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The map label for this gene is ptxB [H]

Identifier: 220915605

GI number: 220915605

Start: 557322

End: 558173

Strand: Direct

Name: ptxB [H]

Synonym: A2cp1_0486

Alternate gene names: 220915605

Gene position: 557322-558173 (Clockwise)

Preceding gene: 220915604

Following gene: 220915606

Centisome position: 11.08

GC content: 69.01

Gene sequence:

>852_bases
ATGCACCGCATCGCCGCCCTCGCCGTCGCCGCCGTCCTGCTCTTCCCGCCCGCCGCGCGCGCGCTCGACGCGCTGCGGGT
CAGCGCCATCCCCGACGAGTCGCCCACCGAGCTGCAGCGAAAGTTCGAGCCGCTCGGCAAGTACCTCGAGAAGCAGATCG
GCATCCCGGTGAAATTCGTGCCGGTGACCGACTACGCCGCCACGGTCGAGGGCCTCGCCGCCGGCAAGCTCGACATGGTC
TGGTACGGCGGCTTCACGTTCGTGCAGGCGCGGCGCCGCACCGGGAACGCCATCCCGCTCGTGCAGCGCGCCGAGGACGC
CCGCTTCCACTCCAAGTTCATCGTGCCCTCGGCGTCCAAGGCGCAGTCGCTGAAGGACCTGAAGGGCGGGAGCTTCGCGT
TCGGCTCGGTGAGCTCGACGTCCGGCCACCTCATGCCGCGCTACTTCCTGCTCCAGACCGGCATCGATCCCGACACGGAC
TTCGGCAAGGTCGCGTACTCCGGCGCGCACGACGTGACCGCGAAGTGGGTGGAGGCCGGCAAGGTGGACGCCGGCGCGCT
GAACGAGTCGATCTGGCAGCGGCTGGTGGACGAGAAGAAGATCGACACCAGCAAGGTCCGCGTCCTGTGGACCACGCCCG
AGTACCAGGACTACAACTGGACCGTCCGCGGCGACCTCGACCCGAAGCTCGTCGAGATGCTCCGCGCCGCGTTCCTCGCG
CTCGATCCCGCGAAGCCCGAGGACAAGGCCATCCTCGACCTGCAGCGCGCCAGCCGCTTCATCCCCACCTCGCCCGACGC
GTACAAGAACATCGAGCAGGCCGCGAAGTCGGCGGGGCTCATCAAGGACTGA

Upstream 100 bases:

>100_bases
CCGAGAGGCCCGCGGGGCGAGTTCGCCCCGGCACGTTCGCAGCAGCCCGAATGCTTCTCACCTCCGGCGCGCCCGCGCCG
GTACCACCGGAGCGTCCTTC

Downstream 100 bases:

>100_bases
GGTCGGGCGGCCCGTGCGCGCGGCGCGGTCCTCGGGCCCGGCGCGTGCCCGGACTTCATCCGCGACCCGGCGGCGACGAG
ATTGGGTCCGTGCCCAGCGC

Product: phosphonate ABC transporter periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MHRIAALAVAAVLLFPPAARALDALRVSAIPDESPTELQRKFEPLGKYLEKQIGIPVKFVPVTDYAATVEGLAAGKLDMV
WYGGFTFVQARRRTGNAIPLVQRAEDARFHSKFIVPSASKAQSLKDLKGGSFAFGSVSSTSGHLMPRYFLLQTGIDPDTD
FGKVAYSGAHDVTAKWVEAGKVDAGALNESIWQRLVDEKKIDTSKVRVLWTTPEYQDYNWTVRGDLDPKLVEMLRAAFLA
LDPAKPEDKAILDLQRASRFIPTSPDAYKNIEQAAKSAGLIKD

Sequences:

>Translated_283_residues
MHRIAALAVAAVLLFPPAARALDALRVSAIPDESPTELQRKFEPLGKYLEKQIGIPVKFVPVTDYAATVEGLAAGKLDMV
WYGGFTFVQARRRTGNAIPLVQRAEDARFHSKFIVPSASKAQSLKDLKGGSFAFGSVSSTSGHLMPRYFLLQTGIDPDTD
FGKVAYSGAHDVTAKWVEAGKVDAGALNESIWQRLVDEKKIDTSKVRVLWTTPEYQDYNWTVRGDLDPKLVEMLRAAFLA
LDPAKPEDKAILDLQRASRFIPTSPDAYKNIEQAAKSAGLIKD
>Mature_283_residues
MHRIAALAVAAVLLFPPAARALDALRVSAIPDESPTELQRKFEPLGKYLEKQIGIPVKFVPVTDYAATVEGLAAGKLDMV
WYGGFTFVQARRRTGNAIPLVQRAEDARFHSKFIVPSASKAQSLKDLKGGSFAFGSVSSTSGHLMPRYFLLQTGIDPDTD
FGKVAYSGAHDVTAKWVEAGKVDAGALNESIWQRLVDEKKIDTSKVRVLWTTPEYQDYNWTVRGDLDPKLVEMLRAAFLA
LDPAKPEDKAILDLQRASRFIPTSPDAYKNIEQAAKSAGLIKD

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=262, Percent_Identity=26.7175572519084, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 31077; Mature: 31077

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIAALAVAAVLLFPPAARALDALRVSAIPDESPTELQRKFEPLGKYLEKQIGIPVKFV
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
PVTDYAATVEGLAAGKLDMVWYGGFTFVQARRRTGNAIPLVQRAEDARFHSKFIVPSASK
ECCCHHHHHHHHHCCCEEEEEECCHHEEHHHHHCCCCCCHHHHHHHHHHHHEEECCCCHH
AQSLKDLKGGSFAFGSVSSTSGHLMPRYFLLQTGIDPDTDFGKVAYSGAHDVTAKWVEAG
HHHHHHCCCCCEEECCCCCCCCCCCHHHEEEECCCCCCCCCCCEEECCCCHHHHHHHHCC
KVDAGALNESIWQRLVDEKKIDTSKVRVLWTTPEYQDYNWTVRGDLDPKLVEMLRAAFLA
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHH
LDPAKPEDKAILDLQRASRFIPTSPDAYKNIEQAAKSAGLIKD
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHRIAALAVAAVLLFPPAARALDALRVSAIPDESPTELQRKFEPLGKYLEKQIGIPVKFV
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
PVTDYAATVEGLAAGKLDMVWYGGFTFVQARRRTGNAIPLVQRAEDARFHSKFIVPSASK
ECCCHHHHHHHHHCCCEEEEEECCHHEEHHHHHCCCCCCHHHHHHHHHHHHEEECCCCHH
AQSLKDLKGGSFAFGSVSSTSGHLMPRYFLLQTGIDPDTDFGKVAYSGAHDVTAKWVEAG
HHHHHHCCCCCEEECCCCCCCCCCCHHHEEEECCCCCCCCCCCEEECCCCHHHHHHHHCC
KVDAGALNESIWQRLVDEKKIDTSKVRVLWTTPEYQDYNWTVRGDLDPKLVEMLRAAFLA
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHH
LDPAKPEDKAILDLQRASRFIPTSPDAYKNIEQAAKSAGLIKD
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]