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The map label for this gene is murB

Identifier: 220918998

GI number: 220918998

Start: 4353784

End: 4354773

Strand: Direct

Name: murB

Synonym: A2cp1_3913

Alternate gene names: 220918998

Gene position: 4353784-4354773 (Clockwise)

Preceding gene: 220918997

Following gene: 220918999

Centisome position: 86.57

GC content: 77.98

Gene sequence:

>990_bases
ATGACCTGGCGCGACGAGATCGCCCGCCGCGTCCGCGGCGAGCACCTGCGCGACGCGCCGCTCGCGCCGCGCACCGCGGT
GCGGGTGGGCGGTCCGGCCGACCTGCTCTGCCGCCCCGCCGACGGCGACGCGCTCTCGGCGCTGCTCCGCGCGGTGCGCG
AGCTGGGGGTGCCGCTCTCGGTGCTGGGCGGCGGCGCGAACACGCTGGTCGCGGACGCCGGCGTGCGCGGGGTGGTGCTG
CGGCTGCCGCAGGAGTTCCCGGGCGAGTCCACCGACGGTGACACGCTGGTCCTCTCCGCCGGCGCGCCCATCTCGCGGCT
GCCGGCGCGGGCGCACGCGCACGGCCTCGTCGGCATGGAGTTCCTGGGCGGGATCCCGGGGACGCTGGGCGGCGCGGCCG
CCATGAACGCCGGCACGCGCCTGGGCGAGATGAAGGACGTCGTCACCCGGCTCGAGCTCGCCACCCCCGACGGCACCGGC
TTCGTGCCGGCCTCGGCGCTGGGCTACGCCTACCGGACCTGCCGGCTCCCGCCCGGCGCGGTCATCGCCCGCGTCGAGGT
GCGGCTCCACCCCGGCGACGTGGCCGCGAGCGAGGCGCTCATGCGCGAGGACCGCGAGCGCCGCCGCGCCACCCAGCCGC
TCTACCGGCCCACCTTCGGCTCCACCTTCACGAACCCGCCGGGCGAGTACGCCGGGCGCCTGGTGGAGGCGGTCGGGCTG
AAGGGGCACCGCGTCGGCAACGCGATCTGGTCGCCGGTGCACGCGAACTTCGTGACGAACCTGGGCGGCGCCACCGCCCG
CGACGTGCTCGCGCTCGTGCGGCTGGCGCGGGCCCGGGTGCAGGAGCGGTTCGGGATCGCGCTCGAGACCGAGGTCCGGC
TCCTGGGCGAGTTCCTCGAAGAGGATCTGGAAGGGCTGGACGGGCACGCCGCCGCGGGCGGCGGCCCCGGCGCGGCGAGC
GGGGGCGTGCGCCCCCCGGAGGCGACATGA

Upstream 100 bases:

>100_bases
GACGTGACCGCCGCCGGCCCGGAGCTGCTGGCGCTGCTCGAGCGATGAGCGCTCCCTCCCCCCGCCCGCGGCGCGGCCCG
GCCCGCCCGGCCCCCCGCGC

Downstream 100 bases:

>100_bases
GCACGTGGACGGGCAAGCGGGTGGCGGTGCTGTACGGCGGACGCTCCAGCGAGCGCGAGGTGTCGCTCAGGACCGGCGCC
GCCTGCGCCGACGCGCTCCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTWRDEIARRVRGEHLRDAPLAPRTAVRVGGPADLLCRPADGDALSALLRAVRELGVPLSVLGGGANTLVADAGVRGVVL
RLPQEFPGESTDGDTLVLSAGAPISRLPARAHAHGLVGMEFLGGIPGTLGGAAAMNAGTRLGEMKDVVTRLELATPDGTG
FVPASALGYAYRTCRLPPGAVIARVEVRLHPGDVAASEALMREDRERRRATQPLYRPTFGSTFTNPPGEYAGRLVEAVGL
KGHRVGNAIWSPVHANFVTNLGGATARDVLALVRLARARVQERFGIALETEVRLLGEFLEEDLEGLDGHAAAGGGPGAAS
GGVRPPEAT

Sequences:

>Translated_329_residues
MTWRDEIARRVRGEHLRDAPLAPRTAVRVGGPADLLCRPADGDALSALLRAVRELGVPLSVLGGGANTLVADAGVRGVVL
RLPQEFPGESTDGDTLVLSAGAPISRLPARAHAHGLVGMEFLGGIPGTLGGAAAMNAGTRLGEMKDVVTRLELATPDGTG
FVPASALGYAYRTCRLPPGAVIARVEVRLHPGDVAASEALMREDRERRRATQPLYRPTFGSTFTNPPGEYAGRLVEAVGL
KGHRVGNAIWSPVHANFVTNLGGATARDVLALVRLARARVQERFGIALETEVRLLGEFLEEDLEGLDGHAAAGGGPGAAS
GGVRPPEAT
>Mature_328_residues
TWRDEIARRVRGEHLRDAPLAPRTAVRVGGPADLLCRPADGDALSALLRAVRELGVPLSVLGGGANTLVADAGVRGVVLR
LPQEFPGESTDGDTLVLSAGAPISRLPARAHAHGLVGMEFLGGIPGTLGGAAAMNAGTRLGEMKDVVTRLELATPDGTGF
VPASALGYAYRTCRLPPGAVIARVEVRLHPGDVAASEALMREDRERRRATQPLYRPTFGSTFTNPPGEYAGRLVEAVGLK
GHRVGNAIWSPVHANFVTNLGGATARDVLALVRLARARVQERFGIALETEVRLLGEFLEEDLEGLDGHAAAGGGPGAASG
GVRPPEAT

Specific function: Cell wall formation

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURB_ANAD2 (B8J8F0)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002494302.1
- ProteinModelPortal:   B8J8F0
- SMR:   B8J8F0
- GeneID:   7297253
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_3913
- HOGENOM:   HBG686573
- ProtClustDB:   PRK14652
- GO:   GO:0005737
- HAMAP:   MF_00037
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094
- Gene3D:   G3DSA:3.30.465.10
- Gene3D:   G3DSA:3.30.43.10
- Gene3D:   G3DSA:3.90.78.10
- PANTHER:   PTHR21071
- TIGRFAMs:   TIGR00179

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C; SSF56176 FAD-binding_2; SSF56194 MurB_C

EC number: =1.1.1.158

Molecular weight: Translated: 34303; Mature: 34171

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS51387 FAD_PCMH

Important sites: ACT_SITE 172-172 ACT_SITE 221-221 ACT_SITE 291-291

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWRDEIARRVRGEHLRDAPLAPRTAVRVGGPADLLCRPADGDALSALLRAVRELGVPLS
CCCHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHEEECCCCHHHHHHHHHHHHHCCCEE
VLGGGANTLVADAGVRGVVLRLPQEFPGESTDGDTLVLSAGAPISRLPARAHAHGLVGME
EECCCCCCEEECCCCCEEEEECCHHCCCCCCCCCEEEEECCCCHHHCCHHHHHCCCHHHH
FLGGIPGTLGGAAAMNAGTRLGEMKDVVTRLELATPDGTGFVPASALGYAYRTCRLPPGA
HHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
VIARVEVRLHPGDVAASEALMREDRERRRATQPLYRPTFGSTFTNPPGEYAGRLVEAVGL
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
KGHRVGNAIWSPVHANFVTNLGGATARDVLALVRLARARVQERFGIALETEVRLLGEFLE
CCCHHCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EDLEGLDGHAAAGGGPGAASGGVRPPEAT
HHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TWRDEIARRVRGEHLRDAPLAPRTAVRVGGPADLLCRPADGDALSALLRAVRELGVPLS
CCHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHEEECCCCHHHHHHHHHHHHHCCCEE
VLGGGANTLVADAGVRGVVLRLPQEFPGESTDGDTLVLSAGAPISRLPARAHAHGLVGME
EECCCCCCEEECCCCCEEEEECCHHCCCCCCCCCEEEEECCCCHHHCCHHHHHCCCHHHH
FLGGIPGTLGGAAAMNAGTRLGEMKDVVTRLELATPDGTGFVPASALGYAYRTCRLPPGA
HHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
VIARVEVRLHPGDVAASEALMREDRERRRATQPLYRPTFGSTFTNPPGEYAGRLVEAVGL
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
KGHRVGNAIWSPVHANFVTNLGGATARDVLALVRLARARVQERFGIALETEVRLLGEFLE
CCCHHCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EDLEGLDGHAAAGGGPGAASGGVRPPEAT
HHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA