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The map label for this gene is fixC [H]

Identifier: 220930864

GI number: 220930864

Start: 15680

End: 16846

Strand: Reverse

Name: fixC [H]

Synonym: Hore_00140

Alternate gene names: 220930864

Gene position: 16846-15680 (Counterclockwise)

Preceding gene: 220930871

Following gene: 220930863

Centisome position: 0.65

GC content: 42.5

Gene sequence:

>1167_bases
GTGATTTATCGGGAGGCAACAGCCCAGATCGTACCTAATTTCTGGGAAGAAGCTCCAGTAGAACGGGCTATCGTTACCGA
TACTTTATGGTTTATGGACCAGACCTCGGCTGTCCAGGTAGGTTTTACTGGCCTTAACTATGCTAAACCACCCTATAATA
AATTTTCGGTCATCAGATCACGTTTTGATCACTGGCTTGCCAAAAAAGCCGAAGAAGCAGGGGCTCATTTAATGACATCC
TGTCTGGTTAAAGACCTTATCTTTGAAAAAGAGGGACTGACAGGGAAAAAGGTTGCCGGGGTAGTCCTTGATGATGGTAG
TAAACTTTATAGTGATGCAGTAATTCTGGCTGAAGGAGCCATGGCTGATCTCGCTGCTAAGGCAGGACTCAGGCGTGAAA
TCTCTGCTGACAGCCTTAAAATATATGTAAAGGAAATTCTGGCCCTCCCCCGGGAAATAATAGAAGCCCGTTTTAACCTG
GAGAAAGACGAAGGGGTGATTATAGGCATGGTTGGTTTCCCCACTTCAGGGGCTGTGGGAAAAGGTGGTATCTGGACCAA
CCGTGATAGTATTTCACTGGTGGTGGGAGGATATCTAAACCAGATTGTCAATAAAGGTTTAAACCTCTATCAACTCCTCA
ACCGGCTGAAAAAACATCCCATGATCAGGAGACTTATTGAAGGAGCAAAAACAGTCCAGTATATGTCCCATCTTATCCCC
AAAGGAGGTTATAAAAGTCTACCTCAGTTTTATGATAATGGTATCCTGATAACCGGAGATGCCGGTATGCTGGTCAGTGG
ACGCCACGGAACCGATATTGCCATGCTGTCCGGTAAATATGCTGCTGAAACTGCTTTACAGGCTAAAGCCAGAGGGGATT
TTTCTAAAAAGACCCTCTCCTCATATGAAAATAAACTTAAGAATACTTTTTTTATGCGGGCCATAGAAAGTAATAAAGAA
GCCCGGGATTATTACCGGGAATACCCTGATTCTGACTTTGTTTTCAGTAAAACCCTGAACGAAGTGGCCTATGAATTTTT
CAAAGAAGGCTTAAAAACCCAGGATGAAAAGCTGAATGAAATAATAGAAGAAGTTAAAGAAATTCAATCACTCCAAAAAA
ATATCAGAGATATATATTCTGGATTACAGCACTGGAGGGTATTTTAA

Upstream 100 bases:

>100_bases
CTGCCGGTTCTTCGGCAGCCCTGGTCGGGGCCCGGGGAAACCTTTCTGTAGCCCTCCTTGAAAGGGGACAATACCCCGGA
AGTAAAAATATGTTTGGTGG

Downstream 100 bases:

>100_bases
AATTGACTAGTTTTTTAAAAAATAATGAGAATCCCCTTAAATATGTAAATATAATCCCTGCAGGTAAATCTCATATCCAT
ATAAGGAATAAAAAGGTCTG

Product: Electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIYREATAQIVPNFWEEAPVERAIVTDTLWFMDQTSAVQVGFTGLNYAKPPYNKFSVIRSRFDHWLAKKAEEAGAHLMTS
CLVKDLIFEKEGLTGKKVAGVVLDDGSKLYSDAVILAEGAMADLAAKAGLRREISADSLKIYVKEILALPREIIEARFNL
EKDEGVIIGMVGFPTSGAVGKGGIWTNRDSISLVVGGYLNQIVNKGLNLYQLLNRLKKHPMIRRLIEGAKTVQYMSHLIP
KGGYKSLPQFYDNGILITGDAGMLVSGRHGTDIAMLSGKYAAETALQAKARGDFSKKTLSSYENKLKNTFFMRAIESNKE
ARDYYREYPDSDFVFSKTLNEVAYEFFKEGLKTQDEKLNEIIEEVKEIQSLQKNIRDIYSGLQHWRVF

Sequences:

>Translated_388_residues
MIYREATAQIVPNFWEEAPVERAIVTDTLWFMDQTSAVQVGFTGLNYAKPPYNKFSVIRSRFDHWLAKKAEEAGAHLMTS
CLVKDLIFEKEGLTGKKVAGVVLDDGSKLYSDAVILAEGAMADLAAKAGLRREISADSLKIYVKEILALPREIIEARFNL
EKDEGVIIGMVGFPTSGAVGKGGIWTNRDSISLVVGGYLNQIVNKGLNLYQLLNRLKKHPMIRRLIEGAKTVQYMSHLIP
KGGYKSLPQFYDNGILITGDAGMLVSGRHGTDIAMLSGKYAAETALQAKARGDFSKKTLSSYENKLKNTFFMRAIESNKE
ARDYYREYPDSDFVFSKTLNEVAYEFFKEGLKTQDEKLNEIIEEVKEIQSLQKNIRDIYSGLQHWRVF
>Mature_388_residues
MIYREATAQIVPNFWEEAPVERAIVTDTLWFMDQTSAVQVGFTGLNYAKPPYNKFSVIRSRFDHWLAKKAEEAGAHLMTS
CLVKDLIFEKEGLTGKKVAGVVLDDGSKLYSDAVILAEGAMADLAAKAGLRREISADSLKIYVKEILALPREIIEARFNL
EKDEGVIIGMVGFPTSGAVGKGGIWTNRDSISLVVGGYLNQIVNKGLNLYQLLNRLKKHPMIRRLIEGAKTVQYMSHLIP
KGGYKSLPQFYDNGILITGDAGMLVSGRHGTDIAMLSGKYAAETALQAKARGDFSKKTLSSYENKLKNTFFMRAIESNKE
ARDYYREYPDSDFVFSKTLNEVAYEFFKEGLKTQDEKLNEIIEEVKEIQSLQKNIRDIYSGLQHWRVF

Specific function: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from fixA/fixB and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=354, Percent_Identity=24.5762711864407, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786227, Length=311, Percent_Identity=36.0128617363344, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787991, Length=332, Percent_Identity=33.433734939759, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI87082155, Length=340, Percent_Identity=29.4117647058824, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25144720, Length=354, Percent_Identity=22.5988700564972, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324932, Length=250, Percent_Identity=27.6, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652256, Length=350, Percent_Identity=24.2857142857143, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.5.5.-

Molecular weight: Translated: 43612; Mature: 43612

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYREATAQIVPNFWEEAPVERAIVTDTLWFMDQTSAVQVGFTGLNYAKPPYNKFSVIRS
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHH
RFDHWLAKKAEEAGAHLMTSCLVKDLIFEKEGLTGKKVAGVVLDDGSKLYSDAVILAEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHCHHEEECCH
MADLAAKAGLRREISADSLKIYVKEILALPREIIEARFNLEKDEGVIIGMVGFPTSGAVG
HHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
KGGIWTNRDSISLVVGGYLNQIVNKGLNLYQLLNRLKKHPMIRRLIEGAKTVQYMSHLIP
CCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
KGGYKSLPQFYDNGILITGDAGMLVSGRHGTDIAMLSGKYAAETALQAKARGDFSKKTLS
CCCCHHHHHHHCCCEEEECCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHH
SYENKLKNTFFMRAIESNKEARDYYREYPDSDFVFSKTLNEVAYEFFKEGLKTQDEKLNE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IIEEVKEIQSLQKNIRDIYSGLQHWRVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYREATAQIVPNFWEEAPVERAIVTDTLWFMDQTSAVQVGFTGLNYAKPPYNKFSVIRS
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHH
RFDHWLAKKAEEAGAHLMTSCLVKDLIFEKEGLTGKKVAGVVLDDGSKLYSDAVILAEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHCHHEEECCH
MADLAAKAGLRREISADSLKIYVKEILALPREIIEARFNLEKDEGVIIGMVGFPTSGAVG
HHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
KGGIWTNRDSISLVVGGYLNQIVNKGLNLYQLLNRLKKHPMIRRLIEGAKTVQYMSHLIP
CCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
KGGYKSLPQFYDNGILITGDAGMLVSGRHGTDIAMLSGKYAAETALQAKARGDFSKKTLS
CCCCHHHHHHHCCCEEEECCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHH
SYENKLKNTFFMRAIESNKEARDYYREYPDSDFVFSKTLNEVAYEFFKEGLKTQDEKLNE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IIEEVKEIQSLQKNIRDIYSGLQHWRVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1850088 [H]