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The map label for this gene is prsA [H]

Identifier: 220919568

GI number: 220919568

Start: 5003792

End: 5004745

Strand: Direct

Name: prsA [H]

Synonym: A2cp1_4489

Alternate gene names: 220919568

Gene position: 5003792-5004745 (Clockwise)

Preceding gene: 220919567

Following gene: 220919569

Centisome position: 99.49

GC content: 74.42

Gene sequence:

>954_bases
GTGCGCCCGGCCCTCGCGCCCATCCTGATCGCGACCGCGCTCGCCGCCGGCTGCGGCCGCTGCGGCGGCGCGCGCTCCGG
CGAGCGCCCCGCGCCCGGCGCGGTGGCGGTCGTGAACGGGGAGCCCATCGCCCCCGACGCGGTCGCGCGCGAGCTGCGCG
ACGCGCAGGCGGGCGCGGAGGGCCAGGGCCAGGCCACTGGCGACGTGCTGCGGCGGCGCGTGCTCGACGACCTCGTCGAT
CGCGCGCTGCTCCTGCAGCAGGCGCGTGCCCGCTCGATCGTCGTCGGCCAGGACCAGGTCGAGCGGGCCTTCCTCCGCCT
CCGGGCGGAGTACCCCGGCACCCACTTCGACGACCTGCTCGCGCAGGAGCGGCTCAGCCAGGCCGAGCTGAAGGCCCGCC
TCAAGGACCAGCTCACGGTGGAGCGCCTGTTCGAGCAGGAGGTGTTCCCGCAGGTCCAGGTGGTGGACGCCGAGGTCGAG
CGTTACTACGCGGAGCACGGCGCCGAGTTCCAGGAGCCGGAGCGGGTGCACGTGCTCCAGATCGTCGTCGCGAGCCGCGA
GGAGGCCGCCCAGGTGCGCGAGAAGCTCCGCCGCAACCCGCAGACGTTCGCCGAGGTGGCGCGCCGGTCCTCCATCGCCC
CCGAGGGCAAGAGCGGCGGCGACCTCGGCCTCATCGGGCGCGGCGCCGGGTTCCCGGAGGTGTTCGACACCTGCTTCTCG
CTGCCGGTGAACGTGATCTCCGACGTCACCCCGTCCCCGTACGGCTTCCACCTGTTCAAGGTGGTGGAGAAGAAGCCGGC
GCAACGGCGCACGCTGGAGCAGGCGCGCGCCGAGATCGCCGAGAAGCTCGGCCGCGAGAAGCGGGCCGGGGCGCAGGCGG
AGTACCTCGAGGCCCTCCGCAAGCGCGCCCAGATCGACATCGACGAGAAGGCCCTCGCCGCGGTGACCCCTTGA

Upstream 100 bases:

>100_bases
GGCGGCCACGGCCCCATGGGCGCCGGCCCCCGCCCCATGGGCGCGCCCGCGCCCGCGCCGGCCGCCGCGCCGGCCCCGGC
CCCCGCCCCGGCGAAGTGAC

Downstream 100 bases:

>100_bases
ACCTCTCCCTCGCGCTCCTCGCCGTCACCCTCTCGAACGCCGCGCCCGCCGCCCCGGCCGCGACGCCGCCTCCGGCTGCC
GCGGCCCAGCCGCGCCGCGT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MRPALAPILIATALAAGCGRCGGARSGERPAPGAVAVVNGEPIAPDAVARELRDAQAGAEGQGQATGDVLRRRVLDDLVD
RALLLQQARARSIVVGQDQVERAFLRLRAEYPGTHFDDLLAQERLSQAELKARLKDQLTVERLFEQEVFPQVQVVDAEVE
RYYAEHGAEFQEPERVHVLQIVVASREEAAQVREKLRRNPQTFAEVARRSSIAPEGKSGGDLGLIGRGAGFPEVFDTCFS
LPVNVISDVTPSPYGFHLFKVVEKKPAQRRTLEQARAEIAEKLGREKRAGAQAEYLEALRKRAQIDIDEKALAAVTP

Sequences:

>Translated_317_residues
MRPALAPILIATALAAGCGRCGGARSGERPAPGAVAVVNGEPIAPDAVARELRDAQAGAEGQGQATGDVLRRRVLDDLVD
RALLLQQARARSIVVGQDQVERAFLRLRAEYPGTHFDDLLAQERLSQAELKARLKDQLTVERLFEQEVFPQVQVVDAEVE
RYYAEHGAEFQEPERVHVLQIVVASREEAAQVREKLRRNPQTFAEVARRSSIAPEGKSGGDLGLIGRGAGFPEVFDTCFS
LPVNVISDVTPSPYGFHLFKVVEKKPAQRRTLEQARAEIAEKLGREKRAGAQAEYLEALRKRAQIDIDEKALAAVTP
>Mature_317_residues
MRPALAPILIATALAAGCGRCGGARSGERPAPGAVAVVNGEPIAPDAVARELRDAQAGAEGQGQATGDVLRRRVLDDLVD
RALLLQQARARSIVVGQDQVERAFLRLRAEYPGTHFDDLLAQERLSQAELKARLKDQLTVERLFEQEVFPQVQVVDAEVE
RYYAEHGAEFQEPERVHVLQIVVASREEAAQVREKLRRNPQTFAEVARRSSIAPEGKSGGDLGLIGRGAGFPEVFDTCFS
LPVNVISDVTPSPYGFHLFKVVEKKPAQRRTLEQARAEIAEKLGREKRAGAQAEYLEALRKRAQIDIDEKALAAVTP

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34696; Mature: 34696

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPALAPILIATALAAGCGRCGGARSGERPAPGAVAVVNGEPIAPDAVARELRDAQAGAE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
GQGQATGDVLRRRVLDDLVDRALLLQQARARSIVVGQDQVERAFLRLRAEYPGTHFDDLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHCCCCCHHHHHH
AQERLSQAELKARLKDQLTVERLFEQEVFPQVQVVDAEVERYYAEHGAEFQEPERVHVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IVVASREEAAQVREKLRRNPQTFAEVARRSSIAPEGKSGGDLGLIGRGAGFPEVFDTCFS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
LPVNVISDVTPSPYGFHLFKVVEKKPAQRRTLEQARAEIAEKLGREKRAGAQAEYLEALR
CHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHH
KRAQIDIDEKALAAVTP
HHHCCCCCHHHHHCCCC
>Mature Secondary Structure
MRPALAPILIATALAAGCGRCGGARSGERPAPGAVAVVNGEPIAPDAVARELRDAQAGAE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
GQGQATGDVLRRRVLDDLVDRALLLQQARARSIVVGQDQVERAFLRLRAEYPGTHFDDLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHCCCCCHHHHHH
AQERLSQAELKARLKDQLTVERLFEQEVFPQVQVVDAEVERYYAEHGAEFQEPERVHVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IVVASREEAAQVREKLRRNPQTFAEVARRSSIAPEGKSGGDLGLIGRGAGFPEVFDTCFS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
LPVNVISDVTPSPYGFHLFKVVEKKPAQRRTLEQARAEIAEKLGREKRAGAQAEYLEALR
CHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHH
KRAQIDIDEKALAAVTP
HHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]