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The map label for this gene is macB [H]

Identifier: 220919389

GI number: 220919389

Start: 4802239

End: 4803480

Strand: Direct

Name: macB [H]

Synonym: A2cp1_4310

Alternate gene names: 220919389

Gene position: 4802239-4803480 (Clockwise)

Preceding gene: 220919388

Following gene: 220919390

Centisome position: 95.48

GC content: 70.29

Gene sequence:

>1242_bases
ATGAACGCCTTCCTCGACACGCTGGCGATGGCCATCGGCACGCTGCGCGGGAACGTGCTGCGGTCGATGCTGACGCTGCT
CGGCATCGTGATCGGCGCCTGCACCGTGGTGGCGATGATGTCGCTCACCGAGGGGCTCCGCCTCAAGATGACGACCGACT
TCGCCATGCTGGGCGCCGGCGCGTTCCAGGTCCAGAAGTGGCCGCACATGAACTTCGGGCCGATCGACTGGCGCAAGTAC
GAGCAGCGCAAGCCGCTCACCCGCGAGCAGGGCGAGGCGCTCCGGTCGCTCCCGCACGTGAAGTTCGTGTCGATCGAGGA
GTACCCGAGCGGCGACGGCAACGGCGCGGCGGTGGTCTCCACGCCGGAGCGGGCCACCCGGCGCGAGGTCGCGTTCGGCG
GGGTGCTCCCCGACTACGAGCCCGCCAACGGCGTCACCGTCGGCCAGGGTCGGTTCATCAGCACCACCGACGTGCTGCTC
GGCCGCCGGGTGACGTTCGTGGGCACCGACGTGGTGGACGTGCTGTTCCCGAAGATGGACCCCATCGGCCGCGAGGTGCG
CATCCGCGGCGTGCCGTTCGAGATCATCGGCGTCTCGATGAAGCAGGGGAGCATCTTCGGCCAGTCGAAGGACTCCTGGG
CGGTGGTGCCCTGGACCGCCTACGAGGTCGCGTTCGGGCGGAACCGCAACAACAACATCGCCATCCAGGCCACCTCGCCC
GAGGACCTGCCGCTCGCCATGGACGAGGTGGTCGCGGCGTTGCGGCGGCTGCGCGGGCTCGGGCCGCAGGAGGAGAACGA
CTTCGAGCTGTTCTCCAACGACACCTCGGCGGAGATGTTCGACAACCTGGCGCGGATGGTGGGCGCGGCCACGTTCGGCG
TGTGCGCGCTGGCGCTGCTGGTCGGCGGCATCGGCGTCATGAACATCATGCTCGTGTCGGTGACCGAGCGGACCCGGGAG
ATCGGCGTCCGGATGGCGCTGGGCGCCCGGCGCGGCCGCATCCTGATGCAGTTCCTGCTCGAGTCGATCACGCTCTCCGG
CCTGGGCGGCCTGGTGGGCGTCCTGGTCGGCGCCGGGCTCGCCCTGGGCGCCCGCGCCGTGTTCGACGTTCCGGCGAGCA
TCCCGGCGTGGGCGGTGATACTCTCCCTCGCCTCCGCCTGCGGGGCCGGGTTGCTGTTCGGCATCTACCCGGCCGCCCGA
GCCTCGAAGCTCGACCCGGTGGAGGCGATGCGGATCGAATAG

Upstream 100 bases:

>100_bases
CGCTCGGGCTCGGCTTCTCCGCGGGCGTGGGCCTGCTGTTCGGCTCCTGGCCGGCCTGGCGCGCCGCGCGCCTCGATCCG
GTCGAGGCGCTGAGGTACGA

Downstream 100 bases:

>100_bases
GAGAGCGGCGGCGCGTGGACAGAGCGAAGGTGATGAGAGAGGTACGGGGCTGGACGCTCACCATCCTCGCGGTGCTCGCC
TTCCGGACGTTCCTCTACGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MNAFLDTLAMAIGTLRGNVLRSMLTLLGIVIGACTVVAMMSLTEGLRLKMTTDFAMLGAGAFQVQKWPHMNFGPIDWRKY
EQRKPLTREQGEALRSLPHVKFVSIEEYPSGDGNGAAVVSTPERATRREVAFGGVLPDYEPANGVTVGQGRFISTTDVLL
GRRVTFVGTDVVDVLFPKMDPIGREVRIRGVPFEIIGVSMKQGSIFGQSKDSWAVVPWTAYEVAFGRNRNNNIAIQATSP
EDLPLAMDEVVAALRRLRGLGPQEENDFELFSNDTSAEMFDNLARMVGAATFGVCALALLVGGIGVMNIMLVSVTERTRE
IGVRMALGARRGRILMQFLLESITLSGLGGLVGVLVGAGLALGARAVFDVPASIPAWAVILSLASACGAGLLFGIYPAAR
ASKLDPVEAMRIE

Sequences:

>Translated_413_residues
MNAFLDTLAMAIGTLRGNVLRSMLTLLGIVIGACTVVAMMSLTEGLRLKMTTDFAMLGAGAFQVQKWPHMNFGPIDWRKY
EQRKPLTREQGEALRSLPHVKFVSIEEYPSGDGNGAAVVSTPERATRREVAFGGVLPDYEPANGVTVGQGRFISTTDVLL
GRRVTFVGTDVVDVLFPKMDPIGREVRIRGVPFEIIGVSMKQGSIFGQSKDSWAVVPWTAYEVAFGRNRNNNIAIQATSP
EDLPLAMDEVVAALRRLRGLGPQEENDFELFSNDTSAEMFDNLARMVGAATFGVCALALLVGGIGVMNIMLVSVTERTRE
IGVRMALGARRGRILMQFLLESITLSGLGGLVGVLVGAGLALGARAVFDVPASIPAWAVILSLASACGAGLLFGIYPAAR
ASKLDPVEAMRIE
>Mature_413_residues
MNAFLDTLAMAIGTLRGNVLRSMLTLLGIVIGACTVVAMMSLTEGLRLKMTTDFAMLGAGAFQVQKWPHMNFGPIDWRKY
EQRKPLTREQGEALRSLPHVKFVSIEEYPSGDGNGAAVVSTPERATRREVAFGGVLPDYEPANGVTVGQGRFISTTDVLL
GRRVTFVGTDVVDVLFPKMDPIGREVRIRGVPFEIIGVSMKQGSIFGQSKDSWAVVPWTAYEVAFGRNRNNNIAIQATSP
EDLPLAMDEVVAALRRLRGLGPQEENDFELFSNDTSAEMFDNLARMVGAATFGVCALALLVGGIGVMNIMLVSVTERTRE
IGVRMALGARRGRILMQFLLESITLSGLGGLVGVLVGAGLALGARAVFDVPASIPAWAVILSLASACGAGLLFGIYPAAR
ASKLDPVEAMRIE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=426, Percent_Identity=30.0469483568075, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44319; Mature: 44319

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFLDTLAMAIGTLRGNVLRSMLTLLGIVIGACTVVAMMSLTEGLRLKMTTDFAMLGAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCC
AFQVQKWPHMNFGPIDWRKYEQRKPLTREQGEALRSLPHVKFVSIEEYPSGDGNGAAVVS
HHEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEE
TPERATRREVAFGGVLPDYEPANGVTVGQGRFISTTDVLLGRRVTFVGTDVVDVLFPKMD
CCCHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEHHHHHHCCEEEEECHHHHHHHHCCCC
PIGREVRIRGVPFEIIGVSMKQGSIFGQSKDSWAVVPWTAYEVAFGRNRNNNIAIQATSP
CCCCEEEEECCCEEEEEEEEECCCCCCCCCCCEEEECEEHEEEEECCCCCCCEEEEECCC
EDLPLAMDEVVAALRRLRGLGPQEENDFELFSNDTSAEMFDNLARMVGAATFGVCALALL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VGGIGVMNIMLVSVTERTREIGVRMALGARRGRILMQFLLESITLSGLGGLVGVLVGAGL
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALGARAVFDVPASIPAWAVILSLASACGAGLLFGIYPAARASKLDPVEAMRIE
HHCCHHEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MNAFLDTLAMAIGTLRGNVLRSMLTLLGIVIGACTVVAMMSLTEGLRLKMTTDFAMLGAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCC
AFQVQKWPHMNFGPIDWRKYEQRKPLTREQGEALRSLPHVKFVSIEEYPSGDGNGAAVVS
HHEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEE
TPERATRREVAFGGVLPDYEPANGVTVGQGRFISTTDVLLGRRVTFVGTDVVDVLFPKMD
CCCHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEHHHHHHCCEEEEECHHHHHHHHCCCC
PIGREVRIRGVPFEIIGVSMKQGSIFGQSKDSWAVVPWTAYEVAFGRNRNNNIAIQATSP
CCCCEEEEECCCEEEEEEEEECCCCCCCCCCCEEEECEEHEEEEECCCCCCCEEEEECCC
EDLPLAMDEVVAALRRLRGLGPQEENDFELFSNDTSAEMFDNLARMVGAATFGVCALALL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VGGIGVMNIMLVSVTERTREIGVRMALGARRGRILMQFLLESITLSGLGGLVGVLVGAGL
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALGARAVFDVPASIPAWAVILSLASACGAGLLFGIYPAARASKLDPVEAMRIE
HHCCHHEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA