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The map label for this gene is yacO [H]

Identifier: 220930947

GI number: 220930947

Start: 117621

End: 118355

Strand: Direct

Name: yacO [H]

Synonym: Hore_00990

Alternate gene names: 220930947

Gene position: 117621-118355 (Clockwise)

Preceding gene: 220930946

Following gene: 220930948

Centisome position: 4.56

GC content: 44.08

Gene sequence:

>735_bases
ATGGCCCAGATTGAAGGCCGCAATCCAGTTATTGAAGCTATTAAAAGCGGGAGAACTATTAAAAAAATATTTATACAGGA
AGGGGTCAGGGGTAAGAAAGTAGACAGGATAATAAAAGAAGCCAGCAGGTTTAATATTCCACTTCAAAAAGCCAAAAAGG
ATTTTCTGGATAAAAAGGCCAGGTCCCATTCCCATCAGGGTATTATAGCCATGGCTGATGATATTAAATATGTATCTCCC
CGTGAAATGGTTGAAATTGCCAGGGAAAAAGGAGAAGATCCCTTTATTATAATACTTGATCAGGTACAGGATCCCCACAA
TCTCGGTGCTATAATTAGAACAGCTTATGCAGCAGGAGCCCATGGGCTGATTTATCCCCGGAAAAGGTCAGCCGACATTA
CCCCGGTTGTGACCAAAGCCTCGGCCGGAGCTGTTAATCACCTGCCTCTGGCTAAAGTCTCCAATATAAACTATACCATT
GCTGACTTGAAAGATATGGGTCTATGGATAACGGGGACCGATGTCAGGGGGACCAGACCTTATTATTCTGCAGATTATAA
AGGTCCAGTCGGACTTGTAATTGGAAACGAAGGTAAGGGGATGCGTCGTCTGGTAAAAGAAAATTGTGACTTTGTGGTTA
ATATCCCCATGAGTGGTGAACTGGGGTCCCTCAACGCTTCAGTGGCAGCAGGGGTAGTTATTTTTGAGGTTGTCCGACAA
CGGCGCTCAACTTAA

Upstream 100 bases:

>100_bases
GCAGGACCTACCTGTGAGGTAGAAGGTTACTGTCCTGAAGGGGAATTTTCCTGTGGCCGTATTGATAATATAAAAACATC
ATAAGAGGTGATATAATATT

Downstream 100 bases:

>100_bases
TACTGCTTGACTATGTTCTATTAAATAAGTATAATAGAGATGTATAAGGGAGGGGATCCTGGTTGAAGGGAAATGCACAG
GAAAAATATGATTATGAAGA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAQIEGRNPVIEAIKSGRTIKKIFIQEGVRGKKVDRIIKEASRFNIPLQKAKKDFLDKKARSHSHQGIIAMADDIKYVSP
REMVEIAREKGEDPFIIILDQVQDPHNLGAIIRTAYAAGAHGLIYPRKRSADITPVVTKASAGAVNHLPLAKVSNINYTI
ADLKDMGLWITGTDVRGTRPYYSADYKGPVGLVIGNEGKGMRRLVKENCDFVVNIPMSGELGSLNASVAAGVVIFEVVRQ
RRST

Sequences:

>Translated_244_residues
MAQIEGRNPVIEAIKSGRTIKKIFIQEGVRGKKVDRIIKEASRFNIPLQKAKKDFLDKKARSHSHQGIIAMADDIKYVSP
REMVEIAREKGEDPFIIILDQVQDPHNLGAIIRTAYAAGAHGLIYPRKRSADITPVVTKASAGAVNHLPLAKVSNINYTI
ADLKDMGLWITGTDVRGTRPYYSADYKGPVGLVIGNEGKGMRRLVKENCDFVVNIPMSGELGSLNASVAAGVVIFEVVRQ
RRST
>Mature_243_residues
AQIEGRNPVIEAIKSGRTIKKIFIQEGVRGKKVDRIIKEASRFNIPLQKAKKDFLDKKARSHSHQGIIAMADDIKYVSPR
EMVEIAREKGEDPFIIILDQVQDPHNLGAIIRTAYAAGAHGLIYPRKRSADITPVVTKASAGAVNHLPLAKVSNINYTIA
DLKDMGLWITGTDVRGTRPYYSADYKGPVGLVIGNEGKGMRRLVKENCDFVVNIPMSGELGSLNASVAAGVVIFEVVRQR
RST

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=258, Percent_Identity=28.2945736434109, Blast_Score=114, Evalue=6e-26,
Organism=Escherichia coli, GI1790623, Length=222, Percent_Identity=38.2882882882883, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790083, Length=152, Percent_Identity=30.9210526315789, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788935, Length=228, Percent_Identity=24.1228070175439, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555908, Length=260, Percent_Identity=29.6153846153846, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=36.969696969697, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26817; Mature: 26686

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQIEGRNPVIEAIKSGRTIKKIFIQEGVRGKKVDRIIKEASRFNIPLQKAKKDFLDKKA
CCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RSHSHQGIIAMADDIKYVSPREMVEIAREKGEDPFIIILDQVQDPHNLGAIIRTAYAAGA
HCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC
HGLIYPRKRSADITPVVTKASAGAVNHLPLAKVSNINYTIADLKDMGLWITGTDVRGTRP
CCEECCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCEEEEEHHHCCEEEECCCCCCCCC
YYSADYKGPVGLVIGNEGKGMRRLVKENCDFVVNIPMSGELGSLNASVAAGVVIFEVVRQ
CCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
RRST
HHCC
>Mature Secondary Structure 
AQIEGRNPVIEAIKSGRTIKKIFIQEGVRGKKVDRIIKEASRFNIPLQKAKKDFLDKKA
CCCCCCCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RSHSHQGIIAMADDIKYVSPREMVEIAREKGEDPFIIILDQVQDPHNLGAIIRTAYAAGA
HCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC
HGLIYPRKRSADITPVVTKASAGAVNHLPLAKVSNINYTIADLKDMGLWITGTDVRGTRP
CCEECCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCEEEEEHHHCCEEEECCCCCCCCC
YYSADYKGPVGLVIGNEGKGMRRLVKENCDFVVNIPMSGELGSLNASVAAGVVIFEVVRQ
CCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
RRST
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]