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The map label for this gene is xylR [H]

Identifier: 220932788

GI number: 220932788

Start: 2095419

End: 2096594

Strand: Reverse

Name: xylR [H]

Synonym: Hore_19540

Alternate gene names: 220932788

Gene position: 2096594-2095419 (Counterclockwise)

Preceding gene: 220932789

Following gene: 220932787

Centisome position: 81.32

GC content: 40.14

Gene sequence:

>1176_bases
ATGAATGTTAAAGTGGGAAACTCCACCTTTATAAAAAATTTAAACCAGAAAAGGATTTTTAAGCTGATTCATAAAGAGGG
ACCAATAACCCGGAAAGAGTTAGCCGATAATACTGATTACAGTGCCGGTACTATTTCCAACCATGTTAAGGCCCTGATTG
ATCAGGGGTTTGTTATTGAAACTGAAAAGGGATATTCCAGTGGTGGAAGAAAACCGGTCTATCTTACCGTTAACCCCGAT
AAGGGATATATAATAAGTGTTGAAGTAGAAGTGACCCGGGTTAAAATTGTATTATTTAATTTAAAAATTAAGGTTGTGGC
CAAAACTGTATTTCCAATAAACGGGCCCGCCCAGGCGAAGGAGACCATTTCTCAAATTTTTTCAGAAATTGAGAAAATCC
TGTCAGAAAGGGAAATAAAGCCAGATAAAATACTCGGTATCGGGGTGGCTGTTCCCGGCCTGATTGATAAAGAAGAAGGT
TTGCTGGAGTTTGCTCCCAATTTAGGCTGGAGTAAAGTGCCTATTGTAAAATATTTTGAGGATAAATATGGGGTTCCGGT
TGTTCTTGAAAATGAAGCCAATGCAGCAGCAGTAGGTGAAAAGGAGTTTGTTTATCCCGATATTAAAGATATGGTTTATG
TATCGATTAATGAAGGTATCGGGTGTGGGCTTATCTTTAATGGACGGCTTTACCGGGGAGCCGGAGGTAATGCCGGTGAG
TTTGGACATATTATCATTGATAGTGATGGACCATTATGCCACTGTGGTAATAGTGGGTGCTGGGAAACCCTGGCTTCTGA
AAACCATATCCAGAAGGAATATCAGGAGTTGACCGGGGAAGAAAATGTGGAAAAGAACGAAATTTACCGGAAAGCCATTG
AAGGTGAGGATAGGGCCTTAAGTGTGGTTAAACAGGCTGCTCATAATATCGGCCTGGGCCTTGCCAATATAGTTAACAGC
CTCAGCCCGAGGTTGATTGTCCTTGGAGGGGGTATAATTGAAGCCGACACCTTAATTATAGATACTGTACAAAGTATTCT
GAAAGAAAAATGCCTGCTCCTTTCTTATGATAAGGTTGATATTGAGTTTACCAGGCTTAAAGATCTGGCCTGTTTGTACG
GGCTGGCCAGTTATGTTTTTAATAAAAGTATAGATTTTGAAACTAAAAAAAATTAG

Upstream 100 bases:

>100_bases
AAGTGTTTAATCAAGTATTAAACTAATCAAGTATTAAACTGATATAGAAATAAGTTTATAAGTCCATAACAGATATGGTA
TAAGGAAGGGTTGATTTTAT

Downstream 100 bases:

>100_bases
GGAGGCGACTTAAATGGAAGTATTTAAAAATGTACCACAAACAATAAAATATGAAGGAAAAGATTCTGATAACCCTCTTG
CCTTTAAGTACTACAATCCT

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNVKVGNSTFIKNLNQKRIFKLIHKEGPITRKELADNTDYSAGTISNHVKALIDQGFVIETEKGYSSGGRKPVYLTVNPD
KGYIISVEVEVTRVKIVLFNLKIKVVAKTVFPINGPAQAKETISQIFSEIEKILSEREIKPDKILGIGVAVPGLIDKEEG
LLEFAPNLGWSKVPIVKYFEDKYGVPVVLENEANAAAVGEKEFVYPDIKDMVYVSINEGIGCGLIFNGRLYRGAGGNAGE
FGHIIIDSDGPLCHCGNSGCWETLASENHIQKEYQELTGEENVEKNEIYRKAIEGEDRALSVVKQAAHNIGLGLANIVNS
LSPRLIVLGGGIIEADTLIIDTVQSILKEKCLLLSYDKVDIEFTRLKDLACLYGLASYVFNKSIDFETKKN

Sequences:

>Translated_391_residues
MNVKVGNSTFIKNLNQKRIFKLIHKEGPITRKELADNTDYSAGTISNHVKALIDQGFVIETEKGYSSGGRKPVYLTVNPD
KGYIISVEVEVTRVKIVLFNLKIKVVAKTVFPINGPAQAKETISQIFSEIEKILSEREIKPDKILGIGVAVPGLIDKEEG
LLEFAPNLGWSKVPIVKYFEDKYGVPVVLENEANAAAVGEKEFVYPDIKDMVYVSINEGIGCGLIFNGRLYRGAGGNAGE
FGHIIIDSDGPLCHCGNSGCWETLASENHIQKEYQELTGEENVEKNEIYRKAIEGEDRALSVVKQAAHNIGLGLANIVNS
LSPRLIVLGGGIIEADTLIIDTVQSILKEKCLLLSYDKVDIEFTRLKDLACLYGLASYVFNKSIDFETKKN
>Mature_391_residues
MNVKVGNSTFIKNLNQKRIFKLIHKEGPITRKELADNTDYSAGTISNHVKALIDQGFVIETEKGYSSGGRKPVYLTVNPD
KGYIISVEVEVTRVKIVLFNLKIKVVAKTVFPINGPAQAKETISQIFSEIEKILSEREIKPDKILGIGVAVPGLIDKEEG
LLEFAPNLGWSKVPIVKYFEDKYGVPVVLENEANAAAVGEKEFVYPDIKDMVYVSINEGIGCGLIFNGRLYRGAGGNAGE
FGHIIIDSDGPLCHCGNSGCWETLASENHIQKEYQELTGEENVEKNEIYRKAIEGEDRALSVVKQAAHNIGLGLANIVNS
LSPRLIVLGGGIIEADTLIIDTVQSILKEKCLLLSYDKVDIEFTRLKDLACLYGLASYVFNKSIDFETKKN

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=285, Percent_Identity=27.3684210526316, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI298566325, Length=285, Percent_Identity=27.3684210526316, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4885285, Length=285, Percent_Identity=27.3684210526316, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI298566315, Length=304, Percent_Identity=26.9736842105263, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI298566312, Length=136, Percent_Identity=30.1470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786891, Length=361, Percent_Identity=27.1468144044321, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787878, Length=390, Percent_Identity=23.3333333333333, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082127, Length=336, Percent_Identity=25.8928571428571, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI87082230, Length=220, Percent_Identity=30, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87081733, Length=279, Percent_Identity=29.0322580645161, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787363, Length=200, Percent_Identity=30, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790522, Length=214, Percent_Identity=24.2990654205607, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 43053; Mature: 43053

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKVGNSTFIKNLNQKRIFKLIHKEGPITRKELADNTDYSAGTISNHVKALIDQGFVIE
CCEECCCHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
TEKGYSSGGRKPVYLTVNPDKGYIISVEVEVTRVKIVLFNLKIKVVAKTVFPINGPAQAK
ECCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEEEEEEEEEEEEEEECCCCCHHHH
ETISQIFSEIEKILSEREIKPDKILGIGVAVPGLIDKEEGLLEFAPNLGWSKVPIVKYFE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHEECCCCCCCCCCEEEEEC
DKYGVPVVLENEANAAAVGEKEFVYPDIKDMVYVSINEGIGCGLIFNGRLYRGAGGNAGE
CCCCCCEEEECCCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCEEEECCCCCCCC
FGHIIIDSDGPLCHCGNSGCWETLASENHIQKEYQELTGEENVEKNEIYRKAIEGEDRAL
EEEEEECCCCCEEECCCCCHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHH
SVVKQAAHNIGLGLANIVNSLSPRLIVLGGGIIEADTLIIDTVQSILKEKCLLLSYDKVD
HHHHHHHHHCCCCHHHHHHCCCCEEEEEECCEEECHHHHHHHHHHHHHCCCEEEEECCCC
IEFTRLKDLACLYGLASYVFNKSIDFETKKN
EEHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNVKVGNSTFIKNLNQKRIFKLIHKEGPITRKELADNTDYSAGTISNHVKALIDQGFVIE
CCEECCCHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
TEKGYSSGGRKPVYLTVNPDKGYIISVEVEVTRVKIVLFNLKIKVVAKTVFPINGPAQAK
ECCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEEEEEEEEEEEEEEECCCCCHHHH
ETISQIFSEIEKILSEREIKPDKILGIGVAVPGLIDKEEGLLEFAPNLGWSKVPIVKYFE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHEECCCCCCCCCCEEEEEC
DKYGVPVVLENEANAAAVGEKEFVYPDIKDMVYVSINEGIGCGLIFNGRLYRGAGGNAGE
CCCCCCEEEECCCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCEEEECCCCCCCC
FGHIIIDSDGPLCHCGNSGCWETLASENHIQKEYQELTGEENVEKNEIYRKAIEGEDRAL
EEEEEECCCCCEEECCCCCHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHH
SVVKQAAHNIGLGLANIVNSLSPRLIVLGGGIIEADTLIIDTVQSILKEKCLLLSYDKVD
HHHHHHHHHCCCCHHHHHHCCCCEEEEEECCEEECHHHHHHHHHHHHHCCCEEEEECCCC
IEFTRLKDLACLYGLASYVFNKSIDFETKKN
EEHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]