTCCGAGATCGCTATGCCGCGAGTGGCATCCTCGAAGAACGGCGGCGCCGTGCTGCCACTCGTCTGTGGCAGCACACTCT
CCGCACGCGCTGTCTTCGCATCATCGACGAATTGCTGAACGACGGACCCGCGCCGGACGACGGCGATCATGAAATGGGCA
CTCGTGAGCGACAGCTTTACCGGAAACTTGCCGAGCGGTTCGCCCTACTTGCCGCCTCGTCGGACGATTCTCGCTGA

Upstream 100 bases:

>100_bases
GGGAGTTGCCGAAGTTTTCGGCCCCGGTACGCCGCTATCAGAAATCATTCGCTTCATCGAAACGCATGTTGGTGAGCCAG
TGAGGGGCGCGTGAGTCGAG

Downstream 100 bases:

>100_bases
CGGCGTTGACCAGCACAGCGATTCGCGATCTTAGCAGCAGCTGCTCCGGCCCCAACACCATTGTCGATATTGACGACGAC
CAGGCCGGGAGCGCAGGACT

Product: ArgK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSQDLGNLLEGVRNRDRSSLARALSLLERYPDVAHLLPRERGGHATVVAVAGPPGAGKSTLLGRVAAEITMRDMSVAVLA
FDPVSPRSGGALLGDRIRMLDAAEHPNVYVRSIAARDPAGSPVLPALLAVLDLYGFDFVFLEAVGAGQEASPLLLAADLA
LLVLVPGLGDSVQTLKAGVLEIADLIVINKSDRPGAAELVRDLSAYYRLLADTSHPVPPILQTVGSEGQGITAVLEAITE
LRDRYAASGILEERRRRAATRLWQHTLRTRCLRIIDELLNDGPAPDDGDHEMGTRERQLYRKLAERFALLAASSDDSR

Sequences:

>Translated_318_residues
MSQDLGNLLEGVRNRDRSSLARALSLLERYPDVAHLLPRERGGHATVVAVAGPPGAGKSTLLGRVAAEITMRDMSVAVLA
FDPVSPRSGGALLGDRIRMLDAAEHPNVYVRSIAARDPAGSPVLPALLAVLDLYGFDFVFLEAVGAGQEASPLLLAADLA
LLVLVPGLGDSVQTLKAGVLEIADLIVINKSDRPGAAELVRDLSAYYRLLADTSHPVPPILQTVGSEGQGITAVLEAITE
LRDRYAASGILEERRRRAATRLWQHTLRTRCLRIIDELLNDGPAPDDGDHEMGTRERQLYRKLAERFALLAASSDDSR
>Mature_317_residues
SQDLGNLLEGVRNRDRSSLARALSLLERYPDVAHLLPRERGGHATVVAVAGPPGAGKSTLLGRVAAEITMRDMSVAVLAF
DPVSPRSGGALLGDRIRMLDAAEHPNVYVRSIAARDPAGSPVLPALLAVLDLYGFDFVFLEAVGAGQEASPLLLAADLAL
LVLVPGLGDSVQTLKAGVLEIADLIVINKSDRPGAAELVRDLSAYYRLLADTSHPVPPILQTVGSEGQGITAVLEAITEL
RDRYAASGILEERRRRAATRLWQHTLRTRCLRIIDELLNDGPAPDDGDHEMGTRERQLYRKLAERFALLAASSDDSR

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=288, Percent_Identity=31.25, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1789285, Length=291, Percent_Identity=31.6151202749141, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994271, Length=290, Percent_Identity=28.6206896551724, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994275, Length=229, Percent_Identity=31.0043668122271, Blast_Score=110, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34183; Mature: 34051

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDLGNLLEGVRNRDRSSLARALSLLERYPDVAHLLPRERGGHATVVAVAGPPGAGKST
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEEECCCCCCHHH
LLGRVAAEITMRDMSVAVLAFDPVSPRSGGALLGDRIRMLDAAEHPNVYVRSIAARDPAG
HHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
SPVLPALLAVLDLYGFDFVFLEAVGAGQEASPLLLAADLALLVLVPGLGDSVQTLKAGVL
CCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EIADLIVINKSDRPGAAELVRDLSAYYRLLADTSHPVPPILQTVGSEGQGITAVLEAITE
HHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHH
LRDRYAASGILEERRRRAATRLWQHTLRTRCLRIIDELLNDGPAPDDGDHEMGTRERQLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RKLAERFALLAASSDDSR
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQDLGNLLEGVRNRDRSSLARALSLLERYPDVAHLLPRERGGHATVVAVAGPPGAGKST
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEEECCCCCCHHH
LLGRVAAEITMRDMSVAVLAFDPVSPRSGGALLGDRIRMLDAAEHPNVYVRSIAARDPAG
HHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
SPVLPALLAVLDLYGFDFVFLEAVGAGQEASPLLLAADLALLVLVPGLGDSVQTLKAGVL
CCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EIADLIVINKSDRPGAAELVRDLSAYYRLLADTSHPVPPILQTVGSEGQGITAVLEAITE
HHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHH
LRDRYAASGILEERRRRAATRLWQHTLRTRCLRIIDELLNDGPAPDDGDHEMGTRERQLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RKLAERFALLAASSDDSR
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]