Click here to switch to the map view.

The map label for this gene is hfq [H]

Identifier: 220931997

GI number: 220931997

Start: 1250385

End: 1250615

Strand: Reverse

Name: hfq [H]

Synonym: Hore_11580

Alternate gene names: 220931997

Gene position: 1250615-1250385 (Counterclockwise)

Preceding gene: 220931998

Following gene: 220931996

Centisome position: 48.51

GC content: 32.47

Gene sequence:

>231_bases
ATGAAAAACCAGTTTAATCTTCAGGATAACCTTTTAAATCAGGTCAGGAAAAAGAATGTTCCGGTAGTTATATACCTTGT
TAATGGCTTTCAAATCAAAGGTAAAGTTACCGGTTTTGATAATTTTACTATTTTAATTAACAGTGAAGGAAAGGACCAGA
TGGTGTATAAACATGCAATTTCAACTATCATACCACAGGAAAAGGTGGATATCCAGTTAAGTTCAGAGTAA

Upstream 100 bases:

>100_bases
ATTGTTTAATATGTGGTGATAAAAAATGAAAATTTAAGCAGGACTTTTTATAAAAATGTAGAATAAAAAGTATAACAGAA
ATAGAAGGGAGCATCTTATT

Downstream 100 bases:

>100_bases
AGGTGGGTATTAAATGGAACTAAGTTTTACAAAAATGCATGGAACTGGAAATGATTTTATTATGGTAAATGGTAGTAACT
ATCCTGATTTAGATTTTAGT

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 76; Mature: 76

Protein sequence:

>76_residues
MKNQFNLQDNLLNQVRKKNVPVVIYLVNGFQIKGKVTGFDNFTILINSEGKDQMVYKHAISTIIPQEKVDIQLSSE

Sequences:

>Translated_76_residues
MKNQFNLQDNLLNQVRKKNVPVVIYLVNGFQIKGKVTGFDNFTILINSEGKDQMVYKHAISTIIPQEKVDIQLSSE
>Mature_76_residues
MKNQFNLQDNLLNQVRKKNVPVVIYLVNGFQIKGKVTGFDNFTILINSEGKDQMVYKHAISTIIPQEKVDIQLSSE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=65, Percent_Identity=50.7692307692308, Blast_Score=72, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8694; Mature: 8694

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQFNLQDNLLNQVRKKNVPVVIYLVNGFQIKGKVTGFDNFTILINSEGKDQMVYKHAI
CCCCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCCHHHHHHHH
STIIPQEKVDIQLSSE
HHHCCCCCEEEEEECC
>Mature Secondary Structure
MKNQFNLQDNLLNQVRKKNVPVVIYLVNGFQIKGKVTGFDNFTILINSEGKDQMVYKHAI
CCCCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCCHHHHHHHH
STIIPQEKVDIQLSSE
HHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA