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The map label for this gene is gpmI

Identifier: 220932416

GI number: 220932416

Start: 1691712

End: 1693250

Strand: Reverse

Name: gpmI

Synonym: Hore_15800

Alternate gene names: 220932416

Gene position: 1693250-1691712 (Counterclockwise)

Preceding gene: 220932417

Following gene: 220932415

Centisome position: 65.68

GC content: 44.18

Gene sequence:

>1539_bases
ATGAATCGTCCTAAACCGTTAGCCCTGATTATAATGGATGGTTTTGGATTAAGTGAAAAATCTGATGGGAATGCTATAAA
ACAGGCCCACACCCCCAATCTTGATAAATTTTTTGAAGAATACCCTGATACGGTGCTGGATGCATCCGGGGAAGCAGTTG
GGCTTCCGGAAGGGCAAATGGGGAATTCAGAGGTTGGCCACCTGAATCTGGGGGCTGGCCGGATTGTATACCAGGATTAT
ACCCGGATTAATAAAGCTATTGAAGAGGGAACCCTGCCTGAAAATGATGCCTTAAAGAACGCTATCCAGCATGTTAAAGA
TAATAATTCTGCCCTTCATTTAATGGGACTGCTTTCTGATGGGGGTGTCCACAGCCATATCAATCATCTCTTTGGTCTTC
TGGAGATGGCCAGAGTTAAGAATATAGAAAAAGTATATGTTCACCCCATTCTTGATGGACGGGATACACCGCCCCGGAGT
GCTGAAAAATATTTGAACCAGCTGGAAGAAAAGCTGGCAGAGCTGGGCATCGGTGAAATCGCAACCGTAAGTGGACGTTA
TTACACTATGGACCGGGATAATCGCTGGGACAGGACCAAAAAAAGTTATGATGCCCTGGTTTTAGGTGAAGGGCTTGAAG
CCAGTGATGCTATCAGTGCCCTGAAACAGTCCTATGCAGCCGATAAGAGTGACGAGTTTGTTATTCCCACTGTTATCAAG
AAAAACGGCCAACCGGTTGGTACCATTAAAGATAATGATGCTGTTATCTTTTATAATTTCAGGGCTGACAGGGCCCGTCA
GATAACAAAGGCCCTTGCCCTTGAGGAATTTGATGAGTTTGAAAGGCCAGCGGAACATCCCGAAAATCTTTATTATGTCT
GTATGGCAGAATATGATGAGGAATTTAACCTGCCGGTTGCTTTTCCACCACTTGAAATAAAAAATGGATTTGGTGAAATT
TTAAGTAAAGAGGGCTTTAAACAGCTCAGGATAGCCGAAACTGAAAAATATGCCCATGTTACCTTCTTCTTTAATGGTGG
GGTAGAGAAGAAATATCCGGGTGAAGACCGGGTCCTTGTTCCCTCACCAAAGGTTGCTACCTATGATGAAAAACCGGAAA
TGAGTGCCTATGAAGTAACCGATAAACTCCTGGAGAAACTCGATGAAGATAAATATGATGTTATTATCCTTAATTTTGCT
AACCCTGATATGGTTGGTCACACCGGCTTTATGGATGCAGCCGTTAAAGCAGTTGAAGCTGTTGATGAATGCCTTGGTAA
GATTATTCCCAGAATAGTGGATATGGGGGGACAGGTTTTACTGACTGCTGACCATGGAAATAGTGAAAAGATGAAAGATA
GTGAAGGCAAACCACATACCGCCCACACCACAAACCAGGTACCCCTCATTTATATTGGTGGACCTGAAGGTGTCGGGGTT
AAACCCGGAAAGCTGGCTGATATTGCACCAACCATGCTAGAAATACTGGGCCTGGATACGCCTGAAGAAATGACAGGGCA
GTCACTTCTGACCCGATAA

Upstream 100 bases:

>100_bases
GCAATGTTTTTTAATAAAGCATTAAATATATCAACAGATATTGTATATTTAAATGTAATATGTTACTGAATGGCAAAGTT
TAAGGAAAGAGGTGAGGATG

Downstream 100 bases:

>100_bases
ACCTGTTAATAACATGTTTGTTAATGGTTTTGTCTATATTTCTGCCAGTAATGTGATTGGAAGACATAATTAGAATCAAA
TAAAAACTTATAAACAATAT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MNRPKPLALIIMDGFGLSEKSDGNAIKQAHTPNLDKFFEEYPDTVLDASGEAVGLPEGQMGNSEVGHLNLGAGRIVYQDY
TRINKAIEEGTLPENDALKNAIQHVKDNNSALHLMGLLSDGGVHSHINHLFGLLEMARVKNIEKVYVHPILDGRDTPPRS
AEKYLNQLEEKLAELGIGEIATVSGRYYTMDRDNRWDRTKKSYDALVLGEGLEASDAISALKQSYAADKSDEFVIPTVIK
KNGQPVGTIKDNDAVIFYNFRADRARQITKALALEEFDEFERPAEHPENLYYVCMAEYDEEFNLPVAFPPLEIKNGFGEI
LSKEGFKQLRIAETEKYAHVTFFFNGGVEKKYPGEDRVLVPSPKVATYDEKPEMSAYEVTDKLLEKLDEDKYDVIILNFA
NPDMVGHTGFMDAAVKAVEAVDECLGKIIPRIVDMGGQVLLTADHGNSEKMKDSEGKPHTAHTTNQVPLIYIGGPEGVGV
KPGKLADIAPTMLEILGLDTPEEMTGQSLLTR

Sequences:

>Translated_512_residues
MNRPKPLALIIMDGFGLSEKSDGNAIKQAHTPNLDKFFEEYPDTVLDASGEAVGLPEGQMGNSEVGHLNLGAGRIVYQDY
TRINKAIEEGTLPENDALKNAIQHVKDNNSALHLMGLLSDGGVHSHINHLFGLLEMARVKNIEKVYVHPILDGRDTPPRS
AEKYLNQLEEKLAELGIGEIATVSGRYYTMDRDNRWDRTKKSYDALVLGEGLEASDAISALKQSYAADKSDEFVIPTVIK
KNGQPVGTIKDNDAVIFYNFRADRARQITKALALEEFDEFERPAEHPENLYYVCMAEYDEEFNLPVAFPPLEIKNGFGEI
LSKEGFKQLRIAETEKYAHVTFFFNGGVEKKYPGEDRVLVPSPKVATYDEKPEMSAYEVTDKLLEKLDEDKYDVIILNFA
NPDMVGHTGFMDAAVKAVEAVDECLGKIIPRIVDMGGQVLLTADHGNSEKMKDSEGKPHTAHTTNQVPLIYIGGPEGVGV
KPGKLADIAPTMLEILGLDTPEEMTGQSLLTR
>Mature_512_residues
MNRPKPLALIIMDGFGLSEKSDGNAIKQAHTPNLDKFFEEYPDTVLDASGEAVGLPEGQMGNSEVGHLNLGAGRIVYQDY
TRINKAIEEGTLPENDALKNAIQHVKDNNSALHLMGLLSDGGVHSHINHLFGLLEMARVKNIEKVYVHPILDGRDTPPRS
AEKYLNQLEEKLAELGIGEIATVSGRYYTMDRDNRWDRTKKSYDALVLGEGLEASDAISALKQSYAADKSDEFVIPTVIK
KNGQPVGTIKDNDAVIFYNFRADRARQITKALALEEFDEFERPAEHPENLYYVCMAEYDEEFNLPVAFPPLEIKNGFGEI
LSKEGFKQLRIAETEKYAHVTFFFNGGVEKKYPGEDRVLVPSPKVATYDEKPEMSAYEVTDKLLEKLDEDKYDVIILNFA
NPDMVGHTGFMDAAVKAVEAVDECLGKIIPRIVDMGGQVLLTADHGNSEKMKDSEGKPHTAHTTNQVPLIYIGGPEGVGV
KPGKLADIAPTMLEILGLDTPEEMTGQSLLTR

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=508, Percent_Identity=53.3464566929134, Blast_Score=563, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17507741, Length=514, Percent_Identity=46.8871595330739, Blast_Score=466, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI32564249, Length=513, Percent_Identity=46.3937621832359, Blast_Score=466, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_HALOH (B8CYG0)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002509324.1
- ProteinModelPortal:   B8CYG0
- GeneID:   7312616
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_15800
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- ProtClustDB:   PRK05434
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 56670; Mature: 56670

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPKPLALIIMDGFGLSEKSDGNAIKQAHTPNLDKFFEEYPDTVLDASGEAVGLPEGQM
CCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHCCHHHCCCCCCEECCCCCCC
GNSEVGHLNLGAGRIVYQDYTRINKAIEEGTLPENDALKNAIQHVKDNNSALHLMGLLSD
CCCCCCEEECCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEECC
GGVHSHINHLFGLLEMARVKNIEKVYVHPILDGRDTPPRSAEKYLNQLEEKLAELGIGEI
CCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCE
ATVSGRYYTMDRDNRWDRTKKSYDALVLGEGLEASDAISALKQSYAADKSDEFVIPTVIK
EEECCEEEECCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEHHHH
KNGQPVGTIKDNDAVIFYNFRADRARQITKALALEEFDEFERPAEHPENLYYVCMAEYDE
CCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
EFNLPVAFPPLEIKNGFGEILSKEGFKQLRIAETEKYAHVTFFFNGGVEKKYPGEDRVLV
CCCCCEECCCHHHHCCHHHHHHHCCHHHHEEECCCCEEEEEEEEECCCCCCCCCCCCEEC
PSPKVATYDEKPEMSAYEVTDKLLEKLDEDKYDVIILNFANPDMVGHTGFMDAAVKAVEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
VDECLGKIIPRIVDMGGQVLLTADHGNSEKMKDSEGKPHTAHTTNQVPLIYIGGPEGVGV
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
KPGKLADIAPTMLEILGLDTPEEMTGQSLLTR
CCCCCHHHHHHHHHHHCCCCCHHHCCHHHHCC
>Mature Secondary Structure
MNRPKPLALIIMDGFGLSEKSDGNAIKQAHTPNLDKFFEEYPDTVLDASGEAVGLPEGQM
CCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHCCHHHCCCCCCEECCCCCCC
GNSEVGHLNLGAGRIVYQDYTRINKAIEEGTLPENDALKNAIQHVKDNNSALHLMGLLSD
CCCCCCEEECCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEECC
GGVHSHINHLFGLLEMARVKNIEKVYVHPILDGRDTPPRSAEKYLNQLEEKLAELGIGEI
CCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCE
ATVSGRYYTMDRDNRWDRTKKSYDALVLGEGLEASDAISALKQSYAADKSDEFVIPTVIK
EEECCEEEECCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEHHHH
KNGQPVGTIKDNDAVIFYNFRADRARQITKALALEEFDEFERPAEHPENLYYVCMAEYDE
CCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
EFNLPVAFPPLEIKNGFGEILSKEGFKQLRIAETEKYAHVTFFFNGGVEKKYPGEDRVLV
CCCCCEECCCHHHHCCHHHHHHHCCHHHHEEECCCCEEEEEEEEECCCCCCCCCCCCEEC
PSPKVATYDEKPEMSAYEVTDKLLEKLDEDKYDVIILNFANPDMVGHTGFMDAAVKAVEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
VDECLGKIIPRIVDMGGQVLLTADHGNSEKMKDSEGKPHTAHTTNQVPLIYIGGPEGVGV
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
KPGKLADIAPTMLEILGLDTPEEMTGQSLLTR
CCCCCHHHHHHHHHHHCCCCCHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA