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The map label for this gene is adhE [H]

Identifier: 220931059

GI number: 220931059

Start: 216770

End: 219433

Strand: Direct

Name: adhE [H]

Synonym: Hore_02110

Alternate gene names: 220931059

Gene position: 216770-219433 (Clockwise)

Preceding gene: 220931058

Following gene: 220931060

Centisome position: 8.41

GC content: 41.7

Gene sequence:

>2664_bases
ATGGCTAAAGCGGTATTAGAAAAAAGTGTTGATAAGGCTACAAAGGAAAAGAAAGAGATTAGAAAAGGTTTAAAGATTGA
AGATAGTATCAACAAACTGGTAGAAAGGGCAAATGAAGCTGCCAGGAAGTTTAAAGATTATGACCAGGAACAGGTTGACA
GGATTGTAAAAAAGATGGCTCTGGCCGCCAATGATAAACATATTGAACTTGCTAAAATGGCCCATCGGGAAACAGGAATG
GGGGTCTATGAAGATAAAATAACTAAAAATCTTTTTGCTTCTGAGTATGTTTATAACTATCTCAGGGATAAGAAAACAGC
TGGAATTTTAAATAAAAACATTGAAGAAAATTATATTGAGGTTGCAGAACCAATCGGGGTTGTAGCTGCTTTAACTCCTG
TTACCAATCCTACTTCTACTACTATTTTTAAGGCTTTAATATGTATGAAGACCAGGAATCCAGTTATTTTTAGTTTCCAT
CCCCGGGCTATGAAGTGTAGTATTGAAGCAGCCCGGATCTTGAAGGAAGCTGCTATTAAGGCCGGTGCTCCTGAGAATTG
CATTAGCTGGATTGAAGAACCATCTATTGAGGCTACCAACTATTTAATGAAACATCCTGAGGTGGATTTAATTCTGGCTA
CCGGTGGTTCTGGAATGGTAAAAGCAGCCTATTCCAGTGGCAAACCAGCTCTGGGGGTTGGACCCGGTAATGTTCCCTGC
TATATAGAAAAGACAGCCAATATAAAGCAGGCCGTATCTGACCTTATTTTGAGTAAAACCTTTGATAATGGTATGATCTG
TGCCTCTGAACAGGCTGTAGTCGTTGATAAAGAAATTGCTGCTGAGGTTAAAAAGTTCATGCAGGAAAATGGTTGTTATT
TTGTCAGTAAAAAGGAGTCAGAAAAACTGGCCAGAGTGGCAGTGGACCAGGAAAGGGGTGCCATGAATCCGGCTGTAGTC
GGTCAACCTGCCCGTAAAATTGCCAAGATGGCCGGCATTAAAGTGCCTGATGACACCAAAATCCTGGTAGCAGAACTTAA
GGGAGTTGGAGAGAATTACCCCCTGTCCCGGGAAAAATTAAGCCCGATTCTCGGCTGGTATGTTGTCAAAGACTATCGTG
AAGGAATAAAACGGTGTGAAGAGATAACAGAATTTGGAGGACTTGGACATTCTTCTGTGCTTCACAGTAATGATGAAAAA
GTAATTGATGAATTCAGTCGGAGATTGAGGACCGGTAGATTAATTATTAATTCACCTTCATCCCAGGGAGCAATAGGAGA
TATGTATAACTTTAATGTCCCTTCCCTGACCCTGGGTTGTGGTTCTATGGGTAAAAACTCAACAACCGATAATGTCAATG
TTGATAATTTAATTAATAAGAAGAGGGTAGCCATGAGAAAGGAAAGGATGAAATGGGTTAAAGTTCCTCCCAGGATATAT
TTTGAATATGGTTCCCTTCGCTATCTGTCAGGAGTTAGAGGTGAGAGGGCCTTTATAATTACTGATAAGACTATGTCCCA
GCTTGGTTTTATTGATAAGGTTGAAGAACATCTATCTGTAGCCGGTGTCCAGACCAGGGTATTTGACAGTGTTGAGCCTG
ATCCATCAGTAGAAACGGTATTAAATGGTTGCCAGGAGATGAATGAATTTAAACCTGATATCATCATTGCCCTGGGTGGG
GGTTCCCCGATGGATGCTGCTAAAGGTATGTGGCTATTCTATGAACACCCGGAAACCAGGTTTGAAGATCTGAAGATGAA
GTTTAATGATATTAGAAAAAGGGTTTATAAATTCCCCAGGCTGGGTAAAAAGGCTACTTTTATTGCAGTACCTACAACAT
CAGGAACCGGTTCTGAGGTAACCGCCTTTTCAGTAATAACTGATAAGAAACGTAATATTAAGTATCCACTGGCTGATTAT
GAACTTACCCCTGATATTGCTATAATTGATCCAGAACTGGTCCTGACAGTTCCCCAGTCAGTAACAGCAGATACAGGACT
GGATGTTTTGACCCATGCTATTGAGGCCTATGTTTCGGTTATGGCTTCTGATTACACTGATGCCCTGGCTGAAAAGGCTA
TCAAGCTGGTATTTGAATATCTCCCCCGGGCTTATAAGAATGGTAATGACCGGGAAGCAAGAAAGAAGATGCATAATGCT
TCCTGTATTGCCGGAATGGCCTTTACTAATGCATTCCTGGGGCTTAACCACAGTATGGCCCATATACTGGGAGGTAAGTT
TCATATCCCTCACGGCCGGGCTAATGCAATTTTATTGCCACATGTTATTAGATATAATGCCGGGAAACCAAGTAAGCTGG
CCAGCTTCCCCCAGTATGATTATCCTCGGGCAGGAGAAAGGTATGCTGAAATAGCCAGAATACTGGGACTTCCCGCTTCC
ACTACAGAAGAAGGGGTTGAAAGCCTGGTTAAAGCCATAACAGACCTGATGAGAGAATTAAATATCCCCCTTTCTCTGGA
AGAAGCCGGGGTAAATCACAACAAGTTCGAAAAAGAACTCGAAGATATGGCTGATATTGCCCATAATGACCAGTGTACTG
GAACTAACCCCAGAATGCCGCTGGTCAATGAAATCAAGGAGATCTATCGTCAGGCGTATAAAGGGGTCAGTATTAAAGAT
AAAAAGAAAGTCCGTAATGCTTAG

Upstream 100 bases:

>100_bases
TTATAGAAAACGTCCACATCAGTGAGAGTTTAATGACACTTTCTTATAAAGTAAAAGAGAAAGACAAATAAGATTACAAG
AATATAAGGAGGTTTTTAAA

Downstream 100 bases:

>100_bases
GTGTTAATCAGTAATAACATATAGGAAAATATGTTGGCATATATTGATAAGGATGTCAGCCCATATGGGTCTGGCATATT
TTTTTTCTAATAAAAATTAT

Product: bifunctional acetaldehyde-CoA/alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase; ADH; Acetaldehyde dehydrogenase [acetylating]; ACDH; Pyruvate-formate-lyase deactivase; PFL deactivase [H]

Number of amino acids: Translated: 887; Mature: 886

Protein sequence:

>887_residues
MAKAVLEKSVDKATKEKKEIRKGLKIEDSINKLVERANEAARKFKDYDQEQVDRIVKKMALAANDKHIELAKMAHRETGM
GVYEDKITKNLFASEYVYNYLRDKKTAGILNKNIEENYIEVAEPIGVVAALTPVTNPTSTTIFKALICMKTRNPVIFSFH
PRAMKCSIEAARILKEAAIKAGAPENCISWIEEPSIEATNYLMKHPEVDLILATGGSGMVKAAYSSGKPALGVGPGNVPC
YIEKTANIKQAVSDLILSKTFDNGMICASEQAVVVDKEIAAEVKKFMQENGCYFVSKKESEKLARVAVDQERGAMNPAVV
GQPARKIAKMAGIKVPDDTKILVAELKGVGENYPLSREKLSPILGWYVVKDYREGIKRCEEITEFGGLGHSSVLHSNDEK
VIDEFSRRLRTGRLIINSPSSQGAIGDMYNFNVPSLTLGCGSMGKNSTTDNVNVDNLINKKRVAMRKERMKWVKVPPRIY
FEYGSLRYLSGVRGERAFIITDKTMSQLGFIDKVEEHLSVAGVQTRVFDSVEPDPSVETVLNGCQEMNEFKPDIIIALGG
GSPMDAAKGMWLFYEHPETRFEDLKMKFNDIRKRVYKFPRLGKKATFIAVPTTSGTGSEVTAFSVITDKKRNIKYPLADY
ELTPDIAIIDPELVLTVPQSVTADTGLDVLTHAIEAYVSVMASDYTDALAEKAIKLVFEYLPRAYKNGNDREARKKMHNA
SCIAGMAFTNAFLGLNHSMAHILGGKFHIPHGRANAILLPHVIRYNAGKPSKLASFPQYDYPRAGERYAEIARILGLPAS
TTEEGVESLVKAITDLMRELNIPLSLEEAGVNHNKFEKELEDMADIAHNDQCTGTNPRMPLVNEIKEIYRQAYKGVSIKD
KKKVRNA

Sequences:

>Translated_887_residues
MAKAVLEKSVDKATKEKKEIRKGLKIEDSINKLVERANEAARKFKDYDQEQVDRIVKKMALAANDKHIELAKMAHRETGM
GVYEDKITKNLFASEYVYNYLRDKKTAGILNKNIEENYIEVAEPIGVVAALTPVTNPTSTTIFKALICMKTRNPVIFSFH
PRAMKCSIEAARILKEAAIKAGAPENCISWIEEPSIEATNYLMKHPEVDLILATGGSGMVKAAYSSGKPALGVGPGNVPC
YIEKTANIKQAVSDLILSKTFDNGMICASEQAVVVDKEIAAEVKKFMQENGCYFVSKKESEKLARVAVDQERGAMNPAVV
GQPARKIAKMAGIKVPDDTKILVAELKGVGENYPLSREKLSPILGWYVVKDYREGIKRCEEITEFGGLGHSSVLHSNDEK
VIDEFSRRLRTGRLIINSPSSQGAIGDMYNFNVPSLTLGCGSMGKNSTTDNVNVDNLINKKRVAMRKERMKWVKVPPRIY
FEYGSLRYLSGVRGERAFIITDKTMSQLGFIDKVEEHLSVAGVQTRVFDSVEPDPSVETVLNGCQEMNEFKPDIIIALGG
GSPMDAAKGMWLFYEHPETRFEDLKMKFNDIRKRVYKFPRLGKKATFIAVPTTSGTGSEVTAFSVITDKKRNIKYPLADY
ELTPDIAIIDPELVLTVPQSVTADTGLDVLTHAIEAYVSVMASDYTDALAEKAIKLVFEYLPRAYKNGNDREARKKMHNA
SCIAGMAFTNAFLGLNHSMAHILGGKFHIPHGRANAILLPHVIRYNAGKPSKLASFPQYDYPRAGERYAEIARILGLPAS
TTEEGVESLVKAITDLMRELNIPLSLEEAGVNHNKFEKELEDMADIAHNDQCTGTNPRMPLVNEIKEIYRQAYKGVSIKD
KKKVRNA
>Mature_886_residues
AKAVLEKSVDKATKEKKEIRKGLKIEDSINKLVERANEAARKFKDYDQEQVDRIVKKMALAANDKHIELAKMAHRETGMG
VYEDKITKNLFASEYVYNYLRDKKTAGILNKNIEENYIEVAEPIGVVAALTPVTNPTSTTIFKALICMKTRNPVIFSFHP
RAMKCSIEAARILKEAAIKAGAPENCISWIEEPSIEATNYLMKHPEVDLILATGGSGMVKAAYSSGKPALGVGPGNVPCY
IEKTANIKQAVSDLILSKTFDNGMICASEQAVVVDKEIAAEVKKFMQENGCYFVSKKESEKLARVAVDQERGAMNPAVVG
QPARKIAKMAGIKVPDDTKILVAELKGVGENYPLSREKLSPILGWYVVKDYREGIKRCEEITEFGGLGHSSVLHSNDEKV
IDEFSRRLRTGRLIINSPSSQGAIGDMYNFNVPSLTLGCGSMGKNSTTDNVNVDNLINKKRVAMRKERMKWVKVPPRIYF
EYGSLRYLSGVRGERAFIITDKTMSQLGFIDKVEEHLSVAGVQTRVFDSVEPDPSVETVLNGCQEMNEFKPDIIIALGGG
SPMDAAKGMWLFYEHPETRFEDLKMKFNDIRKRVYKFPRLGKKATFIAVPTTSGTGSEVTAFSVITDKKRNIKYPLADYE
LTPDIAIIDPELVLTVPQSVTADTGLDVLTHAIEAYVSVMASDYTDALAEKAIKLVFEYLPRAYKNGNDREARKKMHNAS
CIAGMAFTNAFLGLNHSMAHILGGKFHIPHGRANAILLPHVIRYNAGKPSKLASFPQYDYPRAGERYAEIARILGLPAST
TEEGVESLVKAITDLMRELNIPLSLEEAGVNHNKFEKELEDMADIAHNDQCTGTNPRMPLVNEIKEIYRQAYKGVSIKDK
KKVRNA

Specific function: This enzyme has three activities:ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the iron- containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=376, Percent_Identity=28.1914893617021, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1787493, Length=858, Percent_Identity=52.4475524475524, Blast_Score=885, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=384, Percent_Identity=38.0208333333333, Blast_Score=238, Evalue=2e-63,
Organism=Escherichia coli, GI1789163, Length=381, Percent_Identity=37.007874015748, Blast_Score=236, Evalue=5e-63,
Organism=Escherichia coli, GI87082107, Length=409, Percent_Identity=34.9633251833741, Blast_Score=221, Evalue=2e-58,
Organism=Escherichia coli, GI1788797, Length=379, Percent_Identity=30.3430079155673, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1789386, Length=405, Percent_Identity=24.1975308641975, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=379, Percent_Identity=24.802110817942, Blast_Score=115, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321181, Length=406, Percent_Identity=35.4679802955665, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24657991, Length=398, Percent_Identity=27.6381909547739, Blast_Score=103, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR012079 [H]

Pfam domain/function: PF00171 Aldedh; PF00465 Fe-ADH [H]

EC number: =1.1.1.1; =1.2.1.10 [H]

Molecular weight: Translated: 98486; Mature: 98354

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAVLEKSVDKATKEKKEIRKGLKIEDSINKLVERANEAARKFKDYDQEQVDRIVKKMA
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LAANDKHIELAKMAHRETGMGVYEDKITKNLFASEYVYNYLRDKKTAGILNKNIEENYIE
HHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VAEPIGVVAALTPVTNPTSTTIFKALICMKTRNPVIFSFHPRAMKCSIEAARILKEAAIK
HHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHEEHHHHHHHHHHHHHC
AGAPENCISWIEEPSIEATNYLMKHPEVDLILATGGSGMVKAAYSSGKPALGVGPGNVPC
CCCCHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCE
YIEKTANIKQAVSDLILSKTFDNGMICASEQAVVVDKEIAAEVKKFMQENGCYFVSKKES
EEECCCCHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCEEEECCHH
EKLARVAVDQERGAMNPAVVGQPARKIAKMAGIKVPDDTKILVAELKGVGENYPLSREKL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEHEEHHCCCCCCCCCHHHH
SPILGWYVVKDYREGIKRCEEITEFGGLGHSSVLHSNDEKVIDEFSRRLRTGRLIINSPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHCEEEEECCC
SQGAIGDMYNFNVPSLTLGCGSMGKNSTTDNVNVDNLINKKRVAMRKERMKWVKVPPRIY
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEE
FEYGSLRYLSGVRGERAFIITDKTMSQLGFIDKVEEHLSVAGVQTRVFDSVEPDPSVETV
EECCCCHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LNGCQEMNEFKPDIIIALGGGSPMDAAKGMWLFYEHPETRFEDLKMKFNDIRKRVYKFPR
HHHHHHHHHCCCCEEEEECCCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
LGKKATFIAVPTTSGTGSEVTAFSVITDKKRNIKYPLADYELTPDIAIIDPELVLTVPQS
CCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCC
VTADTGLDVLTHAIEAYVSVMASDYTDALAEKAIKLVFEYLPRAYKNGNDREARKKMHNA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCH
SCIAGMAFTNAFLGLNHSMAHILGGKFHIPHGRANAILLPHVIRYNAGKPSKLASFPQYD
HHHHHHHHHHHHHCCCHHHHHHCCCEEECCCCCCCEEECCHHHHCCCCCCHHHCCCCCCC
YPRAGERYAEIARILGLPASTTEEGVESLVKAITDLMRELNIPLSLEEAGVNHNKFEKEL
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHHHHH
EDMADIAHNDQCTGTNPRMPLVNEIKEIYRQAYKGVSIKDKKKVRNA
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure 
AKAVLEKSVDKATKEKKEIRKGLKIEDSINKLVERANEAARKFKDYDQEQVDRIVKKMA
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LAANDKHIELAKMAHRETGMGVYEDKITKNLFASEYVYNYLRDKKTAGILNKNIEENYIE
HHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VAEPIGVVAALTPVTNPTSTTIFKALICMKTRNPVIFSFHPRAMKCSIEAARILKEAAIK
HHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHEEHHHHHHHHHHHHHC
AGAPENCISWIEEPSIEATNYLMKHPEVDLILATGGSGMVKAAYSSGKPALGVGPGNVPC
CCCCHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCE
YIEKTANIKQAVSDLILSKTFDNGMICASEQAVVVDKEIAAEVKKFMQENGCYFVSKKES
EEECCCCHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCEEEECCHH
EKLARVAVDQERGAMNPAVVGQPARKIAKMAGIKVPDDTKILVAELKGVGENYPLSREKL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEHEEHHCCCCCCCCCHHHH
SPILGWYVVKDYREGIKRCEEITEFGGLGHSSVLHSNDEKVIDEFSRRLRTGRLIINSPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHCEEEEECCC
SQGAIGDMYNFNVPSLTLGCGSMGKNSTTDNVNVDNLINKKRVAMRKERMKWVKVPPRIY
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEE
FEYGSLRYLSGVRGERAFIITDKTMSQLGFIDKVEEHLSVAGVQTRVFDSVEPDPSVETV
EECCCCHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LNGCQEMNEFKPDIIIALGGGSPMDAAKGMWLFYEHPETRFEDLKMKFNDIRKRVYKFPR
HHHHHHHHHCCCCEEEEECCCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
LGKKATFIAVPTTSGTGSEVTAFSVITDKKRNIKYPLADYELTPDIAIIDPELVLTVPQS
CCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCC
VTADTGLDVLTHAIEAYVSVMASDYTDALAEKAIKLVFEYLPRAYKNGNDREARKKMHNA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCH
SCIAGMAFTNAFLGLNHSMAHILGGKFHIPHGRANAILLPHVIRYNAGKPSKLASFPQYD
HHHHHHHHHHHHHCCCHHHHHHCCCEEECCCCCCCEEECCHHHHCCCCCCHHHCCCCCCC
YPRAGERYAEIARILGLPASTTEEGVESLVKAITDLMRELNIPLSLEEAGVNHNKFEKEL
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHHHHH
EDMADIAHNDQCTGTNPRMPLVNEIKEIYRQAYKGVSIKDKKKVRNA
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]