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The map label for this gene is serB [H]

Identifier: 221230403

GI number: 221230403

Start: 2083275

End: 2084510

Strand: Reverse

Name: serB [H]

Synonym: MLBr_01727

Alternate gene names: 221230403

Gene position: 2084510-2083275 (Counterclockwise)

Preceding gene: 221230404

Following gene: 221230402

Centisome position: 63.78

GC content: 63.19

Gene sequence:

>1236_bases
GTGAATACGCCACCCAAGGTGTCGGTGCTGATCACTGTCACCGGCGTGGATCAGCCAGGTGTGACGTCAGCGCTCTTCGC
GGTGCTTTCGCGGCACGGGGGCGAACTGCTCAACGTCGAGCAGGTGGTAATTCGGGGTCGGCTCACACTGGGTGTGCTGG
TGTTGTGCCCGCCGGAAGTTGCCGCTTATACCGCGTTGCGAGATGACGTGCAAGCCGCGATTCGCCGGGTCGGCCTTGAT
GTCACGATCGAGCGCAGTGACGACTTGCCGATCATCCGGGAACCGTCGACCCACACGATTTTTGTGCTGGGCCGTCCGAT
TACCGCTCGGGCGTTCGGCGCTGTAGCACGTGAGGTTGCGGCACTGGATGTCAATATCGACGTCATTCGAGGCATCTCCG
ACTACCCGGTTACCGGGCTGGAGTTGCGAGTCTCGGCGCCGTTGGAAGCCGCGGGATCGCTGCGGACAGCTCTCAACCGG
GTGGCTACCGAGGAACATGTCGACGTGGCAGTGGAGGGTTACGGTCTGGCCCGGCGCATCAAACGCCTCATTGTGTTTGA
CGTCGATTCCACTTTGGTCCAGGGTGAGGTGATTGAAATGCTGGCCGCCCGAGCTGGCGCCCAGGGAACGGTCGCCGCGA
TCACCGAGGCCGCGATGCGCGGTGAACTGGATTTCGCGGAATCGTTGCAGCAGCGGGTGGCCACCTTGGCGGGACTGCCT
GTCACGGTGGTCGATGAGGTGGCCAATCAGTTGCAGCTGATGCCAGGTGCTCGGACCACTCTGCGTACGCTGCGACGGCT
GGGGTTTCGTTGCGGGGTGGTGTCCGGAGGCTTTCGGCGGATCATCGAGCCGCTTGCGCACGAGCTGATGCTGGACTTCG
TCGCGGCCAATGAGTTAGAGATCGTCGACGGCATACTTACTGGCCGGGTGGTCGGCACAATCGTCGATCGGCCCGGTAAG
GCCAAGGCGTTACGCTACTTCTCAGAGCAGGCTGGTGTGCCGATGGAGCAGACCGTTGCCGTCGGTGACGGCGCCAATGA
CATCGACATGCTGACAGCGGCTGGGCTGGGAATTGCGTTTAACGCTAAGCCGGCGTTGCGTGCCGTCGCCGATGCGTCGT
TGAGCCATCCCTACCTGGACACGGTGCTTTTTGTGTTGGGTGTGACACGCGGAGAGATCGAGGCCGCGGACGCGGCCGAC
GGCGGGGTGCGCCGCGTCGAGATCCCTCCCGACTAG

Upstream 100 bases:

>100_bases
CGACGAGGCATACGTTGGGCGCCGTCACGCCGAGGAGCTCGTTGAGGTGAGTTTACACTGATACGGCTCGGCTTGGCCGG
CGCTGTCAGATGAGTCGCGA

Downstream 100 bases:

>100_bases
CCGCTTCCCGTGGCGACTTGGTCGAGGCTACCCGGCAACCGTCGCAGCATCGCGGTACGGCACGATGTCCGAGTGTCCCA
ACTTGGCCCTGAAACTGGCA

Product: putative phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNTPPKVSVLITVTGVDQPGVTSALFAVLSRHGGELLNVEQVVIRGRLTLGVLVLCPPEVAAYTALRDDVQAAIRRVGLD
VTIERSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVAALDVNIDVIRGISDYPVTGLELRVSAPLEAAGSLRTALNR
VATEEHVDVAVEGYGLARRIKRLIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQRVATLAGLP
VTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRIIEPLAHELMLDFVAANELEIVDGILTGRVVGTIVDRPGK
AKALRYFSEQAGVPMEQTVAVGDGANDIDMLTAAGLGIAFNAKPALRAVADASLSHPYLDTVLFVLGVTRGEIEAADAAD
GGVRRVEIPPD

Sequences:

>Translated_411_residues
MNTPPKVSVLITVTGVDQPGVTSALFAVLSRHGGELLNVEQVVIRGRLTLGVLVLCPPEVAAYTALRDDVQAAIRRVGLD
VTIERSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVAALDVNIDVIRGISDYPVTGLELRVSAPLEAAGSLRTALNR
VATEEHVDVAVEGYGLARRIKRLIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQRVATLAGLP
VTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRIIEPLAHELMLDFVAANELEIVDGILTGRVVGTIVDRPGK
AKALRYFSEQAGVPMEQTVAVGDGANDIDMLTAAGLGIAFNAKPALRAVADASLSHPYLDTVLFVLGVTRGEIEAADAAD
GGVRRVEIPPD
>Mature_411_residues
MNTPPKVSVLITVTGVDQPGVTSALFAVLSRHGGELLNVEQVVIRGRLTLGVLVLCPPEVAAYTALRDDVQAAIRRVGLD
VTIERSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVAALDVNIDVIRGISDYPVTGLELRVSAPLEAAGSLRTALNR
VATEEHVDVAVEGYGLARRIKRLIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQRVATLAGLP
VTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRIIEPLAHELMLDFVAANELEIVDGILTGRVVGTIVDRPGK
AKALRYFSEQAGVPMEQTVAVGDGANDIDMLTAAGLGIAFNAKPALRAVADASLSHPYLDTVLFVLGVTRGEIEAADAAD
GGVRRVEIPPD

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790849, Length=236, Percent_Identity=45.7627118644068, Blast_Score=185, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6321647, Length=300, Percent_Identity=36.3333333333333, Blast_Score=178, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43563; Mature: 43563

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPPKVSVLITVTGVDQPGVTSALFAVLSRHGGELLNVEQVVIRGRLTLGVLVLCPPEV
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCEECHHHHHHHCCCEEEEEEECCCHH
AAYTALRDDVQAAIRRVGLDVTIERSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVA
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHH
ALDVNIDVIRGISDYPVTGLELRVSAPLEAAGSLRTALNRVATEEHVDVAVEGYGLARRI
HEECCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCHHHCEEEEECCHHHHHH
KRLIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQRVATLAGLP
HHHEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
VTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRIIEPLAHELMLDFVAANELE
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCHH
IVDGILTGRVVGTIVDRPGKAKALRYFSEQAGVPMEQTVAVGDGANDIDMLTAAGLGIAF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHCCCCEEE
NAKPALRAVADASLSHPYLDTVLFVLGVTRGEIEAADAADGGVRRVEIPPD
CCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MNTPPKVSVLITVTGVDQPGVTSALFAVLSRHGGELLNVEQVVIRGRLTLGVLVLCPPEV
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCEECHHHHHHHCCCEEEEEEECCCHH
AAYTALRDDVQAAIRRVGLDVTIERSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVA
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHH
ALDVNIDVIRGISDYPVTGLELRVSAPLEAAGSLRTALNRVATEEHVDVAVEGYGLARRI
HEECCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCHHHCEEEEECCHHHHHH
KRLIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQRVATLAGLP
HHHEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
VTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRIIEPLAHELMLDFVAANELE
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCHH
IVDGILTGRVVGTIVDRPGKAKALRYFSEQAGVPMEQTVAVGDGANDIDMLTAAGLGIAF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHCCCCEEE
NAKPALRAVADASLSHPYLDTVLFVLGVTRGEIEAADAADGGVRRVEIPPD
CCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA