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The map label for this gene is acoR [H]

Identifier: 220917198

GI number: 220917198

Start: 2335260

End: 2336624

Strand: Reverse

Name: acoR [H]

Synonym: A2cp1_2095

Alternate gene names: 220917198

Gene position: 2336624-2335260 (Counterclockwise)

Preceding gene: 220917203

Following gene: 220917197

Centisome position: 46.46

GC content: 77.0

Gene sequence:

>1365_bases
ATGGAGCTCTTGCGCGCACGAACCGAGCTGACGGCGGCCTGGCAGGCGTTCCTCGTGGACGGACGGCTGCCGCCGCGGAT
CCGTCCCGAGATCCGCCGCTCGTGGCTCCGGGTCCGCGAGGAGGCGCGCGTGGACCCGCGGCTGCGCGCCTCCCCGCTCG
CGGTCGGGCCCGAGGACGTGGTCGCGCGCGGCGAGGGCGACGACGCCGCCCGGATCGCCGCCGGCGTGGTGGCGCACTAC
GCCGAGCGGCTGCGCGACGGCGGGCACGTCGTCGCCTACTTCGACGCGGACGGGGTGATGCTGGCGTGCGACGGCGACCC
GCGGACGCGGCGCGCGCTCGACCGGGTGAACTTCGCGCCCGGCGCGTGCTGGGCGGAGGGCGTCACGGGCACGAACGCGC
CTGGCACCGCGCTCGTGGAGGGGCGGCCGCTGGAGGTGTTCGCCGCGGAGCACTTCGTGGAGGTGCTGCAACCCTGGACC
TGCGCGAGCGCGCCGGTCCGGCTGGGCGGGCGCGTCGTGGGCGCGGTCGACATCACCTCGCCCTGGACCGCCCATCACGC
GTCGCTGCTGCCGACCGCCGAGGCGGTGGCCCAGGTCATCGAGGGCCGGCTCGAGGCCGAGGCGGCGCGGGCGCACGCCG
ACCTCATGATGCACGTGGCCGGCAGCGCGCTCCACGCGCGCGACGACTTCCTGACGGTGGCCTCCCACGAGCTGAAGACG
CCGCTCACGCCGCTCCGCGCGAAGCTGCAGGCGGTGCAGCGCCTGCTCGATCGGACCGAGGGCGAGCTGGATCCGGCCCG
CCTCCGCGCGAGCCTGCGTGGCGCCGACGCGCAGGTGGGCCGCGTGGTTGCGGTCGTGGAGCGGCTGCTCGACGGCGCGC
GCCTGCTGCGGGATCCGATCCGTCCGGCGCCGGAGCCCGTCGATCTCGGCGAGCTGGTGCGCGGCGCGGTGGAGCGGCGG
CGCGACGACCTGCAGCGCCAGGGCTGCCATCCCACCGTGACGGTCGTGGGCGAGGTGACCGGCTGCTGGGATCCGGCGCT
CCTCGACCAGGCGCTCGAGCGGCTCCTCTCGAACGCCGCCCGCTACGCGCCCGGGCCCGTCGAGATCGAGGTGGCCTGGG
ACGGCCCGTCCGCGCGCGTGCTGGTCCGCGATCACGGCCCCGGGATCCTCCCGGACGATCGCGAGCGAATCTTCCTCCCC
TACGAGCGCGCGGTGTCGTGCCGGAACTCGGCCGGCCTCGGCCTGGGCCTGCACGCGGTCCGCGCCATCGCGGCCGCGCA
CGGCGGGACCGTCCACGTGGAGCGCGCGCCGGGCCACGGCAGCACCTTCGTGCTCGCGCTCCCCCGCGTGGCCTCGCCGC
GGTGA

Upstream 100 bases:

>100_bases
TCGACGGCCGTCCGCCCGCGCCCTGACGCAGGGTGTCGTACCGGTAGGGGCAGCGTCCTGCTCGCGGCATGAAGCGGCCA
CCGGCCCTGTTCGCGCGTCG

Downstream 100 bases:

>100_bases
GCGCGCGGCCGCGCGCCCCGCCCGATCGCCGCAACCTGTCGGAACCAAGGACGAATGCGGCGCCCGGCCCCGGCTCGGTC
GGGCGCTCCGCACGGCGCGG

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MELLRARTELTAAWQAFLVDGRLPPRIRPEIRRSWLRVREEARVDPRLRASPLAVGPEDVVARGEGDDAARIAAGVVAHY
AERLRDGGHVVAYFDADGVMLACDGDPRTRRALDRVNFAPGACWAEGVTGTNAPGTALVEGRPLEVFAAEHFVEVLQPWT
CASAPVRLGGRVVGAVDITSPWTAHHASLLPTAEAVAQVIEGRLEAEAARAHADLMMHVAGSALHARDDFLTVASHELKT
PLTPLRAKLQAVQRLLDRTEGELDPARLRASLRGADAQVGRVVAVVERLLDGARLLRDPIRPAPEPVDLGELVRGAVERR
RDDLQRQGCHPTVTVVGEVTGCWDPALLDQALERLLSNAARYAPGPVEIEVAWDGPSARVLVRDHGPGILPDDRERIFLP
YERAVSCRNSAGLGLGLHAVRAIAAAHGGTVHVERAPGHGSTFVLALPRVASPR

Sequences:

>Translated_454_residues
MELLRARTELTAAWQAFLVDGRLPPRIRPEIRRSWLRVREEARVDPRLRASPLAVGPEDVVARGEGDDAARIAAGVVAHY
AERLRDGGHVVAYFDADGVMLACDGDPRTRRALDRVNFAPGACWAEGVTGTNAPGTALVEGRPLEVFAAEHFVEVLQPWT
CASAPVRLGGRVVGAVDITSPWTAHHASLLPTAEAVAQVIEGRLEAEAARAHADLMMHVAGSALHARDDFLTVASHELKT
PLTPLRAKLQAVQRLLDRTEGELDPARLRASLRGADAQVGRVVAVVERLLDGARLLRDPIRPAPEPVDLGELVRGAVERR
RDDLQRQGCHPTVTVVGEVTGCWDPALLDQALERLLSNAARYAPGPVEIEVAWDGPSARVLVRDHGPGILPDDRERIFLP
YERAVSCRNSAGLGLGLHAVRAIAAAHGGTVHVERAPGHGSTFVLALPRVASPR
>Mature_454_residues
MELLRARTELTAAWQAFLVDGRLPPRIRPEIRRSWLRVREEARVDPRLRASPLAVGPEDVVARGEGDDAARIAAGVVAHY
AERLRDGGHVVAYFDADGVMLACDGDPRTRRALDRVNFAPGACWAEGVTGTNAPGTALVEGRPLEVFAAEHFVEVLQPWT
CASAPVRLGGRVVGAVDITSPWTAHHASLLPTAEAVAQVIEGRLEAEAARAHADLMMHVAGSALHARDDFLTVASHELKT
PLTPLRAKLQAVQRLLDRTEGELDPARLRASLRGADAQVGRVVAVVERLLDGARLLRDPIRPAPEPVDLGELVRGAVERR
RDDLQRQGCHPTVTVVGEVTGCWDPALLDQALERLLSNAARYAPGPVEIEVAWDGPSARVLVRDHGPGILPDDRERIFLP
YERAVSCRNSAGLGLGLHAVRAIAAAHGGTVHVERAPGHGSTFVLALPRVASPR

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=219, Percent_Identity=31.9634703196347, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790346, Length=253, Percent_Identity=30.0395256916996, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=27.6315789473684, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=29.8701298701299, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=26.0504201680672, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=26.3636363636364, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=29.3859649122807, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=301, Percent_Identity=25.9136212624585, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081858, Length=137, Percent_Identity=28.4671532846715, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 48918; Mature: 48918

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLRARTELTAAWQAFLVDGRLPPRIRPEIRRSWLRVREEARVDPRLRASPLAVGPEDV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VARGEGDDAARIAAGVVAHYAERLRDGGHVVAYFDADGVMLACDGDPRTRRALDRVNFAP
EECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHCCCCC
GACWAEGVTGTNAPGTALVEGRPLEVFAAEHFVEVLQPWTCASAPVRLGGRVVGAVDITS
CCHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCEEEEEEECCC
PWTAHHASLLPTAEAVAQVIEGRLEAEAARAHADLMMHVAGSALHARDDFLTVASHELKT
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCC
PLTPLRAKLQAVQRLLDRTEGELDPARLRASLRGADAQVGRVVAVVERLLDGARLLRDPI
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
RPAPEPVDLGELVRGAVERRRDDLQRQGCHPTVTVVGEVTGCWDPALLDQALERLLSNAA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
RYAPGPVEIEVAWDGPSARVLVRDHGPGILPDDRERIFLPYERAVSCRNSAGLGLGLHAV
HCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHCCCCCCCCHHHHHH
RAIAAAHGGTVHVERAPGHGSTFVLALPRVASPR
HHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MELLRARTELTAAWQAFLVDGRLPPRIRPEIRRSWLRVREEARVDPRLRASPLAVGPEDV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VARGEGDDAARIAAGVVAHYAERLRDGGHVVAYFDADGVMLACDGDPRTRRALDRVNFAP
EECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHCCCCC
GACWAEGVTGTNAPGTALVEGRPLEVFAAEHFVEVLQPWTCASAPVRLGGRVVGAVDITS
CCHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCEEEEEEECCC
PWTAHHASLLPTAEAVAQVIEGRLEAEAARAHADLMMHVAGSALHARDDFLTVASHELKT
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCC
PLTPLRAKLQAVQRLLDRTEGELDPARLRASLRGADAQVGRVVAVVERLLDGARLLRDPI
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
RPAPEPVDLGELVRGAVERRRDDLQRQGCHPTVTVVGEVTGCWDPALLDQALERLLSNAA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
RYAPGPVEIEVAWDGPSARVLVRDHGPGILPDDRERIFLPYERAVSCRNSAGLGLGLHAV
HCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHCCCCCCCCHHHHHH
RAIAAAHGGTVHVERAPGHGSTFVLALPRVASPR
HHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]