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The map label for this gene is lpxP [H]

Identifier: 220932725

GI number: 220932725

Start: 2020309

End: 2021178

Strand: Reverse

Name: lpxP [H]

Synonym: Hore_18900

Alternate gene names: 220932725

Gene position: 2021178-2020309 (Counterclockwise)

Preceding gene: 220932726

Following gene: 220932724

Centisome position: 78.4

GC content: 43.91

Gene sequence:

>870_bases
ATGGTGAAGAATATTATACTCTATTTGGTCTTTGAAGGTTTTTTACTATTTATCAGAATATTACCCGGTTTTTTACGCCA
GATGGTGGGTCTTTTTTTCGGTAAGGTTCTTTATTATCTACCGGGAAACCGTAAAAAAGTGGCTTATAATAATTTGAAAA
TGGCTTTCGATGATTTATCAGATGACAGGATAAAGGAAATCATCAGGAAGGTTTATATAAACCTGGGGTTTATGCTGGTC
GAATATGCTCTGACCCCGGGACTTAATAAGGATAATATGACTAAACATATTGAGCTGGAAGGGGAAGAGCACCTGAAAAA
GGCCTTTGACCGGGGAAAAGGTGTTATTGTCTACGGTGCCCATTTTGGTAACTGGGAATGGATGGGGATTGCCATCTCCC
TTATGGGGTATCCCATGGCTGCCATTGTCCAGGAACAGAATAACTCCTATTTTGACAGAAGGATTAACCAGATGAGACAG
CAAAAGGGAGTTGAGACCATACAGAGAGGGATGTCGGTCCGGAAGGCCTTTAAGGCCCTGAAAGAGGGTAAATGTCTTCT
TATCCTCGGTGACCAGGATGCCAGGAGCCGGGGCTGGAGATTAAAATTTTTCGGGAAAACGGCCTCTACATTTCCCGGGG
CTGTACAGCTGGCCAGAAGGACAGGGGCCCTGATTGTTCCTGCCTTTATGGTCCGGAAATCCCGGGGGAAGCACAGATTG
AAGTTTTACCGGCCCATTGAAATAGGGGCTGAGGCTTCCATGGAAGAACAGAAAGAGTTTTTACAGGAGTTAAATCATAT
TACAGAATCGGTTATAAAAAAATATCCCGACCACTGGCTATGGCTACACCGTCGCTGGAAAACTTATTAA

Upstream 100 bases:

>100_bases
TAATGACCTGCCGGTAGTCGAAGATGGGAAGCCAGTGGGAATGCTTAACTTCCAGGACCTGTTAAGGGCCCGGGTCTTTT
AGGGAAAAGATGGGGTGGAT

Downstream 100 bases:

>100_bases
GCTTTAGAAGGTGTTTATCATTTGAAGGTTTATCAAATGAGTAAAGGGGGGCTGGATCCAGATGTTTATATTTTACTTAA
TCTATAATCTGCTCTTAATA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MVKNIILYLVFEGFLLFIRILPGFLRQMVGLFFGKVLYYLPGNRKKVAYNNLKMAFDDLSDDRIKEIIRKVYINLGFMLV
EYALTPGLNKDNMTKHIELEGEEHLKKAFDRGKGVIVYGAHFGNWEWMGIAISLMGYPMAAIVQEQNNSYFDRRINQMRQ
QKGVETIQRGMSVRKAFKALKEGKCLLILGDQDARSRGWRLKFFGKTASTFPGAVQLARRTGALIVPAFMVRKSRGKHRL
KFYRPIEIGAEASMEEQKEFLQELNHITESVIKKYPDHWLWLHRRWKTY

Sequences:

>Translated_289_residues
MVKNIILYLVFEGFLLFIRILPGFLRQMVGLFFGKVLYYLPGNRKKVAYNNLKMAFDDLSDDRIKEIIRKVYINLGFMLV
EYALTPGLNKDNMTKHIELEGEEHLKKAFDRGKGVIVYGAHFGNWEWMGIAISLMGYPMAAIVQEQNNSYFDRRINQMRQ
QKGVETIQRGMSVRKAFKALKEGKCLLILGDQDARSRGWRLKFFGKTASTFPGAVQLARRTGALIVPAFMVRKSRGKHRL
KFYRPIEIGAEASMEEQKEFLQELNHITESVIKKYPDHWLWLHRRWKTY
>Mature_289_residues
MVKNIILYLVFEGFLLFIRILPGFLRQMVGLFFGKVLYYLPGNRKKVAYNNLKMAFDDLSDDRIKEIIRKVYINLGFMLV
EYALTPGLNKDNMTKHIELEGEEHLKKAFDRGKGVIVYGAHFGNWEWMGIAISLMGYPMAAIVQEQNNSYFDRRINQMRQ
QKGVETIQRGMSVRKAFKALKEGKCLLILGDQDARSRGWRLKFFGKTASTFPGAVQLARRTGALIVPAFMVRKSRGKHRL
KFYRPIEIGAEASMEEQKEFLQELNHITESVIKKYPDHWLWLHRRWKTY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=247, Percent_Identity=28.7449392712551, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787292, Length=278, Percent_Identity=25.1798561151079, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 33778; Mature: 33778

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS00636 DNAJ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNIILYLVFEGFLLFIRILPGFLRQMVGLFFGKVLYYLPGNRKKVAYNNLKMAFDDLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCC
DDRIKEIIRKVYINLGFMLVEYALTPGLNKDNMTKHIELEGEEHLKKAFDRGKGVIVYGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEECC
HFGNWEWMGIAISLMGYPMAAIVQEQNNSYFDRRINQMRQQKGVETIQRGMSVRKAFKAL
CCCCEEHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEGKCLLILGDQDARSRGWRLKFFGKTASTFPGAVQLARRTGALIVPAFMVRKSRGKHRL
HCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCE
KFYRPIEIGAEASMEEQKEFLQELNHITESVIKKYPDHWLWLHRRWKTY
EEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MVKNIILYLVFEGFLLFIRILPGFLRQMVGLFFGKVLYYLPGNRKKVAYNNLKMAFDDLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCC
DDRIKEIIRKVYINLGFMLVEYALTPGLNKDNMTKHIELEGEEHLKKAFDRGKGVIVYGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEECC
HFGNWEWMGIAISLMGYPMAAIVQEQNNSYFDRRINQMRQQKGVETIQRGMSVRKAFKAL
CCCCEEHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEGKCLLILGDQDARSRGWRLKFFGKTASTFPGAVQLARRTGALIVPAFMVRKSRGKHRL
HCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCE
KFYRPIEIGAEASMEEQKEFLQELNHITESVIKKYPDHWLWLHRRWKTY
EEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]