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The map label for this gene is phnE [H]

Identifier: 220915604

GI number: 220915604

Start: 555416

End: 557146

Strand: Direct

Name: phnE [H]

Synonym: A2cp1_0485

Alternate gene names: 220915604

Gene position: 555416-557146 (Clockwise)

Preceding gene: 220915603

Following gene: 220915605

Centisome position: 11.04

GC content: 78.86

Gene sequence:

>1731_bases
GTGAGCCAGGCCGCCTTGCACGAGCGCCCGCCGCTCCCGCTCCTGCTCCGCTGGCCGGGCCTCGTGCTCGCCGCCGTGCT
GGGGATCGCCTGGCGCATGTCGGAGGGGAGCCTCGGGGCCCTGCTCGCGCCCGAGGCCCGGTCGGCCGCGGCGGAGTTCG
CGCGCGGCTTCTGGCCGCCGGCGCACTCGCCTGCGTTCCTCCGCTTCCTGGCCCGGCCGCTCGCCGAGACCGTCGCCATC
GCGTTCGCCGGCATGACGCTCGCGCTCGTGCTCGCCGCGCCGCTCGCGTACCTCGCGACCGCGCCGGACGTCGGCCGGGT
CCGGGGCGACGCGCCGGGGCCGCTGCGCCGAGCGGCGTGGATCGGTGCGCGCACGGTGCTCAACCTGATGCGCTCCGTCC
CGGAGCTGGTCTGGGCGCTCGTGTTCGTGCGCGCGCTCGGGCTCGGGCCGGCCGCAGGGGTGGCGGCCATCGGGATCGGG
TACGCGGGCGTGGTCGGGAAGGTGTTCGCCGAGATCTGGGAATCCTCGCCCTGCGCGCCGGCCCGCGCGCTCGCCGCCGC
CGGGGCGCCGCCGCGCCGCGCCTTCGCGCTGGCGGTGCTGCCCGGGTCGGCGCCGCTGCTCGCCTCCTACGCGCTCTACC
GGCTCGACTGCGCGCTCCGGGCCTCGGCGGTGCTGGGGCTGGTGGGGGCGGGCGGGATGGGCGTGCAGCTCGAGCTGTCG
CTCAAGATGTTCGCGTACGACGAGGTGGCGACGCTGGTGCTGGCGCTGTTCGCGGTGGTGGCCGCGGTGGACCTCCTCTC
CGCCTGGGCCCGCCGGCGCCTCGCGGAGAGCCGCGGGCTCTATCCGGCCGGCCCGGGCGCGCTCCGCTGGCGCGCGGCGA
TCCTGGGCACCTGGCTCGCGCTCGCCGCCGGCGCGGCCGCGTACCTCGAGCTGCCGCTCGGCGAGCTGTTCTCCGGGGCC
ACGCTGCGGAGCGCGGCAGCCTTCTTCGGCTCGATGTTCCCGCCCGACCTCTCGCCCGGCTTCCTGCGCGGGCTCGCCCC
CGCCGTGGCCGAGACGCTGGCGGTGAGCGTGCTCGGGAGCGCCCTCGCGTCGGTCCTCGGGCTCGGCCTCGCGCTGGCCG
CGGTCCACCCCGGCGCGCGCGGCCTGGCCGGCGCGCCGGGCGACTCGCGCCTGCGGGCCGGGGCGCGGCTCGCGGTCACG
GCGGGCGCCCGCGGCGCCATGAACCTGCTCCGGACGCTGCCGGAGCTGCTGTGGGCGCTCGTCGCGATCTTCGCGGTGGG
CCTGGGCCCGTTCGCGGGCGCGCTCGCGCTCGGCATCCACAACGCCGGCGTGCTCGGGCGGCTCTACGCCGAGGCGCTCG
AGGAGGTGCCGCCCGGCCCGGTGGCGGCGCTCCGCGGCGCCGGGGCGCGCCCGCTCGCGGCGACGCTGCTCGGCGCGCTG
CCGCAGGCCTGGCCGCAGCTCGTCGCGTACACGCTCTACCGGTGGGAGGTGGCGGTCCGCGCCTCGGCGGTGCTCGGCGT
GGTGGGGGCGGGCGGCATCGGCGCGCTCCTGCACGTCTCGCTCAACCTGTTCCAGCACCACCGCACGCTCACGCTGGTCG
CCGCCATCGTGCTGCTCGTCACCGCGGTGGACCTGTTCTCCGGCTGGCTCCGGGCCCGCATCCTGGCGGGCCCCGCGAGC
CGCGCCGCGCCGCGCGCCGGCTGCGCGCCCGGGCTCGCGAATGCGACTTGA

Upstream 100 bases:

>100_bases
GCATCCCGCGCCACGTGTTCGCGGTGGCGCGGCGGAGCCCCGGGCCGAGCGCCGCGGCGCGCGCGTTCCTCGAGGTCGCG
CGCGCCGAGGTGCCGCCGGC

Downstream 100 bases:

>100_bases
GCCCGGCCCGGAAGCGAGAGGGGAGGTGAGCCGCGTGCAACGCATCGAGCAGCGCGTCCCGCTCGACGCCTGAGGCCGAG
AGGCCCGCGGGGCGAGTTCG

Product: phosphonate ABC transporter, inner membrane subunit

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MSQAALHERPPLPLLLRWPGLVLAAVLGIAWRMSEGSLGALLAPEARSAAAEFARGFWPPAHSPAFLRFLARPLAETVAI
AFAGMTLALVLAAPLAYLATAPDVGRVRGDAPGPLRRAAWIGARTVLNLMRSVPELVWALVFVRALGLGPAAGVAAIGIG
YAGVVGKVFAEIWESSPCAPARALAAAGAPPRRAFALAVLPGSAPLLASYALYRLDCALRASAVLGLVGAGGMGVQLELS
LKMFAYDEVATLVLALFAVVAAVDLLSAWARRRLAESRGLYPAGPGALRWRAAILGTWLALAAGAAAYLELPLGELFSGA
TLRSAAAFFGSMFPPDLSPGFLRGLAPAVAETLAVSVLGSALASVLGLGLALAAVHPGARGLAGAPGDSRLRAGARLAVT
AGARGAMNLLRTLPELLWALVAIFAVGLGPFAGALALGIHNAGVLGRLYAEALEEVPPGPVAALRGAGARPLAATLLGAL
PQAWPQLVAYTLYRWEVAVRASAVLGVVGAGGIGALLHVSLNLFQHHRTLTLVAAIVLLVTAVDLFSGWLRARILAGPAS
RAAPRAGCAPGLANAT

Sequences:

>Translated_576_residues
MSQAALHERPPLPLLLRWPGLVLAAVLGIAWRMSEGSLGALLAPEARSAAAEFARGFWPPAHSPAFLRFLARPLAETVAI
AFAGMTLALVLAAPLAYLATAPDVGRVRGDAPGPLRRAAWIGARTVLNLMRSVPELVWALVFVRALGLGPAAGVAAIGIG
YAGVVGKVFAEIWESSPCAPARALAAAGAPPRRAFALAVLPGSAPLLASYALYRLDCALRASAVLGLVGAGGMGVQLELS
LKMFAYDEVATLVLALFAVVAAVDLLSAWARRRLAESRGLYPAGPGALRWRAAILGTWLALAAGAAAYLELPLGELFSGA
TLRSAAAFFGSMFPPDLSPGFLRGLAPAVAETLAVSVLGSALASVLGLGLALAAVHPGARGLAGAPGDSRLRAGARLAVT
AGARGAMNLLRTLPELLWALVAIFAVGLGPFAGALALGIHNAGVLGRLYAEALEEVPPGPVAALRGAGARPLAATLLGAL
PQAWPQLVAYTLYRWEVAVRASAVLGVVGAGGIGALLHVSLNLFQHHRTLTLVAAIVLLVTAVDLFSGWLRARILAGPAS
RAAPRAGCAPGLANAT
>Mature_575_residues
SQAALHERPPLPLLLRWPGLVLAAVLGIAWRMSEGSLGALLAPEARSAAAEFARGFWPPAHSPAFLRFLARPLAETVAIA
FAGMTLALVLAAPLAYLATAPDVGRVRGDAPGPLRRAAWIGARTVLNLMRSVPELVWALVFVRALGLGPAAGVAAIGIGY
AGVVGKVFAEIWESSPCAPARALAAAGAPPRRAFALAVLPGSAPLLASYALYRLDCALRASAVLGLVGAGGMGVQLELSL
KMFAYDEVATLVLALFAVVAAVDLLSAWARRRLAESRGLYPAGPGALRWRAAILGTWLALAAGAAAYLELPLGELFSGAT
LRSAAAFFGSMFPPDLSPGFLRGLAPAVAETLAVSVLGSALASVLGLGLALAAVHPGARGLAGAPGDSRLRAGARLAVTA
GARGAMNLLRTLPELLWALVAIFAVGLGPFAGALALGIHNAGVLGRLYAEALEEVPPGPVAALRGAGARPLAATLLGALP
QAWPQLVAYTLYRWEVAVRASAVLGVVGAGGIGALLHVSLNLFQHHRTLTLVAAIVLLVTAVDLFSGWLRARILAGPASR
AAPRAGCAPGLANAT

Specific function: Part of the ABC transporter complex phnCDE involved in phosphate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005769 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 58676; Mature: 58545

Theoretical pI: Translated: 11.37; Mature: 11.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAALHERPPLPLLLRWPGLVLAAVLGIAWRMSEGSLGALLAPEARSAAAEFARGFWPP
CCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHCCCCC
AHSPAFLRFLARPLAETVAIAFAGMTLALVLAAPLAYLATAPDVGRVRGDAPGPLRRAAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHH
IGARTVLNLMRSVPELVWALVFVRALGLGPAAGVAAIGIGYAGVVGKVFAEIWESSPCAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ARALAAAGAPPRRAFALAVLPGSAPLLASYALYRLDCALRASAVLGLVGAGGMGVQLELS
HHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LKMFAYDEVATLVLALFAVVAAVDLLSAWARRRLAESRGLYPAGPGALRWRAAILGTWLA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LAAGAAAYLELPLGELFSGATLRSAAAFFGSMFPPDLSPGFLRGLAPAVAETLAVSVLGS
HHHCHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALASVLGLGLALAAVHPGARGLAGAPGDSRLRAGARLAVTAGARGAMNLLRTLPELLWAL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
VAIFAVGLGPFAGALALGIHNAGVLGRLYAEALEEVPPGPVAALRGAGARPLAATLLGAL
HHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHH
PQAWPQLVAYTLYRWEVAVRASAVLGVVGAGGIGALLHVSLNLFQHHRTLTLVAAIVLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVDLFSGWLRARILAGPASRAAPRAGCAPGLANAT
HHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQAALHERPPLPLLLRWPGLVLAAVLGIAWRMSEGSLGALLAPEARSAAAEFARGFWPP
CCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHCCCCC
AHSPAFLRFLARPLAETVAIAFAGMTLALVLAAPLAYLATAPDVGRVRGDAPGPLRRAAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHH
IGARTVLNLMRSVPELVWALVFVRALGLGPAAGVAAIGIGYAGVVGKVFAEIWESSPCAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ARALAAAGAPPRRAFALAVLPGSAPLLASYALYRLDCALRASAVLGLVGAGGMGVQLELS
HHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LKMFAYDEVATLVLALFAVVAAVDLLSAWARRRLAESRGLYPAGPGALRWRAAILGTWLA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LAAGAAAYLELPLGELFSGATLRSAAAFFGSMFPPDLSPGFLRGLAPAVAETLAVSVLGS
HHHCHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALASVLGLGLALAAVHPGARGLAGAPGDSRLRAGARLAVTAGARGAMNLLRTLPELLWAL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
VAIFAVGLGPFAGALALGIHNAGVLGRLYAEALEEVPPGPVAALRGAGARPLAATLLGAL
HHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHH
PQAWPQLVAYTLYRWEVAVRASAVLGVVGAGGIGALLHVSLNLFQHHRTLTLVAAIVLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVDLFSGWLRARILAGPASRAAPRAGCAPGLANAT
HHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA