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The map label for this gene is hycD [H]

Identifier: 220918883

GI number: 220918883

Start: 4218932

End: 4219840

Strand: Direct

Name: hycD [H]

Synonym: A2cp1_3797

Alternate gene names: 220918883

Gene position: 4218932-4219840 (Clockwise)

Preceding gene: 220918882

Following gene: 220918884

Centisome position: 83.89

GC content: 73.27

Gene sequence:

>909_bases
ATGGTCCTGCGCACCGCGCTCCACGTGGTCGCGCTGCTCGTGCTCCCGCCGCTGCTGCTCGGCGTGATCAACCGCGTGAA
GTCCATCGTCGGCGGCCGCCGCGGCCCGCCACTGCTGCAGCCGTACCTCGACCTCGCCAAGCTGCTGCGCAAGGGGGCGG
TCTACAGCCGGACCACCACCTGGGTGTTCCGCGCCGGCCCGGTGATCGGGCTCGCGGCGGTCGCCTCCGCCGGCCTGCTC
CTCTCCATGGGCGGCGCCCCCGCGCCCATCGCGTTCACCGGCGACTTCGTCCTGTTCGCCTACCTGCTCGGCCTGGGCCG
CTTCTTCACCGCGCTCGCCGCGCTCGACACCGGCTCGTCGTTCGAGGGCATGGGCGCGGCGCGCGAGGTGACGTTCGCGA
GCCTGGCCGAGCCGGCGCTGTTCCTCTGCCTGCTGGTGCTGGCGCGCGCCACCGGCTCGCTGTCGCTCTCCGGCATGCTC
GGTCCCGACCTCGACGCGGCCTGGTCCTCGGCGGCGCCGGGCCTCCTGCTCGCCGCCATCGGCCTGTTCGTGGTGGCGCT
CGCGGAGTGCTCGCGCATCCCGGTGGACGACCCCAACACGCACCTCGAGCTCACCATGATCCACGAGGTGATGGTGCTCG
ACCACGGCGGGCCCGACCTCGCGCTCATCCTGTACGGCGCGGCCATGAAGATGTTCCTGTTCGGCGCCCTGCTCTCCCGC
CTGGTGCTCGGCCACGGCGCCGGCGCGCTCGCCTCGGAGGCGCTGTTCTTCCTGGGCGTGATCGCGTTCGCGGTGGCGGT
GGGCGTGGTCGAGTCGGTGATGGCGCGGCTGCGCATCGTGCGCGTGCCGCAGCTCCTGGTGGGCGCCTCGGTGCTGTCCG
CCTTCGCCCTGGTCCTCCTGCTCCGGTGA

Upstream 100 bases:

>100_bases
CGCGCCTCCTCTACCTCCGCAGGATCCACTTCCAGATGCTGCTCGTGCTCGTGACGCTCCTCGCCGTCCTCGCCTGGGGG
TTCGCGTGGTGAACGCACCC

Downstream 100 bases:

>100_bases
CCCCGTGACCTCCCTCACCGACCTCGTCTTCATCCTCGTCGTCGTCATCGACTTCTTCCTGCTCGCCTCGAGCCGGCTCG
GCGCCGCCATCCGCGCGGTC

Product: respiratory-chain NADH dehydrogenase, subunit 1

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVLRTALHVVALLVLPPLLLGVINRVKSIVGGRRGPPLLQPYLDLAKLLRKGAVYSRTTTWVFRAGPVIGLAAVASAGLL
LSMGGAPAPIAFTGDFVLFAYLLGLGRFFTALAALDTGSSFEGMGAAREVTFASLAEPALFLCLLVLARATGSLSLSGML
GPDLDAAWSSAAPGLLLAAIGLFVVALAECSRIPVDDPNTHLELTMIHEVMVLDHGGPDLALILYGAAMKMFLFGALLSR
LVLGHGAGALASEALFFLGVIAFAVAVGVVESVMARLRIVRVPQLLVGASVLSAFALVLLLR

Sequences:

>Translated_302_residues
MVLRTALHVVALLVLPPLLLGVINRVKSIVGGRRGPPLLQPYLDLAKLLRKGAVYSRTTTWVFRAGPVIGLAAVASAGLL
LSMGGAPAPIAFTGDFVLFAYLLGLGRFFTALAALDTGSSFEGMGAAREVTFASLAEPALFLCLLVLARATGSLSLSGML
GPDLDAAWSSAAPGLLLAAIGLFVVALAECSRIPVDDPNTHLELTMIHEVMVLDHGGPDLALILYGAAMKMFLFGALLSR
LVLGHGAGALASEALFFLGVIAFAVAVGVVESVMARLRIVRVPQLLVGASVLSAFALVLLLR
>Mature_302_residues
MVLRTALHVVALLVLPPLLLGVINRVKSIVGGRRGPPLLQPYLDLAKLLRKGAVYSRTTTWVFRAGPVIGLAAVASAGLL
LSMGGAPAPIAFTGDFVLFAYLLGLGRFFTALAALDTGSSFEGMGAAREVTFASLAEPALFLCLLVLARATGSLSLSGML
GPDLDAAWSSAAPGLLLAAIGLFVVALAECSRIPVDDPNTHLELTMIHEVMVLDHGGPDLALILYGAAMKMFLFGALLSR
LVLGHGAGALASEALFFLGVIAFAVAVGVVESVMARLRIVRVPQLLVGASVLSAFALVLLLR

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=291, Percent_Identity=27.1477663230241, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082115, Length=240, Percent_Identity=34.5833333333333, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 31318; Mature: 31318

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLRTALHVVALLVLPPLLLGVINRVKSIVGGRRGPPLLQPYLDLAKLLRKGAVYSRTTT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHE
WVFRAGPVIGLAAVASAGLLLSMGGAPAPIAFTGDFVLFAYLLGLGRFFTALAALDTGSS
EEEECCCHHHHHHHHHCCHHEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEGMGAAREVTFASLAEPALFLCLLVLARATGSLSLSGMLGPDLDAAWSSAAPGLLLAAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCHHHHHHH
GLFVVALAECSRIPVDDPNTHLELTMIHEVMVLDHGGPDLALILYGAAMKMFLFGALLSR
HHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
LVLGHGAGALASEALFFLGVIAFAVAVGVVESVMARLRIVRVPQLLVGASVLSAFALVLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LR
CC
>Mature Secondary Structure
MVLRTALHVVALLVLPPLLLGVINRVKSIVGGRRGPPLLQPYLDLAKLLRKGAVYSRTTT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHE
WVFRAGPVIGLAAVASAGLLLSMGGAPAPIAFTGDFVLFAYLLGLGRFFTALAALDTGSS
EEEECCCHHHHHHHHHCCHHEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEGMGAAREVTFASLAEPALFLCLLVLARATGSLSLSGMLGPDLDAAWSSAAPGLLLAAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCHHHHHHH
GLFVVALAECSRIPVDDPNTHLELTMIHEVMVLDHGGPDLALILYGAAMKMFLFGALLSR
HHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
LVLGHGAGALASEALFFLGVIAFAVAVGVVESVMARLRIVRVPQLLVGASVLSAFALVLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]