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The map label for this gene is clpX

Identifier: 220932329

GI number: 220932329

Start: 1591630

End: 1592880

Strand: Reverse

Name: clpX

Synonym: Hore_14930

Alternate gene names: 220932329

Gene position: 1592880-1591630 (Counterclockwise)

Preceding gene: 220932330

Following gene: 220932328

Centisome position: 61.78

GC content: 41.65

Gene sequence:

>1251_bases
ATGTTTAAATTTGGAGATGAAAAGGGTCAGTTGAAATGTTCCTTCTGCGGGAAATCCCAGGAACAGGTCCGTAAACTGGT
AGCTGGCCCCGGGGTATATATATGTGATGAGTGTATTGAACTCTGTAATGAAATAATAGAAGAGGAATTAAACGATGATG
TGGAGTTCAATCTTAATAATATACCTAAACCCCGTGAAATAAAGAAAATCCTTGACCAGTATGTAGTCGGTCAGGAACGG
GCCAAAAAATCACTGTCAGTGGCTGTCTATAACCATTACAAGAGAGTAAATTCTGATATGAAAATAGATGATGTTGAGTT
GCAGAAGAGTAATATTTTGATGGTAGGCCCGACCGGATGTGGAAAGACACTGTTAGCCCAGACACTGGCCAGAATACTGG
ATGTACCCTTTGCTATTACCGATGCCACCTCTTTAACCGAAGCAGGATATGTTGGTGAGGATGTAGAAAATATTCTGCTG
AAATTAATTCAGGCTGCTGATTATGATATCGAAAAAGCAGAACGGGGTATTATCTATATCGATGAAATAGACAAAATAGC
CCGGAAATCCGAAAATCCGTCTATTACCAGGGATGTTTCCGGAGAAGGTGTTCAGCAGGCCCTCCTGAAAATTCTGGAAG
GAACAGTTGCCAGTGTACCGCCCCAGGGAGGGAGAAAACATCCACACCAGGAGTTTATCCAGATAGATACTACCAATATT
CTGTTTATAGCCGGTGGTGCTTTTGATGGCCTGGATAAGATAATTAAATCCAGGATTGATAATAAAGTGATGGGTTTCGG
GGCAGACATTAAGAGCAAGACTGAAGAAAATGTCGGGGAAACCCTGAAATATATCCTGCCTGAAGATTTACTGCGCTACG
GGTTAATTCCTGAATTTATCGGTAGGTTGCCGGTAATTGTTACTCTGAATGAACTGGTTGAAGAAGACCTGGTTAAGATT
TTGACCGAGCCCCGTAACGCGCTGGTTAAACAGTACAAGAAGTTCTTTGAAATGGATAATGTAGAGCTTGAGTTTACTCC
AGAGGCCTTAACGGCAATTGCCCAGAAGGCCCTTGAAAGAAATACTGGAGCCCGTGGTTTGAGGGCTGTTGTTGAAGAAG
CTATCCTTGATATAATGTATGACCTTCCTTCAGAACCCGGTATTGCTAAATGTGTTATTACACCTGAAGTAATTAAAAAC
CACAAAAACCCTGAATTAATCAGGGTTAAGGATAAAGAAGAGACCGCTTAA

Upstream 100 bases:

>100_bases
ATTTTATGACAGCAGAAGAGGCCCTTGAATATGGTATTATTGATGAGGTAATTACCAAGAACGAATTAAAAGATAAGTAA
CTCTTTCAAGAGGTGATATA

Downstream 100 bases:

>100_bases
GAAAAAAACTTGCCCCCTGAGGATAAAAATGCCAGATAAGGATATACTATTTTTTGAAGTTTAAGTGAAAAGGGGGCAAA
GTTGGTGGATCAAAATCTCT

Product: ATP-dependent Clp protease, ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MFKFGDEKGQLKCSFCGKSQEQVRKLVAGPGVYICDECIELCNEIIEEELNDDVEFNLNNIPKPREIKKILDQYVVGQER
AKKSLSVAVYNHYKRVNSDMKIDDVELQKSNILMVGPTGCGKTLLAQTLARILDVPFAITDATSLTEAGYVGEDVENILL
KLIQAADYDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFIAGGAFDGLDKIIKSRIDNKVMGFGADIKSKTEENVGETLKYILPEDLLRYGLIPEFIGRLPVIVTLNELVEEDLVKI
LTEPRNALVKQYKKFFEMDNVELEFTPEALTAIAQKALERNTGARGLRAVVEEAILDIMYDLPSEPGIAKCVITPEVIKN
HKNPELIRVKDKEETA

Sequences:

>Translated_416_residues
MFKFGDEKGQLKCSFCGKSQEQVRKLVAGPGVYICDECIELCNEIIEEELNDDVEFNLNNIPKPREIKKILDQYVVGQER
AKKSLSVAVYNHYKRVNSDMKIDDVELQKSNILMVGPTGCGKTLLAQTLARILDVPFAITDATSLTEAGYVGEDVENILL
KLIQAADYDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFIAGGAFDGLDKIIKSRIDNKVMGFGADIKSKTEENVGETLKYILPEDLLRYGLIPEFIGRLPVIVTLNELVEEDLVKI
LTEPRNALVKQYKKFFEMDNVELEFTPEALTAIAQKALERNTGARGLRAVVEEAILDIMYDLPSEPGIAKCVITPEVIKN
HKNPELIRVKDKEETA
>Mature_416_residues
MFKFGDEKGQLKCSFCGKSQEQVRKLVAGPGVYICDECIELCNEIIEEELNDDVEFNLNNIPKPREIKKILDQYVVGQER
AKKSLSVAVYNHYKRVNSDMKIDDVELQKSNILMVGPTGCGKTLLAQTLARILDVPFAITDATSLTEAGYVGEDVENILL
KLIQAADYDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFIAGGAFDGLDKIIKSRIDNKVMGFGADIKSKTEENVGETLKYILPEDLLRYGLIPEFIGRLPVIVTLNELVEEDLVKI
LTEPRNALVKQYKKFFEMDNVELEFTPEALTAIAQKALERNTGARGLRAVVEEAILDIMYDLPSEPGIAKCVITPEVIKN
HKNPELIRVKDKEETA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=342, Percent_Identity=50, Blast_Score=322, Evalue=5e-88,
Organism=Escherichia coli, GI1786642, Length=409, Percent_Identity=63.3251833740831, Blast_Score=532, Evalue=1e-152,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=35.2112676056338, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=323, Percent_Identity=47.0588235294118, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71982905, Length=325, Percent_Identity=47.3846153846154, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI71988663, Length=412, Percent_Identity=39.8058252427184, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=39.84375, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=412, Percent_Identity=41.0194174757282, Blast_Score=281, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24648289, Length=330, Percent_Identity=47.8787878787879, Blast_Score=307, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24648291, Length=330, Percent_Identity=47.8787878787879, Blast_Score=307, Evalue=9e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_HALOH (B8CY73)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002509237.1
- ProteinModelPortal:   B8CY73
- GeneID:   7313084
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_14930
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   CLSK2806467
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46447; Mature: 46447

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFGDEKGQLKCSFCGKSQEQVRKLVAGPGVYICDECIELCNEIIEEELNDDVEFNLNN
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCC
IPKPREIKKILDQYVVGQERAKKSLSVAVYNHYKRVNSDMKIDDVELQKSNILMVGPTGC
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCC
GKTLLAQTLARILDVPFAITDATSLTEAGYVGEDVENILLKLIQAADYDIEKAERGIIYI
CHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFIAGGAFDGLDKIIKSRIDNKVMGFGADIKSKTEENVGETLKYILPEDLLRYGLIPEFI
EEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHH
GRLPVIVTLNELVEEDLVKILTEPRNALVKQYKKFFEMDNVELEFTPEALTAIAQKALER
CCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
NTGARGLRAVVEEAILDIMYDLPSEPGIAKCVITPEVIKNHKNPELIRVKDKEETA
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MFKFGDEKGQLKCSFCGKSQEQVRKLVAGPGVYICDECIELCNEIIEEELNDDVEFNLNN
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCC
IPKPREIKKILDQYVVGQERAKKSLSVAVYNHYKRVNSDMKIDDVELQKSNILMVGPTGC
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCC
GKTLLAQTLARILDVPFAITDATSLTEAGYVGEDVENILLKLIQAADYDIEKAERGIIYI
CHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFIAGGAFDGLDKIIKSRIDNKVMGFGADIKSKTEENVGETLKYILPEDLLRYGLIPEFI
EEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHH
GRLPVIVTLNELVEEDLVKILTEPRNALVKQYKKFFEMDNVELEFTPEALTAIAQKALER
CCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
NTGARGLRAVVEEAILDIMYDLPSEPGIAKCVITPEVIKNHKNPELIRVKDKEETA
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA