Click here to switch to the map view.

The map label for this gene is ribG [H]

Identifier: 221229684

GI number: 221229684

Start: 672096

End: 673115

Strand: Direct

Name: ribG [H]

Synonym: MLBr_00555

Alternate gene names: 221229684

Gene position: 672096-673115 (Clockwise)

Preceding gene: 221229683

Following gene: 221229687

Centisome position: 20.57

GC content: 64.31

Gene sequence:

>1020_bases
GTGAACGTTCAAACGGTCGACAGCCTCGATGCCGCCATGCGGCTGGCTGTTGAACAGTCTTACCTGGTCAAGGGCGCCAC
CTATCCGAATCCACCGGTGGGTGCGGTTATTGTGGATCCCGATGGGCGGGTTGTTGGCGTGGGCGCCACCGAGCCGGCCG
GCGGCGACCATGCTGAAGTGGTGGCGCTGCGCAGCGCCGGCGTTACAGCGGCCGGTGCCATTGCAGTGGTCACCCTTGAG
CCGTGCAACCACTACGGCAAGACTCCGCCATGCGTGAACGCGCTGCTGGAGGCCAAAGTGGATAAGGTAGCATATGCCAT
CGCCGATCCGAACGCAAGCGCTGGTGGCGGTGCGGCTCGGTTGACGGCAGCCGGCGTGCATGTGCAGTCTGGGGTATTGG
CCGATCTGGTGACCGCCGGACCGCTGCGGGAGTGGCTGCACAAACAGCGGACCGGGCTGCCTCACGTGACGTGGAAGTAT
GCCAGCAGCATAGATGGTCGTAGCGCTGCTGCCGATGGCTCGAGTCGGTGGCTCTCTAGCGAAGCCTCGCGCGCAGACCT
ACATCGTCGCCGCGCCACAGCTGACGCCATTGTGGTTGGCACCGGCACCGTCCTGGCCGATAACCCGACCCTGACGGCCC
GCCTAGCCAATGGTGCGCTGGCTGACCGGCAACCGTTGCGGGTGGTGGTGGGCATGCGGGAAATACCGCTAGAAGCGAAC
GTTCTCAACGACGATTCACCTACTATGGTGATTCGTACCCACGATCCCATGGAGGTCCTCAAGGCGCTTGCAGATCGGAC
AGACGTGCTGCTGGAGGGGGGGCCTACCCTGGCCGGAGCCTTTCTGCGGGCTGGGACGATCAACCGGATCCTGGCCTACG
TCGCGCCGATCTTGCTGGGCGGCCCCGTCACTGCAGTCGACGACGTGGGGGTTCCCAACATTGCGCGGGCGCTACGTTGG
CAGTTCGACGGCATCGACCGGGCTGGCTCGGATTTAGTGATTAGTCTGGTGACGCGTTAG

Upstream 100 bases:

>100_bases
GTTTCGTCGCTGGATCGGCCGTCTATGGCGCAGCCGACCCCAGTGCCGCGGTAGCTGCTTTACGGCGACGGGCTGGTGCC
GTGTCGCCGCATCTACGCCG

Downstream 100 bases:

>100_bases
CGCGTAGCCGTTACGGTGTTGGCATTGGGTCTTTTGTGGTCCGCTACTCGGGGACTTTTGGCTCGCTCGCGTGTTCTTTG
CGGCTGCTGATCAGCAGACC

Product: putative bifunctional riboflavin-specific deaminase/reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNVQTVDSLDAAMRLAVEQSYLVKGATYPNPPVGAVIVDPDGRVVGVGATEPAGGDHAEVVALRSAGVTAAGAIAVVTLE
PCNHYGKTPPCVNALLEAKVDKVAYAIADPNASAGGGAARLTAAGVHVQSGVLADLVTAGPLREWLHKQRTGLPHVTWKY
ASSIDGRSAAADGSSRWLSSEASRADLHRRRATADAIVVGTGTVLADNPTLTARLANGALADRQPLRVVVGMREIPLEAN
VLNDDSPTMVIRTHDPMEVLKALADRTDVLLEGGPTLAGAFLRAGTINRILAYVAPILLGGPVTAVDDVGVPNIARALRW
QFDGIDRAGSDLVISLVTR

Sequences:

>Translated_339_residues
MNVQTVDSLDAAMRLAVEQSYLVKGATYPNPPVGAVIVDPDGRVVGVGATEPAGGDHAEVVALRSAGVTAAGAIAVVTLE
PCNHYGKTPPCVNALLEAKVDKVAYAIADPNASAGGGAARLTAAGVHVQSGVLADLVTAGPLREWLHKQRTGLPHVTWKY
ASSIDGRSAAADGSSRWLSSEASRADLHRRRATADAIVVGTGTVLADNPTLTARLANGALADRQPLRVVVGMREIPLEAN
VLNDDSPTMVIRTHDPMEVLKALADRTDVLLEGGPTLAGAFLRAGTINRILAYVAPILLGGPVTAVDDVGVPNIARALRW
QFDGIDRAGSDLVISLVTR
>Mature_339_residues
MNVQTVDSLDAAMRLAVEQSYLVKGATYPNPPVGAVIVDPDGRVVGVGATEPAGGDHAEVVALRSAGVTAAGAIAVVTLE
PCNHYGKTPPCVNALLEAKVDKVAYAIADPNASAGGGAARLTAAGVHVQSGVLADLVTAGPLREWLHKQRTGLPHVTWKY
ASSIDGRSAAADGSSRWLSSEASRADLHRRRATADAIVVGTGTVLADNPTLTARLANGALADRQPLRVVVGMREIPLEAN
VLNDDSPTMVIRTHDPMEVLKALADRTDVLLEGGPTLAGAFLRAGTINRILAYVAPILLGGPVTAVDDVGVPNIARALRW
QFDGIDRAGSDLVISLVTR

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=350, Percent_Identity=38.2857142857143, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 35147; Mature: 35147

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVQTVDSLDAAMRLAVEQSYLVKGATYPNPPVGAVIVDPDGRVVGVGATEPAGGDHAEV
CCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCEEE
VALRSAGVTAAGAIAVVTLEPCNHYGKTPPCVNALLEAKVDKVAYAIADPNASAGGGAAR
EEEECCCCCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCEE
LTAAGVHVQSGVLADLVTAGPLREWLHKQRTGLPHVTWKYASSIDGRSAAADGSSRWLSS
EEEECEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCHHHHCC
EASRADLHRRRATADAIVVGTGTVLADNPTLTARLANGALADRQPLRVVVGMREIPLEAN
CHHHHHHHHHHCCCCEEEEECCEEEECCCEEEEEECCCCCCCCCCEEEEECHHHCCCEEE
VLNDDSPTMVIRTHDPMEVLKALADRTDVLLEGGPTLAGAFLRAGTINRILAYVAPILLG
EECCCCCEEEEEECCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHC
GPVTAVDDVGVPNIARALRWQFDGIDRAGSDLVISLVTR
CCCCEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MNVQTVDSLDAAMRLAVEQSYLVKGATYPNPPVGAVIVDPDGRVVGVGATEPAGGDHAEV
CCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCEEE
VALRSAGVTAAGAIAVVTLEPCNHYGKTPPCVNALLEAKVDKVAYAIADPNASAGGGAAR
EEEECCCCCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCEE
LTAAGVHVQSGVLADLVTAGPLREWLHKQRTGLPHVTWKYASSIDGRSAAADGSSRWLSS
EEEECEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCHHHHCC
EASRADLHRRRATADAIVVGTGTVLADNPTLTARLANGALADRQPLRVVVGMREIPLEAN
CHHHHHHHHHHCCCCEEEEECCEEEECCCEEEEEECCCCCCCCCCEEEEECHHHCCCEEE
VLNDDSPTMVIRTHDPMEVLKALADRTDVLLEGGPTLAGAFLRAGTINRILAYVAPILLG
EECCCCCEEEEEECCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHC
GPVTAVDDVGVPNIARALRWQFDGIDRAGSDLVISLVTR
CCCCEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]