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The map label for this gene is tenA [H]

Identifier: 221632565

GI number: 221632565

Start: 534138

End: 534782

Strand: Reverse

Name: tenA [H]

Synonym: trd_0540

Alternate gene names: 221632565

Gene position: 534782-534138 (Counterclockwise)

Preceding gene: 221632569

Following gene: 221632564

Centisome position: 26.7

GC content: 62.33

Gene sequence:

>645_bases
ATGCCCAGCACCTTGCTCGACGAGCTGCTCGCCGAAGCACGACCGATTTGGCAAGCGATGATCGCGCATCCCTTCCTGCA
CGAACTCGCGACCGGAACGCTCTCGCGCGAGCGCTTCCACTTTTGGGTTCAGCAGGATTACCGATTCGTCCAGGACGGCA
TCCGCTTCCTGGGCCTCCTGATCGCTCGCGCACCGGATGAGGAGCTCCGACGCGGACTGCTCGACGCAGCTGTCGCCTTC
CGCAACGAACTCACCATATTCGAGGAGTACGCCCGCCAGCACGCTCTCTCGCTCGCCGTCGAGCCGACGCCGATCTGTCT
CGGCTATACCTCTTTCCTCCTCGCGACCGCAGCCACCGGGTCCTTGGTCGAAGCCCTCACCGTTCTCTGGTGTGCGGAAA
AGGCATACTACGACGCGTGGTCAGCTGTTCGAGCACAACTCGGTCTCGCGCCAGCCTATGCGCGCTGGATCGAAAACTGG
ACGAGTCCGCAATTCGCGAGCTGGGTCGATTGGCTCGGCGAACAACTGGCCAAGCGAGCCACCACGCCAGACCGACCGCC
TATTCGGGCTGCCTTTCTGGCCACTGCTCGCTACGAGTACCTCTTCTGGGACATGGTCTATACCGGCTCCAACTGGCCCA
TATAG

Upstream 100 bases:

>100_bases
GACCTGATCTGGGTAATGCCAGCGAAGGGAGGCCATCCACTGATCCGTTCCCCTTGCACCATGTTCAGGAGGCACGTCGC
CGATCTTCGGGAGGTGCTCC

Downstream 100 bases:

>100_bases
CGAGAGGAGTGGATGATGACCAGCTTCACCCAAGAGCTCTGGCGCTCGATCGATCCGATCTACCAGGCGATCGTCGTTCA
CCCCTTCCTCGTCGGCCTGA

Product: TENA/THI-4 family

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MPSTLLDELLAEARPIWQAMIAHPFLHELATGTLSRERFHFWVQQDYRFVQDGIRFLGLLIARAPDEELRRGLLDAAVAF
RNELTIFEEYARQHALSLAVEPTPICLGYTSFLLATAATGSLVEALTVLWCAEKAYYDAWSAVRAQLGLAPAYARWIENW
TSPQFASWVDWLGEQLAKRATTPDRPPIRAAFLATARYEYLFWDMVYTGSNWPI

Sequences:

>Translated_214_residues
MPSTLLDELLAEARPIWQAMIAHPFLHELATGTLSRERFHFWVQQDYRFVQDGIRFLGLLIARAPDEELRRGLLDAAVAF
RNELTIFEEYARQHALSLAVEPTPICLGYTSFLLATAATGSLVEALTVLWCAEKAYYDAWSAVRAQLGLAPAYARWIENW
TSPQFASWVDWLGEQLAKRATTPDRPPIRAAFLATARYEYLFWDMVYTGSNWPI
>Mature_213_residues
PSTLLDELLAEARPIWQAMIAHPFLHELATGTLSRERFHFWVQQDYRFVQDGIRFLGLLIARAPDEELRRGLLDAAVAFR
NELTIFEEYARQHALSLAVEPTPICLGYTSFLLATAATGSLVEALTVLWCAEKAYYDAWSAVRAQLGLAPAYARWIENWT
SPQFASWVDWLGEQLAKRATTPDRPPIRAAFLATARYEYLFWDMVYTGSNWPI

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 24443; Mature: 24312

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTLLDELLAEARPIWQAMIAHPFLHELATGTLSRERFHFWVQQDYRFVQDGIRFLGLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARAPDEELRRGLLDAAVAFRNELTIFEEYARQHALSLAVEPTPICLGYTSFLLATAATG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCH
SLVEALTVLWCAEKAYYDAWSAVRAQLGLAPAYARWIENWTSPQFASWVDWLGEQLAKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
TTPDRPPIRAAFLATARYEYLFWDMVYTGSNWPI
CCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
PSTLLDELLAEARPIWQAMIAHPFLHELATGTLSRERFHFWVQQDYRFVQDGIRFLGLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARAPDEELRRGLLDAAVAFRNELTIFEEYARQHALSLAVEPTPICLGYTSFLLATAATG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCH
SLVEALTVLWCAEKAYYDAWSAVRAQLGLAPAYARWIENWTSPQFASWVDWLGEQLAKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
TTPDRPPIRAAFLATARYEYLFWDMVYTGSNWPI
CCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]