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The map label for this gene is macB [H]

Identifier: 220919388

GI number: 220919388

Start: 4800980

End: 4802242

Strand: Direct

Name: macB [H]

Synonym: A2cp1_4309

Alternate gene names: 220919388

Gene position: 4800980-4802242 (Clockwise)

Preceding gene: 220919387

Following gene: 220919389

Centisome position: 95.46

GC content: 72.6

Gene sequence:

>1263_bases
ATGAACCGCGTCGCCCGGGCCTTCGTCCGCGCCGGCGCGGAGCTCGCCGAGTCGGTGCGCATCGCGCTCGAGTCCCTGAT
CGGCGCGCGCCTGCGCAGCTTCCTCACCACGCTCGGCATCGTCATCGGCGTGATGACGGTGATCGCCATCGTCGCCATCA
TCCAGGGGCTGAACCGCTCGTTCGAGGGGCAGATCGCGAACCTGGGCGCGAACACGCTCTACGTCTCCAAGTTCGCCTGG
CTGGCGCAGGGCCGCGGCGAGTGGTGGGAGATGCGGAACCGCAAGGACCTGGGCAAGCGCGAGCTCGCGGCGGTGGAGCG
CGAGGTGACGCTCGCCACGGCGGTCGCGCCGCAGGCGGGAACGCGCGGGACGGTCACCCGGCTCGACAAGGAGCTCTCCG
GCGTCCAGCTCATCGGCACGAACGCGCGCTACCTCGACACCGGGGCCGGCTCGGTGCAGGCCGGGCGCTTCCTCACCGAC
ACCGACGTGGACCTGGAGCGCGCCGCCGCGGTGCTGGGGCACGCGGTGGCGGAGCGGCTGTTCCCGGGCGCCTCGCCGGA
GACCGTGCTCGGCCAGCGCGTCACGCTGGAGGGCCACCCGTTCACGGTGGTGGGGGTGATGGCGAAGCGCGGGCAGATGC
TCGGCATGGACATGGACAGCAACGTCATCCTGCCGTTCACGACGTTCCTGCGCGACCTCGGCTCGAAGCGCTCCCTCAAC
CTGGCGGTGGCGGCCGCGCCGGAGAACCTCTCCGCGCTCGAGGACCAGATCGTCGGGGTGCTGCGCCGGGTCCGGCAGGT
GGCCCCGGACAAGAAGGACGACTTCGCCATCAACCGGCAGGAGCAGTTCCTGCGCATCTACCGCCAGCTCACCGGCGCGC
TGTACGGCGTCGCCATCGGCGTGGGGCTCATCACGCTGGTGGTGGGCGGCATCGGCATCATGAACATCATGCTGGTGTCG
GTGACCGAGCGGACCCGCGAGATCGGGGTGCGGCGCGCGCTCGGGGCCCGGCGGCGCACCATCCTCCTGCAGTTCCTGAT
CGAGTCGTCGGTGGTGGCGGCGCTGGGCGGCGCGGTGGGCACCACGCTCGGCCTCGGGGTGGCGCAGCTCGTGGCGCTGC
TCACGCCGCTCGCCGCGGCGGTGACGCCGTCGGCGGTGGCGCTCGGGCTCGGCTTCTCCGCGGGCGTGGGCCTGCTGTTC
GGCTCCTGGCCGGCCTGGCGCGCCGCGCGCCTCGATCCGGTCGAGGCGCTGAGGTACGAATGA

Upstream 100 bases:

>100_bases
CGGCGCGCTGCCCGCGCGCCATCCGGCTGTCCGACGGCCGGGTGGTGGGCGACGGCCCCGGCGCCGAGGTGGCGCTGTCC
GGCGCCCGGGCGGTCCACGC

Downstream 100 bases:

>100_bases
ACGCCTTCCTCGACACGCTGGCGATGGCCATCGGCACGCTGCGCGGGAACGTGCTGCGGTCGATGCTGACGCTGCTCGGC
ATCGTGATCGGCGCCTGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MNRVARAFVRAGAELAESVRIALESLIGARLRSFLTTLGIVIGVMTVIAIVAIIQGLNRSFEGQIANLGANTLYVSKFAW
LAQGRGEWWEMRNRKDLGKRELAAVEREVTLATAVAPQAGTRGTVTRLDKELSGVQLIGTNARYLDTGAGSVQAGRFLTD
TDVDLERAAAVLGHAVAERLFPGASPETVLGQRVTLEGHPFTVVGVMAKRGQMLGMDMDSNVILPFTTFLRDLGSKRSLN
LAVAAAPENLSALEDQIVGVLRRVRQVAPDKKDDFAINRQEQFLRIYRQLTGALYGVAIGVGLITLVVGGIGIMNIMLVS
VTERTREIGVRRALGARRRTILLQFLIESSVVAALGGAVGTTLGLGVAQLVALLTPLAAAVTPSAVALGLGFSAGVGLLF
GSWPAWRAARLDPVEALRYE

Sequences:

>Translated_420_residues
MNRVARAFVRAGAELAESVRIALESLIGARLRSFLTTLGIVIGVMTVIAIVAIIQGLNRSFEGQIANLGANTLYVSKFAW
LAQGRGEWWEMRNRKDLGKRELAAVEREVTLATAVAPQAGTRGTVTRLDKELSGVQLIGTNARYLDTGAGSVQAGRFLTD
TDVDLERAAAVLGHAVAERLFPGASPETVLGQRVTLEGHPFTVVGVMAKRGQMLGMDMDSNVILPFTTFLRDLGSKRSLN
LAVAAAPENLSALEDQIVGVLRRVRQVAPDKKDDFAINRQEQFLRIYRQLTGALYGVAIGVGLITLVVGGIGIMNIMLVS
VTERTREIGVRRALGARRRTILLQFLIESSVVAALGGAVGTTLGLGVAQLVALLTPLAAAVTPSAVALGLGFSAGVGLLF
GSWPAWRAARLDPVEALRYE
>Mature_420_residues
MNRVARAFVRAGAELAESVRIALESLIGARLRSFLTTLGIVIGVMTVIAIVAIIQGLNRSFEGQIANLGANTLYVSKFAW
LAQGRGEWWEMRNRKDLGKRELAAVEREVTLATAVAPQAGTRGTVTRLDKELSGVQLIGTNARYLDTGAGSVQAGRFLTD
TDVDLERAAAVLGHAVAERLFPGASPETVLGQRVTLEGHPFTVVGVMAKRGQMLGMDMDSNVILPFTTFLRDLGSKRSLN
LAVAAAPENLSALEDQIVGVLRRVRQVAPDKKDDFAINRQEQFLRIYRQLTGALYGVAIGVGLITLVVGGIGIMNIMLVS
VTERTREIGVRRALGARRRTILLQFLIESSVVAALGGAVGTTLGLGVAQLVALLTPLAAAVTPSAVALGLGFSAGVGLLF
GSWPAWRAARLDPVEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=405, Percent_Identity=31.358024691358, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44788; Mature: 44788

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVARAFVRAGAELAESVRIALESLIGARLRSFLTTLGIVIGVMTVIAIVAIIQGLNRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FEGQIANLGANTLYVSKFAWLAQGRGEWWEMRNRKDLGKRELAAVEREVTLATAVAPQAG
CCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCCC
TRGTVTRLDKELSGVQLIGTNARYLDTGAGSVQAGRFLTDTDVDLERAAAVLGHAVAERL
CCCHHHHHHHHHCCEEEEECCCEEEECCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
FPGASPETVLGQRVTLEGHPFTVVGVMAKRGQMLGMDMDSNVILPFTTFLRDLGSKRSLN
CCCCCCCHHCCCEEEECCCCEEEEEEHHHCCCEECCCCCCCEEHHHHHHHHHCCCCCCCE
LAVAAAPENLSALEDQIVGVLRRVRQVAPDKKDDFAINRQEQFLRIYRQLTGALYGVAIG
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGLITLVVGGIGIMNIMLVSVTERTREIGVRRALGARRRTILLQFLIESSVVAALGGAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTLGLGVAQLVALLTPLAAAVTPSAVALGLGFSAGVGLLFGSWPAWRAARLDPVEALRYE
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHCHHHHHCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MNRVARAFVRAGAELAESVRIALESLIGARLRSFLTTLGIVIGVMTVIAIVAIIQGLNRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FEGQIANLGANTLYVSKFAWLAQGRGEWWEMRNRKDLGKRELAAVEREVTLATAVAPQAG
CCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCCC
TRGTVTRLDKELSGVQLIGTNARYLDTGAGSVQAGRFLTDTDVDLERAAAVLGHAVAERL
CCCHHHHHHHHHCCEEEEECCCEEEECCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
FPGASPETVLGQRVTLEGHPFTVVGVMAKRGQMLGMDMDSNVILPFTTFLRDLGSKRSLN
CCCCCCCHHCCCEEEECCCCEEEEEEHHHCCCEECCCCCCCEEHHHHHHHHHCCCCCCCE
LAVAAAPENLSALEDQIVGVLRRVRQVAPDKKDDFAINRQEQFLRIYRQLTGALYGVAIG
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGLITLVVGGIGIMNIMLVSVTERTREIGVRRALGARRRTILLQFLIESSVVAALGGAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTLGLGVAQLVALLTPLAAAVTPSAVALGLGFSAGVGLLFGSWPAWRAARLDPVEALRYE
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHCHHHHHCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA