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The map label for this gene is macB2 [H]

Identifier: 220931105

GI number: 220931105

Start: 263081

End: 264334

Strand: Direct

Name: macB2 [H]

Synonym: Hore_02570

Alternate gene names: 220931105

Gene position: 263081-264334 (Clockwise)

Preceding gene: 220931104

Following gene: 220931106

Centisome position: 10.2

GC content: 42.58

Gene sequence:

>1254_bases
ATGAATTTAATGGAAACAATTAGACTGGCCCTGGCCGGGGTTGGAAGTAATAAATTGAGGTCATTTTTGACCCTGTTAGG
TATTATAATTGGAGTAACAGCAGTTATTCTGATGGTATCTCTGGGGAGTGGAACCCAGAAGGTTGTTAGTGGCCAGTTCA
GTAATCTTCAGACCCGTCAAATATATATAGATGAAAACCATAATTTACCATACCATCTGCAGGGGCGGTTAAGTTTGCGG
GACAGGGATTACCTTAAAGACTCTGTAATGGGTGTTGAAAAGGTCGTTCCCTTTTACCAGCTTTACACGGGGGTAAAGTA
TGGTGATAATGAGCAGGAAGGCTGGGTTTATGGTATCGATCCTGCTTCACAGGAACTGATTAATGTAAATATAAGTTATG
GCCGTTTTTTTGACCAGTCAGATATTGATAATAAAGAGCGGGTTGCTATAGTCGGGGAACAGTTGCTGGAAAGACTGGCG
AGGACAGGAAATATGGTGCAACCACAACACGCCTCTACCCCCGATTATGCCTCAGCAGTCGGTAAATATATATATCTGTC
TGGTAAGAAATTTATTATTGTTGGAGTTATGCAGGAATCCCAGAACATGATGTTTATTTCTAATCAATCGGTTCTACTTC
CATACACCACTATCAGAGACCACTGGCGCCGGGAAACCAGATATGTAGATTTTTATCTGCTATCCTATGGTCCAGACGCT
TCAGAGAAAGATACCCTGGAACAGGTAAAATATCTTATGGATAGAAAATACGGTAAAACCAGTACCGGGAAGAGTAAGTT
TTACTTCCAGAGTCTTCAGGAAAATGTCAATATCATGACCAGGGTTTTTACTGTATTTACTTATGTGCTTGGTGGAATTG
CTTCTATTTCCCTGCTGGTAGGCGGTATCGGGGTTATGAATATTATGCTGGTTACCGTTAAAGAAAGGACCCGTGAGATT
GGAGTAAGGCTGGCCATAGGAGCGACCAGGCAGGATGTTCAGAGACAGTTTTTAGCAGAATCAGTCATCCTCTCTGTCGG
TGGTGGTATTGTCGGGGTTTTAATGGGTAGTATTCTTTCATTTCTTGCCAATATGATCTTGAAACAGGTCTTCAACTGGT
GGCAGGGATTTATTCCAGGGTGGGTTATTCTGCTATCCTTCGGGGTAACTACCGCCATTGGGGTTATATTTGGTTTTTAT
CCTGCCTATAAGGCCTCCAGGCTTGACCCCATAGAGGCTCTAAGATATGAATAG

Upstream 100 bases:

>100_bases
ACGACACTGGTTGGTCTCTTCTTTGGAATATACCCTGCCTATAAAGCAGCCCGCCTTAATCCCATAGAGGCGTTGCGTTA
TGAATAAGGTGGTGACATAG

Downstream 100 bases:

>100_bases
TTTTTTAATGTTTTTTACTTAAATTGAGGAGGTAGATAGAATGTCACCATGGAGCAAAATGGTTAATATTTTTCTTTCCC
CTGAAGAAGTTTTCATGGAT

Product: antimicrobial peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNLMETIRLALAGVGSNKLRSFLTLLGIIIGVTAVILMVSLGSGTQKVVSGQFSNLQTRQIYIDENHNLPYHLQGRLSLR
DRDYLKDSVMGVEKVVPFYQLYTGVKYGDNEQEGWVYGIDPASQELINVNISYGRFFDQSDIDNKERVAIVGEQLLERLA
RTGNMVQPQHASTPDYASAVGKYIYLSGKKFIIVGVMQESQNMMFISNQSVLLPYTTIRDHWRRETRYVDFYLLSYGPDA
SEKDTLEQVKYLMDRKYGKTSTGKSKFYFQSLQENVNIMTRVFTVFTYVLGGIASISLLVGGIGVMNIMLVTVKERTREI
GVRLAIGATRQDVQRQFLAESVILSVGGGIVGVLMGSILSFLANMILKQVFNWWQGFIPGWVILLSFGVTTAIGVIFGFY
PAYKASRLDPIEALRYE

Sequences:

>Translated_417_residues
MNLMETIRLALAGVGSNKLRSFLTLLGIIIGVTAVILMVSLGSGTQKVVSGQFSNLQTRQIYIDENHNLPYHLQGRLSLR
DRDYLKDSVMGVEKVVPFYQLYTGVKYGDNEQEGWVYGIDPASQELINVNISYGRFFDQSDIDNKERVAIVGEQLLERLA
RTGNMVQPQHASTPDYASAVGKYIYLSGKKFIIVGVMQESQNMMFISNQSVLLPYTTIRDHWRRETRYVDFYLLSYGPDA
SEKDTLEQVKYLMDRKYGKTSTGKSKFYFQSLQENVNIMTRVFTVFTYVLGGIASISLLVGGIGVMNIMLVTVKERTREI
GVRLAIGATRQDVQRQFLAESVILSVGGGIVGVLMGSILSFLANMILKQVFNWWQGFIPGWVILLSFGVTTAIGVIFGFY
PAYKASRLDPIEALRYE
>Mature_417_residues
MNLMETIRLALAGVGSNKLRSFLTLLGIIIGVTAVILMVSLGSGTQKVVSGQFSNLQTRQIYIDENHNLPYHLQGRLSLR
DRDYLKDSVMGVEKVVPFYQLYTGVKYGDNEQEGWVYGIDPASQELINVNISYGRFFDQSDIDNKERVAIVGEQLLERLA
RTGNMVQPQHASTPDYASAVGKYIYLSGKKFIIVGVMQESQNMMFISNQSVLLPYTTIRDHWRRETRYVDFYLLSYGPDA
SEKDTLEQVKYLMDRKYGKTSTGKSKFYFQSLQENVNIMTRVFTVFTYVLGGIASISLLVGGIGVMNIMLVTVKERTREI
GVRLAIGATRQDVQRQFLAESVILSVGGGIVGVLMGSILSFLANMILKQVFNWWQGFIPGWVILLSFGVTTAIGVIFGFY
PAYKASRLDPIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=430, Percent_Identity=29.0697674418605, Blast_Score=155, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46866; Mature: 46866

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMETIRLALAGVGSNKLRSFLTLLGIIIGVTAVILMVSLGSGTQKVVSGQFSNLQTRQ
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEE
IYIDENHNLPYHLQGRLSLRDRDYLKDSVMGVEKVVPFYQLYTGVKYGDNEQEGWVYGID
EEEECCCCCCEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
PASQELINVNISYGRFFDQSDIDNKERVAIVGEQLLERLARTGNMVQPQHASTPDYASAV
CCCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
GKYIYLSGKKFIIVGVMQESQNMMFISNQSVLLPYTTIRDHWRRETRYVDFYLLSYGPDA
CCEEEECCCEEEEEEEEECCCCEEEEECCCEEEEHHHHHHHHHHHCEEEEEEEEEECCCC
SEKDTLEQVKYLMDRKYGKTSTGKSKFYFQSLQENVNIMTRVFTVFTYVLGGIASISLLV
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGVMNIMLVTVKERTREIGVRLAIGATRQDVQRQFLAESVILSVGGGIVGVLMGSILS
HHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FLANMILKQVFNWWQGFIPGWVILLSFGVTTAIGVIFGFYPAYKASRLDPIEALRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure
MNLMETIRLALAGVGSNKLRSFLTLLGIIIGVTAVILMVSLGSGTQKVVSGQFSNLQTRQ
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEE
IYIDENHNLPYHLQGRLSLRDRDYLKDSVMGVEKVVPFYQLYTGVKYGDNEQEGWVYGID
EEEECCCCCCEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
PASQELINVNISYGRFFDQSDIDNKERVAIVGEQLLERLARTGNMVQPQHASTPDYASAV
CCCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
GKYIYLSGKKFIIVGVMQESQNMMFISNQSVLLPYTTIRDHWRRETRYVDFYLLSYGPDA
CCEEEECCCEEEEEEEEECCCCEEEEECCCEEEEHHHHHHHHHHHCEEEEEEEEEECCCC
SEKDTLEQVKYLMDRKYGKTSTGKSKFYFQSLQENVNIMTRVFTVFTYVLGGIASISLLV
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGVMNIMLVTVKERTREIGVRLAIGATRQDVQRQFLAESVILSVGGGIVGVLMGSILS
HHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FLANMILKQVFNWWQGFIPGWVILLSFGVTTAIGVIFGFYPAYKASRLDPIEALRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA