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The map label for this gene is rpe

Identifier: 221229683

GI number: 221229683

Start: 671425

End: 672099

Strand: Direct

Name: rpe

Synonym: MLBr_00554

Alternate gene names: 221229683

Gene position: 671425-672099 (Clockwise)

Preceding gene: 221229682

Following gene: 221229684

Centisome position: 20.54

GC content: 60.89

Gene sequence:

>675_bases
ATGGGACCCCTGATCGCCCCGTCGATCCTGGCCGCTGATTTCGCCCGGCTCACCGACGAAGCCGCCGTTGTGGCCAGCGC
TGATTGGTTGCATGTCGATGTGATGGACGGCCACTTCGTGCCAAACCTGACTATCGGACTGCCGGTGGTGCAGAGTCTGC
TAGCTGCCAGCGACATCCCGATGGATTGTCATCTAATGATCGACAACCCAGACAGGTGGGCACCGCCGTACGCCGAAGCC
GGCGCCTATAACGTCACCTTTCACGCTGAGGCTACCGACAATCCGGTAGGAGTAGCCCACGACATCCGGACCGCTGGCGC
TAAAGCGGGGATCGGAGTTAAGCCTGGGACACCGCTGAATCCCTACTTGGACATCCTGCCGCACTTCGACACCCTGCTCA
TCATGTCGGTGGAACCTGGCTTCGGAGGCCAGGCATTTATCCCCGAAGTGCTGAGTAAGGTGCGTACAGTACGCAAGATG
GTTGATGCGGGTGAGTTGACGATCCTGGTCGAGATCGATGGCGGCATCAATGCGGACACTATTGAGCAAGCTGCCGAAGC
CGGTGTGGACTGTTTCGTCGCTGGATCGGCCGTCTATGGCGCAGCCGACCCCAGTGCCGCGGTAGCTGCTTTACGGCGAC
GGGCTGGTGCCGTGTCGCCGCATCTACGCCGGTGA

Upstream 100 bases:

>100_bases
ACCGGCACGGCACTGACGCCATGTTCGCAGCTGTACTGTGCCGCCTGCTGTGATCCGCGTAGCGGGGTTCAGTAGTCTGC
GGCTCATGCCTGGCAACAAC

Downstream 100 bases:

>100_bases
ACGTTCAAACGGTCGACAGCCTCGATGCCGCCATGCGGCTGGCTGTTGAACAGTCTTACCTGGTCAAGGGCGCCACCTAT
CCGAATCCACCGGTGGGTGC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MGPLIAPSILAADFARLTDEAAVVASADWLHVDVMDGHFVPNLTIGLPVVQSLLAASDIPMDCHLMIDNPDRWAPPYAEA
GAYNVTFHAEATDNPVGVAHDIRTAGAKAGIGVKPGTPLNPYLDILPHFDTLLIMSVEPGFGGQAFIPEVLSKVRTVRKM
VDAGELTILVEIDGGINADTIEQAAEAGVDCFVAGSAVYGAADPSAAVAALRRRAGAVSPHLRR

Sequences:

>Translated_224_residues
MGPLIAPSILAADFARLTDEAAVVASADWLHVDVMDGHFVPNLTIGLPVVQSLLAASDIPMDCHLMIDNPDRWAPPYAEA
GAYNVTFHAEATDNPVGVAHDIRTAGAKAGIGVKPGTPLNPYLDILPHFDTLLIMSVEPGFGGQAFIPEVLSKVRTVRKM
VDAGELTILVEIDGGINADTIEQAAEAGVDCFVAGSAVYGAADPSAAVAALRRRAGAVSPHLRR
>Mature_223_residues
GPLIAPSILAADFARLTDEAAVVASADWLHVDVMDGHFVPNLTIGLPVVQSLLAASDIPMDCHLMIDNPDRWAPPYAEAG
AYNVTFHAEATDNPVGVAHDIRTAGAKAGIGVKPGTPLNPYLDILPHFDTLLIMSVEPGFGGQAFIPEVLSKVRTVRKMV
DAGELTILVEIDGGINADTIEQAAEAGVDCFVAGSAVYGAADPSAAVAALRRRAGAVSPHLRR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family

Homologues:

Organism=Homo sapiens, GI40385883, Length=216, Percent_Identity=43.0555555555556, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI219879828, Length=216, Percent_Identity=41.6666666666667, Blast_Score=167, Evalue=5e-42,
Organism=Homo sapiens, GI24307923, Length=167, Percent_Identity=35.9281437125749, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1789788, Length=220, Percent_Identity=46.3636363636364, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1790523, Length=195, Percent_Identity=34.3589743589744, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1790754, Length=210, Percent_Identity=30.4761904761905, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17552948, Length=218, Percent_Identity=45.8715596330275, Blast_Score=192, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6322341, Length=236, Percent_Identity=43.2203389830509, Blast_Score=198, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=41.2322274881517, Blast_Score=164, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPE_MYCLE (Q9CCP9)

Other databases:

- EMBL:   AL583918
- PIR:   B86978
- RefSeq:   NP_301468.1
- ProteinModelPortal:   Q9CCP9
- SMR:   Q9CCP9
- EnsemblBacteria:   EBMYCT00000028342
- GeneID:   909330
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0554
- NMPDR:   fig|272631.1.peg.340
- Leproma:   ML0554
- GeneTree:   EBGT00050000016437
- HOGENOM:   HBG571751
- OMA:   HIDRTLQ
- ProtClustDB:   PRK05581
- BioCyc:   MLEP272631:ML0554-MONOMER
- BRENDA:   5.1.3.1
- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR11749
- PIRSF:   PIRSF001461
- TIGRFAMs:   TIGR01163

Pfam domain/function: PF00834 Ribul_P_3_epim; SSF51366 RibP_bind_barrel

EC number: =5.1.3.1

Molecular weight: Translated: 23408; Mature: 23277

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLIAPSILAADFARLTDEAAVVASADWLHVDVMDGHFVPNLTIGLPVVQSLLAASDIP
CCCCCCHHHHHHHHHHHCCCHHEEEECCEEEEEEECCCCCCCCEECHHHHHHHHHHCCCC
MDCHLMIDNPDRWAPPYAEAGAYNVTFHAEATDNPVGVAHDIRTAGAKAGIGVKPGTPLN
CEEEEEECCCCCCCCCCHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
PYLDILPHFDTLLIMSVEPGFGGQAFIPEVLSKVRTVRKMVDAGELTILVEIDGGINADT
HHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
IEQAAEAGVDCFVAGSAVYGAADPSAAVAALRRRAGAVSPHLRR
HHHHHHCCCEEEEECCEEECCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GPLIAPSILAADFARLTDEAAVVASADWLHVDVMDGHFVPNLTIGLPVVQSLLAASDIP
CCCCCHHHHHHHHHHHCCCHHEEEECCEEEEEEECCCCCCCCEECHHHHHHHHHHCCCC
MDCHLMIDNPDRWAPPYAEAGAYNVTFHAEATDNPVGVAHDIRTAGAKAGIGVKPGTPLN
CEEEEEECCCCCCCCCCHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
PYLDILPHFDTLLIMSVEPGFGGQAFIPEVLSKVRTVRKMVDAGELTILVEIDGGINADT
HHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
IEQAAEAGVDCFVAGSAVYGAADPSAAVAALRRRAGAVSPHLRR
HHHHHHCCCEEEEECCEEECCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002