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The map label for this gene is atoS [H]

Identifier: 220915778

GI number: 220915778

Start: 733990

End: 735567

Strand: Direct

Name: atoS [H]

Synonym: A2cp1_0659

Alternate gene names: 220915778

Gene position: 733990-735567 (Clockwise)

Preceding gene: 220915777

Following gene: 220915779

Centisome position: 14.59

GC content: 74.97

Gene sequence:

>1578_bases
ATGAGCGGATCCGGGGCAGAGCCGGGGCTGCACCGAAAGCTCGTCTGGCTCACGTTCTTCCGCCTGGTGACCGTGACCGT
GCTGCTCGGCGGCACGGCCCTGGTCGGCTGGCAGGTCGGCGGAGAGGCGGGCTCGTACCTCGCGCCGCTGTACGGCGTCG
TCGCCGCGACGTACGCGGGCTCGCTGGTGTTCGCCGTGGCGCTGCGCCGAAACGCCGGCCTGGTGGCGGTCGCGTACGCG
CAGATCGCGCTCGACGTGGCGATCGCGTCCGCGGTGGGGTCGCTCACCGGCGGCGTCGAGAGCGTGTTCGTCTTCATGTT
CTCGCTGGCGGTCGTGAACGGCGCGATCCTGCTGTACCGCCGCGGCGCCATCGCCGCCGCGGGCATGGCGCTGCTCGGGT
ACCTCGTCATGCTCGCCGCCACCTGGCGCCCCGGCTCGGCGCCGGTGGTGACCGTGTTCGCGCACGGCGGCGCGTTCCTG
GTGACGGCGGCGCTCGCGTCCTATCTCGCCGAGCTGCTCCGCAGCACCGGCGAGCGCCTGGCGGAGCGCGAGGGCGACCT
CGAGGCCATCACGGCGTTGCACGAGTCGATCGTGCAGTCGCTGACCAGCGGGCTGGTGACGGTCGATCGCGCAGAGCGCG
TGACGTTCCTGAACGTCGCGGCCGAGCAGGTGACCGGGATCCCGCTGGCGCGCGCGCTCGGGCGGCCCATCCGCGAGGTG
CTGCCGCTCCAGGCGGGCACCGGCCGGGACGAGGTCGAGTGGGTGAACGCCCGGGGCGAGCGGCTCACCTTGGGCTACAC
CGTCTTCCCGCTGATGGGGCGGGCCGGCGCGGAGATCGGGTCGGCGGCCATCTTCCAGGACCTCACGCGGCTGCGGGCCA
TGGAGCAGGCCTTCCAGCGCAGCGAGCGGCTGGCAGACCTGGGACGCGTCGCGGCCGGTCTCGCCCACGAGCTGCGCAAC
CCGCTCGCCTCCATGGCGGGATCGGTGGAGCTGCTGCGGGCGCAGGCGCCGCTCGGCGGCGACGAGCGGCGGCTCCTCGA
CATCGTGCTCCGCGAGGCGTCGCGCCTGGACGAGCTCGTCACCGAGTTCCTCCGCTTCGCGCGTCCGGCCCCGCTGCGGC
CCGGCGCGGTGGACCTGGCCAGCCTGCTCGAGGACGCCCTGCGCGTGTTCACGAACGATCCCGCCGCCGCCGGGCTGGTC
CTGTCGCGCGAGATCTCCCCGGCGCCGGCGGCCTGCGACCCGGACCAGATCCGGCAGGTGGTCTGGAACCTGCTGCGCAA
CGCGGCGCAGGCGCTCGGGGGGCGCGGGGGGCGCATCGCGGTCGCGTGCGGCGGCGAGGACGGCGGCGCCTGGTTCGCGG
TCGAGGACGACGGGCCGGGCATCCCGCCGGCGGAGCGGGAGCGCATCTTCCTTCCGTTCCACACCACCAAGGAGCGCGGA
ACCGGCCTCGGACTCGCAGTGGTGCAGCGGATCGTGGACGCGCACGGAGGGCGGGTCGAGGTGCGCTCCGCCCCGGGCCA
GGGCGCCCGGTTCACGGTCCACCTGCCCGGGCCCGCGCGCGCGGCGGAGACAGGGTAG

Upstream 100 bases:

>100_bases
CTGATGATGGTGTTCCTGGGCGGCACGGTCGGCTTCTTCATGATCGCGATGTACATGCCGATCTTCAACATCGCCGGGAC
CATCAAGTAGCCGAGTACGG

Downstream 100 bases:

>100_bases
GATCGGGGGGCCATGGCGAAGATCCTGGTGGTCGACGACGAGCAGTCGATGCGCGAGTTCCTCGAGATCCTGCTGCGCAA
GCAGGGCCACGAGGTGGTCG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MSGSGAEPGLHRKLVWLTFFRLVTVTVLLGGTALVGWQVGGEAGSYLAPLYGVVAATYAGSLVFAVALRRNAGLVAVAYA
QIALDVAIASAVGSLTGGVESVFVFMFSLAVVNGAILLYRRGAIAAAGMALLGYLVMLAATWRPGSAPVVTVFAHGGAFL
VTAALASYLAELLRSTGERLAEREGDLEAITALHESIVQSLTSGLVTVDRAERVTFLNVAAEQVTGIPLARALGRPIREV
LPLQAGTGRDEVEWVNARGERLTLGYTVFPLMGRAGAEIGSAAIFQDLTRLRAMEQAFQRSERLADLGRVAAGLAHELRN
PLASMAGSVELLRAQAPLGGDERRLLDIVLREASRLDELVTEFLRFARPAPLRPGAVDLASLLEDALRVFTNDPAAAGLV
LSREISPAPAACDPDQIRQVVWNLLRNAAQALGGRGGRIAVACGGEDGGAWFAVEDDGPGIPPAERERIFLPFHTTKERG
TGLGLAVVQRIVDAHGGRVEVRSAPGQGARFTVHLPGPARAAETG

Sequences:

>Translated_525_residues
MSGSGAEPGLHRKLVWLTFFRLVTVTVLLGGTALVGWQVGGEAGSYLAPLYGVVAATYAGSLVFAVALRRNAGLVAVAYA
QIALDVAIASAVGSLTGGVESVFVFMFSLAVVNGAILLYRRGAIAAAGMALLGYLVMLAATWRPGSAPVVTVFAHGGAFL
VTAALASYLAELLRSTGERLAEREGDLEAITALHESIVQSLTSGLVTVDRAERVTFLNVAAEQVTGIPLARALGRPIREV
LPLQAGTGRDEVEWVNARGERLTLGYTVFPLMGRAGAEIGSAAIFQDLTRLRAMEQAFQRSERLADLGRVAAGLAHELRN
PLASMAGSVELLRAQAPLGGDERRLLDIVLREASRLDELVTEFLRFARPAPLRPGAVDLASLLEDALRVFTNDPAAAGLV
LSREISPAPAACDPDQIRQVVWNLLRNAAQALGGRGGRIAVACGGEDGGAWFAVEDDGPGIPPAERERIFLPFHTTKERG
TGLGLAVVQRIVDAHGGRVEVRSAPGQGARFTVHLPGPARAAETG
>Mature_524_residues
SGSGAEPGLHRKLVWLTFFRLVTVTVLLGGTALVGWQVGGEAGSYLAPLYGVVAATYAGSLVFAVALRRNAGLVAVAYAQ
IALDVAIASAVGSLTGGVESVFVFMFSLAVVNGAILLYRRGAIAAAGMALLGYLVMLAATWRPGSAPVVTVFAHGGAFLV
TAALASYLAELLRSTGERLAEREGDLEAITALHESIVQSLTSGLVTVDRAERVTFLNVAAEQVTGIPLARALGRPIREVL
PLQAGTGRDEVEWVNARGERLTLGYTVFPLMGRAGAEIGSAAIFQDLTRLRAMEQAFQRSERLADLGRVAAGLAHELRNP
LASMAGSVELLRAQAPLGGDERRLLDIVLREASRLDELVTEFLRFARPAPLRPGAVDLASLLEDALRVFTNDPAAAGLVL
SREISPAPAACDPDQIRQVVWNLLRNAAQALGGRGGRIAVACGGEDGGAWFAVEDDGPGIPPAERERIFLPFHTTKERGT
GLGLAVVQRIVDAHGGRVEVRSAPGQGARFTVHLPGPARAAETG

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=349, Percent_Identity=32.9512893982808, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=39.8230088495575, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1790300, Length=355, Percent_Identity=31.2676056338028, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789808, Length=250, Percent_Identity=32, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994928, Length=269, Percent_Identity=27.8810408921933, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=30.1369863013699, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790567, Length=337, Percent_Identity=28.1899109792285, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=401, Percent_Identity=24.1895261845387, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=30.0925925925926, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=217, Percent_Identity=30.8755760368664, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=260, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=31.390134529148, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=31.0483870967742, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=29.3436293436293, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=28.3185840707965, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55102; Mature: 54971

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSGAEPGLHRKLVWLTFFRLVTVTVLLGGTALVGWQVGGEAGSYLAPLYGVVAATYAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
SLVFAVALRRNAGLVAVAYAQIALDVAIASAVGSLTGGVESVFVFMFSLAVVNGAILLYR
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEEE
RGAIAAAGMALLGYLVMLAATWRPGSAPVVTVFAHGGAFLVTAALASYLAELLRSTGERL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
AEREGDLEAITALHESIVQSLTSGLVTVDRAERVTFLNVAAEQVTGIPLARALGRPIREV
HHCCCCHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCHHHHHHCHHHHHH
LPLQAGTGRDEVEWVNARGERLTLGYTVFPLMGRAGAEIGSAAIFQDLTRLRAMEQAFQR
HCCCCCCCCCCHHEECCCCCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SERLADLGRVAAGLAHELRNPLASMAGSVELLRAQAPLGGDERRLLDIVLREASRLDELV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TEFLRFARPAPLRPGAVDLASLLEDALRVFTNDPAAAGLVLSREISPAPAACDPDQIRQV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCHHHHHHH
VWNLLRNAAQALGGRGGRIAVACGGEDGGAWFAVEDDGPGIPPAERERIFLPFHTTKERG
HHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCC
TGLGLAVVQRIVDAHGGRVEVRSAPGQGARFTVHLPGPARAAETG
CCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SGSGAEPGLHRKLVWLTFFRLVTVTVLLGGTALVGWQVGGEAGSYLAPLYGVVAATYAG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
SLVFAVALRRNAGLVAVAYAQIALDVAIASAVGSLTGGVESVFVFMFSLAVVNGAILLYR
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEEE
RGAIAAAGMALLGYLVMLAATWRPGSAPVVTVFAHGGAFLVTAALASYLAELLRSTGERL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
AEREGDLEAITALHESIVQSLTSGLVTVDRAERVTFLNVAAEQVTGIPLARALGRPIREV
HHCCCCHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCHHHHHHCHHHHHH
LPLQAGTGRDEVEWVNARGERLTLGYTVFPLMGRAGAEIGSAAIFQDLTRLRAMEQAFQR
HCCCCCCCCCCHHEECCCCCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SERLADLGRVAAGLAHELRNPLASMAGSVELLRAQAPLGGDERRLLDIVLREASRLDELV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TEFLRFARPAPLRPGAVDLASLLEDALRVFTNDPAAAGLVLSREISPAPAACDPDQIRQV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCHHHHHHH
VWNLLRNAAQALGGRGGRIAVACGGEDGGAWFAVEDDGPGIPPAERERIFLPFHTTKERG
HHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCC
TGLGLAVVQRIVDAHGGRVEVRSAPGQGARFTVHLPGPARAAETG
CCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]