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The map label for this gene is ilvH [H]

Identifier: 220917089

GI number: 220917089

Start: 2243604

End: 2244140

Strand: Direct

Name: ilvH [H]

Synonym: A2cp1_1986

Alternate gene names: 220917089

Gene position: 2243604-2244140 (Clockwise)

Preceding gene: 220917088

Following gene: 220917090

Centisome position: 44.61

GC content: 70.58

Gene sequence:

>537_bases
ATGGAACGGACCGAGACCCCGCAGCCGAACGGCTCCACCCACACCATCAGCCTCCTCGTCGAGAACAAGCCGGGCGTGCT
GCACCGGATCGCCGGGCTGTTCTCGCGGCGCGGCTACAACATCGCGAGCCTCACCGTGGGCCCGACCGAGCGGGCCGAGT
ACTCGCGCATGACCATCGTGGTCCGGCTCTCCTCGAGCCCGGTGGACCAGGTGGTCCGGCAGGTCCAGAAGCTGGTCCCG
GTGGTGGAGGTGCGCGAGCTCTCGCCCCAGGACCTGATCGAGCGCGAGCTGCTGCTCGCGAAGATCCGCACGCCGGAGCG
GAACCACGCCGAGCTCCGGGCGCTGGCCGAGACCTACGAGGCGGTGATCGTGGACGTCTCTCCCGACGCGCTGGTGGTGG
AGGCGAGCGGCACCGCCGGCAAGCTCGACGCGCTGGAGGAGCGGCTCCGCCCCTTCGGCATCCAGGAACTCTGCCGCTCG
GGGCGCATCGCGCTCGAGCGGGGCTTCAAGACGCTGGCTCCCCCCTCACTGAAGTAG

Upstream 100 bases:

>100_bases
GGCCCCACCATCGTGGACGTCCGGATCCGGCGCGAGGAGAAGGTGTACCCGATGGTGCCGGCCGGTGCCCCCCTCAACGA
CATGATCGACGGTGAGTGAC

Downstream 100 bases:

>100_bases
AGGAACGAACATGGCGACCATCTATTACGACAAGGACGCGAACCTCGACCTCCTGAAGAAGCGGAAGGTCGCGATCATCG
GCTACGGCTCGCAGGGCCAC

Product: acetolactate synthase, small subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MERTETPQPNGSTHTISLLVENKPGVLHRIAGLFSRRGYNIASLTVGPTERAEYSRMTIVVRLSSSPVDQVVRQVQKLVP
VVEVRELSPQDLIERELLLAKIRTPERNHAELRALAETYEAVIVDVSPDALVVEASGTAGKLDALEERLRPFGIQELCRS
GRIALERGFKTLAPPSLK

Sequences:

>Translated_178_residues
MERTETPQPNGSTHTISLLVENKPGVLHRIAGLFSRRGYNIASLTVGPTERAEYSRMTIVVRLSSSPVDQVVRQVQKLVP
VVEVRELSPQDLIERELLLAKIRTPERNHAELRALAETYEAVIVDVSPDALVVEASGTAGKLDALEERLRPFGIQELCRS
GRIALERGFKTLAPPSLK
>Mature_178_residues
MERTETPQPNGSTHTISLLVENKPGVLHRIAGLFSRRGYNIASLTVGPTERAEYSRMTIVVRLSSSPVDQVVRQVQKLVP
VVEVRELSPQDLIERELLLAKIRTPERNHAELRALAETYEAVIVDVSPDALVVEASGTAGKLDALEERLRPFGIQELCRS
GRIALERGFKTLAPPSLK

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=158, Percent_Identity=41.7721518987342, Blast_Score=118, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319837, Length=215, Percent_Identity=29.3023255813954, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 19699; Mature: 19699

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTETPQPNGSTHTISLLVENKPGVLHRIAGLFSRRGYNIASLTVGPTERAEYSRMTIV
CCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEE
VRLSSSPVDQVVRQVQKLVPVVEVRELSPQDLIERELLLAKIRTPERNHAELRALAETYE
EEECCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVIVDVSPDALVVEASGTAGKLDALEERLRPFGIQELCRSGRIALERGFKTLAPPSLK
EEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHCCCHHCCCCCCC
>Mature Secondary Structure
MERTETPQPNGSTHTISLLVENKPGVLHRIAGLFSRRGYNIASLTVGPTERAEYSRMTIV
CCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEE
VRLSSSPVDQVVRQVQKLVPVVEVRELSPQDLIERELLLAKIRTPERNHAELRALAETYE
EEECCCCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVIVDVSPDALVVEASGTAGKLDALEERLRPFGIQELCRSGRIALERGFKTLAPPSLK
EEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]