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The map label for this gene is pdxA [H]

Identifier: 220919570

GI number: 220919570

Start: 5005755

End: 5006771

Strand: Direct

Name: pdxA [H]

Synonym: A2cp1_4491

Alternate gene names: 220919570

Gene position: 5005755-5006771 (Clockwise)

Preceding gene: 220919569

Following gene: 220919586

Centisome position: 99.53

GC content: 79.65

Gene sequence:

>1017_bases
GTGAGCCCCGCGGCCCGCCCGCGCGCCGGCCGCCCCCGCATCGCCATCTCGCTGGGCGATCCCTCCGGCGTCGGACCGGA
GGTGACCGCCGGCGCGCTGCGCGCGCTGCGCGGCGAGCTCGTCCCGCTGGTGTTCGGCGACCGCCGGGTGCTCTCCCGCG
CGCTCGGCGGCCTGGGCCTGCCGGTGGTCGAGCCCGGCGCGCCGCTGCCGCCCGGCGGCGCGCTCGTCGCCACCACCGCG
CTCCCCGCCGCCCAGCTCCGGCCCGGCCGCCCCGCGCCGGAGGCGGGCGCGGCCCAGCTCGCCTACGTGGCGGCCGCGTT
CCGCGCGGTGCGCGAGGGCGCGGCGGCGGCGCTCTGCACCGCGCCGGTGTCGAAGGCGCAGGTGGCGCGGGCGCTGCCCG
GGTTCGTGGGGCACACGGAGTGGCTGGAGGCCGCCTGCGGCGCGCGCCGCTCGGTGATGATGCTGGCCGGCGACCGGCTC
CGCATCGCGCTCGTCACGAACCACGTGGCCTTCTCGCGGCTGCGGCGCGCGCTCACCGTCCCCCGCATCGTCGACACGCT
CGCCATCACCCACCGCGCGCTCCGCGAGGACCTGGGCATCGCCCGGCCGCGCCTCGCGCTCGCCGCGCTCAACCCGCACG
CCGGCGAGGAGGGCGCCTTCGGCGACGAGGAGTCGCGGCTGCTCGCGCCCGCGCTCGAGGCCGCCCGCGCCGCGGGCGCG
CCCGCCGTCGGCCCGTTCCCGGCGGACTCCGTGTTCTTCCGCGCCGCGCTGGGCGAGTTCGACGCGGTGGTCGCGCTCTA
CCACGACCAGGGGCTCATCCCGGTGAAGCTGCTCGACGCGGTGGGCGGGGATCCGGCGGTGAACGTGACGCTGGGGCTGC
CCATCGTCCGCACCAGCCCGGACCACGGCGTCGCCTACGACATCGCGGGCAAGGGCAAGGCGAGCGCCGCCTCGATGATC
GCGGCGCTGCGGCTGGCCGTGCGGATCGCGAACGTCCGCGCGCGGGCGGCGCGGTAG

Upstream 100 bases:

>100_bases
AGCGGCTCGGCGAGGAGCAGGCCGAGAACTACCGGCAGCAGTACGTGGCCGAGCTCCGGCGCGACGCGCTCATCGACGTG
AAGCTGCCCGAGCTGCGGCC

Downstream 100 bases:

>100_bases
CGAGCAGAGCGTTGCGCGGCGAAGCCGCGCCCGCGGGGACCTCGCGCGTGCCCGCGCAGGCGGGCGCGCGAGGTCACGGG
CCCGCGCAGCAGGGTGGGGC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSPAARPRAGRPRIAISLGDPSGVGPEVTAGALRALRGELVPLVFGDRRVLSRALGGLGLPVVEPGAPLPPGGALVATTA
LPAAQLRPGRPAPEAGAAQLAYVAAAFRAVREGAAAALCTAPVSKAQVARALPGFVGHTEWLEAACGARRSVMMLAGDRL
RIALVTNHVAFSRLRRALTVPRIVDTLAITHRALREDLGIARPRLALAALNPHAGEEGAFGDEESRLLAPALEAARAAGA
PAVGPFPADSVFFRAALGEFDAVVALYHDQGLIPVKLLDAVGGDPAVNVTLGLPIVRTSPDHGVAYDIAGKGKASAASMI
AALRLAVRIANVRARAAR

Sequences:

>Translated_338_residues
MSPAARPRAGRPRIAISLGDPSGVGPEVTAGALRALRGELVPLVFGDRRVLSRALGGLGLPVVEPGAPLPPGGALVATTA
LPAAQLRPGRPAPEAGAAQLAYVAAAFRAVREGAAAALCTAPVSKAQVARALPGFVGHTEWLEAACGARRSVMMLAGDRL
RIALVTNHVAFSRLRRALTVPRIVDTLAITHRALREDLGIARPRLALAALNPHAGEEGAFGDEESRLLAPALEAARAAGA
PAVGPFPADSVFFRAALGEFDAVVALYHDQGLIPVKLLDAVGGDPAVNVTLGLPIVRTSPDHGVAYDIAGKGKASAASMI
AALRLAVRIANVRARAAR
>Mature_337_residues
SPAARPRAGRPRIAISLGDPSGVGPEVTAGALRALRGELVPLVFGDRRVLSRALGGLGLPVVEPGAPLPPGGALVATTAL
PAAQLRPGRPAPEAGAAQLAYVAAAFRAVREGAAAALCTAPVSKAQVARALPGFVGHTEWLEAACGARRSVMMLAGDRLR
IALVTNHVAFSRLRRALTVPRIVDTLAITHRALREDLGIARPRLALAALNPHAGEEGAFGDEESRLLAPALEAARAAGAP
AVGPFPADSVFFRAALGEFDAVVALYHDQGLIPVKLLDAVGGDPAVNVTLGLPIVRTSPDHGVAYDIAGKGKASAASMIA
ALRLAVRIANVRARAAR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=325, Percent_Identity=41.8461538461538, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34575; Mature: 34443

Theoretical pI: Translated: 11.45; Mature: 11.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAARPRAGRPRIAISLGDPSGVGPEVTAGALRALRGELVPLVFGDRRVLSRALGGLGL
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCC
PVVEPGAPLPPGGALVATTALPAAQLRPGRPAPEAGAAQLAYVAAAFRAVREGAAAALCT
CCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHH
APVSKAQVARALPGFVGHTEWLEAACGARRSVMMLAGDRLRIALVTNHVAFSRLRRALTV
CCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHH
PRIVDTLAITHRALREDLGIARPRLALAALNPHAGEEGAFGDEESRLLAPALEAARAAGA
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
PAVGPFPADSVFFRAALGEFDAVVALYHDQGLIPVKLLDAVGGDPAVNVTLGLPIVRTSP
CCCCCCCCHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCEEEEECC
DHGVAYDIAGKGKASAASMIAALRLAVRIANVRARAAR
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPAARPRAGRPRIAISLGDPSGVGPEVTAGALRALRGELVPLVFGDRRVLSRALGGLGL
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCC
PVVEPGAPLPPGGALVATTALPAAQLRPGRPAPEAGAAQLAYVAAAFRAVREGAAAALCT
CCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHH
APVSKAQVARALPGFVGHTEWLEAACGARRSVMMLAGDRLRIALVTNHVAFSRLRRALTV
CCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHH
PRIVDTLAITHRALREDLGIARPRLALAALNPHAGEEGAFGDEESRLLAPALEAARAAGA
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
PAVGPFPADSVFFRAALGEFDAVVALYHDQGLIPVKLLDAVGGDPAVNVTLGLPIVRTSP
CCCCCCCCHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCEEEEECC
DHGVAYDIAGKGKASAASMIAALRLAVRIANVRARAAR
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA