| Definition | Halothermothrix orenii H 168 chromosome, complete genome. |
|---|---|
| Accession | NC_011899 |
| Length | 2,578,146 |
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The map label for this gene is mtlR [H]
Identifier: 220932849
GI number: 220932849
Start: 2173706
End: 2175931
Strand: Reverse
Name: mtlR [H]
Synonym: Hore_20170
Alternate gene names: 220932849
Gene position: 2175931-2173706 (Counterclockwise)
Preceding gene: 220932850
Following gene: 220932848
Centisome position: 84.4
GC content: 30.55
Gene sequence:
>2226_bases TTGAGTTTAAAACCCCGGGTTTGTCAATTATTGAAATATTTAATTGACCAGGAGAAAGCTGTCTCTATTAAACAATTGGC TGATAGATTTAATGTTAGTAGTAGAACGATCAGGTATGATCTAGATGATATTGAATCTAGTATCTCTTCCTATGATGCTA AATTAATAAGAAAAACACGAATTGGGGTTTATTTAGAGGGAAAAGAAGAAGAGTTAAATAAGATACAAGAAGAATTAGCT AATCTTTATGGCCTTGAAAGAATTTTATCTCCTAAAGAGCGTCAGCATCTAATTTTATTTAGACTATTTCAGGCTAATGA ACCGATTATTATCAAAGAATTAGAAATAATGTTACGCATCAGTAAGTCAACAATAATTAAAGATTTAGATGAAGTTGAAA ACTGGTTATCAAAGCACAATTTAATTCTTATTAGAAAGACCAATTATGGTTTAGAAATAAAAGGTGACGAGATAGATATT AGACATGCCATGATGAATGTTTTAGAAGAAACAGCAAATGAAAAAGAATTAGTTGGATTTTTACGACAAATTCAGAAAAA AGCATTGGAAGAAAGAAATTTAGAGCCGGGGTTTTTTAAAGAATTTGATAAATTAGTATCTGGTATTGATTTGACCAAGA TTGAAAGTGTAATTTCTTTTGCCGAAAAGCAATTAGGATTTCAATTTGCTGATGAAGCGTATGCTAGTTTGTTAGTTCAT TTAGCTTTAGCAATAAGCAGATTATTAGAAGGAAAAGATATTCAGCTACCCGAGGAACGATTAAAGGTTATTAAAAAAAG TGATGAATATAAGATAGCCAAGAAGATAGGAAAGATCATGGAGCAAATTTTTGACATAAGCATTCCAGATTCGGAGATAG GTTATGTTACCTTACATTTAATGGGGGCTAAATTATGGCAAAAGATAGGTGATGACGATTATAAAAAACTTATCAACCAG GATTTAGACCAGGAGCTGATTATTTTAACTAAAGAAATGGTTAAGGTAGCTGAAGACTATTTAGGGGTTAAGTTAATTGA TGATACTCAATTAATAATTGGTCTGGCGTTACATTTAAAACCAACTATTAATCGTATAAAATATGACCTACCATTAAAAA ATCCCTTACTGTTAGATGTTAAAAGCAGGTACGGGGAAATATTTAAAGCAGCTAAAAGGGCAGCTAAGATATTACAGAGC AAGTTGCAAAAATCAATTAGTTCAGATGAAATTGGGTATATTACCCTTCATCTTGGAGCTGCTTTAGAGAGGAGTAAATC TAGCAGAAAATTAAGGGTAGTCTTAGTTTGTTCAAGTGGAGTAGGAACAACTAACTTGTTATCTTCTAGATTAAGTAAAG AATTTTCTGAGATCAAAATTTGTAATGTTGTTTCTGTTATTCAATTAGAGAATAATGAAGTTGATTTAAAAAACATTGAT TTAATTATTACAACTATCCCGTTAGATATTGATGATATTTTAGTATTACAGGTTAATCCTCTATTAAGCCAGAAGGATAA GAAAAATGTTAAAGCTATTATTCAAAGTAAGCGAGATATTTTTGATTCCACTGAAATTAAAGAGGACTCTGAATCTATAA CAGATTATTCCTTTGATATTGAAGAAGTAATTGAGGTTATAGAGCAAGAAGCAATTGTAGGAGATAAAGATAGCCTAAAA AAAGATTTAAGAGATTTTTTTGCTTCTAAAGGAGTTAAAGTTTTAGATAAAATAGATGATACAGCTGACAGGCAAAGTAT AGAAGAGAGTGGTAAAGGACTATTAGAATTGTTAACTGAAAATAATATAGCAGTAATTGATAAGGTAGATAATTGGAGAA CAGGAGTTAGAGTAGCAGCAAAGCCTTTAGTAGATCAGGGTCATATATTAGAAGAATATGTTGAGCGAACGATAGAAGTC ATTGAACAAAAAGGTGCTTACGTAGTAATATCCCCTCATATTAGTTTAATACATGCTAGACCTGAAGATGGAGTTGTAAA AAAGAGTATGGGATTAGGGATTATAAAAGAGGGAGTTAATTTTGGTCATGATTATGATCCTGTTCATTTAATTTTTACAT TAGCTCCTATAGATGAAGTTTCCCATCTCTCTGCTTTATCTGAACTTTTGAAATTAATTAATGAATATGGTTTTGTAGAG AAAATGCTGACAGTAGATAACCAACATGATGTTTTAATTAAGATAGAAGAAATGTTAATTAAGTAA
Upstream 100 bases:
>100_bases ATTGCTAAGAATATTACAAATAAATTTGTTAAAAATGTTTTAAAATTCTAGCAATTAATTACAAGAGCTTTTCCCTTTAA ATAAGTAAGGAGGCAAAAAG
Downstream 100 bases:
>100_bases TAATAATCTTTCACTAGCGTTGCATCGTGTTTTATTTACTAAAATATTTTTATTAATTTTATATAAGAGGTGAGTTTAAT GGAAAAAAATTCAGTTGTTA
Product: transcriptional antiterminator, BglG
Products: NA
Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 741; Mature: 740
Protein sequence:
>741_residues MSLKPRVCQLLKYLIDQEKAVSIKQLADRFNVSSRTIRYDLDDIESSISSYDAKLIRKTRIGVYLEGKEEELNKIQEELA NLYGLERILSPKERQHLILFRLFQANEPIIIKELEIMLRISKSTIIKDLDEVENWLSKHNLILIRKTNYGLEIKGDEIDI RHAMMNVLEETANEKELVGFLRQIQKKALEERNLEPGFFKEFDKLVSGIDLTKIESVISFAEKQLGFQFADEAYASLLVH LALAISRLLEGKDIQLPEERLKVIKKSDEYKIAKKIGKIMEQIFDISIPDSEIGYVTLHLMGAKLWQKIGDDDYKKLINQ DLDQELIILTKEMVKVAEDYLGVKLIDDTQLIIGLALHLKPTINRIKYDLPLKNPLLLDVKSRYGEIFKAAKRAAKILQS KLQKSISSDEIGYITLHLGAALERSKSSRKLRVVLVCSSGVGTTNLLSSRLSKEFSEIKICNVVSVIQLENNEVDLKNID LIITTIPLDIDDILVLQVNPLLSQKDKKNVKAIIQSKRDIFDSTEIKEDSESITDYSFDIEEVIEVIEQEAIVGDKDSLK KDLRDFFASKGVKVLDKIDDTADRQSIEESGKGLLELLTENNIAVIDKVDNWRTGVRVAAKPLVDQGHILEEYVERTIEV IEQKGAYVVISPHISLIHARPEDGVVKKSMGLGIIKEGVNFGHDYDPVHLIFTLAPIDEVSHLSALSELLKLINEYGFVE KMLTVDNQHDVLIKIEEMLIK
Sequences:
>Translated_741_residues MSLKPRVCQLLKYLIDQEKAVSIKQLADRFNVSSRTIRYDLDDIESSISSYDAKLIRKTRIGVYLEGKEEELNKIQEELA NLYGLERILSPKERQHLILFRLFQANEPIIIKELEIMLRISKSTIIKDLDEVENWLSKHNLILIRKTNYGLEIKGDEIDI RHAMMNVLEETANEKELVGFLRQIQKKALEERNLEPGFFKEFDKLVSGIDLTKIESVISFAEKQLGFQFADEAYASLLVH LALAISRLLEGKDIQLPEERLKVIKKSDEYKIAKKIGKIMEQIFDISIPDSEIGYVTLHLMGAKLWQKIGDDDYKKLINQ DLDQELIILTKEMVKVAEDYLGVKLIDDTQLIIGLALHLKPTINRIKYDLPLKNPLLLDVKSRYGEIFKAAKRAAKILQS KLQKSISSDEIGYITLHLGAALERSKSSRKLRVVLVCSSGVGTTNLLSSRLSKEFSEIKICNVVSVIQLENNEVDLKNID LIITTIPLDIDDILVLQVNPLLSQKDKKNVKAIIQSKRDIFDSTEIKEDSESITDYSFDIEEVIEVIEQEAIVGDKDSLK KDLRDFFASKGVKVLDKIDDTADRQSIEESGKGLLELLTENNIAVIDKVDNWRTGVRVAAKPLVDQGHILEEYVERTIEV IEQKGAYVVISPHISLIHARPEDGVVKKSMGLGIIKEGVNFGHDYDPVHLIFTLAPIDEVSHLSALSELLKLINEYGFVE KMLTVDNQHDVLIKIEEMLIK >Mature_740_residues SLKPRVCQLLKYLIDQEKAVSIKQLADRFNVSSRTIRYDLDDIESSISSYDAKLIRKTRIGVYLEGKEEELNKIQEELAN LYGLERILSPKERQHLILFRLFQANEPIIIKELEIMLRISKSTIIKDLDEVENWLSKHNLILIRKTNYGLEIKGDEIDIR HAMMNVLEETANEKELVGFLRQIQKKALEERNLEPGFFKEFDKLVSGIDLTKIESVISFAEKQLGFQFADEAYASLLVHL ALAISRLLEGKDIQLPEERLKVIKKSDEYKIAKKIGKIMEQIFDISIPDSEIGYVTLHLMGAKLWQKIGDDDYKKLINQD LDQELIILTKEMVKVAEDYLGVKLIDDTQLIIGLALHLKPTINRIKYDLPLKNPLLLDVKSRYGEIFKAAKRAAKILQSK LQKSISSDEIGYITLHLGAALERSKSSRKLRVVLVCSSGVGTTNLLSSRLSKEFSEIKICNVVSVIQLENNEVDLKNIDL IITTIPLDIDDILVLQVNPLLSQKDKKNVKAIIQSKRDIFDSTEIKEDSESITDYSFDIEEVIEVIEQEAIVGDKDSLKK DLRDFFASKGVKVLDKIDDTADRQSIEESGKGLLELLTENNIAVIDKVDNWRTGVRVAAKPLVDQGHILEEYVERTIEVI EQKGAYVVISPHISLIHARPEDGVVKKSMGLGIIKEGVNFGHDYDPVHLIFTLAPIDEVSHLSALSELLKLINEYGFVEK MLTVDNQHDVLIKIEEMLIK
Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
Organism=Escherichia coli, GI1789302, Length=113, Percent_Identity=29.2035398230088, Blast_Score=74, Evalue=4e-14, Organism=Escherichia coli, GI2367359, Length=111, Percent_Identity=32.4324324324324, Blast_Score=64, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 84314; Mature: 84183
Theoretical pI: Translated: 5.21; Mature: 5.21
Prosite motif: PS51000 HTH_DEOR_2 ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLKPRVCQLLKYLIDQEKAVSIKQLADRFNVSSRTIRYDLDDIESSISSYDAKLIRKTR CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHH IGVYLEGKEEELNKIQEELANLYGLERILSPKERQHLILFRLFQANEPIIIKELEIMLRI CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHCCCCEEHHHHHHHHHH SKSTIIKDLDEVENWLSKHNLILIRKTNYGLEIKGDEIDIRHAMMNVLEETANEKELVGF HHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHH LRQIQKKALEERNLEPGFFKEFDKLVSGIDLTKIESVISFAEKQLGFQFADEAYASLLVH HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH LALAISRLLEGKDIQLPEERLKVIKKSDEYKIAKKIGKIMEQIFDISIPDSEIGYVTLHL HHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHH MGAKLWQKIGDDDYKKLINQDLDQELIILTKEMVKVAEDYLGVKLIDDTQLIIGLALHLK HHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHCC PTINRIKYDLPLKNPLLLDVKSRYGEIFKAAKRAAKILQSKLQKSISSDEIGYITLHLGA HHHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECH ALERSKSSRKLRVVLVCSSGVGTTNLLSSRLSKEFSEIKICNVVSVIQLENNEVDLKNID HHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEECC LIITTIPLDIDDILVLQVNPLLSQKDKKNVKAIIQSKRDIFDSTEIKEDSESITDYSFDI EEEEEECCCCCCEEEEEECHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCH EEVIEVIEQEAIVGDKDSLKKDLRDFFASKGVKVLDKIDDTADRQSIEESGKGLLELLTE HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCHHHHHHHC NNIAVIDKVDNWRTGVRVAAKPLVDQGHILEEYVERTIEVIEQKGAYVVISPHISLIHAR CCEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEC PEDGVVKKSMGLGIIKEGVNFGHDYDPVHLIFTLAPIDEVSHLSALSELLKLINEYGFVE CCCCCHHHHCCCHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH KMLTVDNQHDVLIKIEEMLIK HHHHCCCCCCEEEEHHHHHCC >Mature Secondary Structure SLKPRVCQLLKYLIDQEKAVSIKQLADRFNVSSRTIRYDLDDIESSISSYDAKLIRKTR CCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHH IGVYLEGKEEELNKIQEELANLYGLERILSPKERQHLILFRLFQANEPIIIKELEIMLRI CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHCCCCEEHHHHHHHHHH SKSTIIKDLDEVENWLSKHNLILIRKTNYGLEIKGDEIDIRHAMMNVLEETANEKELVGF HHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHH LRQIQKKALEERNLEPGFFKEFDKLVSGIDLTKIESVISFAEKQLGFQFADEAYASLLVH HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH LALAISRLLEGKDIQLPEERLKVIKKSDEYKIAKKIGKIMEQIFDISIPDSEIGYVTLHL HHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHH MGAKLWQKIGDDDYKKLINQDLDQELIILTKEMVKVAEDYLGVKLIDDTQLIIGLALHLK HHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHCC PTINRIKYDLPLKNPLLLDVKSRYGEIFKAAKRAAKILQSKLQKSISSDEIGYITLHLGA HHHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECH ALERSKSSRKLRVVLVCSSGVGTTNLLSSRLSKEFSEIKICNVVSVIQLENNEVDLKNID HHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEECC LIITTIPLDIDDILVLQVNPLLSQKDKKNVKAIIQSKRDIFDSTEIKEDSESITDYSFDI EEEEEECCCCCCEEEEEECHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCH EEVIEVIEQEAIVGDKDSLKKDLRDFFASKGVKVLDKIDDTADRQSIEESGKGLLELLTE HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCHHHHHHHC NNIAVIDKVDNWRTGVRVAAKPLVDQGHILEEYVERTIEVIEQKGAYVVISPHISLIHAR CCEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEC PEDGVVKKSMGLGIIKEGVNFGHDYDPVHLIFTLAPIDEVSHLSALSELLKLINEYGFVE CCCCCHHHHCCCHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH KMLTVDNQHDVLIKIEEMLIK HHHHCCCCCCEEEEHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]