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The map label for this gene is apeA [H]

Identifier: 220932650

GI number: 220932650

Start: 1935537

End: 1936931

Strand: Reverse

Name: apeA [H]

Synonym: Hore_18140

Alternate gene names: 220932650

Gene position: 1936931-1935537 (Counterclockwise)

Preceding gene: 220932651

Following gene: 220932649

Centisome position: 75.13

GC content: 44.95

Gene sequence:

>1395_bases
ATGGGAAAGAAATTTGAAATTAAGAATGCCTGGCTGGAAATGGCCGGGGCCGAGAAAGAAGAAATAAATCAATTTAATAA
AGATTATGCAGGATTCATTACAGTTAATAAGACAGAGCGGGAGTTTGTTAAGGCTGCTGTAGAACTACTGGAAAAGGAAG
GATTTAAAAATTTAGAAGAGGTTCAAAAACTAAGAGAAGGTGACCGGGTATATAAGGTTAACCGGGACCGGGCCATTGCT
GCTGCTGTAATCGGTCAGAGACCCTTGACCGATGGGTTGCGGATTGTTGGGGCCCACCTCGATTCACCCCGGATTGATTT
AAAGCCCAATCCAGTGTATGAGGATAGTGAGCTAGTTTTCTTCAACACTCATTATTACGGGGGGATAAAAAAATATCAGT
GGGTTTCAATTCCCCTGGCCCTTCATGGGGTTGTAGTCAAAGAGGATGGTACCAGAGTTGATGTTGTTATCGGTGAAAAT
GAATCTGACCCAATTTTTTACATAAGTGATTTATTACCTCATTTAAGTAAAGACCAGATGAAGAAGAAGATGACAGAAGG
TATAACCGGGGAACAGCTGGATGTCCTCATCGGGAGTGTACCTGCCGGGGAAGAAGAAGATAGTGACAAGGTCAAGGTAA
AATCAGCTGTGCTTGATTTATTAAATGAGAAATATGGAATTACCGAGGAGGATCTGGTTAGTGCTGACCTGAAGTTGGTA
CCCGCTTATAGAGCGAGAGACCTCGGCTTTGACCGGGGGCTTCTGGCCGGATACGGACATGATGATCGGGTCTGTAGCTA
TACAGCTTTGCGCGGATTAATAGATCTGGAAACACCAGAATATACCGGGGTTGCTCTTCTGGTTGATAAAGAAGAAATTG
GAAGTATGGGGGCTACCGGAATGCAGTCCAGGTTTTTCGAGAACTGCCTGGCAGAGATGATTGATCTAACCGGTGAAGAT
TATAGTGATCTGGCTTTGAGAAAGGCCCTGGAAAATTCATGGGCCCTGTCGGCTGATGTCAATGCGGCCTTTGACCCCAA
CTTCTCTGATGTTTTTGATAAGGACAACTCTTCCTATCTGGGTAAGGGTGTCGTCTTAACCAAATATACCGGGGCCCGGG
GTAAGTATAGTTCTTCTGAAGCCACTGCTGAATTTGTCGGCAGGGTTAGAGCTCTATTCAATAATGGTGGTGTACCCTGG
CAGATTGGTGAACTCGGCAAGGTTGACCAGGGGGGCGGGGGTACTATCGCCCAGTTCCTGGCCAATTATAATATGGATGT
TGTTGACTGTGGCCCTGCGGTTTTATCTATGCACTCTCCTTTTGAAGTTGTAAGCAAGGTTGATGTTTACAGTTCTTATT
TAGCATACAGTGTTTTCTTTGGTAGTCAGGGTTAA

Upstream 100 bases:

>100_bases
CAATAATAATCTGGATAATGAAAAGCCGGCCTGAGGCCGGTTTTTTTATTGATAATTTTTTAATATCTGGATATAATGGT
TAAGGAAAGGAGGAATAGTA

Downstream 100 bases:

>100_bases
ATAATTACCGGTCAGGGGGTTACCTGGCCGGTTTTTTATTTAAATTTAAGGGTTTGTAAATTATTTAACATTAAAATTAT
TGATATGGTTTATAATATGA

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MGKKFEIKNAWLEMAGAEKEEINQFNKDYAGFITVNKTEREFVKAAVELLEKEGFKNLEEVQKLREGDRVYKVNRDRAIA
AAVIGQRPLTDGLRIVGAHLDSPRIDLKPNPVYEDSELVFFNTHYYGGIKKYQWVSIPLALHGVVVKEDGTRVDVVIGEN
ESDPIFYISDLLPHLSKDQMKKKMTEGITGEQLDVLIGSVPAGEEEDSDKVKVKSAVLDLLNEKYGITEEDLVSADLKLV
PAYRARDLGFDRGLLAGYGHDDRVCSYTALRGLIDLETPEYTGVALLVDKEEIGSMGATGMQSRFFENCLAEMIDLTGED
YSDLALRKALENSWALSADVNAAFDPNFSDVFDKDNSSYLGKGVVLTKYTGARGKYSSSEATAEFVGRVRALFNNGGVPW
QIGELGKVDQGGGGTIAQFLANYNMDVVDCGPAVLSMHSPFEVVSKVDVYSSYLAYSVFFGSQG

Sequences:

>Translated_464_residues
MGKKFEIKNAWLEMAGAEKEEINQFNKDYAGFITVNKTEREFVKAAVELLEKEGFKNLEEVQKLREGDRVYKVNRDRAIA
AAVIGQRPLTDGLRIVGAHLDSPRIDLKPNPVYEDSELVFFNTHYYGGIKKYQWVSIPLALHGVVVKEDGTRVDVVIGEN
ESDPIFYISDLLPHLSKDQMKKKMTEGITGEQLDVLIGSVPAGEEEDSDKVKVKSAVLDLLNEKYGITEEDLVSADLKLV
PAYRARDLGFDRGLLAGYGHDDRVCSYTALRGLIDLETPEYTGVALLVDKEEIGSMGATGMQSRFFENCLAEMIDLTGED
YSDLALRKALENSWALSADVNAAFDPNFSDVFDKDNSSYLGKGVVLTKYTGARGKYSSSEATAEFVGRVRALFNNGGVPW
QIGELGKVDQGGGGTIAQFLANYNMDVVDCGPAVLSMHSPFEVVSKVDVYSSYLAYSVFFGSQG
>Mature_463_residues
GKKFEIKNAWLEMAGAEKEEINQFNKDYAGFITVNKTEREFVKAAVELLEKEGFKNLEEVQKLREGDRVYKVNRDRAIAA
AVIGQRPLTDGLRIVGAHLDSPRIDLKPNPVYEDSELVFFNTHYYGGIKKYQWVSIPLALHGVVVKEDGTRVDVVIGENE
SDPIFYISDLLPHLSKDQMKKKMTEGITGEQLDVLIGSVPAGEEEDSDKVKVKSAVLDLLNEKYGITEEDLVSADLKLVP
AYRARDLGFDRGLLAGYGHDDRVCSYTALRGLIDLETPEYTGVALLVDKEEIGSMGATGMQSRFFENCLAEMIDLTGEDY
SDLALRKALENSWALSADVNAAFDPNFSDVFDKDNSSYLGKGVVLTKYTGARGKYSSSEATAEFVGRVRALFNNGGVPWQ
IGELGKVDQGGGGTIAQFLANYNMDVVDCGPAVLSMHSPFEVVSKVDVYSSYLAYSVFFGSQG

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=466, Percent_Identity=24.8927038626609, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552916, Length=473, Percent_Identity=25.5813953488372, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322746, Length=456, Percent_Identity=24.780701754386, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321905, Length=481, Percent_Identity=25.5717255717256, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51157; Mature: 51026

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKFEIKNAWLEMAGAEKEEINQFNKDYAGFITVNKTEREFVKAAVELLEKEGFKNLEE
CCCEEEHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHH
VQKLREGDRVYKVNRDRAIAAAVIGQRPLTDGLRIVGAHLDSPRIDLKPNPVYEDSELVF
HHHHHCCCCEEEECCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
FNTHYYGGIKKYQWVSIPLALHGVVVKEDGTRVDVVIGENESDPIFYISDLLPHLSKDQM
EEEEEECCCCEEEEEEECEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHCCCCHHHH
KKKMTEGITGEQLDVLIGSVPAGEEEDSDKVKVKSAVLDLLNEKYGITEEDLVSADLKLV
HHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEE
PAYRARDLGFDRGLLAGYGHDDRVCSYTALRGLIDLETPEYTGVALLVDKEEIGSMGATG
CCHHHHHCCCCCCCEECCCCCCCHHHHHHHHCEEECCCCCCCCEEEEEEHHHHCCCCCCH
MQSRFFENCLAEMIDLTGEDYSDLALRKALENSWALSADVNAAFDPNFSDVFDKDNSSYL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHCCCCCCCC
GKGVVLTKYTGARGKYSSSEATAEFVGRVRALFNNGGVPWQIGELGKVDQGGGGTIAQFL
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHH
ANYNMDVVDCGPAVLSMHSPFEVVSKVDVYSSYLAYSVFFGSQG
HHCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCC
>Mature Secondary Structure 
GKKFEIKNAWLEMAGAEKEEINQFNKDYAGFITVNKTEREFVKAAVELLEKEGFKNLEE
CCEEEHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHH
VQKLREGDRVYKVNRDRAIAAAVIGQRPLTDGLRIVGAHLDSPRIDLKPNPVYEDSELVF
HHHHHCCCCEEEECCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
FNTHYYGGIKKYQWVSIPLALHGVVVKEDGTRVDVVIGENESDPIFYISDLLPHLSKDQM
EEEEEECCCCEEEEEEECEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHCCCCHHHH
KKKMTEGITGEQLDVLIGSVPAGEEEDSDKVKVKSAVLDLLNEKYGITEEDLVSADLKLV
HHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEE
PAYRARDLGFDRGLLAGYGHDDRVCSYTALRGLIDLETPEYTGVALLVDKEEIGSMGATG
CCHHHHHCCCCCCCEECCCCCCCHHHHHHHHCEEECCCCCCCCEEEEEEHHHHCCCCCCH
MQSRFFENCLAEMIDLTGEDYSDLALRKALENSWALSADVNAAFDPNFSDVFDKDNSSYL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHCCCCCCCC
GKGVVLTKYTGARGKYSSSEATAEFVGRVRALFNNGGVPWQIGELGKVDQGGGGTIAQFL
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHH
ANYNMDVVDCGPAVLSMHSPFEVVSKVDVYSSYLAYSVFFGSQG
HHCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]