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The map label for this gene is yqgX [H]

Identifier: 220932054

GI number: 220932054

Start: 1310676

End: 1311308

Strand: Reverse

Name: yqgX [H]

Synonym: Hore_12170

Alternate gene names: 220932054

Gene position: 1311308-1310676 (Counterclockwise)

Preceding gene: 220932055

Following gene: 220932053

Centisome position: 50.86

GC content: 37.6

Gene sequence:

>633_bases
TTGATTTTTAAGAGAGTACCGGTCGGGGTCAATTATACTAACTCCTATATAATAGGACAGGAAGATGGTAATGGAATAAT
AGTAGACCCCGGTGATGAAGCACGGAAATTACTTTCTTCAGTTGAGGATTTGAAGATTAATTTGACAAAAATAATCATTA
CACATGCCCATTTTGACCATATAGGAGCGGTAGAGTATTTGAGGGAAGAGACCGGGGCTGAGGTTTTGATACATGAAAAG
GAAAATGAATTTTTGAAGGATCCTGATAAAAATCTTTCCTTTCTTATCGGAAAGGAAATTGTTTGCCAGGGAGCAGATAC
TTTACTGGGTGATGGTGATGTTATCGGGGTAAGTAATGGGCTGTCATTTGAAGTAATTTTTACTCCTGGACATAGTCCCG
GTGGTATCTGTCTCTATAATAAGGAAGATAACTATTTACTGAGTGGTGATACTATTTTTTTCAGGGGAGTAGGGAGAACT
GATTTTCAATTTGGAAATGAAAAAAAACTCATACAGTCAATTGAAAATAAAATCCTGATTCTCCCTGAAGATACAGTTGT
TTACCCGGGTCATGGTGCCAGCACGACTATTGGTGATTTTAAAAATAATTACTGGGAGACAGCAAGGGGATAA

Upstream 100 bases:

>100_bases
AAGGCGTATTTCAGGCAATGATGGAAGTAAATCTAATAAATGATGGACCTGTAACCATTTTACTTGATAGTAATAAACAA
TTTTAAGGTGGTGACCTTAT

Downstream 100 bases:

>100_bases
GTTGACATTGCCGTTTTAATAGGTTAAAATGATTAAAGGTTAAACTTTTCTTGTAGTAGTAAATTATGTAATGATATAGT
TTTCACTTTTTATTTCTGAA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIFKRVPVGVNYTNSYIIGQEDGNGIIVDPGDEARKLLSSVEDLKINLTKIIITHAHFDHIGAVEYLREETGAEVLIHEK
ENEFLKDPDKNLSFLIGKEIVCQGADTLLGDGDVIGVSNGLSFEVIFTPGHSPGGICLYNKEDNYLLSGDTIFFRGVGRT
DFQFGNEKKLIQSIENKILILPEDTVVYPGHGASTTIGDFKNNYWETARG

Sequences:

>Translated_210_residues
MIFKRVPVGVNYTNSYIIGQEDGNGIIVDPGDEARKLLSSVEDLKINLTKIIITHAHFDHIGAVEYLREETGAEVLIHEK
ENEFLKDPDKNLSFLIGKEIVCQGADTLLGDGDVIGVSNGLSFEVIFTPGHSPGGICLYNKEDNYLLSGDTIFFRGVGRT
DFQFGNEKKLIQSIENKILILPEDTVVYPGHGASTTIGDFKNNYWETARG
>Mature_210_residues
MIFKRVPVGVNYTNSYIIGQEDGNGIIVDPGDEARKLLSSVEDLKINLTKIIITHAHFDHIGAVEYLREETGAEVLIHEK
ENEFLKDPDKNLSFLIGKEIVCQGADTLLGDGDVIGVSNGLSFEVIFTPGHSPGGICLYNKEDNYLLSGDTIFFRGVGRT
DFQFGNEKKLIQSIENKILILPEDTVVYPGHGASTTIGDFKNNYWETARG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=187, Percent_Identity=31.5508021390374, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1787158, Length=201, Percent_Identity=37.3134328358209, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786406, Length=176, Percent_Identity=34.0909090909091, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=209, Percent_Identity=32.0574162679426, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221330176, Length=210, Percent_Identity=30, Blast_Score=97, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23191; Mature: 23191

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKRVPVGVNYTNSYIIGQEDGNGIIVDPGDEARKLLSSVEDLKINLTKIIITHAHFDH
CCEEECCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHCEEEEEEEEEEECCCCH
IGAVEYLREETGAEVLIHEKENEFLKDPDKNLSFLIGKEIVCQGADTLLGDGDVIGVSNG
HHHHHHHHHHCCCEEEEECCCCCHHCCCCCCCEEEECCEEEECCCCEEECCCCEEEECCC
LSFEVIFTPGHSPGGICLYNKEDNYLLSGDTIFFRGVGRTDFQFGNEKKLIQSIENKILI
CEEEEEEECCCCCCCEEEEECCCCEEEECCEEEEEECCCCCCCCCCHHHHHHHHCCCEEE
LPEDTVVYPGHGASTTIGDFKNNYWETARG
EECCCEEECCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MIFKRVPVGVNYTNSYIIGQEDGNGIIVDPGDEARKLLSSVEDLKINLTKIIITHAHFDH
CCEEECCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHCEEEEEEEEEEECCCCH
IGAVEYLREETGAEVLIHEKENEFLKDPDKNLSFLIGKEIVCQGADTLLGDGDVIGVSNG
HHHHHHHHHHCCCEEEEECCCCCHHCCCCCCCEEEECCEEEECCCCEEECCCCEEEECCC
LSFEVIFTPGHSPGGICLYNKEDNYLLSGDTIFFRGVGRTDFQFGNEKKLIQSIENKILI
CEEEEEEECCCCCCCEEEEECCCCEEEECCEEEEEECCCCCCCCCCHHHHHHHHCCCEEE
LPEDTVVYPGHGASTTIGDFKNNYWETARG
EECCCEEECCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]