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The map label for this gene is yisQ [H]

Identifier: 220932685

GI number: 220932685

Start: 1973825

End: 1975153

Strand: Reverse

Name: yisQ [H]

Synonym: Hore_18490

Alternate gene names: 220932685

Gene position: 1975153-1973825 (Counterclockwise)

Preceding gene: 220932686

Following gene: 220932684

Centisome position: 76.61

GC content: 38.0

Gene sequence:

>1329_bases
ATGGAAAAAAGAAAAAGCCTGTTTCAATTAGCTGTACCTATATTTATTGAGACCCTCCTGTTTATGTTGTTGGGTATAGC
TGATATTTTTATGCTAAGTCAATTTGATGACAGGGCTGCTGGGGCTGTTGGGGCTTCTAACCAGGTAATAGGAAATTTAA
ATTTAATTTTTGCCATAATTTCAGCAGGTACAGCAGTTTTAGTGGCCCAGAATGTGGGAGCAAAAAATAAAAGGGAAATA
GAGAGGGTATGTTCTATCTCCCTGGTTATGAATTTTGTCATTGGTCTTTTAGTTAGTATTACCATGATATTCTTTGGTGA
TGTGATACTGACTAAAATGGGTGTTACCCGGAGTCTAATGGGGTATGCATCTAATTATATAAAGATTGTCGGTGGGGCCT
TATTTGTTCAGTCAATATTAAATACTGTTACTGTAATCATCAGGAGCCATGGCTATACCAGGGAAAGTATGTTAATAACA
GTCGGGATGAATATTTTAAATATCTTTGGTGATGCTGTTTTTATCTTTGGCCTGTTTGGGGCTCCGGTACTGGGTGTTAA
AGGGGTCGCTATTGCTACTACTGTAAGTAGAATACTGGCTACGATTATAGCATTTATATTTTTGTTCAAGGGGCTGGTAC
CAGTTAGTATGTTTAAATATTTATATGATAAACCTGTAGGTACTTTTAAAAAACTAATAAAAATTGGCTTCCCATCTGCT
ATGGAGAATATGTCTTATTCCCTAGCCCAAACAGTAATAATGAGTATTATATTATTAAATTTAGGGGAACAGGCCTATAT
TGCCAGGACTTATATCTGGACATTGAGCTGGTTTGTGGTCTTGTTTTCAATTTCTATCGGGCAGGCCAACCAGATTATGA
TTGGCCAGTTAACCGGGGCTGGTAAAGTGGAAGAGGCCTATCATACCGGGCTTAATAACTTTAAAACAGCTATGTTATTT
TCAGTTCTTGGGGGAATAGCTTTAATAATTTTTAGAAGAAAGTTAATAGGTATTTATACTGATAACCAGGATATTATTTT
GATAGGGTCAATTACCCTGATAGTGGATGCTTTCCTTGAACCCGGTAGAACCTTTAATATTGTCCTTATTAATGGTTTAA
GGGGGGCAGGAGATGTTATTTTTCCCGTTGTTATGGCCATTATAAGTATGTGGGGTCTTGGCGTTACAACTGCATACTAT
TTTGGTGTTGTTCTGGGACTGGGTCTTCCCGGTATCTGGATGGGTTTAATACTTGATGAGTGGTTCCGCGGGGTCTGCAT
GTTATTCAGGTGGCGAGGGAAAAAATGGGTAAGAAAAGTGATGGTGTAG

Upstream 100 bases:

>100_bases
TGTGAAAGATTGTCAAAAAGTCCGTTAATGCTTGTTATAATGGACAGTAATACTTACATATGACACTATAAAAAACAGTA
AATGTAAGAGGTGTAACAGC

Downstream 100 bases:

>100_bases
AAGGCAAATCTTCAGATAAAGGGGTTAGTGAGGGATAAAACAGGAGGTATTTATACTGAAAGTCTGGAAATTAGAGAGTA
TAATCTTCAATTTAAAGTAA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MEKRKSLFQLAVPIFIETLLFMLLGIADIFMLSQFDDRAAGAVGASNQVIGNLNLIFAIISAGTAVLVAQNVGAKNKREI
ERVCSISLVMNFVIGLLVSITMIFFGDVILTKMGVTRSLMGYASNYIKIVGGALFVQSILNTVTVIIRSHGYTRESMLIT
VGMNILNIFGDAVFIFGLFGAPVLGVKGVAIATTVSRILATIIAFIFLFKGLVPVSMFKYLYDKPVGTFKKLIKIGFPSA
MENMSYSLAQTVIMSIILLNLGEQAYIARTYIWTLSWFVVLFSISIGQANQIMIGQLTGAGKVEEAYHTGLNNFKTAMLF
SVLGGIALIIFRRKLIGIYTDNQDIILIGSITLIVDAFLEPGRTFNIVLINGLRGAGDVIFPVVMAIISMWGLGVTTAYY
FGVVLGLGLPGIWMGLILDEWFRGVCMLFRWRGKKWVRKVMV

Sequences:

>Translated_442_residues
MEKRKSLFQLAVPIFIETLLFMLLGIADIFMLSQFDDRAAGAVGASNQVIGNLNLIFAIISAGTAVLVAQNVGAKNKREI
ERVCSISLVMNFVIGLLVSITMIFFGDVILTKMGVTRSLMGYASNYIKIVGGALFVQSILNTVTVIIRSHGYTRESMLIT
VGMNILNIFGDAVFIFGLFGAPVLGVKGVAIATTVSRILATIIAFIFLFKGLVPVSMFKYLYDKPVGTFKKLIKIGFPSA
MENMSYSLAQTVIMSIILLNLGEQAYIARTYIWTLSWFVVLFSISIGQANQIMIGQLTGAGKVEEAYHTGLNNFKTAMLF
SVLGGIALIIFRRKLIGIYTDNQDIILIGSITLIVDAFLEPGRTFNIVLINGLRGAGDVIFPVVMAIISMWGLGVTTAYY
FGVVLGLGLPGIWMGLILDEWFRGVCMLFRWRGKKWVRKVMV
>Mature_442_residues
MEKRKSLFQLAVPIFIETLLFMLLGIADIFMLSQFDDRAAGAVGASNQVIGNLNLIFAIISAGTAVLVAQNVGAKNKREI
ERVCSISLVMNFVIGLLVSITMIFFGDVILTKMGVTRSLMGYASNYIKIVGGALFVQSILNTVTVIIRSHGYTRESMLIT
VGMNILNIFGDAVFIFGLFGAPVLGVKGVAIATTVSRILATIIAFIFLFKGLVPVSMFKYLYDKPVGTFKKLIKIGFPSA
MENMSYSLAQTVIMSIILLNLGEQAYIARTYIWTLSWFVVLFSISIGQANQIMIGQLTGAGKVEEAYHTGLNNFKTAMLF
SVLGGIALIIFRRKLIGIYTDNQDIILIGSITLIVDAFLEPGRTFNIVLINGLRGAGDVIFPVVMAIISMWGLGVTTAYY
FGVVLGLGLPGIWMGLILDEWFRGVCMLFRWRGKKWVRKVMV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=446, Percent_Identity=25.3363228699552, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI48994890, Length=447, Percent_Identity=20.3579418344519, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48481; Mature: 48481

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRKSLFQLAVPIFIETLLFMLLGIADIFMLSQFDDRAAGAVGASNQVIGNLNLIFAII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHH
SAGTAVLVAQNVGAKNKREIERVCSISLVMNFVIGLLVSITMIFFGDVILTKMGVTRSLM
HCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYASNYIKIVGGALFVQSILNTVTVIIRSHGYTRESMLITVGMNILNIFGDAVFIFGLFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHC
APVLGVKGVAIATTVSRILATIIAFIFLFKGLVPVSMFKYLYDKPVGTFKKLIKIGFPSA
CCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHH
MENMSYSLAQTVIMSIILLNLGEQAYIARTYIWTLSWFVVLFSISIGQANQIMIGQLTGA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
GKVEEAYHTGLNNFKTAMLFSVLGGIALIIFRRKLIGIYTDNQDIILIGSITLIVDAFLE
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHC
PGRTFNIVLINGLRGAGDVIFPVVMAIISMWGLGVTTAYYFGVVLGLGLPGIWMGLILDE
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
WFRGVCMLFRWRGKKWVRKVMV
HHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MEKRKSLFQLAVPIFIETLLFMLLGIADIFMLSQFDDRAAGAVGASNQVIGNLNLIFAII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHH
SAGTAVLVAQNVGAKNKREIERVCSISLVMNFVIGLLVSITMIFFGDVILTKMGVTRSLM
HCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYASNYIKIVGGALFVQSILNTVTVIIRSHGYTRESMLITVGMNILNIFGDAVFIFGLFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHC
APVLGVKGVAIATTVSRILATIIAFIFLFKGLVPVSMFKYLYDKPVGTFKKLIKIGFPSA
CCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHH
MENMSYSLAQTVIMSIILLNLGEQAYIARTYIWTLSWFVVLFSISIGQANQIMIGQLTGA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
GKVEEAYHTGLNNFKTAMLFSVLGGIALIIFRRKLIGIYTDNQDIILIGSITLIVDAFLE
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHC
PGRTFNIVLINGLRGAGDVIFPVVMAIISMWGLGVTTAYYFGVVLGLGLPGIWMGLILDE
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
WFRGVCMLFRWRGKKWVRKVMV
HHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]