Click here to switch to the map view.

The map label for this gene is surA [H]

Identifier: 220919569

GI number: 220919569

Start: 5004742

End: 5005758

Strand: Direct

Name: surA [H]

Synonym: A2cp1_4490

Alternate gene names: 220919569

Gene position: 5004742-5005758 (Clockwise)

Preceding gene: 220919568

Following gene: 220919570

Centisome position: 99.51

GC content: 73.06

Gene sequence:

>1017_bases
TTGAACCTCTCCCTCGCGCTCCTCGCCGTCACCCTCTCGAACGCCGCGCCCGCCGCCCCGGCCGCGACGCCGCCTCCGGC
TGCCGCGGCCCAGCCGCGCCGCGTGCTCGACCGCGTGGCGGCCATCGTCAACGGCGACGTGGTGACGCTGCAGGAGCTGG
AGCAGCGCGCCGCCGCGCTCGGGCTGGCCGCCGCCGACGCGCTCCCCGCCGGCCCGGCGCGCGACAAGGCCCGCGCCGAC
GCGCTCCGGCGCGCGTTCGACCAGGTGGTCTCCGACAAGCTCTTCGCCGAGAAGGCGAAGGAGCTGGAGATCGAGGTCAC
CGAGAAGCAGGTGGACGACGCCATCGAGGGCGTGAAGAAGCAGAACGGCTTCACCGACGCCCAGCTCGAGTCCGCCCTCG
CCTCCGAGGGCTACTCCATGACCGACTACCGGGCCCGCATCCGGCGCGAGCTGCAGAACTTCTCGCTGCTCCAGTACAAG
GTGGCGGGCAAGATCAAGACCTCCGAGGAGGACCTGCGGAACTACTACCAGTCCCACCCCCAGGAGTTCGACGGCGAGGA
CGAGGTGCGGGTCCGACACATCTTCATCCCGTTCGCCGAGGGCGGCGGTGCGCAGGCCGAGGCGCAGGCGCGCGCCGAGG
GTCGGCGGGTGCTGCAGCGGCTGAAGACCGGCGAGGACTTCGGCGCGGTCGCGAAGGCCGTCTCGCGCGGCCCGTCCGCC
GAGGAGGGCGGCGAGCTGGGCTGGCTGAAGCGCGGCACCATCCACCGGACGCTCGAGGACGCCGCGTTCGCGCTGAAGAC
CGGCGAGATGTCCGGGCTGGTGGAGGCGGGCCCCGGCGTGCACATCCTCAAGGTCGAGGAGCGGCGGCGCGGCGGCGGCA
AGAGCTTCGAGCAGGCGCGCGACGAGATCCGGCAGCGGCTCGGCGAGGAGCAGGCCGAGAACTACCGGCAGCAGTACGTG
GCCGAGCTCCGGCGCGACGCGCTCATCGACGTGAAGCTGCCCGAGCTGCGGCCGTGA

Upstream 100 bases:

>100_bases
GCCGCGAGAAGCGGGCCGGGGCGCAGGCGGAGTACCTCGAGGCCCTCCGCAAGCGCGCCCAGATCGACATCGACGAGAAG
GCCCTCGCCGCGGTGACCCC

Downstream 100 bases:

>100_bases
GCCCCGCGGCCCGCCCGCGCGCCGGCCGCCCCCGCATCGCCATCTCGCTGGGCGATCCCTCCGGCGTCGGACCGGAGGTG
ACCGCCGGCGCGCTGCGCGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNLSLALLAVTLSNAAPAAPAATPPPAAAAQPRRVLDRVAAIVNGDVVTLQELEQRAAALGLAAADALPAGPARDKARAD
ALRRAFDQVVSDKLFAEKAKELEIEVTEKQVDDAIEGVKKQNGFTDAQLESALASEGYSMTDYRARIRRELQNFSLLQYK
VAGKIKTSEEDLRNYYQSHPQEFDGEDEVRVRHIFIPFAEGGGAQAEAQARAEGRRVLQRLKTGEDFGAVAKAVSRGPSA
EEGGELGWLKRGTIHRTLEDAAFALKTGEMSGLVEAGPGVHILKVEERRRGGGKSFEQARDEIRQRLGEEQAENYRQQYV
AELRRDALIDVKLPELRP

Sequences:

>Translated_338_residues
MNLSLALLAVTLSNAAPAAPAATPPPAAAAQPRRVLDRVAAIVNGDVVTLQELEQRAAALGLAAADALPAGPARDKARAD
ALRRAFDQVVSDKLFAEKAKELEIEVTEKQVDDAIEGVKKQNGFTDAQLESALASEGYSMTDYRARIRRELQNFSLLQYK
VAGKIKTSEEDLRNYYQSHPQEFDGEDEVRVRHIFIPFAEGGGAQAEAQARAEGRRVLQRLKTGEDFGAVAKAVSRGPSA
EEGGELGWLKRGTIHRTLEDAAFALKTGEMSGLVEAGPGVHILKVEERRRGGGKSFEQARDEIRQRLGEEQAENYRQQYV
AELRRDALIDVKLPELRP
>Mature_338_residues
MNLSLALLAVTLSNAAPAAPAATPPPAAAAQPRRVLDRVAAIVNGDVVTLQELEQRAAALGLAAADALPAGPARDKARAD
ALRRAFDQVVSDKLFAEKAKELEIEVTEKQVDDAIEGVKKQNGFTDAQLESALASEGYSMTDYRARIRRELQNFSLLQYK
VAGKIKTSEEDLRNYYQSHPQEFDGEDEVRVRHIFIPFAEGGGAQAEAQARAEGRRVLQRLKTGEDFGAVAKAVSRGPSA
EEGGELGWLKRGTIHRTLEDAAFALKTGEMSGLVEAGPGVHILKVEERRRGGGKSFEQARDEIRQRLGEEQAENYRQQYV
AELRRDALIDVKLPELRP

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=275, Percent_Identity=26.5454545454545, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786645, Length=147, Percent_Identity=29.9319727891156, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322478, Length=131, Percent_Identity=34.3511450381679, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36948; Mature: 36948

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSLALLAVTLSNAAPAAPAATPPPAAAAQPRRVLDRVAAIVNGDVVTLQELEQRAAAL
CCCHHEEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
GLAAADALPAGPARDKARADALRRAFDQVVSDKLFAEKAKELEIEVTEKQVDDAIEGVKK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHH
QNGFTDAQLESALASEGYSMTDYRARIRRELQNFSLLQYKVAGKIKTSEEDLRNYYQSHP
HCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEHHCCCCCCCHHHHHHHHHCCC
QEFDGEDEVRVRHIFIPFAEGGGAQAEAQARAEGRRVLQRLKTGEDFGAVAKAVSRGPSA
CCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
EEGGELGWLKRGTIHRTLEDAAFALKTGEMSGLVEAGPGVHILKVEERRRGGGKSFEQAR
CCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEHHHHCCCCCCHHHHH
DEIRQRLGEEQAENYRQQYVAELRRDALIDVKLPELRP
HHHHHHHCHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
>Mature Secondary Structure
MNLSLALLAVTLSNAAPAAPAATPPPAAAAQPRRVLDRVAAIVNGDVVTLQELEQRAAAL
CCCHHEEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
GLAAADALPAGPARDKARADALRRAFDQVVSDKLFAEKAKELEIEVTEKQVDDAIEGVKK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHH
QNGFTDAQLESALASEGYSMTDYRARIRRELQNFSLLQYKVAGKIKTSEEDLRNYYQSHP
HCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEHHCCCCCCCHHHHHHHHHCCC
QEFDGEDEVRVRHIFIPFAEGGGAQAEAQARAEGRRVLQRLKTGEDFGAVAKAVSRGPSA
CCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
EEGGELGWLKRGTIHRTLEDAAFALKTGEMSGLVEAGPGVHILKVEERRRGGGKSFEQAR
CCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEHHHHCCCCCCHHHHH
DEIRQRLGEEQAENYRQQYVAELRRDALIDVKLPELRP
HHHHHHHCHHHHHHHHHHHHHHHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA