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The map label for this gene is secD [H]

Identifier: 221229642

GI number: 221229642

Start: 590045

End: 591838

Strand: Direct

Name: secD [H]

Synonym: MLBr_00487

Alternate gene names: 221229642

Gene position: 590045-591838 (Clockwise)

Preceding gene: 221229641

Following gene: 221229643

Centisome position: 18.05

GC content: 59.64

Gene sequence:

>1794_bases
GTGTCTTGTGTGAAGGGCCTAGTGATGCGACACGTAGGCTCTGTCGGGAAAAACCGATTTCGAGGAGATACAAGGAACGT
GGCATCGTCTTCGGCGCCAGTGCATTTTGGCCGCTACCTGTCGATGTTTCTGGTGTTATTCATCGGGGTCTATCTGTTAG
CGTTTCTCACCGGAGACAAGCGGGTCGTTCCCAGGCTCGGCATAGACCTCCAAGGCGGCACCCGCGTAACGTTGACCGCG
CGCACGCCCGACGGCTCGCGCCCCAGCCGGGAGGCGTTGTCACAGGCGCAGCAGATCATCAGCTCCCGGGTTAACGGGCT
CGGAGTATCGGGTTCGGAAGTGGTCGTCGATGGCGACAACCTGGTCATCACTGTGCCCGGCAACGACGGCAACGAGGCCC
GCAACCTGGGCCAGACTGCGCGTCTGTACATCCGGCCGGTGCTTAACTCGCTACCCGTGCAACGTGGTCAAGACCCCAAG
CCGGGTTCCCCTGCCGGCACGTTGCCCAATTTCGCGCCGATGCCGCCCGACCACCCAGGCGCGCAACCACGCCCCTACCT
GCAAGATCCGACGTCATCACCTAGCTCAGATCCGATGCCAAGTCCAGTGCCAACCGGAGCGGCACTACCGGGTGAGGTTC
CCTCGGTTGAGCAGCCCGCGCCACCGGATCCGCGTAAGGATCTAGCTGAACGCATTGCCGAGGAGAAGAAGTGGCGGCAA
AGCACCAAACAGAGTATTCAGTTCCTCGCATTGCAGTTCGAATCCACCCACTGCGACAAAGACGACATTCTGGCCGGCAA
TGACGACCCGAATCTGCCTCTGGCGACCTGCTCGACCGACCATAATATGGCGTATTTGTTAGCGCCATCGATCATCAGCG
GCGACCAGATCCAAAACTCCACGTCCGGCATGAACCAGCGTGGGGTCGGCTACGTCGTCGATCTGCAGTTCAAGTCTGCG
GCCGCAGATGTCTGGGCTGACTTCACCGCCGCCCACATCGGTACTCAGACCGCTTTCACCCTGGACTCCGAGGTGGTCAG
CGTCCCGGTAATCAACGAGGCAATTTTGGGCGGGCGTACCCAGATCAGTGGTGGAGATCCGCCGTTCACCGCCGCAACCG
CGCGCCAGCTGGCCAACGTTTTGAAATACGGATCGCTGCCGCTATCTTTCGAGCCGTCGGAAGCTCAAACAGTTTCGGCG
ACTTTGGGGTTGACATCGTTACGGGCGGGTCTGATCGCAGGTGCGATCGGCCTGAGCCTAGTGTTGCTGTACTCGTTGCT
ATATTACCGGGTACTTGGATTGCTCACCGCGTTTTCGCTTTTCTGTTCCGGCACAATAATTTTTGCGATCTTGGTGCTCT
TGGGTCGATATATCAATTATACTTTGGACCTTGCGGGTATCGCGGGTCTGATCATCGGTATCGGCACCACTGCCGACTCC
TTCGTGGTGTTTTTCGAGCGGATCAAAGATGAGATCCGCGAAGGCCGTTCGTTCCGGTCGGCTGTTCCTCGTGGCTGGGT
GCGTGCCCGCAAGACGATCGTGTCCGGCAACGCTGTCACCTTCCTGGCGGCTGCTGTGCTGCACTTCCTGGCGATTGGCC
AAGTAAAGGGATTTGCTTTCACCCTCGGCCTTACCACGATCCTGGACCTGGTGGTGGTGTTCCTGGTGACCTGGCCGCTG
GTGTACTTGGCTTCCAAGTCTCCGTTGCTGGCAAGGCCGGCATACAACGGCTTGGGCGCCGTTCAACAGGTTGCCCGCGA
ACGACGGGCTTCCGCCAAGACAGGACGGGGGTAG

Upstream 100 bases:

>100_bases
GGCCGAACCGGGGGATTTCGTGTACTGCGATGAGCTAGAAGAGTCCGACGGCTCCAGCTAACGTCGAGGAACGAGTGATG
AGGGATTCCTGACGGCGCTT

Downstream 100 bases:

>100_bases
CGCGATGGTCTCCAGAGCCAAAGTCGGGGCCGAGACCACCAAGGGTATCGACGAACCAGACCGAAATGACAACACCGACG
ACAATGGCGCCGGTGCGGTC

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MSCVKGLVMRHVGSVGKNRFRGDTRNVASSSAPVHFGRYLSMFLVLFIGVYLLAFLTGDKRVVPRLGIDLQGGTRVTLTA
RTPDGSRPSREALSQAQQIISSRVNGLGVSGSEVVVDGDNLVITVPGNDGNEARNLGQTARLYIRPVLNSLPVQRGQDPK
PGSPAGTLPNFAPMPPDHPGAQPRPYLQDPTSSPSSDPMPSPVPTGAALPGEVPSVEQPAPPDPRKDLAERIAEEKKWRQ
STKQSIQFLALQFESTHCDKDDILAGNDDPNLPLATCSTDHNMAYLLAPSIISGDQIQNSTSGMNQRGVGYVVDLQFKSA
AADVWADFTAAHIGTQTAFTLDSEVVSVPVINEAILGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSA
TLGLTSLRAGLIAGAIGLSLVLLYSLLYYRVLGLLTAFSLFCSGTIIFAILVLLGRYINYTLDLAGIAGLIIGIGTTADS
FVVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLHFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPL
VYLASKSPLLARPAYNGLGAVQQVARERRASAKTGRG

Sequences:

>Translated_597_residues
MSCVKGLVMRHVGSVGKNRFRGDTRNVASSSAPVHFGRYLSMFLVLFIGVYLLAFLTGDKRVVPRLGIDLQGGTRVTLTA
RTPDGSRPSREALSQAQQIISSRVNGLGVSGSEVVVDGDNLVITVPGNDGNEARNLGQTARLYIRPVLNSLPVQRGQDPK
PGSPAGTLPNFAPMPPDHPGAQPRPYLQDPTSSPSSDPMPSPVPTGAALPGEVPSVEQPAPPDPRKDLAERIAEEKKWRQ
STKQSIQFLALQFESTHCDKDDILAGNDDPNLPLATCSTDHNMAYLLAPSIISGDQIQNSTSGMNQRGVGYVVDLQFKSA
AADVWADFTAAHIGTQTAFTLDSEVVSVPVINEAILGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSA
TLGLTSLRAGLIAGAIGLSLVLLYSLLYYRVLGLLTAFSLFCSGTIIFAILVLLGRYINYTLDLAGIAGLIIGIGTTADS
FVVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLHFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPL
VYLASKSPLLARPAYNGLGAVQQVARERRASAKTGRG
>Mature_596_residues
SCVKGLVMRHVGSVGKNRFRGDTRNVASSSAPVHFGRYLSMFLVLFIGVYLLAFLTGDKRVVPRLGIDLQGGTRVTLTAR
TPDGSRPSREALSQAQQIISSRVNGLGVSGSEVVVDGDNLVITVPGNDGNEARNLGQTARLYIRPVLNSLPVQRGQDPKP
GSPAGTLPNFAPMPPDHPGAQPRPYLQDPTSSPSSDPMPSPVPTGAALPGEVPSVEQPAPPDPRKDLAERIAEEKKWRQS
TKQSIQFLALQFESTHCDKDDILAGNDDPNLPLATCSTDHNMAYLLAPSIISGDQIQNSTSGMNQRGVGYVVDLQFKSAA
ADVWADFTAAHIGTQTAFTLDSEVVSVPVINEAILGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSAT
LGLTSLRAGLIAGAIGLSLVLLYSLLYYRVLGLLTAFSLFCSGTIIFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSF
VVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLHFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLV
YLASKSPLLARPAYNGLGAVQQVARERRASAKTGRG

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=368, Percent_Identity=26.0869565217391, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 63575; Mature: 63443

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCVKGLVMRHVGSVGKNRFRGDTRNVASSSAPVHFGRYLSMFLVLFIGVYLLAFLTGDK
CHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVVPRLGIDLQGGTRVTLTARTPDGSRPSREALSQAQQIISSRVNGLGVSGSEVVVDGDN
EECCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
LVITVPGNDGNEARNLGQTARLYIRPVLNSLPVQRGQDPKPGSPAGTLPNFAPMPPDHPG
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AQPRPYLQDPTSSPSSDPMPSPVPTGAALPGEVPSVEQPAPPDPRKDLAERIAEEKKWRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
STKQSIQFLALQFESTHCDKDDILAGNDDPNLPLATCSTDHNMAYLLAPSIISGDQIQNS
HHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCHHCCCHHCCC
TSGMNQRGVGYVVDLQFKSAAADVWADFTAAHIGTQTAFTLDSEVVSVPVINEAILGGRT
CCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHCCCC
QISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLTSLRAGLIAGAIGLSL
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLLYSLLYYRVLGLLTAFSLFCSGTIIFAILVLLGRYINYTLDLAGIAGLIIGIGTTADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
FVVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLHFLAIGQVKGFAF
HHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHH
TLGLTTILDLVVVFLVTWPLVYLASKSPLLARPAYNGLGAVQQVARERRASAKTGRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SCVKGLVMRHVGSVGKNRFRGDTRNVASSSAPVHFGRYLSMFLVLFIGVYLLAFLTGDK
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVVPRLGIDLQGGTRVTLTARTPDGSRPSREALSQAQQIISSRVNGLGVSGSEVVVDGDN
EECCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
LVITVPGNDGNEARNLGQTARLYIRPVLNSLPVQRGQDPKPGSPAGTLPNFAPMPPDHPG
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AQPRPYLQDPTSSPSSDPMPSPVPTGAALPGEVPSVEQPAPPDPRKDLAERIAEEKKWRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
STKQSIQFLALQFESTHCDKDDILAGNDDPNLPLATCSTDHNMAYLLAPSIISGDQIQNS
HHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCHHCCCHHCCC
TSGMNQRGVGYVVDLQFKSAAADVWADFTAAHIGTQTAFTLDSEVVSVPVINEAILGGRT
CCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHCCCC
QISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLTSLRAGLIAGAIGLSL
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLLYSLLYYRVLGLLTAFSLFCSGTIIFAILVLLGRYINYTLDLAGIAGLIIGIGTTADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
FVVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLHFLAIGQVKGFAF
HHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHH
TLGLTTILDLVVVFLVTWPLVYLASKSPLLARPAYNGLGAVQQVARERRASAKTGRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]