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The map label for this gene is macB2 [H]

Identifier: 220931104

GI number: 220931104

Start: 261847

End: 263067

Strand: Direct

Name: macB2 [H]

Synonym: Hore_02560

Alternate gene names: 220931104

Gene position: 261847-263067 (Clockwise)

Preceding gene: 220931103

Following gene: 220931105

Centisome position: 10.16

GC content: 42.34

Gene sequence:

>1221_bases
ATGAAATTACTTGAGTATATTGGTCTTGCCCTGTATGAAATCTGGCATAATAAGGTCAGGACCTTTTTGACCCTGATTGG
GGTCATTATCGGGATAGCTGCTGTAATTGTTATTATTTTTGTGGTCCAGGGGGCAGAGAGGTTTTTACTGGCTGAAGTTG
AAAAAATAGCTCCTTCTGATGTTATCTATGCTTATGCCCGGTGGGACCGTGATACCAGACGGCCTATGGCTGGGTTGACC
CTTGATGATATTGAGTATATTAAAGACAGGGAATCAGACATGATTAGAGCCATTGCCCCCCGGTATTATGGTAACAGTAA
GATCAGACTTAATGGGGAAGAAAAGGATTGCAACCTCATTGCTTCAACCCCCTCTATCTTTGATATATATGATGTAAGTA
TTGCCAGAGGAAGGTCCTTAACACGGCTGGATATGGAAGAATTAAATCAGGTGGTTGTCCTGAGTTATGATACAGCTGAA
AAATTATTTGAAGGGGTTAACCCTGTTGGTAAGAAGTTAAATCTGTCCGGTCTTACTTTTACCGTCATCGGTGTCCTGGA
GGAGGGGGAAAAGTCCATAATCCCTACTTCAGTAACAAATAATACGGTATTTATCCCTTTTAGTGTATTTGAAAGGATTT
TTGATGTTCATAACCGCTTTATCTTAATGGCCAGGCTAAAAGATAAATCTCTGGTCGATACAGGAATTAAGCGGGTACAA
CAATTACTGGACAGAAGGCATGGTATGGCAGACAATGGGATGTCAAAGTTTCGAGTAAGTAGCTGGGTCTCAGGGCTTAA
GGAAATAAGTATTATAAAGACGGTCCTGATTGTCTTACTTAGCGGGGTCGCCAGTATAACCCTTCTGGTGGCCGGGATTG
GTTTAATGAACATTATGCTGGTTATTGTAACTGAAAGGACCCGGGAGATTGGCCTGAGGAAGGCCCTGGGGGCAACAAAC
CGGGATATCCTCATTCAATTTATTATTGAATCCATTGTTCTCTGTATTGTTGGAGGTATTCTCGGGGTTATTGTAGGGTA
TCTCGGGAGTGAAGTTGCCCTCAATATTGCTAATAAATACATTAACTTTAGTTATAGTGTCCCAAGGTGGGCAGTTTTGC
TGTCCCTGACCTTTACGACACTGGTTGGTCTCTTCTTTGGAATATACCCTGCCTATAAAGCAGCCCGCCTTAATCCCATA
GAGGCGTTGCGTTATGAATAA

Upstream 100 bases:

>100_bases
CACCGTATAGTCCATTTTAAAGATGGAGAGATAATCAGGGAAGATAAAACACAGAACGGTATTAATAGAGAGACTGCTAC
CCGTTCCTGGAGGGATCGGG

Downstream 100 bases:

>100_bases
GGTGGTGACATAGATGAATTTAATGGAAACAATTAGACTGGCCCTGGCCGGGGTTGGAAGTAATAAATTGAGGTCATTTT
TGACCCTGTTAGGTATTATA

Product: antimicrobial peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKLLEYIGLALYEIWHNKVRTFLTLIGVIIGIAAVIVIIFVVQGAERFLLAEVEKIAPSDVIYAYARWDRDTRRPMAGLT
LDDIEYIKDRESDMIRAIAPRYYGNSKIRLNGEEKDCNLIASTPSIFDIYDVSIARGRSLTRLDMEELNQVVVLSYDTAE
KLFEGVNPVGKKLNLSGLTFTVIGVLEEGEKSIIPTSVTNNTVFIPFSVFERIFDVHNRFILMARLKDKSLVDTGIKRVQ
QLLDRRHGMADNGMSKFRVSSWVSGLKEISIIKTVLIVLLSGVASITLLVAGIGLMNIMLVIVTERTREIGLRKALGATN
RDILIQFIIESIVLCIVGGILGVIVGYLGSEVALNIANKYINFSYSVPRWAVLLSLTFTTLVGLFFGIYPAYKAARLNPI
EALRYE

Sequences:

>Translated_406_residues
MKLLEYIGLALYEIWHNKVRTFLTLIGVIIGIAAVIVIIFVVQGAERFLLAEVEKIAPSDVIYAYARWDRDTRRPMAGLT
LDDIEYIKDRESDMIRAIAPRYYGNSKIRLNGEEKDCNLIASTPSIFDIYDVSIARGRSLTRLDMEELNQVVVLSYDTAE
KLFEGVNPVGKKLNLSGLTFTVIGVLEEGEKSIIPTSVTNNTVFIPFSVFERIFDVHNRFILMARLKDKSLVDTGIKRVQ
QLLDRRHGMADNGMSKFRVSSWVSGLKEISIIKTVLIVLLSGVASITLLVAGIGLMNIMLVIVTERTREIGLRKALGATN
RDILIQFIIESIVLCIVGGILGVIVGYLGSEVALNIANKYINFSYSVPRWAVLLSLTFTTLVGLFFGIYPAYKAARLNPI
EALRYE
>Mature_406_residues
MKLLEYIGLALYEIWHNKVRTFLTLIGVIIGIAAVIVIIFVVQGAERFLLAEVEKIAPSDVIYAYARWDRDTRRPMAGLT
LDDIEYIKDRESDMIRAIAPRYYGNSKIRLNGEEKDCNLIASTPSIFDIYDVSIARGRSLTRLDMEELNQVVVLSYDTAE
KLFEGVNPVGKKLNLSGLTFTVIGVLEEGEKSIIPTSVTNNTVFIPFSVFERIFDVHNRFILMARLKDKSLVDTGIKRVQ
QLLDRRHGMADNGMSKFRVSSWVSGLKEISIIKTVLIVLLSGVASITLLVAGIGLMNIMLVIVTERTREIGLRKALGATN
RDILIQFIIESIVLCIVGGILGVIVGYLGSEVALNIANKYINFSYSVPRWAVLLSLTFTTLVGLFFGIYPAYKAARLNPI
EALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=405, Percent_Identity=31.1111111111111, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45390; Mature: 45390

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEYIGLALYEIWHNKVRTFLTLIGVIIGIAAVIVIIFVVQGAERFLLAEVEKIAPSD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
VIYAYARWDRDTRRPMAGLTLDDIEYIKDRESDMIRAIAPRYYGNSKIRLNGEEKDCNLI
HEEEHHHCCCHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEE
ASTPSIFDIYDVSIARGRSLTRLDMEELNQVVVLSYDTAEKLFEGVNPVGKKLNLSGLTF
ECCCCEEEEEECHHHCCCCCCCCCHHHCCCEEEEEECCHHHHHHCCCCCCCCEECCCCCE
TVIGVLEEGEKSIIPTSVTNNTVFIPFSVFERIFDVHNRFILMARLKDKSLVDTGIKRVQ
EEEEEHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHH
QLLDRRHGMADNGMSKFRVSSWVSGLKEISIIKTVLIVLLSGVASITLLVAGIGLMNIML
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVTERTREIGLRKALGATNRDILIQFIIESIVLCIVGGILGVIVGYLGSEVALNIANKY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
INFSYSVPRWAVLLSLTFTTLVGLFFGIYPAYKAARLNPIEALRYE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MKLLEYIGLALYEIWHNKVRTFLTLIGVIIGIAAVIVIIFVVQGAERFLLAEVEKIAPSD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
VIYAYARWDRDTRRPMAGLTLDDIEYIKDRESDMIRAIAPRYYGNSKIRLNGEEKDCNLI
HEEEHHHCCCHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEE
ASTPSIFDIYDVSIARGRSLTRLDMEELNQVVVLSYDTAEKLFEGVNPVGKKLNLSGLTF
ECCCCEEEEEECHHHCCCCCCCCCHHHCCCEEEEEECCHHHHHHCCCCCCCCEECCCCCE
TVIGVLEEGEKSIIPTSVTNNTVFIPFSVFERIFDVHNRFILMARLKDKSLVDTGIKRVQ
EEEEEHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHH
QLLDRRHGMADNGMSKFRVSSWVSGLKEISIIKTVLIVLLSGVASITLLVAGIGLMNIML
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVTERTREIGLRKALGATNRDILIQFIIESIVLCIVGGILGVIVGYLGSEVALNIANKY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
INFSYSVPRWAVLLSLTFTTLVGLFFGIYPAYKAARLNPIEALRYE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA