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The map label for this gene is ribC [H]

Identifier: 221229687

GI number: 221229687

Start: 675561

End: 676184

Strand: Direct

Name: ribC [H]

Synonym: MLBr_00558

Alternate gene names: 221229687

Gene position: 675561-676184 (Clockwise)

Preceding gene: 221229684

Following gene: 221229688

Centisome position: 20.67

GC content: 61.22

Gene sequence:

>624_bases
ATGTTCACCGGAATTGTTGAGGAACTCGGAGAGGTGGTCGGTCGGGACGCCCATGCCGATGCGGCGCGCCTAATCATTCG
CGGTCGCACGGTCACCGCCGACGCTGGCCATGGCGATTCGATCGCGGTTAACGGCGTGTGCCTTACAGTGGTGGAGGTGC
TGCCCGACGGCCAATTCAGTGCTGATGTGATGGCAGAAACGCTCCATCGCTCCAACTTGGGTGAGCTACGAGTCGGCAAT
CGGGTCAACCTGGAGCGCGCTGTGGCTATTAACAGCCGGCTCGGCGGGCATATCGTGCAGGGGCATGTGGACGGCACCGG
CGAGGTGGTGGCTCGCACCCTCTCAGACCACTGGGAGGTGGTGCGGATAGAGGTGCCCCCGGCGGTGGCTCGCTATTTCG
TTGAAAAGGGCTCGATCACCGTCGACGGGATTTCGCTGACGGTCTCCGGGCTCGGTGCTGAACCTCGGGACTGGTTGGAG
GTTTCTTTGATCCCAACGACCCGAGAGCTGACCACCCTTGGCCGTACTCCGTTGGGAACGCAGGTGAACCTTGAAGTGGA
CGTCATCGCCAAATATGTTGAGCGGCTACTCCAGAGCGTTCCTACCGGGGATTTGACTCGATAG

Upstream 100 bases:

>100_bases
AGAGTGTTAAGGGGGTGAACACGGAGCGGCGACGCTGCTTGACAACGGCGTTTGCCGTGCCTGACAGGGGTCGAGCGGAC
GGCCAAACTAGTCTTGTCCC

Downstream 100 bases:

>100_bases
CCTTTCCTGCAGTGGCATGAGCCGCGCAACTGTGCGGCTCATGCCACTTAATCTGCCTTGAAAAGCTGTGGCAATGACCG
TGGCAGCACGGTGGTTCATA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFTGIVEELGEVVGRDAHADAARLIIRGRTVTADAGHGDSIAVNGVCLTVVEVLPDGQFSADVMAETLHRSNLGELRVGN
RVNLERAVAINSRLGGHIVQGHVDGTGEVVARTLSDHWEVVRIEVPPAVARYFVEKGSITVDGISLTVSGLGAEPRDWLE
VSLIPTTRELTTLGRTPLGTQVNLEVDVIAKYVERLLQSVPTGDLTR

Sequences:

>Translated_207_residues
MFTGIVEELGEVVGRDAHADAARLIIRGRTVTADAGHGDSIAVNGVCLTVVEVLPDGQFSADVMAETLHRSNLGELRVGN
RVNLERAVAINSRLGGHIVQGHVDGTGEVVARTLSDHWEVVRIEVPPAVARYFVEKGSITVDGISLTVSGLGAEPRDWLE
VSLIPTTRELTTLGRTPLGTQVNLEVDVIAKYVERLLQSVPTGDLTR
>Mature_207_residues
MFTGIVEELGEVVGRDAHADAARLIIRGRTVTADAGHGDSIAVNGVCLTVVEVLPDGQFSADVMAETLHRSNLGELRVGN
RVNLERAVAINSRLGGHIVQGHVDGTGEVVARTLSDHWEVVRIEVPPAVARYFVEKGSITVDGISLTVSGLGAEPRDWLE
VSLIPTTRELTTLGRTPLGTQVNLEVDVIAKYVERLLQSVPTGDLTR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=203, Percent_Identity=38.423645320197, Blast_Score=113, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=206, Percent_Identity=36.8932038834951, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22159; Mature: 22159

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEELGEVVGRDAHADAARLIIRGRTVTADAGHGDSIAVNGVCLTVVEVLPDGQFS
CCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCEEEECHHHEEHHHHCCCCCCH
ADVMAETLHRSNLGELRVGNRVNLERAVAINSRLGGHIVQGHVDGTGEVVARTLSDHWEV
HHHHHHHHHHCCCCCEECCCCCCHHHEEEECCCCCCEEEEEEECCHHHHHHHHHCCCEEE
VRIEVPPAVARYFVEKGSITVDGISLTVSGLGAEPRDWLEVSLIPTTRELTTLGRTPLGT
EEEECCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCEEEEECCCCHHHHHCCCCCCCC
QVNLEVDVIAKYVERLLQSVPTGDLTR
EEEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFTGIVEELGEVVGRDAHADAARLIIRGRTVTADAGHGDSIAVNGVCLTVVEVLPDGQFS
CCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCEEEECHHHEEHHHHCCCCCCH
ADVMAETLHRSNLGELRVGNRVNLERAVAINSRLGGHIVQGHVDGTGEVVARTLSDHWEV
HHHHHHHHHHCCCCCEECCCCCCHHHEEEECCCCCCEEEEEEECCHHHHHHHHHCCCEEE
VRIEVPPAVARYFVEKGSITVDGISLTVSGLGAEPRDWLEVSLIPTTRELTTLGRTPLGT
EEEECCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCEEEEECCCCHHHHHCCCCCCCC
QVNLEVDVIAKYVERLLQSVPTGDLTR
EEEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]