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The map label for this gene is nuoA [H]

Identifier: 220916485

GI number: 220916485

Start: 1544188

End: 1544577

Strand: Direct

Name: nuoA [H]

Synonym: A2cp1_1379

Alternate gene names: 220916485

Gene position: 1544188-1544577 (Clockwise)

Preceding gene: 220916473

Following gene: 220916486

Centisome position: 30.7

GC content: 65.64

Gene sequence:

>390_bases
ATGCTGACACCCCTGCAGATCTACTTCCCGATCGGTGTAGTCCTGCTGGTGGCGGTCGTACTCGCCTTCACGATGCTCGG
CCTGGCCAACGTGCTCGGACCGCGCAGACCCAGCCTGGTGAAGCAGACCCCGTTCGAGTGCGGGTCGGAGCCGGTCGGCT
CCGCGCGCGAGCGGTTCGGCGTGAAGTTCTACGTCGTCGCGCTGCTCTTCATCGTGTTCGACATCGAGGCGATCTTCCTT
TACCCGTGGGCGGTGCTGCTGCTGCCGGACGGCCAGGGCTATCCCGGCCTCGGCTGGCCCGGCTTCGTCTCCATGGGGAT
CTTCGTGTTCACCCTGGTCGCGGGCCTCGTCTACGTCTGGAAGAAGGGCGTCCTCGACTGGGCGGATTAG

Upstream 100 bases:

>100_bases
TCTACAGAAGGGGAACCTGATGTCAAGGGGTGGAAACCCGTTGACAAAGGCCATTGGGGCGGGCACTTAACGGGCTCCCC
ACCCCGACCAGTACCCACCT

Downstream 100 bases:

>100_bases
AGAGGAGCGACCGCACAATGGCATCGGAGCTCGACGGGCTGCCCGTCATCGCCACGCGCCGGGAGGAGGCGGAGGGGTTC
CTCCAGGGCCTCGTCTCGAA

Product: NADH-ubiquinone/plastoquinone oxidoreductase chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MLTPLQIYFPIGVVLLVAVVLAFTMLGLANVLGPRRPSLVKQTPFECGSEPVGSARERFGVKFYVVALLFIVFDIEAIFL
YPWAVLLLPDGQGYPGLGWPGFVSMGIFVFTLVAGLVYVWKKGVLDWAD

Sequences:

>Translated_129_residues
MLTPLQIYFPIGVVLLVAVVLAFTMLGLANVLGPRRPSLVKQTPFECGSEPVGSARERFGVKFYVVALLFIVFDIEAIFL
YPWAVLLLPDGQGYPGLGWPGFVSMGIFVFTLVAGLVYVWKKGVLDWAD
>Mature_129_residues
MLTPLQIYFPIGVVLLVAVVLAFTMLGLANVLGPRRPSLVKQTPFECGSEPVGSARERFGVKFYVVALLFIVFDIEAIFL
YPWAVLLLPDGQGYPGLGWPGFVSMGIFVFTLVAGLVYVWKKGVLDWAD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=120, Percent_Identity=41.6666666666667, Blast_Score=94, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14182; Mature: 14182

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPLQIYFPIGVVLLVAVVLAFTMLGLANVLGPRRPSLVKQTPFECGSEPVGSARERFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHC
VKFYVVALLFIVFDIEAIFLYPWAVLLLPDGQGYPGLGWPGFVSMGIFVFTLVAGLVYVW
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KKGVLDWAD
HHCCCCCCC
>Mature Secondary Structure
MLTPLQIYFPIGVVLLVAVVLAFTMLGLANVLGPRRPSLVKQTPFECGSEPVGSARERFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHC
VKFYVVALLFIVFDIEAIFLYPWAVLLLPDGQGYPGLGWPGFVSMGIFVFTLVAGLVYVW
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KKGVLDWAD
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA