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The map label for this gene is exuR [H]

Identifier: 220931787

GI number: 220931787

Start: 1016560

End: 1017654

Strand: Direct

Name: exuR [H]

Synonym: Hore_09440

Alternate gene names: 220931787

Gene position: 1016560-1017654 (Clockwise)

Preceding gene: 220931786

Following gene: 220931788

Centisome position: 39.43

GC content: 35.25

Gene sequence:

>1095_bases
ATGAAAAAGGTAACCCAACAGGATATTGCTGATATGCTTGGTATTTCCAGGACTACTGTTGCCCGGGCCTTGAACGGAAC
CGGACCAGTGGATGAAAACACCAGGAAAAAGGTAATAGAAACAGCCCGAAAGCTTAATTATCAAATTAATCCGATTGCCA
GGACCCTGGCCCGTCAGAAAACAGTGGGGGTCAGTGTTTTTTGCGCTAAAACAAGTAATGATCATTTTAATCATCATATT
GAAGCTGGTTTTAATCTTGCTTTTAATGAATTTAAACATTTTGGGGTAAAATATAATCTCTACTGGACCAGTACTGAAGA
CCCGGATAAACAGGTTGAAAAAATGTATGCAGTGTTAGAAAAAGATAAAGATATAGATGGGGTAATTGTTATGCCTTTGA
ATGTGGAGAAAGTTAAAGAAATCGCCCGGGTCTGTAAAGAAAAAAATATTGAATTTGGTACGGTAAATATGGATATTGAT
TGTGATGATAGATTATTTTTTGTTGGTAATGATGACTATAGTGGAGGGAGAATAGCAGGTGACATTTTATCTAACCTCCT
TACTGGAAGAGGCAATATAGCCATTATAGGGTCTGTTTATCAGTATGTTTCTTCTTATAAAAGGCTTAAGGGTTTTATGG
ACATTGTAATGGAAAGATCTCATCTCGATATAAGTACCTGGCAGAATGTTAAAGACCTGGATGAAGCCTATAAAATAACC
AAACAGATACTTAAGGAAAAGACAGACATACATGGGATTTTTACTACAGTAGAAATTCTTTATGTAGCCCGGGCCCTTAA
AGAATTGGGTAAAAGAGATGTAGTTTTAGTGGGTTATGATCTTAATAAAAAAGTGAAGTCTTACATTAAGCAAGGAATTA
TTAATTCGGTGTTGTATCAACGCCCCTTTCTTCAGGGGTATCTTGCCCTTAAGTATATGTTAAACTATTTAATTTATGAA
AATACTACCCCCACTAAAGAAGTGACCATTGGATATGATATAGTTACTAAAGAGAATTTAAAGGTGGAGGAGCTTTATTT
AAAAAACTTTTTACAACAACCTGTTTATGATACTGAGAGAACCCAAATTAAATAG

Upstream 100 bases:

>100_bases
GATTTTCGTAGCTTTAAAATTCCACGTTAATCCTTGACTATGGTATTTAAATTAATTTTAGGCTAGATAACTGGAATTAG
TTAAAAGGGGTAATGTTGTT

Downstream 100 bases:

>100_bases
GGATTCTGGTCGCGAGTACAATTAATAAAAAACATAATTTAGATGATTTTGATTAGTTTTTAAAAATTGTTGACAAATTT
CTTTAAATTAAATAAAATAT

Product: regulatory protein LacI

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKKVTQQDIADMLGISRTTVARALNGTGPVDENTRKKVIETARKLNYQINPIARTLARQKTVGVSVFCAKTSNDHFNHHI
EAGFNLAFNEFKHFGVKYNLYWTSTEDPDKQVEKMYAVLEKDKDIDGVIVMPLNVEKVKEIARVCKEKNIEFGTVNMDID
CDDRLFFVGNDDYSGGRIAGDILSNLLTGRGNIAIIGSVYQYVSSYKRLKGFMDIVMERSHLDISTWQNVKDLDEAYKIT
KQILKEKTDIHGIFTTVEILYVARALKELGKRDVVLVGYDLNKKVKSYIKQGIINSVLYQRPFLQGYLALKYMLNYLIYE
NTTPTKEVTIGYDIVTKENLKVEELYLKNFLQQPVYDTERTQIK

Sequences:

>Translated_364_residues
MKKVTQQDIADMLGISRTTVARALNGTGPVDENTRKKVIETARKLNYQINPIARTLARQKTVGVSVFCAKTSNDHFNHHI
EAGFNLAFNEFKHFGVKYNLYWTSTEDPDKQVEKMYAVLEKDKDIDGVIVMPLNVEKVKEIARVCKEKNIEFGTVNMDID
CDDRLFFVGNDDYSGGRIAGDILSNLLTGRGNIAIIGSVYQYVSSYKRLKGFMDIVMERSHLDISTWQNVKDLDEAYKIT
KQILKEKTDIHGIFTTVEILYVARALKELGKRDVVLVGYDLNKKVKSYIKQGIINSVLYQRPFLQGYLALKYMLNYLIYE
NTTPTKEVTIGYDIVTKENLKVEELYLKNFLQQPVYDTERTQIK
>Mature_364_residues
MKKVTQQDIADMLGISRTTVARALNGTGPVDENTRKKVIETARKLNYQINPIARTLARQKTVGVSVFCAKTSNDHFNHHI
EAGFNLAFNEFKHFGVKYNLYWTSTEDPDKQVEKMYAVLEKDKDIDGVIVMPLNVEKVKEIARVCKEKNIEFGTVNMDID
CDDRLFFVGNDDYSGGRIAGDILSNLLTGRGNIAIIGSVYQYVSSYKRLKGFMDIVMERSHLDISTWQNVKDLDEAYKIT
KQILKEKTDIHGIFTTVEILYVARALKELGKRDVVLVGYDLNKKVKSYIKQGIINSVLYQRPFLQGYLALKYMLNYLIYE
NTTPTKEVTIGYDIVTKENLKVEELYLKNFLQQPVYDTERTQIK

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=337, Percent_Identity=24.3323442136499, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 41763; Mature: 41763

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVTQQDIADMLGISRTTVARALNGTGPVDENTRKKVIETARKLNYQINPIARTLARQK
CCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TVGVSVFCAKTSNDHFNHHIEAGFNLAFNEFKHFGVKYNLYWTSTEDPDKQVEKMYAVLE
CCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHH
KDKDIDGVIVMPLNVEKVKEIARVCKEKNIEFGTVNMDIDCDDRLFFVGNDDYSGGRIAG
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCEEHH
DILSNLLTGRGNIAIIGSVYQYVSSYKRLKGFMDIVMERSHLDISTWQNVKDLDEAYKIT
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHH
KQILKEKTDIHGIFTTVEILYVARALKELGKRDVVLVGYDLNKKVKSYIKQGIINSVLYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RPFLQGYLALKYMLNYLIYENTTPTKEVTIGYDIVTKENLKVEELYLKNFLQQPVYDTER
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCC
TQIK
CCCC
>Mature Secondary Structure
MKKVTQQDIADMLGISRTTVARALNGTGPVDENTRKKVIETARKLNYQINPIARTLARQK
CCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TVGVSVFCAKTSNDHFNHHIEAGFNLAFNEFKHFGVKYNLYWTSTEDPDKQVEKMYAVLE
CCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHH
KDKDIDGVIVMPLNVEKVKEIARVCKEKNIEFGTVNMDIDCDDRLFFVGNDDYSGGRIAG
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCCEEHH
DILSNLLTGRGNIAIIGSVYQYVSSYKRLKGFMDIVMERSHLDISTWQNVKDLDEAYKIT
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHH
KQILKEKTDIHGIFTTVEILYVARALKELGKRDVVLVGYDLNKKVKSYIKQGIINSVLYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RPFLQGYLALKYMLNYLIYENTTPTKEVTIGYDIVTKENLKVEELYLKNFLQQPVYDTER
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCC
TQIK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]