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The map label for this gene is abcX [H]

Identifier: 221230402

GI number: 221230402

Start: 2082348

End: 2083265

Strand: Reverse

Name: abcX [H]

Synonym: MLBr_01726

Alternate gene names: 221230402

Gene position: 2083265-2082348 (Counterclockwise)

Preceding gene: 221230403

Following gene: 221230401

Centisome position: 63.75

GC content: 63.4

Gene sequence:

>918_bases
GTGGCGACTTGGTCGAGGCTACCCGGCAACCGTCGCAGCATCGCGGTACGGCACGATGTCCGAGTGTCCCAACTTGGCCC
TGAAACTGGCAGCGACGCAGCCGATCCCGATCTGCTGATCGACTTTAAGGACGTATCCCTGCGCTGCGAAGGGCGTGTCC
TGGTTGGGCCGCTGGATTGGGCAGTGGAACTCGACGAACGCTGGGTGATTATCGGCCCCAATGGGGCCGGCAAGACGTCG
CTGTTGCGCATTGCTGCAGCGGCCGACCACCCGTCGACGGGCGTTGCCTATGTGCTCGGTGAGCGGTTGGGGCGCATAGA
CATCTCCGAGTTGCGTGCGCGCATTGGCCTGAGTTCGTCGGTTCTGACGCAGCGGGTGCCTAGCAATGAAGTGGTGCGCG
ATCTCGTGGTGTCGGCGGGCTATGCGGTGCTGGGACGCTGGCGCGAACGGTACGAAGGTGTCGACTACCAGCGAGCGGTC
GACATGCTGGAGAGTATGGGTGCCGAACACCTCGCCGACCGCACCTTCGGTACGCTGTCTGAAGGTGAGCGCAAGCGGGT
GCTGATCGCCCGGGCATTGATGACTGATCCGGAGCTACTGCTGCTCGATGAACCTGCCGCCAGTCTCGACTTGGGTGCTC
GCGAGGAGTTGGTCTCCCGGCTGGCTGATCTGGCCGCCGACGCGTATGCTCCGGCGCTAGTGCTCGTTACCCACCACGTG
GAGGAGGTTCCACCTGGCTTTAGCCACTGTCTGCTGCTGTCGGAGGCCAAGGTCGTCGCCGCGGGTTTGCTGTCCGACGT
GCTGACAGCAGAAAATCTGTCCACCGCGTTCGGTCAGTCGATCGCTCTGGATGTTATCGACGGGCGCTATTTCGCTCGCA
GAGTCCGCGCCCGAGCAGCTCACCGGAGGCAGTTATGA

Upstream 100 bases:

>100_bases
GCTTTTTGTGTTGGGTGTGACACGCGGAGAGATCGAGGCCGCGGACGCGGCCGACGGCGGGGTGCGCCGCGTCGAGATCC
CTCCCGACTAGCCGCTTCCC

Downstream 100 bases:

>100_bases
CGTCACCGCGACCGGCGGAGACCGTGATGCTGATTCGGGAGATTCCAGATAGTCCAGAGGGCTTGATCGTCTTTTTGATG
CGCCGGCACGCAGCGATGGA

Product: putative ABC transporter protein, ATP-binding component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MATWSRLPGNRRSIAVRHDVRVSQLGPETGSDAADPDLLIDFKDVSLRCEGRVLVGPLDWAVELDERWVIIGPNGAGKTS
LLRIAAAADHPSTGVAYVLGERLGRIDISELRARIGLSSSVLTQRVPSNEVVRDLVVSAGYAVLGRWRERYEGVDYQRAV
DMLESMGAEHLADRTFGTLSEGERKRVLIARALMTDPELLLLDEPAASLDLGAREELVSRLADLAADAYAPALVLVTHHV
EEVPPGFSHCLLLSEAKVVAAGLLSDVLTAENLSTAFGQSIALDVIDGRYFARRVRARAAHRRQL

Sequences:

>Translated_305_residues
MATWSRLPGNRRSIAVRHDVRVSQLGPETGSDAADPDLLIDFKDVSLRCEGRVLVGPLDWAVELDERWVIIGPNGAGKTS
LLRIAAAADHPSTGVAYVLGERLGRIDISELRARIGLSSSVLTQRVPSNEVVRDLVVSAGYAVLGRWRERYEGVDYQRAV
DMLESMGAEHLADRTFGTLSEGERKRVLIARALMTDPELLLLDEPAASLDLGAREELVSRLADLAADAYAPALVLVTHHV
EEVPPGFSHCLLLSEAKVVAAGLLSDVLTAENLSTAFGQSIALDVIDGRYFARRVRARAAHRRQL
>Mature_304_residues
ATWSRLPGNRRSIAVRHDVRVSQLGPETGSDAADPDLLIDFKDVSLRCEGRVLVGPLDWAVELDERWVIIGPNGAGKTSL
LRIAAAADHPSTGVAYVLGERLGRIDISELRARIGLSSSVLTQRVPSNEVVRDLVVSAGYAVLGRWRERYEGVDYQRAVD
MLESMGAEHLADRTFGTLSEGERKRVLIARALMTDPELLLLDEPAASLDLGAREELVSRLADLAADAYAPALVLVTHHVE
EVPPGFSHCLLLSEAKVVAAGLLSDVLTAENLSTAFGQSIALDVIDGRYFARRVRARAAHRRQL

Specific function: Part Of The Binding-Protein-Dependent Transport System For Ferric Enterobactin. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=268, Percent_Identity=26.1194029850746, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786803, Length=213, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786975, Length=244, Percent_Identity=32.7868852459016, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788761, Length=193, Percent_Identity=33.6787564766839, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787089, Length=204, Percent_Identity=31.8627450980392, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786319, Length=188, Percent_Identity=32.4468085106383, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786345, Length=244, Percent_Identity=25.8196721311475, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081709, Length=229, Percent_Identity=24.4541484716157, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.0970873786408, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786253, Length=216, Percent_Identity=25.462962962963, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788897, Length=236, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788450, Length=229, Percent_Identity=28.82096069869, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=30, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87081834, Length=182, Percent_Identity=28.021978021978, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786563, Length=197, Percent_Identity=30.9644670050761, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789032, Length=213, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790739, Length=210, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786872, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789864, Length=217, Percent_Identity=26.7281105990783, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788225, Length=233, Percent_Identity=26.1802575107296, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790467, Length=159, Percent_Identity=32.0754716981132, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787370, Length=196, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081791, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790544, Length=165, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788053, Length=205, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789963, Length=215, Percent_Identity=28.3720930232558, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788165, Length=176, Percent_Identity=26.7045454545455, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789593, Length=236, Percent_Identity=26.271186440678, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081782, Length=214, Percent_Identity=24.7663551401869, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=27.7777777777778, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1787792, Length=189, Percent_Identity=26.4550264550265, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17565586, Length=177, Percent_Identity=28.2485875706215, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320266, Length=228, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 33198; Mature: 33067

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATWSRLPGNRRSIAVRHDVRVSQLGPETGSDAADPDLLIDFKDVSLRCEGRVLVGPLDW
CCCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCEEEEEECCEEEECCEEEEECCCE
AVELDERWVIIGPNGAGKTSLLRIAAAADHPSTGVAYVLGERLGRIDISELRARIGLSSS
EEEECCEEEEECCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHH
VLTQRVPSNEVVRDLVVSAGYAVLGRWRERYEGVDYQRAVDMLESMGAEHLADRTFGTLS
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCC
EGERKRVLIARALMTDPELLLLDEPAASLDLGAREELVSRLADLAADAYAPALVLVTHHV
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
EEVPPGFSHCLLLSEAKVVAAGLLSDVLTAENLSTAFGQSIALDVIDGRYFARRVRARAA
HHCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHH
HRRQL
HHCCC
>Mature Secondary Structure 
ATWSRLPGNRRSIAVRHDVRVSQLGPETGSDAADPDLLIDFKDVSLRCEGRVLVGPLDW
CCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCEEEEEECCEEEECCEEEEECCCE
AVELDERWVIIGPNGAGKTSLLRIAAAADHPSTGVAYVLGERLGRIDISELRARIGLSSS
EEEECCEEEEECCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHH
VLTQRVPSNEVVRDLVVSAGYAVLGRWRERYEGVDYQRAVDMLESMGAEHLADRTFGTLS
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCC
EGERKRVLIARALMTDPELLLLDEPAASLDLGAREELVSRLADLAADAYAPALVLVTHHV
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
EEVPPGFSHCLLLSEAKVVAAGLLSDVLTAENLSTAFGQSIALDVIDGRYFARRVRARAA
HHCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHH
HRRQL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11029425; 12397186 [H]